Clinical trials: Thrombus
Thrombi, Thrombus, Brain
Glycoprotein IIb/IIIa PET/CT in Various GPIIb/IIIa-Related Disease
In the field of diagnosing Thrombi diseases, it is now a well established practice to inject positron-emitting tracers into the human body.
- Conditions
- Thrombi, Thrombus, Brain, Thrombus
- Trial name
- NCT07813559
- Testing
- 18F/68Ga-GP1
- Where
- 3 sites in China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University
Myocardial Injury, Atherosclerosis Cardiovascular Disease
Multimodal Biomarkers in Coronary Artery Disease Pathogenesis: The Oxford Acute Myocardial Infarction Study (OXAMI Study)
Coronary artery disease is one of the most common causes of illness and death. It develops when fatty deposits, known as plaques, build up in the arteries that supply blood to the heart.
- Conditions
- Myocardial Injury, Atherosclerosis Cardiovascular Disease, Cardiac Imaging Techniques, Genetics
- Trial name
- OXAMI (NCT07772570)
- Testing
- blood sampling, Intracoronary Imaging, Cardiovascular Magnetic Resonance Imaging
- Where
- United Kingdom
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Heart Diseases, Coronary Disease
CES1 Carriers in the PAPI Study
This study builds, in part, upon preliminary results generated as part of the Pharmacogenomics Anti-Platelet Intervention (PAPI) Study (NCT00799396).
- Conditions
- Heart Diseases, Coronary Disease, Coronary Artery Disease, Cardiovascular Diseases
- Trial name
- NCT03188705
- Testing
- Clopidogrel, Aspirin
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Left Ventricular Thrombus
Left Ventricular Thrombus Registry
Left Ventricular Thrombus (LVT) is a blood clot that can develop in a poorly functioning heart. In around 1 in 6 patients who have had a heart attack or diagnosed with heart failure tend to develop blood clots in their main heart…
- Trial name
- LVT Registry (NCT06963567)
- Where
- 8 sites in United Kingdom
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Thrombus
A Phase 1 Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SRSD107 in Healthy Chinese Subjects
This was a Phase 1, randomized, double-blind, placebo-controlled, single ascending dose study to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of subcutaneously administered SRSD107 in…
- Trial name
- NCT07655427
- Testing
- SRSD107
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Sirius Therapeutics Co., Ltd.
Platelet Function and Thrombus Formation
Zhongshan Ketogenic Diet Study 1
This dietary intervention study was designed to investigate the impact of a ketogenic diet on platelet function and and thrombus formation.
- Trial name
- NCT07117903
- Testing
- Normal diet + vehicle, Normal diet + aspirin, Ketogenic diet + vehicle
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Fudan University
Thrombosis, Blood Coagulation Disorder
Dynamics of Platelet Activation in Patients With Ventricular Assist Device (VAD)
Consenting patients with end-stage heart failure that are implanted with/candidates for implant of a short-term/durable mechanical circulatory support device (e.g.: percutaneous microaxial pumps (Impella), extracorporeal membrane…
- Conditions
- Thrombosis, Blood Coagulation Disorder, Platelet Thrombus, Platelet Dysfunction Due to Aspirin
- Trial name
- PASVAD (NCT03255928)
- Testing
- PAS assay, TGT
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Scientific Institute San Raffaele
Intraprosthetic Thrombus, Limb Graft Occlusion
Computational Fluid Dynamics Predicting Intraprosthetic Thrombus Formation and Progression Following EVAR
Intraprosthetic thrombus (IPT) formation and its progression to limb graft occlusion (LGO) are significant complications following endovascular aneurysm repair (EVAR).
- Trial name
- NCT06701773
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Xiangya Hospital of Central South University
Platelet Thrombus
Characterization of Exosomes Platelets-released
Extracellular vesicles (EVs) play a key role in cell-to-cell communication. They are small vesicles that contain rich molecular cargo. Recently, they have been proposed as biomarkers for clinical diagnostics.
- Trial name
- EXOPLT (NCT06298682)
- Where
- Italy
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Centro Cardiologico Monzino
Thrombus
The Multiple Dose of PK/PD Study of SHR2285 Tablets in Healthy Subjects
The study is a randomized, single-blind, placebo-controlled, multiple-dose escalation Phase I trials. 2 dose groups were designed, 12 subjects in each dose group.The drug was administered single dose and multiple doses.
- Trial name
- NCT04229433
- Testing
- SHR2285 tablet
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Platelet Thrombus
Anti-Inflammatory and Anti-Coagulant Effects of Salmon Polar Lipids
Inflammation is a normal immune response to tissue healing. However, uncontrolled and unresolved inflammation can initiate and further induce several chronic manifestations that contribute to chronic disorders such as…
- Trial name
- NCT03866265
- Testing
- Food Grade Extract of Salmon Polar Lipids (FGE-Salmon-PLs)
- Where
- Ireland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Limerick
Thrombus, Myocardial Infarction
Diagnostic Utility of Contrast Echocardiography for Detection of LV Thrombi Post ST Elevation Myocardial Infarction
This is a cross-sectional study of post myocardial infarction patients which is designed to determine the prevalence of left ventricular thrombi (blood clots) using non-contrast echocardiography and to compare this with the…
- Trial name
- NCT00539045
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Thrombosis, Thrombus Formation
Study in an Ex-vivo Thrombosis Model With Human Umbilical Vein Endothelial Cells (HUVEC)-Perfusion
Evaluation of fibrin and platelet deposition on a human umbilical endothelial cell surface in perfusion chamber experiments using human whole blood.
- Conditions
- Thrombosis, Thrombus Formation, Thrombus Stability
- Trial name
- HUVEC (NCT01020110)
- Where
- Austria
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna