Clinical trials: Thumb Osteoarthritis
Osteoarthritis Thumb
Single Blinded First CMC Osteoarthritis Treatment
Single blinded PRP vs. Corticosteroid vs. Placebo (normal saline) intra-articular injection for basal joint arthritis.
- Trial name
- NCT03196310
- Testing
- Platelet Concentrate, Corticosteroid injection, Normal Saline
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Kettering Health Network
Thumb Osteoarthritis, Hand Osteoarthritis
Evaluation of the Effects of High Intensity Laser Therapy and Exercise in Hand Thumb Osteoarthritis
One of the standard treatment methods in individuals with thumb osteoarthritis (OA) is exercise. Combination therapy options involving these exercises can be applied to patients.
- Trial name
- NCT07112742
- Testing
- High-Intensity Laser Therapy and Exercise, High-Intensity Laser Therapy at a Non-Therapeutic Dose Combined With Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- TC Erciyes University
Thumb Osteoarthritis
NSAID Injection Versus Corticosteroid Injection for Basilar Thumb Arthritis
The Researchers are trying to compare two different types of intraarticular injections (injection in the joint) for treating the symptoms of moderate to advanced basilar thumb arthritis.
- Trial name
- NCT05992883
- Testing
- Ketorolac, Triamcinolone
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Mayo Clinic
Trapeziometacarpal Osteoarthritis, Thumb Carpometacarpal Osteoarthritis
Surgical Treatment for Trapeziometacarpal Osteoarthritis Eaton & Glickel Stage 2-3
Trapeziometacarpal osteoarthritis is a common cause of pain and loss of hand function in postmenopausal women. Many surgical treatments have been described and recent literature has show that the relatively simple trapeziectomy…
- Trial name
- NCT02204488
- Testing
- Total Joint Arthroplasty, Trapeziectomy
- Where
- Netherlands
- Volunteers
- 62 people
- Sponsor
- Isala
Thumb Osteoarthritis, Hand Injuries
High-Energy Laser in the Conservative Treatment of Rhizarthrosis
Osteoarthritis (OA) is a degenerative joint disease that can affect the hands and is particularly debilitating when it involves the trapeziometacarpal joint (rhizarthrosis).
- Conditions
- Thumb Osteoarthritis, Hand Injuries, Laser, Exercise
- Trial name
- HLEX-TO (NCT07566507)
- Testing
- THEAL:Ixyon XP (Mectronic, Bergamo, Italy)
- Where
- Italy
- Volunteers
- 42 people
- Sponsor
- Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
Thumb Osteoarthritis
Proprioceptive Thumb Exercises Program in Patients With Carpometacarpal Joint Osteoarthritis
Osteoarthritis (OA) is a chronic and prevalent joint disorder with great impact on quality of life and high economic burden. Although a number of conservative therapies have proven to be effective for the management of hand OA…
- Trial name
- thumb (NCT04738201)
- Testing
- Proprioceptive thumb exercises.
- Where
- Spain
- Volunteers
- 45 people
- Sponsor
- University of Malaga
Thumb Osteoarthritis, Thumb Injury
Validity And Reliability of the Turkish Version of the Thumb Disability Examination
Purpose of the study is the validity and reliability of the Turkish version of The Thumb Disability Examination (TDX) so that it would be used as an assessment tool for Turkish thumb patients.
- Conditions
- Thumb Osteoarthritis, Thumb Injury, Thumb Fracture, Thumb Laceration
- Trial name
- NCT04627259
- Testing
- Thumb Disability Examination
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Hacettepe University
Thumb Osteoarthritis
Ligament Reconstruction Weilby vs Simple Trapeziectomy
There is currently no consensus on the best surgical approach for carpometacarpal osteoarthritis treatment. Simple trapeziectomy (TI) or trapeziectomy with ligament reconstruction tendon interposition (LRTI) are both accepted…
- Trial name
- WEILBY (NCT03858946)
- Testing
- Simple trapeziectomy, Weilby
- Where
- 2 sites in Denmark
- Volunteers
- 60 people
- Sponsor
- University of Southern Denmark
Osteoarthritis Finger, Osteoarthritis Thumb
Prospective Study of Arthrodesis of Finger Distal Interphalangeal Joints Using the Kerifuse Device
Arthrodesis of a distal interphalangeal joint of the finger (DIP) is mainly performed for a degenerated and painful joint. Various stabilization methods have been used to provide compression at the arthrodesis site such as pins…
- Trial name
- KF23 (NCT06151834)
- Testing
- KeriFuse implant implantation
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Clinique Saint François, Nice, France
Arthritis
Allograft Meniscal Arthroplasty for the Treatment of Basal Joint Arthritis of the Thumb
Hypothesis: The use of knee meniscal allograft as a joint spacer and stabilizer is a viable option for the surgical treatment of basal joint arthritis of the thumb.
