Clinical trials: Thumb Carpometacarpal Osteoarthritis
Thumb Osteoarthritis
Variable Immobilization Protocol for Arthroplasty of the Carpometacarpal Joint of the Thumb
Thumb carpometacarpal (CMC) osteoarthritis (OA) is common, seen frequently in middle-aged and elderly women. While a variety of surgical treatments have been described with none superior to any other, there is no consensus on the…
- Trial name
- NCT04828954
- Testing
- Immobilization for 2-weeks postoperative, Immobilization for 6-weeks postoperative
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Chicago
Thumb Carpometacarpal Joint Osteoarthritis
Biomechanical Evaluation With Finite Element Models in Thumb Carpometacarpal Osteoarthitis: Prospective Comparative Analysis of Loads in Arthroplasty With or Without Implants
To better understand the load distribution in the Thumb Carpometacarpal Joint (CMC joint) in presence of osteoarthritis and how surgery by means of a suspension-resection arthroplasty or a joint replacement by means of a metal…
- Trial name
- NCT07614269
- Testing
- Trapezectomy and carpometacarpal joint resection-supension arthroplasty, Trapeziometacarpal joint prosthesis
- Volunteers
- 40 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Osteoarthritis in the Carpometacarpal (CMC) Joint
CMC-1 Replacement Arthroplasty Versus Trapeziectomy
Thumb carpometacarpal (CMC-1) osteoarthritis is a common condition causing pain and disability, particularly among middle-aged and older women. When non-operative treatment fails, surgery is indicated.
- Trial name
- NCT07583628
- Volunteers
- 1,000 people
- Sponsor
- Karolinska Institutet
Trapeziometacarpal Osteoarthritis
FDI and APL Muscle Activation During Thumb Exercises in CMC Osteoarthritis
The aim of this study is to investigate whether there are differences in muscle activation of the First Dorsal Interosseous (FDI) and the Abductor Pollicis Longus (APL) between individuals with and without trapeziometacarpal…
- Trial name
- NCT07421089
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Malaga
Osteoarthrosis of the Carpometacarpal Joint of the Thumb
Postoperative Rehabilitation Following Trapeziectomy and Ligament Reconstruction Tendon Interposition
Carpometacarpal (CMC) arthritis of the thumb joint ('basal arthritis') is a common entity treated by hand surgeons in our society.
- Trial name
- LRTI (NCT01425034)
- Testing
- casts for the thumb, Motion group
- Where
- United States
- Volunteers
- 234 people
- Sponsor
- University of Utah
Osteoarthritis Thumb
Arthroscopic Debridement vs Arthroscopic Hemi-Trapeziectomy on Patients With Thumb Carpometacarpal Joint Osteoarthritis
Patients with thumb carpometacarpal joint osteoarthritis usually suffer from pain, joint enlargement, inflammation, deformity and loss of function.
- Trial name
- NCT04217928
- Testing
- Arthroscopic Debridement, Arthroscopic Hemi-Trapeziectomy with Mini TightRope
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- Chinese University of Hong Kong
Thumb Osteoarthritis, First Dorsal Interosseous Strengthening
Strengthening of the First Dorsal Interosseous for Thumb Carpometacarpal Osteoarthritis
To determine the effect of first dorsal interosseus (FDI) strengthening in patients with thumb carpometacarpal (CMC) osteoarthritis.
- Trial name
- NCT03177577
- Testing
- Splint, Splint with strengthening exercises
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Massachusetts General Hospital
Trapeziometacarpal Osteoarthritis
Thumb Proprioception in Trapeziometacarpal Osteoarthritis
This study looks at people who have osteoarthritis at the base of the thumb. It examines how well the thumb can sense its position and movement. The study has three goals: 1.
- Trial name
- NCT07447323
- Testing
- Thumb Proprioception Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Thumb Osteoarthritis, Hand Osteoarthritis
Evaluation of the Effects of High Intensity Laser Therapy and Exercise in Hand Thumb Osteoarthritis
One of the standard treatment methods in individuals with thumb osteoarthritis (OA) is exercise. Combination therapy options involving these exercises can be applied to patients.
- Trial name
- NCT07112742
- Testing
- High-Intensity Laser Therapy and Exercise, High-Intensity Laser Therapy at a Non-Therapeutic Dose Combined With Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- TC Erciyes University
Trapeziometacarpal Osteoarthritis, Thumb Carpometacarpal Osteoarthritis
Surgical Treatment for Trapeziometacarpal Osteoarthritis Eaton & Glickel Stage 2-3
Trapeziometacarpal osteoarthritis is a common cause of pain and loss of hand function in postmenopausal women. Many surgical treatments have been described and recent literature has show that the relatively simple trapeziectomy…
- Trial name
- NCT02204488
- Testing
- Total Joint Arthroplasty, Trapeziectomy
- Where
- Netherlands
- Volunteers
- 62 people
- Sponsor
- Isala
Thumb Osteoarthritis
Proprioceptive Thumb Exercises Program in Patients With Carpometacarpal Joint Osteoarthritis
Osteoarthritis (OA) is a chronic and prevalent joint disorder with great impact on quality of life and high economic burden. Although a number of conservative therapies have proven to be effective for the management of hand OA…
- Trial name
- thumb (NCT04738201)
- Testing
- Proprioceptive thumb exercises.
- Where
- Spain
- Volunteers
- 45 people
- Sponsor
- University of Malaga
Thumb Osteoarthritis
Ligament Reconstruction Weilby vs Simple Trapeziectomy
There is currently no consensus on the best surgical approach for carpometacarpal osteoarthritis treatment. Simple trapeziectomy (TI) or trapeziectomy with ligament reconstruction tendon interposition (LRTI) are both accepted…
- Trial name
- WEILBY (NCT03858946)
- Testing
- Simple trapeziectomy, Weilby
- Where
- 2 sites in Denmark
- Volunteers
- 60 people
- Sponsor
- University of Southern Denmark
Arthritis
Allograft Meniscal Arthroplasty for the Treatment of Basal Joint Arthritis of the Thumb
Hypothesis: The use of knee meniscal allograft as a joint spacer and stabilizer is a viable option for the surgical treatment of basal joint arthritis of the thumb.
- Trial name
- NCT01542515
- Testing
- Meniscal allograft arthroplasty of the carpometacarpal joint of the thumb
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Corewell Health East
Thumb Osteoarthritis, Pain
Laser Therapy, Pain and Carpometacarpal Joint Osteoarthritis Treatment
Osteoarthritis (OA) is a chronic and prevalent joint disorder with great impact on quality of life and high economic burden. Although a number of conservative therapies have proven to be effective for the management of hand OA…
- Conditions
- Thumb Osteoarthritis, Pain, Physical Disorder
- Trial name
- Laser (NCT03270488)
- Testing
- Laser
- Where
- Spain
- Volunteers
- 61 people
- Sponsor
- University of Malaga
Thumb Osteoarthritis
Trapeziometacarpal Joint Arthroplasty Versus Trapeziectomy for Thumb Carpometacarpal Osteoarthritis
Thumb carpometacarpal osteoarthritis is common and may cause severe pain and functional limitation. Trapeziectomy is widely used, whereas prosthetic arthroplasty may offer faster early recovery.
- Trial name
- T3 (NCT07552831)
- Testing
- trapeziometacarpal arthroplasty, Trapeziectomy
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Sahlgrenska University Hospital
Thumb Osteoarthritis
Influence of Custom Orthosis Post Carpometacarpal (CMC) Arthroplasty
This study aims to compare post-surgical outcomes of individuals who receive either a custom orthosis or prefabricated splint after carpometacarpal arthroplasty.
- Trial name
- NCT05307510
- Testing
- Prefabricated splint, Custom Orthosis
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Toledo
Osteoarthritis Thumb, Joint Diseases
Touch on One Thumb, RSI on the Other Thumb: Which Surgery Shows Better Results
The study aims to determine whether CMC I arthroplasty using a Touch® implant results in higher patient satisfaction compared to RSI arthroplasty in the medium-term in patients with primary thumb osteoarthritis.
- Conditions
- Osteoarthritis Thumb, Joint Diseases, Musculoskeletal Diseases or Conditions, Osteoarthritis
- Trial name
- NCT05849506
- Testing
- Touch® Prosthesis
- Where
- Switzerland
- Volunteers
- 14 people
- Sponsor
- Schulthess Klinik
Osteoarthrosis of the Carpometacarpal Joint of the Thumb
Study on Basal Joint Arthritis Prospective
The data in this prospective registry will be used 1) to define which surgical and nonoperative techniques are most effective at providing pain relief, restoring function, are cost effective, and patients are satisfied with their…
- Trial name
- NCT01376024
- Where
- 3 sites in United States
- Volunteers
- 800 people
- Sponsor
- Columbia University
Osteoarthritis Thumb
The Effects of Two Different Orthosis on Pain, Hand Strength and Function in Patients With Thumb Carpometacarpal Osteoarthritis
The investigators aimed to assess the effects of two different hand orthosis on hand functioning, pain, disability and quality of life in patients with thumb osteoarthritis
- Trial name
- NCT03327480
- Testing
- orthosis
- Volunteers
- 60 people
- Sponsor
- Diskapi Teaching and Research Hospital
Arthritis Multiple Joint
Botulism Toxin Injection as a Treatment for Arthritis of the Basal Thumb Joint
Basal arthritis of the thumb is a common condition with increased prevalence in post-menopausal women, obese persons, and the elderly. Surgical options are varied and efficacious, but not all patients are candidates for surgery.
- Trial name
- NCT01045694
- Testing
- Botulinum Toxin Type A, Steroid - Triamcinolone Acetonide, Lidocaine
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Missouri-Columbia