Clinical trials: Thumb Arthritis
Osteoarthritis, Osteoarthritis Thumbs
Prospective Clinical Study to Evaluate the Safety and Efficacy of Intraarticular Administration of Micro-grafts of Adipose Tissue (Adipo-micro-grafts) in the Treatment of Osteoarthritis of the Trapezium-metacarpal Joint (ADIPO_MICRO_GRAFTS_1)
The objective of this interventional study is the Change in the Michigan Hand Questionnaire (MHQ) score over time in subjects with Eaton Littler grade II and III trapeziometacarpal osteoarthritis.
- Trial name
- AMG_1 (NCT06997991)
- Testing
- adipose micro-grafts injection
- Where
- Italy
- Volunteers
- 25 people
- Sponsor
- Azienda Ospedaliero, Universitaria Ospedali Riuniti
Thumb Osteoarthritis
Effectiveness of Intra-articular Oxygen-ozone Injections and Splinting for the Treatment of Thumb Osteoarthritis
Osteoarthritis of trapezio-metacarpal joint (TMJ) most commonly occurs in women over 50 years old, often bilateral and it is a disabling condition presenting with pain at base of the thumb, swelling, instability, deformity and…
- Trial name
- NCT07171840
- Testing
- 10 cc of oxygen-ozone plus thumb splint, thumb splint
- Where
- Italy
- Volunteers
- 43 people
- Sponsor
- Humanitas Clinical and Research Center
Thumb Osteoarthritis
Pulsed Electromagnetic Field (PEMF) Therapy in Thumb CMC Arthritis
Long-Term Objective: Determine if high-frequency PEMF therapy reduces pain in patients with thumb carpometacarpal (CMC) joint osteoarthritis (OA).
- Trial name
- NCT05315297
- Testing
- PEMF device
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Stanford University
Rheumatoid Arthritis.
The Effectiveness of a Nighttime Positioning Hand Splint in Patients With Rheumatoid Arthritis
The purpose of the present study was to evaluate the effectiveness of a nighttime positioning hand splint in patients with RA in terms of pain, grip and pinch strength, upper limb function, quality of life, and patient…
- Trial name
- NCT00502424
- Testing
- Splint
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Federal University of São Paulo
Rheumatoid Arthritis, Kinesiotape
Kinesiotaping Applied to the Thumb in Rheumatoid Hand
Objective: It was aimed to evaluate the acute effect of Kinesiotape taping on pain, function, range of motion and grip strength parameters in patients with rheumatoid arthritis and hand involvement.
- Conditions
- Rheumatoid Arthritis, Kinesiotape, Hand Deformity
- Trial name
- NCT05515965
- Testing
- Kinesiotaping
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Istanbul Arel University
Osteoarthritis
Use of Autologous Adipose-Derived Stromal Vascular Fraction To Treat Osteoarthritis of Hip, Knee, Ankle, and Thumb Joints
This study will examine the safety and efficacy of autologous adipose-derived stromal vascular fraction (SVF) cells for treatment of hip, knee and thumb osteoarthritis (OA); monitoring adverse events and measuring pain, function…
- Trial name
- NCT03166410
- Testing
- Cell injection
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Texas Plastic Surgery
Osteoarthritis in the Carpometacarpal (CMC) Joint
CMC-1 Replacement Arthroplasty Versus Trapeziectomy
Thumb carpometacarpal (CMC-1) osteoarthritis is a common condition causing pain and disability, particularly among middle-aged and older women. When non-operative treatment fails, surgery is indicated.
- Trial name
- NCT07583628
- Volunteers
- 1,000 people
- Sponsor
- Karolinska Institutet
Orthopedic Disorder
Arthroscopic Partial Trapezictomy With Hematoma Distraction in Basal Thumb Arthritis
The basal joint, also referred to as the carpometacarpal (CMC) joint, of the thumb is one of the joints most commonly affected by arthritis.
- Trial name
- NCT05746091
- Testing
- wrist arthroscopy
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Al-Azhar University
Osteoarthritis Thumb
Intra-articular Allocetra in Osteoarthritis of the 1st Carpo-metacarpal Joint
This study is a single center trial to assess the safety and efficacy of intra-articular administration of Allocetra to patients with 1st CMC thumb joint osteoarthritis (OA).
- Trial name
- NCT06459063
- Testing
- Allocetra - Safety run-in phase, Allocetra - Randomization phase
- Where
- Israel
- Volunteers
- 46 people
- Sponsor
- Kaplan Medical Center
Osteoarthrosis of the Carpometacarpal Joint of the Thumb
Postoperative Rehabilitation Following Trapeziectomy and Ligament Reconstruction Tendon Interposition
Carpometacarpal (CMC) arthritis of the thumb joint ('basal arthritis') is a common entity treated by hand surgeons in our society.
- Trial name
- LRTI (NCT01425034)
- Testing
- casts for the thumb, Motion group
- Where
- United States
- Volunteers
- 234 people
- Sponsor
- University of Utah
Thumb Osteoarthritis
NSAID Injection Versus Corticosteroid Injection for Basilar Thumb Arthritis
The Researchers are trying to compare two different types of intraarticular injections (injection in the joint) for treating the symptoms of moderate to advanced basilar thumb arthritis.
