Clinical trials: Thumb Osteoarthritis
Osteoarthritis Thumb
Post Market Clinical Follow-Up TOUCH® CMC 1
Because severe pain, weakened pinch and grip strength produce functional disabilities, the basal joint of the thumb is the most common site of surgical reconstruction in the upper limb due to OA.
- Trial name
- NCT06546306
- Testing
- TOUCH® CMC 1
- Where
- 6 sites in France
- Volunteers
- 216 people
- Sponsor
- Keri Medical SA
Osteoarthritis Thumb
A Study on the Effect of High-concentrated Platelet Rich Plasma (PRP) on Osteoarthritis in the Thumb Base.
This is a randomized double-blinded randomized comparison between injection of platelet rich plasma (PRP) and placebo for thumb basale osteoarthritis.
- Trial name
- NCT06193499
- Testing
- Platelet rich plasma (PRP)
- Where
- Sweden
- Volunteers
- 90 people
- Sponsor
- Karolinska Institutet
Thumb Osteoarthritis
Turmeric for Patients With Basal Joint Arthritis
The aim of this study is to assess whether the use of a commercially available nutraceutical, turmeric, is an effective option to manage pain and stiffness in patients with basal joint arthritis.
- Trial name
- NCT03017118
- Testing
- Turmeric
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
Base-of-thumb Osteoarthritis, Osteoarthritis
Efficacy of Two Ultrasound-guided Intra-articular Injections of Botox® Combined With Custom-made Rigid Splinting in Painful Base-of-thumb Osteoarthritis.
The main objective of this study will be to compare the effects of 2 intra-articular injections of onabotulinumtoxinA with those of 1 intra-articular injection of onabotulinumtoxinA and 1 of normal saline and those of 2…
- Trial name
- RHIBOTII (NCT06902805)
- Testing
- OnabotulinumtoxinA
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Trapeziometacarpal Osteoarthritis
Thumb Muscle Activation During Different Activities of Daily Living in Thumb Base Osteoarthritis and Healthy Controls
The aim of this study is to investigate whether there are differences in muscle activation of the first dorsal interosseous (FDI) and the abductor pollicis longus (APL) between individuals with and without thumb…
- Trial name
- NCT07866703
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Malaga
Thumb Osteoarthritis
Arthroscopic Resection Arthroplasty of Carpometacarpal and/or Pantrapezial Osteoarthritis
Compare outcomes of ARA for isolated CMC OA versus to simultaneous ARA of CMC plus STT
- Trial name
- ARA:BJA-OA (NCT02958137)
- Testing
- Arthroscopic Resection Arthroplasty
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Orthopaedic Specialist, PC, Davenport, IA
Osteoarthrosis of the Carpometacarpal Joint of the Thumb
Postoperative Rehabilitation Following Trapeziectomy and Ligament Reconstruction Tendon Interposition
Carpometacarpal (CMC) arthritis of the thumb joint ('basal arthritis') is a common entity treated by hand surgeons in our society.
- Trial name
- LRTI (NCT01425034)
- Testing
- casts for the thumb, Motion group
- Where
- United States
- Volunteers
- 234 people
- Sponsor
- University of Utah
Carpometacarpal (CMC) Joint Arthritis
Oval-8 Splinting Versus Standardized Treatment With Tee Pee or Forearm Based Thumb Spica Splinting
The oval-8 splint has been developed for many uses in finger pathology and trauma. It has not, however, been used to treat thumb carpometacarpal (CMC) joint arthritis.
- Trial name
- Oval-8 (NCT02266095)
- Testing
- Oval-8 Splint, Tee Pee Splint, Forearm Based Splint
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Trapeziometacarpal Osteoarthritis, Thumb Carpometacarpal Osteoarthritis
Surgical Treatment for Trapeziometacarpal Osteoarthritis Eaton & Glickel Stage 2-3
Trapeziometacarpal osteoarthritis is a common cause of pain and loss of hand function in postmenopausal women. Many surgical treatments have been described and recent literature has show that the relatively simple trapeziectomy…
- Trial name
- NCT02204488
- Testing
- Total Joint Arthroplasty, Trapeziectomy
- Where
- Netherlands
- Volunteers
- 62 people
- Sponsor
- Isala
Flexor Tendon Rupture, Thumb Osteoarthritis
Occupational Therapy Pre-operative Education in the Orthopedic Hand Setting
This will be a prospective randomized control trial with a blocking method to determine the effect of an occupational therapy focused pre-operative education on 3 pre-determined diagnosis: Carpometacarpal (CMC) Arthroplasty…
- Conditions
- Flexor Tendon Rupture, Thumb Osteoarthritis, Distal Radius Fracture
- Trial name
- NCT05095415
- Testing
- Occupational Therapy Pre-operative Consult, Typical Pre-Operative Education
- Sponsor
- Methodist University, North Carolina
Arthritis
Allograft Meniscal Arthroplasty for the Treatment of Basal Joint Arthritis of the Thumb
Hypothesis: The use of knee meniscal allograft as a joint spacer and stabilizer is a viable option for the surgical treatment of basal joint arthritis of the thumb.
