Clinical trials: Thrombosis, Deep Vein
Deep Vein Thrombosis
Ancillary Study of the ULTREC Project
The ULTREC research project is designed to assess the safety of a negative strategy relying on Colour Doppler Ultrasound (CDUS) for excluding the diagnosis of a new thrombosis.
- Trial name
- ULTRECAncillar (NCT05300139)
- Testing
- Color Doppler Ultrasound
- Where
- 12 sites in France
- Volunteers
- 18 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Central Venous Catheter Thrombosis
Autopsy and Photon Counting Computed Tomography to Evaluate Thromboses Related to Central Venous Catheters
Central venous (CVC) is essential in modern healthcare but unfortunately associated with complications, including thrombosis. In a recently published study, it was showed that 12 out of 12 deceased patients had subclinical…
- Trial name
- PHOTO CAT (NCT06417541)
- Testing
- Diseased patients with an indwelling central venous catheter who is referred to autopsy, Living patients with an indwelling central venous catheter referred to a CT scan without iv contrast
- Where
- Sweden
- Volunteers
- 75 people
- Sponsor
- Thomas Kander
Thrombosis
Low-Dose rtPA to Treat Blood Clots in Major Arm or Neck Veins
This study will test the effectiveness of low-dose recombinant tissue plasminogen activator (rtPA, or alteplase) in dissolving blood clots in major arm or neck veins.
- Trial name
- NCT00055159
- Testing
- Pulse-sprayed injection of recombinant tissue plasminogen activator (rtPA)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Venous Thromboses, Venous Thromboembolism
The Risk of Venous Thromboembolism in Systemic Inflammatory Disorders: a United Kingdom (UK) Matched Cohort Study
Blood clots occurring in the legs and in the lungs are relatively common; they occur in around 3 in a 1000 people per year. They can cause disability and are also potentially life threatening.
- Conditions
- Venous Thromboses, Venous Thromboembolism, Deep Vein Thrombosis, Pulmonary Embolism
- Trial name
- NCT03835780
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 266,890 people, healthy volunteers welcome
- Sponsor
- Momentum Data
Venous Thrombosis, Pregnancy
Prospective Assessment of the Deep Vein Thrombosis (DVT) in Hospitalized Obstetrics Patients
The purpose of the study is to prospectively assess the prevalence of venous thrombosis in women hospitalized for Cesarean Section, vaginal delivery or extended antepartum hospitalization by using Compression ultrasound of the…
- Trial name
- NCT02697123
- Testing
- antepartum and postpartum
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Baylor College of Medicine
Hip Arthroplasty, Total, Prevention of Venous Thromboembolism
ENhanced Recovery and ABbreviated LEngth of Anticoagulation for Thromboprophylaxis After Primary Hip Arthroplasty
Surgical hip replacement (total hip arthroplasty, THA) is associated with a high risk of venous thromboembolism, but the appropriate duration of postoperative medical thromboprophylaxis ("anticoagulation") remains highly…
- Trial name
- ENABLE-Hip (NCT06611319)
- Testing
- Prevention of Venous Thromboembolism
- Where
- 6 sites in Austria, Germany
- Volunteers
- 2,932 people
- Sponsor
- Prof. Stavros Konstantinides, MD
Heart Attack, Cardiac Arrest
Systematic Assessment and Targeted Improvement of Services Following Yearlong Surgical Outcomes Surveys
Based on limited published epidemiological data, up to an alarming 1 in 50 surgical inpatients die within 30 postoperative days.
- Conditions
- Heart Attack, Cardiac Arrest, Congestive Heart Failure, Atrial Fibrillation
- Trial name
- SATISFY-SOS (NCT02032030)
- Where
- United States
- Volunteers
- 73,952 people
- Sponsor
- Washington University School of Medicine
Venous Thromboembolic Diseases
Comparison of 2 Low Molecular Weight Heparin as a Thromboprophylaxis Postpartum
The use of a new generation low molecular weight heparin (Bemiparin)and the well known LMWH (Enoxaparin) after Caesarean sections and vaginal deliveries in a risky group patients for venous thrombosis.
- Trial name
- NCT01588171
- Testing
- Bemiparin, Enoxaparin
- Where
- Iraq
- Volunteers
- 7,020 people
- Sponsor
- Hawler Medical University
Venous Stasis, Deep Venous Thrombosis
Effects of External Leg Compression Devices on Healing and Blood Clotting
This study aims to compare two different external calf compression devices applied in healthy individuals. These devices are commonly used in medical care in order to prevent the formation of blood clots, for example during…
- Conditions
- Venous Stasis, Deep Venous Thrombosis, Healing Wound
- Trial name
- NCT03050671
- Testing
- Intermittent Pneumatic Compression, Rapid, Intermittent Pneumatic Compression, Slow
- Where
- Sweden
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Karolinska University Hospital
Deep Vein Thrombosis
Resolution Enhancement by a Supplemental Obstruction Lessening Venoactive Drug for Eight Weeks in Deep Vein Thrombosis
The RESOLVE-DVT study is a randomized single-center pilot study to determine the effects of hydroxyethylrutoside (Venoruton) on aspects of deep vein thrombosis (DVT) resolution associated with post-thrombotic syndrome (PTS).
- Trial name
- Resolve-DVT (NCT04670432)
- Testing
- Hydroxyethylrutoside
- Where
- Netherlands
- Volunteers
- 44 people
- Sponsor
- Maastricht University Medical Center
Venous Thrombosis
Neuromuscular Electrical Stimulation Versus Intermittent Pneumatic Compression for Blood Flow
Deep Vein Thrombosis (DVT) is a life threatening condition and a serious concern among hospitalized patients, with death occurring in approximately 6% of cases.