- Trial name
- NCT01542515
- Testing
- Meniscal allograft arthroplasty of the carpometacarpal joint of the thumb
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Corewell Health East
Thumb Osteoarthritis, Pain
Laser Therapy, Pain and Carpometacarpal Joint Osteoarthritis Treatment
Osteoarthritis (OA) is a chronic and prevalent joint disorder with great impact on quality of life and high economic burden. Although a number of conservative therapies have proven to be effective for the management of hand OA…
- Conditions
- Thumb Osteoarthritis, Pain, Physical Disorder
- Trial name
- Laser (NCT03270488)
- Testing
- Laser
- Where
- Spain
- Volunteers
- 61 people
- Sponsor
- University of Malaga
Osteoarthritis Thumbs, Rhizarthrosis
Pinch Grip and Functional Outcomes Between Hematoma Distraction Arthroplasty Versus Ligament Reconstruction Tendon Interposition Arthroplasty in Trapeziometacarpal Osteoarthritis.
To date, there is no gold standard for the treatment of severe trapeziometacarpal joint osteoarthritis. Despite the fact that new procedures have been described, techniques such hematoma distraction or ligament reconstruction…
- Conditions
- Osteoarthritis Thumbs, Rhizarthrosis, Trapeziometacarpal (TMC) Arthrosis
- Trial name
- Rhizarthrosis (NCT06858800)
- Testing
- LTRI technique, HDA technique
- Where
- Spain
- Volunteers
- 96 people
- Sponsor
- Hospital de la Santa creu i Sant Pau - Barcelona
Thumb Osteoarthritis
Trapeziometacarpal Joint Arthroplasty Versus Trapeziectomy for Thumb Carpometacarpal Osteoarthritis
Thumb carpometacarpal osteoarthritis is common and may cause severe pain and functional limitation. Trapeziectomy is widely used, whereas prosthetic arthroplasty may offer faster early recovery.
- Trial name
- T3 (NCT07552831)
- Testing
- trapeziometacarpal arthroplasty, Trapeziectomy
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Sahlgrenska University Hospital
Thumb Osteoarthritis
Influence of Custom Orthosis Post Carpometacarpal (CMC) Arthroplasty
This study aims to compare post-surgical outcomes of individuals who receive either a custom orthosis or prefabricated splint after carpometacarpal arthroplasty.
- Trial name
- NCT05307510
- Testing
- Prefabricated splint, Custom Orthosis
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Toledo
Thumb Osteoarthritis
Postoperative Therapy After Interposition Arthroplasty in CMC1
In this randomized controlled trial the investigators want to investigate whether early versus late mobilisation after surgery in the first carpometacarpal joint (CMC1) leads to a faster recovery of hand function.
- Trial name
- NCT01679717
- Testing
- Early mobilisation after CMC1-surgery
- Where
- Norway
- Volunteers
- 70 people
- Sponsor
- Diakonhjemmet Hospital
Rizarthrosis
Comparative Study Between the Use of Trapeziometacarpal Prostheses and the Usual Resection-tenosuspension Arthroplasty for the Treatment of Rhizarthrosis, Focusing on Changes in Pain (Measured With the VAS Scale) and Function (With the Quick-DASH).
It is a randomized, prospective, single-blind study of two treatment techniques for rhizarthrosis. The patients are divided into two groups: one in which a Maia trapeziometacarpal prosthesis is implanted, and the other in which…
- Trial name
- NCT07101887
- Testing
- Implantation of thumb prosthesis, Burton-Pellegrini technique
- Where
- Spain
- Volunteers
- 61 people
- Sponsor
- Parc de Salut Mar
Osteoarthritis Thumb, Joint Diseases
Touch on One Thumb, RSI on the Other Thumb: Which Surgery Shows Better Results
The study aims to determine whether CMC I arthroplasty using a Touch® implant results in higher patient satisfaction compared to RSI arthroplasty in the medium-term in patients with primary thumb osteoarthritis.
- Conditions
- Osteoarthritis Thumb, Joint Diseases, Musculoskeletal Diseases or Conditions, Osteoarthritis
- Trial name
- NCT05849506
- Testing
- Touch® Prosthesis
- Where
- Switzerland
- Volunteers
- 14 people
- Sponsor
- Schulthess Klinik
Osteoarthrosis of the Carpometacarpal Joint of the Thumb
Study on Basal Joint Arthritis Prospective
The data in this prospective registry will be used 1) to define which surgical and nonoperative techniques are most effective at providing pain relief, restoring function, are cost effective, and patients are satisfied with their…
- Trial name
- NCT01376024
- Where
- 3 sites in United States
- Volunteers
- 800 people
- Sponsor
- Columbia University
Osteoarthritis of the CMC-1 Joint
TRACE - Thumb Base Replacement Arthroplasty for Osteoarthritis.
Osteoarthritis in the base of the thumb is one of the most common forms of hand arthritis. It usually appears in middle age, particularly in women, and can cause significant pain and loss of function.
- Trial name
- TRACE (NCT07178223)
- Testing
- Arthroplasty CMC-1
- Where
- Sweden
- Volunteers
- 90 people
- Sponsor
- Karolinska Institutet
Thumb Osteoarthritis
Trapeziectomy vs. Trapeziometacarpal Limited Excision for Thumb Base Osteoarthritis
A randomized comparison between trapeziectomy and trapeziometacarpal limited excision for thumb base osteoarthritis in 90 patients.
- Trial name
- NCT04210687
- Testing
- trapeziometacarpal limited excision, Trapeziectomy
- Where
- Sweden
- Volunteers
- 90 people
- Sponsor
- Karolinska Institutet