Clinical trials: Thrombosis, Venous
Thrombosis, Thromboembolism
Assessment of Long-Term Out-of-Hospital Treatment of Patients With Proximal Deep Vein Thrombosis (DVT) Using Low-Molecular-Weight Heparin (LMWH) Versus LMWH Followed by Warfarin
The purpose of this study is to assess the long-term out-of-hospital treatment of patients with proximal venous thrombosis through the administration of subcutaneous low-molecular-weight heparin (tinzaparin sodium) versus…
- Conditions
- Thrombosis, Thromboembolism, Venous Thrombosis
- Trial name
- NCT00203658
- Testing
- Tinzaparin sodium
- Where
- Canada
- Volunteers
- 400 people
- Sponsor
- University of Calgary
Macular Edema, Cystoid
Dexamethasone Intravitreal Implant in Retinal Vein Occlusion
Purpose: To evaluate retinal functional improvement by means of visual acuity and retinal sensibility examination after intravitreal dexamethasone implant in patients affected by cystoid macular edema secondary to retinal vein…
- Trial name
- NCT03559491
- Testing
- Intravitreal injection
- Volunteers
- 30 people
- Sponsor
- Università degli Studi dell'Insubria
Pulmonary Embolism, Deep Vein Thrombosis
Safety Study of the Angel™ Catheter in Subjects With Risk of Pulmonary Embolism
The Angel™ Catheter combines the functions of a vena cava filter and a multi-lumen central line catheter. The device is designed to be placed in the inferior vena cava via the femoral vein for the prevention of Pulmonary Embolism…
- Conditions
- Pulmonary Embolism, Deep Vein Thrombosis, Venous Thromboembolism
- Trial name
- NCT01403090
- Testing
- Angel Catheter
- Where
- 2 sites in Colombia
- Volunteers
- 8 people
- Sponsor
- BiO2 Medical
Thromboembolism
Hip Fracture Study of GSK576428 (Fondaparinux Sodium)
This study is requested by PMDA to confirm the efficacy and the safety for HFS.
- Trial name
- NCT00320424
- Testing
- Fondaparinux
- Volunteers
- 48 people
- Sponsor
- GlaxoSmithKline
Venous Thromboembolism
A Trial to Learn How Well REGN9933 Works for Preventing Blood Clots After Knee Replacement Surgery in Adult Participants
The primary objective of the study is to evaluate the efficacy of REGN9933 for the prevention of venous thromboembolism (VTE) after unilateral total knee arthroplasty (TKA), compared to enoxaparin The secondary objectives of the…
- Trial name
- NCT05618808
- Testing
- REGN9933, Enoxaparin, Apixiban
- Where
- 16 sites in Belgium, Bulgaria and 5 more
- Volunteers
- 373 people
- Sponsor
- Regeneron Pharmaceuticals
Venous Thromboembolism, Delivery of Health Care
Improving Venous Thromboembolism Prophylaxis
Preventing the formation of blood clots in the veins so they do not injure leg veins or travel to the lungs, also called venous thromboembolism prophylaxis (VTE-P) is an essential component of safe in-patient care, yet it is…
- Conditions
- Venous Thromboembolism, Delivery of Health Care, Quality Improvement
- Trial name
- NCT01304108
- Testing
- VTE-P Tollgate, BLAZE Pop up, Usual Care
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Intimate Partner Violence, Deep Vein Thrombosis (DVT)/Thrombophlebitis
Prevalence and Characteristics of Intimate Partner Violence Against Individuals Seeking Hematological Consultations
Intimate violence against individuals, which is particularly marked among women, is one of the most widespread human rights violations in the world.
- Conditions
- Intimate Partner Violence, Deep Vein Thrombosis (DVT)/Thrombophlebitis, Pulmonary Embolism and Thrombosis
- Trial name
- HEMATO-WAST (NCT06415968)
- Where
- France
- Volunteers
- 138 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Macular Edema, Retinal Vein Occlusion
Safety and Efficacy of AGN208397 in the Treatment of Macular Edema Associated With Retinal Vein Occlusion (RVO)
This study will evaluate the safety and efficacy of a single intravitreal injection of AGN208397 to treat Macular Edema associated with Retinal Vein Occlusion.
- Trial name
- NCT01027650
- Testing
- AGN208397 intravitreal injection, dexamethasone intravitreal implant
- Where
- 5 sites in United States, Australia and 3 more
- Volunteers
- 121 people
- Sponsor
- Allergan
Retinal Vein Occlusion, Macular Edema
Efficacy of an Intravitreal DEX Implant in Retinal Vein Occlusion Following Treatment With Anti-VEGF Injections.
To test the efficacy of a 0.7 mg intravitreal dexamethasone implant (Ozurdex®) on macular function and recalcitrant macular edema associated with retinal vein occlusion following treatment with 2 or more prior intravitreal…
- Trial name
- NCT01449682
- Testing
- Ozurdex
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Retina Macula Institute
Hepatocellular Carcinoma, Hepatocellular Cancer
Atezolizumab Plus Bevacizumab Alone or Combined with External Beam Radiotherapy for HCC with Macrovascular Invasion
The recent global IMbrave150 study evaluated the combination of atezolizumab and bevacizumab versus sorafenib in 501 patients with advanced or metastatic Hepatocellular Carcinoma (HCC).