- Trial name
- NCT05992883
- Testing
- Ketorolac, Triamcinolone
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Mayo Clinic
Trapeziometacarpal Osteoarthritis, Thumb Carpometacarpal Osteoarthritis
Surgical Treatment for Trapeziometacarpal Osteoarthritis Eaton & Glickel Stage 2-3
Trapeziometacarpal osteoarthritis is a common cause of pain and loss of hand function in postmenopausal women. Many surgical treatments have been described and recent literature has show that the relatively simple trapeziectomy…
- Trial name
- NCT02204488
- Testing
- Total Joint Arthroplasty, Trapeziectomy
- Where
- Netherlands
- Volunteers
- 62 people
- Sponsor
- Isala
Thumb Osteoarthritis
Proprioceptive Thumb Exercises Program in Patients With Carpometacarpal Joint Osteoarthritis
Osteoarthritis (OA) is a chronic and prevalent joint disorder with great impact on quality of life and high economic burden. Although a number of conservative therapies have proven to be effective for the management of hand OA…
- Trial name
- thumb (NCT04738201)
- Testing
- Proprioceptive thumb exercises.
- Where
- Spain
- Volunteers
- 45 people
- Sponsor
- University of Malaga
Arthritis
Allograft Meniscal Arthroplasty for the Treatment of Basal Joint Arthritis of the Thumb
Hypothesis: The use of knee meniscal allograft as a joint spacer and stabilizer is a viable option for the surgical treatment of basal joint arthritis of the thumb.
- Trial name
- NCT01542515
- Testing
- Meniscal allograft arthroplasty of the carpometacarpal joint of the thumb
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Corewell Health East
Thumb Osteoarthritis, Pain
Laser Therapy, Pain and Carpometacarpal Joint Osteoarthritis Treatment
Osteoarthritis (OA) is a chronic and prevalent joint disorder with great impact on quality of life and high economic burden. Although a number of conservative therapies have proven to be effective for the management of hand OA…
- Conditions
- Thumb Osteoarthritis, Pain, Physical Disorder
- Trial name
- Laser (NCT03270488)
- Testing
- Laser
- Where
- Spain
- Volunteers
- 61 people
- Sponsor
- University of Malaga
Osteoarthritis Thumbs, Rhizarthrosis
Pinch Grip and Functional Outcomes Between Hematoma Distraction Arthroplasty Versus Ligament Reconstruction Tendon Interposition Arthroplasty in Trapeziometacarpal Osteoarthritis.
To date, there is no gold standard for the treatment of severe trapeziometacarpal joint osteoarthritis. Despite the fact that new procedures have been described, techniques such hematoma distraction or ligament reconstruction…
- Conditions
- Osteoarthritis Thumbs, Rhizarthrosis, Trapeziometacarpal (TMC) Arthrosis
- Trial name
- Rhizarthrosis (NCT06858800)
- Testing
- LTRI technique, HDA technique
- Where
- Spain
- Volunteers
- 96 people
- Sponsor
- Hospital de la Santa creu i Sant Pau - Barcelona
CMC Arthritis, Occupational Therapy
Trapeziectomy and Suture Suspensionplasty for Thumb Carpometacarpal Arthritis - Is In-Clinic Therapy Needed?
The study is a randomized, controlled trial to evaluate the efficacy of formal occupational therapy on outcomes following CMC arthroplasty
- Conditions
- CMC Arthritis, Occupational Therapy, Hand Arthritis
- Trial name
- NCT06820528
- Testing
- Occupational Therapy, Home Exercise Program
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Julie Nuelle
Arthritis
Autologous Intra-Articular Micro-Fragmented Adipose Transfer for the Treatment of Thumb Carpometacarpal Joint Arthritis
32 patients with Eaton-Glickel stage 2-3 CMC arthritis will be randomized to receive intraarticular MFAT or intraarticular corticosteroid injection.
- Trial name
- NCT05005000
- Testing
- Micro-Fragmented Adipose Tissue (MFAT), Triamcinolone Acetonide 10mg/mL
- Where
- United States
- Sponsor
- NYU Langone Health
Thumb Osteoarthritis
Postoperative Therapy After Interposition Arthroplasty in CMC1
In this randomized controlled trial the investigators want to investigate whether early versus late mobilisation after surgery in the first carpometacarpal joint (CMC1) leads to a faster recovery of hand function.
- Trial name
- NCT01679717
- Testing
- Early mobilisation after CMC1-surgery
- Where
- Norway
- Volunteers
- 70 people
- Sponsor
- Diakonhjemmet Hospital
Rizarthrosis
Comparative Study Between the Use of Trapeziometacarpal Prostheses and the Usual Resection-tenosuspension Arthroplasty for the Treatment of Rhizarthrosis, Focusing on Changes in Pain (Measured With the VAS Scale) and Function (With the Quick-DASH).
It is a randomized, prospective, single-blind study of two treatment techniques for rhizarthrosis. The patients are divided into two groups: one in which a Maia trapeziometacarpal prosthesis is implanted, and the other in which…
- Trial name
- NCT07101887
- Testing
- Implantation of thumb prosthesis, Burton-Pellegrini technique
- Where
- Spain
- Volunteers
- 61 people
- Sponsor
- Parc de Salut Mar