Clinical trials: Thumb Osteoarthritis
Osteoarthritis Thumb
The Effects of Two Different Orthosis on Pain, Hand Strength and Function in Patients With Thumb Carpometacarpal Osteoarthritis
The investigators aimed to assess the effects of two different hand orthosis on hand functioning, pain, disability and quality of life in patients with thumb osteoarthritis
- Trial name
- NCT03327480
- Testing
- orthosis
- Volunteers
- 60 people
- Sponsor
- Diskapi Teaching and Research Hospital
Arthritis Multiple Joint
Botulism Toxin Injection as a Treatment for Arthritis of the Basal Thumb Joint
Basal arthritis of the thumb is a common condition with increased prevalence in post-menopausal women, obese persons, and the elderly. Surgical options are varied and efficacious, but not all patients are candidates for surgery.
- Trial name
- NCT01045694
- Testing
- Botulinum Toxin Type A, Steroid - Triamcinolone Acetonide, Lidocaine
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Missouri-Columbia
Arthritis, Health Related Quality of Life
A Case Series Comparing T+LRTI to Partial Trapeziectomy for Thumb Osteoarthritis
The purpose of this study was to measure the differences in Health Related Quality of Life (HRQOL) and functional measurements between two groups of patients with Carpometacarpal Osteoarthritis of the thumb.
- Conditions
- Arthritis, Health Related Quality of Life, Osteoarthritis
- Trial name
- NCT03392454
- Testing
- T+LRTI, PT+TI
- Volunteers
- 20 people
- Sponsor
- McMaster University
Carpometacarpal Osteoarthritis, Rhizarthrosis
Trapeziectomy Suspensionplasty Versus Carpometacarpal Joint Replacement in Treatment of Basal Thumb Osteoarthritis
This study compares and evaluates differences in movement analysis, patient-reported outcome, radiological assesment and muscular function between patients undergoing carpometacarpal joint arthroplasty with use of modern implants…
- Conditions
- Carpometacarpal Osteoarthritis, Rhizarthrosis, Thumb Osteoarthritis
- Trial name
- NCT04588961
- Testing
- Trapeziectomy with suspensionplasty, Joint alloplasty
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Medical University of Warsaw
Trapeziometacarpal Osteoarthritis
Corticosteroid Against Saline Injections for Thumb Osteoarthritis (CASITOA)
Thumb osteoarthritis or trapeziometacarpal osteoarthritis (TMO) is a common and painful form of hand arthritis that limits thumb mobility and hand function, affecting patients' quality of life.
- Trial name
- CASITOA (NCT06401317)
- Testing
- Saline Solution (NaCl 0,9%), Triamcinolone Acetonide
- Where
- 2 sites in Canada
- Volunteers
- 40 people
- Sponsor
- Université du Québec à Trois-Rivières
Osteoarthritis of the Hand
AP-011 Study to Evaluate the Safety of a Single Intra-articular Injection of Ampion™ for Arthritis of the Basal Thumb Joint
This study will evaluate the safety of an intra-articular injection of AMPION™ in adults with pain due to osteoarthritis of the basal thumb joint.
- Trial name
- NCT02762760
- Testing
- AMPION™, Saline
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Ampio Pharmaceuticals. Inc.
Osteoarthritis Thumb
Intraarticular Steroids, Saline and Occupational Therapy in People With CMC1 Osteoarthritis
A placebo-controlled randomized controlled trial exploring the effect of intraarticular steroids, saline or an occupational therapy intervention in inflammatory carpometacarpal-1 osteoarthritis
- Trial name
- PICASSO (NCT06084364)
- Testing
- Injection of triamcinolone acetonide into the CMC-1 joint, Multimodal Occupational therapy for CMC-1 joint OA
- Where
- 6 sites in Norway
- Volunteers
- 354 people
- Sponsor
- Diakonhjemmet Hospital
Chronic Pain, Osteoarthritis, Knee
Embo Registry; National Registry for Artery Embolization
Embo Registry is a retrospective and prospective observational study to evaluate real world effectiveness and the use of Artery Embolization as a treatment for chronic pain with patients that have osteoarthritis and localized…
- Conditions
- Chronic Pain, Osteoarthritis, Knee, Osteoarthritis Thumb, Osteoarthritis Shoulder
- Trial name
- NCT06477965
- Testing
- Artery Embolization
- Where
- 2 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Vascular Solutions of North Carolina
Osteoarthritis Thumb
Post Market Clinical Follow-Up TOUCH® CMC 1
Because severe pain, weakened pinch and grip strength produce functional disabilities, the basal joint of the thumb is the most common site of surgical reconstruction in the upper limb due to OA.
- Trial name
- NCT06546306
- Testing
- TOUCH® CMC 1
- Where
- 6 sites in France
- Volunteers
- 216 people
- Sponsor
- Keri Medical SA
Rhizarthrosis
Dual Mobility Total Joint Prosthesis (Touch) for Thumb Carpometacarpal Joint Osteoarthritis
The dual mobility concept currently represents the newest generation of thumb carpometacarpal prostheses. The aim of this study was to evaluate the outcomes of TOUCH® prosthesis.