- Trial name
- NCT01862471
- Testing
- Neuromuscular Electrical Stimulation, Intermittent Pneumatic Compression
- Where
- Ireland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National University of Ireland, Galway, Ireland
Venous Thromboembolism, Deep Venous Thrombosis
Twice Daily Enoxaparin Prophylaxis in Reconstructive Surgery Patients
Blood clots that form in the extremities (deep venous thrombosis) and lungs (pulmonary embolus) are feared complications of reconstructive surgery.
- Conditions
- Venous Thromboembolism, Deep Venous Thrombosis, Pulmonary Embolus
- Trial name
- NCT02687204
- Testing
- Twice daily enoxaparin prophylaxis, Real time dose adjustment
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- University of Utah
Renal Failure Chronic Requiring Hemodialysis, Central Venous Catheterization
Duration and Adverse Events of Non-cuffed Catheter in Patients With Hemodialysis
The duration and adverse events of non-cuffed catheter in patients with hemodialysis will be investigated by multicenter prospective cohort.
- Conditions
- Renal Failure Chronic Requiring Hemodialysis, Central Venous Catheterization, Inadequate Hemodialysis Blood Flow, Venous Stenosis
- Trial name
- DACAPO (NCT02264964)
- Testing
- GamCath®, Arteriovenous fistula creation
- Volunteers
- 1,400 people
- Sponsor
- Shanghai Changzheng Hospital
Venous Thromboembolism, Deep Vein Thrombosis
Inter-observer Reliability of the TRiP(Cast) Score in Patients With Trauma to a Lower Limb Requiring Immobilisation
The aim of the study isto evaluate the inter-observer reliability of the assessment of venous thromboembolic risk using the TRiP(cast) score in patients presenting with trauma to a lower limb requiring immobilisation, and of the…
- Conditions
- Venous Thromboembolism, Deep Vein Thrombosis, Pulmonary Embolism, Thromboprophylaxis
- Trial name
- CCASTING (NCT06416280)
- Testing
- Assessment of the TRiP(cast) score
- Where
- France
- Volunteers
- 302 people
- Sponsor
- University Hospital, Angers
Thromboembolism
Applying Pharmacogenetic Algorithms to Individualize Dosing of Warfarin
The purpose of this study is to determine whether DNA analysis improves the efficiency of dosing and safety in patients who are being started on warfarin therapy.Warfarin, a blood thinner (anticoagulant) prescribed to 1-2 million…
- Trial name
- Coumagen-II (NCT00927862)
- Testing
- IWPC adapted genotype-guided dosing algorithm for warfarin, Modified IWPC genetic-guided warfarin dosing algorithm, Standard of care treatment
- Where
- United States
- Volunteers
- 2,415 people
- Sponsor
- Intermountain Health Care, Inc.
Venous Thromboembolism, Pulmonary Embolism
Exclusion of Venous Thrombo-Embolism With a New Clinical Decision Support
The goal of this non interventional study is to demonstrate the diagnostic performances on fresh plasmas in comparison with the performances on frozen plasmas in any patients with VTE suspicion, whatever the pre-test probability.
- Conditions
- Venous Thromboembolism, Pulmonary Embolism, Deep Vein Thrombosis
- Trial name
- EXTEND (NCT06480994)
- Testing
- Routine Assays on fresh plasma, New Clinical Decision Support on fresh plasma, New Clinical Decision Support on frozen plasma
- Where
- 4 sites in France
- Volunteers
- 1,836 people
- Sponsor
- Diagnostica Stago R&D
Deep Venous Thrombosis
Venous Thrombus Investigation With Contrast Enhanced Ultrasound Imaging
Background: During the repair process of deep venous thrombosis, capillary formation is seen from day 18 to day 25. Contrast agent investigation is well known to detect small vessels in arterial disease.
- Trial name
- NCT00677846
- Where
- Germany
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University Hospital Freiburg
May-Thurner Syndrome
Rivaroxaban for the Prevention of Deep Vein Thrombosis in Patients With Left Iliac Vein Compression - The PLICTS Study
The purpose of this study is to evaluate the efficacy and safety of rivaroxaban for the prevention of deep vein thrombosis in patients with left iliac vein compression treated with stent implantation.
- Trial name
- PLICTS (NCT04067505)
- Testing
- Rivaroxaban, Warfarin, Nadroparin
- Where
- 9 sites in China
- Volunteers
- 224 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
DVT - Deep Vein Thrombosis, VTE (Venous Thromboembolism)
Padua Prediction Score for VTE Risk in Thoracic Surgery Patients
The goal of this observational study is to assess the predictive accuracy of the Padua Prediction Score (PPS) for venous thromboembolism (VTE) risk in thoracic surgery patients.
- Trial name
- DVT (NCT06732726)
- Where
- Iraq
- Volunteers
- 150 people
- Sponsor
- Al-Nahrain University
Deep Vein Thrombosis (DVT), Pulmonary Embolism
Bemiparin as a Thromboprophylaxis After Gynaecological Surgeries
The use of prophylaxis for venous thromboembolism (VTE) remains grossly underused for women who undergo gynecologic surgery for benign conditions world wide and especially in developing countries including our region.
- Trial name
- NCT01630148
- Testing
- Bemiparin
- Where
- Iraq
- Volunteers
- 774 people
- Sponsor
- Hawler Medical University