- Conditions
- Hepatocellular Carcinoma, Hepatocellular Cancer, Hepatocellular Carcinoma Non-resectable, Hepatocellular Carcinoma Stage IV
- Trial name
- ALERT-HCC (NCT05992220)
- Testing
- Atezolizumab plus bevacizumab, combined EBRT to vascular invasion, Atezolizumab plus bevacizumab
- Where
- South Korea
- Volunteers
- 138 people
- Sponsor
- Asan Medical Center
Venous Thromboembolism
Phase IIa Venous Thromboembolism (VTE) Prevention Study In Total Knee Replacement (TKR)
This study was designed to assess the safety and efficacy of GW813893 in the prophylaxis of VTE following TKR and to provide evidence to enable the selection of the appropriate dose(s) and dose regimen of GW813893 for future…
- Trial name
- NCT00541320
- Testing
- GW813893
- Where
- 8 sites in United States
- Sponsor
- GlaxoSmithKline
Portal Vein Thrombosis
A Study of the Correlation Between Portal Vein Thrombosis and Prognosis of Liver Transplantation
The goal of this observational study is to investigate the correlation between portal vein thrombosis (PVT) and the prognosis of liver transplantation.
- Trial name
- NCT06513780
- Testing
- Observation
- Where
- China
- Volunteers
- 700 people
- Sponsor
- Ru-zhou Cai
Cerebral Vein Thrombosis
Rivaroxaban vs. Warfarin in CVT Treatment
Cerebral venous thrombosis (CVT) is an uncommon venous-type of stroke tends to affect younger patients with somewhat different risk factors and much better outcome compared to arterial strokes.
- Trial name
- RWCVT (NCT04569279)
- Testing
- Rivaroxaban, Warfarin
- Where
- Syria
- Volunteers
- 71 people
- Sponsor
- Damascus University
Glioma, Malignant
Efficacy and Safety of Rivaroxaban in the Prevention of Venous Thromboembolism in Glioma Patients
Glioma is a common brain tumor with a high risk of venous thromboembolism during treatment, especially in the months after surgery.
- Trial name
- NCT06196918
- Testing
- Rivaroxaban 10 MG
- Where
- 8 sites in China
- Volunteers
- 320 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Rupture, Venous Thromboembolism
Compression Treatment Effects on Complications and Healing of Achilles Tendon Rupture
This prospective randomized study aims to determine whether intermittent pneumatic compression (IPC), 75 patients, beneath functional bracing compared to treatment-as-usual in plaster cast, 75 patients, can reduce the Venous…
- Conditions
- Rupture, Venous Thromboembolism, Venous Thrombosis, Surgical Wound Infection
- Trial name
- NCT01317160
- Testing
- Intermittent pneumatic compression (IPC)
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Karolinska University Hospital
Atrial Fibrillation, Deep Vein Thrombosis
Randomized Trial of Interventions to Improve Warfarin Adherence
The purpose of this research study is to see if a lottery which provides the opportunity to win money, a reminder system using a "Med-eMonitor", or the combination of both might be useful in helping patients to achieve better…
- Conditions
- Atrial Fibrillation, Deep Vein Thrombosis, Dilated Cardiomyopathies
- Trial name
- WIN3 (NCT00904982)
- Testing
- Financial Incentive and Med-eMonitor, 2Med-eMonitor
- Where
- 2 sites in United States
- Volunteers
- 268 people
- Sponsor
- University of Pennsylvania
Unresectable Hepatocellular Carcinoma, Pembrolizumab
Phase Ib/II Trial of Combining Pembrolizumab and Lenvatinib With SBRT for HCC Patients With Portal Vein Thrombosis.
HCC patients with PVTT (main trunk or the first-degree branch) treated with the combination of pembrolizumab (Ketruda), lenvatinib (Lenvima), and SBRT.
- Conditions
- Unresectable Hepatocellular Carcinoma, Pembrolizumab, Lenvatinib, Stereotactic Body Radiotherapy
- Trial name
- NCT05286320
- Testing
- Lenvatinib/Pembrolizumab plus SBRT combinations
- Where
- Taiwan
- Volunteers
- 27 people
- Sponsor
- National Taiwan University Hospital
Cerebral Vein Thrombosis
Venous Sinus Thrombosis : Clinical Picture and Outcome
Cerebral venous sinus thrombosis (cvst) is an underdiagnosed neurological condition with variable clinical presentations and variable risk factors CVST is often an underdiagnosed cause of acute or slowly progressive neurological…
- Trial name
- NCT05211102
- Volunteers
- 50 people
- Sponsor
- Assiut University
Deep Vein Thrombosis, Blood Clots
Personalized Medicine Decision-Making in a Virtual Clinical Setting
Background: -How people respond to drugs depends in part on their genes. For some drugs, doctors can use an individuals genetic background to help in dosing the drug.
- Trial name
- NCT02108041
- Where
- 5 sites in United States
- Volunteers
- 196 people
- Sponsor
- National Human Genome Research Institute (NHGRI)
Venous Thrombosis
A Study of MK-2060 in Healthy Participants (MK-2060-016)
The goal of the study is to learn about the safety of MK-2060 and if people tolerate it when MK-2060 is given in different forms.
- Trial name
- NCT06582602
- Testing
- MK-2060
- Where
- 2 sites in United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
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