- Trial name
- NCT05047744
- Testing
- Touch Dual Mobility CMC I Prosthesis
- Where
- Austria
- Volunteers
- 100 people
- Sponsor
- Kepler University Hospital
Carpometacarpal Osteoarthritis
Effect of Perioperative Acetaminophen Dosing on Patients Undergoing Surgical Treatment of Basilar Thumb Arthritis
Basilar thumb arthritis is a common problem that affects 7% of men and 15% of women. It is regarded as one of the more painful procedures commonly performed by hand surgeons.
- Trial name
- NCT05556356
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Indiana Hand to Shoulder Center
Thumb Osteoarthritis
Thumb Base Osteoarthritis: Ultrasound-guided Platelet-rich Plasma Versus Placebo Injection
The goal of this clinical trial is to evaluate whether platelet-rich plasma (PRP) injections improve pain and function in adults with thumb base osteoarthritis (CMC-I OA).
- Trial name
- Thumbs-up (NCT07491302)
- Testing
- Platelet-Rich Plasma (PRP) Injections, Saline (0.9% NaCl)
- Where
- Netherlands
- Volunteers
- 88 people
- Sponsor
- Goed Medisch Centrum
Osteoarthrosis, Ultrasound
Ultrasound Findings of Thumb Muscles in 1st Carpometacarpal Osteoarthritis
Carpometacarpal (CMC) joint osteoarthritis is a disorder that is estimated to affect more than one-third of postmenopausal women, leading to decreased muscle strength, reduced joint range of motion, and pain.The pathogenesis of…
- Trial name
- NCT06600464
- Testing
- Ultrasound, Assessment of Muscle Strength in Both Hands, Assessment of Pain Threshold
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Thumb Carpometacarpal Joint Osteoarthritis
Platelet-rich Plasma for Thumb Carpometacarpal Joint Osteoarthritis
The purpose of this study is to investigate a case series of patients treated with Platelet-rich plasma for thumb carpometacarpal joint osteoarthritis.
- Trial name
- NCT04886349
- Testing
- Platelet-rich plasma
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- Mayo Clinic
Osteoarthritis
A Prospective Randomized Trial Comparing Standard Ligament Reconstruction Tendon Interposition (LRTI) VS Ligament Reconstruction Tendon Interposition (LRTI) With an Interference Screw for Thumb Carpometacarpal Arthritis - Pilot Study
A Prospective Randomized Trial Comparing Standard Ligament Reconstruction Tendon Interposition (LRTI) VS Ligament Reconstruction Tendon Interposition (LRTI) with an interference screw for thumb carpometacarpal arthritis
- Trial name
- NCT02352610
- Testing
- LRTI, Biotenodesis Screw
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Andrew Trenholm
Carpometacarpal Osteoarthritis
Thumb Osteoarthritis: A Cross-Sectional Study of Mechanisms
This study examines carpometacarpal osteoarthritis (CMC OA) and aims to elucidate the biomechanical, neuromuscular, and somatosensory mechanisms that contribute to CMC OA symptoms by using orthopaedic biomechanics and…
- Trial name
- NCT04104477
- Testing
- Range of Motion Tasks, Strength Tasks
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Florida
Complications Due to Internal Joint Prosthesis, Thumb Osteoarthritis
Study of the Touch® Trapezo-metacarpal Prosthesis
Prospective observational study of implanted patients with a new orthopaedic implant: the Touch trapezo-metacarpal prosthesis
- Trial name
- NCT03611023
- Where
- France
- Volunteers
- 350 people
- Sponsor
- Groupe Concepteur Touch
Trapeziometacarpal Osteoarthritis
Thumb Muscle Activation During Different Activities of Daily Living in Thumb Base Osteoarthritis and Healthy Controls
The aim of this study is to investigate whether there are differences in muscle activation of the first dorsal interosseous (FDI) and the abductor pollicis longus (APL) between individuals with and without thumb…
- Trial name
- NCT07866703
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Malaga
Osteoarthritis
CMC (Carpometacarpal) OA (Osteoarthritis) Thumb Splint Study
Osteoarthritis (OA) of the thumb carpometacarpal (CMC) joint is a common condition that is seen regularly in outpatient occupational therapy and physiotherapy departments.
- Trial name
- NCT00705146
- Testing
- Comfort Cool thumb splint by North Coast Medical, Custom made thermoplastic & neoprene splint
- Where
- 3 sites in Canada
- Volunteers
- 56 people
- Sponsor
- University of British Columbia
Thumb Osteoarthritis
Arthroscopic Resection Arthroplasty of Carpometacarpal and/or Pantrapezial Osteoarthritis
Compare outcomes of ARA for isolated CMC OA versus to simultaneous ARA of CMC plus STT
- Trial name
- ARA:BJA-OA (NCT02958137)
- Testing
- Arthroscopic Resection Arthroplasty
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Orthopaedic Specialist, PC, Davenport, IA