Clinical trials: Thrombosis, Venous
Stroke, Venous Thrombosis
Pharmacogenetic Dosing of Warfarin
Purpose: Warfarin is now the most commonly used oral anticoagulant. This drug has inter-individual variability due to the genetic polymorphisms in the warfarin metabolizing enzyme, CYP2C9 and warfarin target, VKORC1.
- Conditions
- Stroke, Venous Thrombosis, Atrial Fibrillation, Atrial Flutter
- Trial name
- NCT02065388
- Testing
- Standard of care dosing for warfarin, Genotype-guided dosingTaiwan algorithm for warfarin, Genotype-guided dosing IWPC algorithm for warfarin
- Where
- 3 sites in Taiwan
- Volunteers
- 300 people
- Sponsor
- Academia Sinica, Taiwan
Neovascular Age-related Macular Degeneration (nAMD)
Study to Evaluate the Safety and Effectiveness of Intravitreal Injections (IVI) of Brolucizumab in Patients With Neovascular Age-related Macular Degeneration (nAMD)
The purpose of this study was to generate additional safety and effectiveness data in Indian neovascular age-related macular degeneration (nAMD) patients that more closely resemble the real-world population intended to be treated…
- Trial name
- NCT05269966
- Testing
- Injection Brolucizumab
- Where
- 10 sites in India
- Volunteers
- 105 people
- Sponsor
- Novartis Pharmaceuticals
Non-Small Cell Lung Carcinoma, Venous Thromboembolism
Hypercoagulable Parameters as Predictors of Thrombotic Events and Prognosis in Patients With Advanced Non-Small Cell Lung Carcinoma
The association between cancer and thrombosis is well known and the occurrence of thrombotic complications is commonly associated with poor prognosis.
- Trial name
- NCT00192829
- Testing
- Blood sample withdrawal
- Where
- 2 sites in Israel
- Volunteers
- 100 people
- Sponsor
- Rambam Health Care Campus
Venous Thrombosis, Pulmonary Embolism
Use of Low Molecular Weight Heparin (Tinzaparin) to Treat Blood Clots in Patients With Kidney Failure
Blood clots in the leg veins, known as deep vein thrombosis, are important because they may travel to the lung (known as pulmonary embolism) and cause death. Blood clots are treated with blood thinners, or anticoagulants.
- Trial name
- NCT00186745
- Testing
- Tinzaparin
- Where
- Canada
- Volunteers
- 148 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Venous Thromboembolism, Cancer
Cancer Associated Thrombosis : What is the Proportion of Patients Ineligible to a Study as CARAVAGGIO
Venous thromboembolism is a common and fatal disease closely related to cancer. The therapeutic challenge is major due to the high risk of recurrent thromboembolism and bleeding in patients with cancer.
- Trial name
- NCT04846556
- Testing
- data collection
- Where
- 3 sites in France
- Volunteers
- 300 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Venous Thromboembolism, Surgery
GRACE: Evaluating Compression Stockings in Patients That Require Extended Duration Pharmacological Thromboprophylaxis
Individuals attending the hospital to undergo operations are at risk of developing blood clots in the legs, known as deep vein thrombosis (DVT). A clot in the leg can cause swelling, pain, and other long-term problems.
- Trial name
- GRACE (NCT06166537)
- Testing
- Graduated compression stockings, No Graduated compression stockings
- Where
- 3 sites in United Kingdom
- Volunteers
- 8,608 people
- Sponsor
- Imperial College London
Retinal Vein Occlusion
Retrospective Analysis of the Clinical Characteristics of Retinal Vein Occlusion
To explore the clinical characteristics of patients with RVO, and to analyze the relationship between RVO and various underlying diseases, ocular conditions, lifestyle, imaging findings and treatment response.
- Trial name
- NCT06757595
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Zhongnan Hospital
Portal Vein Thrombosis
Risk Factors and Management Outcome of Chronic Portal Vein Thrombosis in Children
The aim of study is to evaluate different etiological and risk factors that lead to chronic portal vein thrombosis and to delineate a management plan for chronic portal vein thrombosis in children.
- Trial name
- NCT06117488
- Testing
- endoscopy
- Volunteers
- 30 people
- Sponsor
- Assiut University
Portal Vein Thrombosis
Efficacy and Safety of Rivaroxaban in the Management of Acute Non-neoplastic PVT Compensated Cirrhosis
-Rivaroxaban is factor Xa inhibitor
- Trial name
- NCT03193502
- Testing
- rivaroxaban
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Sherief Abd-Elsalam
Deep Vein Thrombosis (DVT)
COMPARISON OF WARFARIN AND RIVAROXABAN IN THE TREATMENT OF LOWER LIMB DEEP VENOUS THROMBOSIS
This was a randomized controlled trial conducted at General Surgical wards of Mayo Hospital, Lahore.Total 74(37 in each group) patients were included.After heparinizing patients for 48 hours (80 units/kg/stat and 18…
- Trial name
- NCT07077954
- Testing
- Rivaroxaban, Warfarin
- Where
- Pakistan
- Volunteers
- 74 people
- Sponsor
- Children Hospital and Institute of Child Health, Lahore
Deep Venous Thrombosis
Radial, Sequential Compression Device Deep Venous Thrombosis Detection Study
The purpose of this study is to evaluate the effectiveness of a new leg compression device in preventing post-surgical deep vein thrombosis (blood clot) that can occur after major and complex spine surgery.
- Trial name
- NCT04232501
- Testing
- Cirvo Compression device
- Where
- United States
- Sponsor
- Stanford University
Venous Thrombosis or Pulmonary Embolism
What Treatment for Patients With Phlebitis or Pulmonary Embolism ?
The objective of the "anticoagchoice" study is to analyze the preferences of people suffering from phlebitis, in terms of anticoagulant, to improve adherence to these treatments, to adapt the medical prescriptions.
- Trial name
- AntiCoagChoice (NCT03889457)
- Testing
- anticoagulation choice
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Rennes University Hospital
Gynecologic Cancer, Venous Thromboembolism
Oral Apixaban (Eliquis) Versus Enoxaparin (Lovenox) for Thromboprophylaxis in Women With Suspected Pelvic Malignancy
The study will evaluate the incidence of major bleeding (including clinically relevant non-major (CRNM) bleeding) events in women undergoing surgery for gynecologic cancer with apixaban 2.5 mg twice a day (BID) compared to…
- Trial name
- NCT02366871
- Testing
- Oral apixaban, Subcutaneous enoxaparin
- Where
- 2 sites in United States
- Volunteers
- 400 people
- Sponsor
- University of Colorado, Denver
Venous Thromboembolism, Thromboprophylaxis
Aspirin and Enoxaparin for VTE in Trauma
The purpose of this study is to determine if the addition of antiplatelet therapy (i.e. aspirin) to low-molecular-weight-heparin (i.e.
- Conditions
- Venous Thromboembolism, Thromboprophylaxis, Trauma
- Trial name
- NCT02396732
- Testing
- Aspirin, Enoxaparin
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Miami
Deep Venous Thrombosis
Comparison Between Xarelto Versus Warfarin in the Recanalization Rate of Deep Venous Thrombosis in Patients Legs.
This is a prospective, randomized study, aiming to evaluate patients with Deep Venous Thrombosis in lower limbs and the recanalization rates evaluated with DUPLEX ultrasound, as so the clinical outcomes in patients submitted to…
- Trial name
- DVT (NCT02704598)
- Testing
- Rivaroxaban, Warfarin
- Where
- Brazil
- Volunteers
- 84 people
- Sponsor
- Hospital do Servidor Publico Estadual
Ileofemoral Deep Vein Thrombosis
Prevention of Recurrence After Thrombolysis in Acute Iliofemoral Venous Thrombosis (PRAIS) Study
The EINSTEIN program showed that oral rivaroxaban is effective and safe treatment for prevention of recurrent venous thrombosis and pulmonary embolism in deep vein thrombosis patients and FDA approved the rivaroxaban for…
- Trial name
- PRAIS (NCT01986192)
- Testing
- rivaroxaban, Warfarin
- Where
- South Korea
- Volunteers
- 72 people
- Sponsor
- Seoul National University Hospital
Venous Thromboembolism,, Pulmonary Embolism,
Using a Novel Algorithm to Improve the Retrieval Rate of Inferior Vena Cava Filters (iRetrieve Study)
Since 2003, that the first retrievable IVC filter was introduced in the U.S,improvements have been made in the filter design to resolve problems of structural integrity and increase the ability to remove the filter after longer…
- Conditions
- Venous Thromboembolism,, Pulmonary Embolism,, Deep Vein Thrombosis,
- Trial name
- iRetrieve (NCT02160964)
- Volunteers
- 1,786 people
- Sponsor
- Heart and Vascular Outcomes Research Institute
Macular Edema, Central Retinal Vein Occlusion
Conbercept Ophthalmic Injection for Patients of Central Retinal Vein Occlusion
This study evaluates the efficacy and safety of Conbercept ophthalmic injection. This is a multi-center, randomized, double-masked, placebo-controlled phase III clinical study.
- Trial name
- CRAVE (NCT03223714)
- Testing
- Conbercept Ophthalmic Injection
- Where
- 27 sites in China
- Volunteers
- 242 people
- Sponsor
- Chengdu Kanghong Biotech Co., Ltd.
Venous Thromboembolism
BIBR 1048 in the Prevention of Venous Thromboembolism in Patients Undergoing Primary Elective Total Hip Replacement Surgery
To determine the therapeutic window of BIBR 1048 in order to select doses for further studies in the development plan. Twice daily regimen will be tested for most dose levels and once daily administration will also be evaluated…
- Trial name
- NCT02170701
- Testing
- BIBR 1048
- Volunteers
- 289 people
- Sponsor
- Boehringer Ingelheim
Retinal Vein Occlusion, Macular Edema
A Long-Term Safety Study of OZURDEX® in Clinical Practice
This study is a multicenter, prospective, observational study to evaluate the long-term safety of OZURDEX® in patients with macular oedema following central retinal vein occlusion (CRVO) or branch retinal vein occlusion (BRVO) or…
- Conditions
- Retinal Vein Occlusion, Macular Edema, Uveitis, Posterior
- Trial name
- NCT01539577
- Testing
- dexamethasone 700 μg intravitreal implant
- Where
- 4 sites in France, Germany and 2 more
- Volunteers
- 875 people
- Sponsor
- Allergan
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.