- Trial name
- NCT01542515
- Testing
- Meniscal allograft arthroplasty of the carpometacarpal joint of the thumb
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Corewell Health East
Thumb Osteoarthritis
Trapeziectomy vs. Trapeziometacarpal Limited Excision for Thumb Base Osteoarthritis
A randomized comparison between trapeziectomy and trapeziometacarpal limited excision for thumb base osteoarthritis in 90 patients.
- Trial name
- NCT04210687
- Testing
- trapeziometacarpal limited excision, Trapeziectomy
- Where
- Sweden
- Volunteers
- 90 people
- Sponsor
- Karolinska Institutet
Thumb Carpometacarpal Joint Osteoarthritis
Biomechanical Evaluation With Finite Element Models in Thumb Carpometacarpal Osteoarthitis: Prospective Comparative Analysis of Loads in Arthroplasty With or Without Implants
To better understand the load distribution in the Thumb Carpometacarpal Joint (CMC joint) in presence of osteoarthritis and how surgery by means of a suspension-resection arthroplasty or a joint replacement by means of a metal…
- Trial name
- NCT07614269
- Testing
- Trapezectomy and carpometacarpal joint resection-supension arthroplasty, Trapeziometacarpal joint prosthesis
- Volunteers
- 40 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Thumb Osteoarthritis
Distraction vs Interposition Arthroplasty for Basilar Thumb Osteoarthritis
Surgical management for osteoarthritis of the thumb is indicated when conservative measures have failed, and numerous techniques have been proposed.
- Trial name
- NCT04155853
- Testing
- Interposition Arthroplasty, Hematoma and Distraction Arthroplasty
- Where
- Greece
- Volunteers
- 22 people
- Sponsor
- Aristotle University Of Thessaloniki
Thumb Osteoarthritis
Ligament Reconstruction Weilby vs Simple Trapeziectomy
There is currently no consensus on the best surgical approach for carpometacarpal osteoarthritis treatment. Simple trapeziectomy (TI) or trapeziectomy with ligament reconstruction tendon interposition (LRTI) are both accepted…
- Trial name
- WEILBY (NCT03858946)
- Testing
- Simple trapeziectomy, Weilby
- Where
- 2 sites in Denmark
- Volunteers
- 60 people
- Sponsor
- University of Southern Denmark
Osteoarthritis Thumb
Comparison of the Efficacy of Intra-articular Hybrid Hyaluronic Acid and Steroid in Patients With Rizoarthrosis
Osteoarthritis of the trapeziometacarpal joint (TMJ), also called rhizarthrosis is a common disease, mostly affecting post-menopausal women.
- Trial name
- NCT03200886
- Testing
- Sinovial H-L, Triamcinolone Acetonide
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Siena
Osteoarthritis
Use of Autologous Adipose-Derived Stromal Vascular Fraction To Treat Osteoarthritis of Hip, Knee, Ankle, and Thumb Joints
This study will examine the safety and efficacy of autologous adipose-derived stromal vascular fraction (SVF) cells for treatment of hip, knee and thumb osteoarthritis (OA); monitoring adverse events and measuring pain, function…
- Trial name
- NCT03166410
- Testing
- Cell injection
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Texas Plastic Surgery
Thumb Osteoarthritis, Thumb Carpometacarpal Joint Osteoarthritis
Surgery for Thumb Base Osteoarthritis: Joint Replacement vs. Trapeziectomy
The goal of this clinical trial is to learn if the surgical method with total joint arthroplasty, (TOUCH joint prosthesis), is as good as or better than the traditional surgical method, trapezectomy, to treat thumb base joint…
- Conditions
- Thumb Osteoarthritis, Thumb Carpometacarpal Joint Osteoarthritis, Carpometacarpal (CMC) Joint Arthritis, Basal Thumb Osteoartrithis
- Trial name
- BASTION (NCT07569549)
- Testing
- Implantation of trapeziometacarpal prosthesis, Trapeziectomy with Capsuloplasty
- Where
- Sweden
- Volunteers
- 84 people
- Sponsor
- Uppsala University
Chronic Pain, Osteoarthritis, Knee
Embo Registry; National Registry for Artery Embolization
Embo Registry is a retrospective and prospective observational study to evaluate real world effectiveness and the use of Artery Embolization as a treatment for chronic pain with patients that have osteoarthritis and localized…
- Conditions
- Chronic Pain, Osteoarthritis, Knee, Osteoarthritis Thumb, Osteoarthritis Shoulder
- Trial name
- NCT06477965
- Testing
- Artery Embolization
- Where
- 2 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Vascular Solutions of North Carolina
CBD, Hand Osteoarthritis
Is Topical CBD Effective in Treating Thumb Joint Arthritis
Rationale: CBD is commonly being used as an over-the-counter treatment for arthritis-related pain, however no clinical trial has been performed to establish efficacy.
- Trial name
- NCT04611347
- Testing
- CBD, Shea Butter
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Virginia