Clinical trials: Thromboembolism Post-mechanical Valve Replacement
AORTIC VALVE DISEASES, Thromboembolism
Long-term Anticoagulation With Oral Factor Xa Inhibitor Versus Vitamin K Antagonist After Mechanical Aortic Valve Replacement
This study evaluates the long-term anticoagulation with oral factor Xa inhibitor versus vitamin K antagonist in patients receiving a mechanical aortic valve replacement.
- Trial name
- RENOVATE (NCT04258488)
- Testing
- Rivaroxaban Oral Tablet, Vitamin K antagonist(warfarin)
- Where
- 16 sites in South Korea
- Volunteers
- 1,300 people
- Sponsor
- Joon Bum Kim
Bleeding Post-mechanical Valve Replacement, Thromboembolism Post-mechanical Valve Replacement
Low INR to Minimize Bleeding With Mechanical Valves Trial
This study evaluates the use of a lower INR target (1.5 to 2.5) in patients with a mechanical bileaflet heart valve in the aortic position.
- Trial name
- LIMIT (NCT03636295)
- Testing
- Warfarin
- Where
- 45 sites in Belgium, Botswana and 16 more
- Volunteers
- 2,625 people
- Sponsor
- Population Health Research Institute