Clinical trials: Thumb Osteoarthritis
Arthritis of Carpometacarpal Joint of Left Thumb, Arthritis of Carpometacarpal Joint of Right Thumb
Oral Curcumin for the Treatment of Pain of Thumb Base Joint (CMC) Arthritis
The goal of this clinical trial is to learn about the use of turmeric (Curcumin) as a treatment for pain of thumb-joint arthritis. Turmeric is commonly being used as an over-the-counter treatment for musculoskeletal pain.
- Trial name
- NCT06359665
- Testing
- Curcumin
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Brent DeGeorge
Osteoarthritis Thumb, Joint Diseases
Radial Nerve Mobilization in Hand Thumb Osteoarthritis Patients
Hand-thumb carpometacarpal (1st CMC) joint osteoarthritis is defined as the degeneration occurring between the articular surfaces of the 1st metacarpal bone and the trapezium bone.
- Conditions
- Osteoarthritis Thumb, Joint Diseases, Radial Neuropathy
- Trial name
- NCT05650970
- Testing
- routine therapy, radial nerve mobilization exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Gazi University
Osteoarthritis
Safety Study of Thumb Orthoses in Osteoarthritis in the Base of the Thumb (BTOA)
The prevalence of digital osteoarthritis varies according to whether a radiological or clinical definition is adopted. Interventions: Thumb orthoses to be worn at night and usual care vs usual care.
- Trial name
- NCT00350896
- Testing
- Thumb orthoses
- Volunteers
- 120 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Thumb Osteoarthritis
Pulsed Electromagnetic Field (PEMF) Therapy in Thumb CMC Arthritis
Long-Term Objective: Determine if high-frequency PEMF therapy reduces pain in patients with thumb carpometacarpal (CMC) joint osteoarthritis (OA).
- Trial name
- NCT05315297
- Testing
- PEMF device
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Stanford University
Thumb Osteoarthritis
A Study on the Effect of Platelet Rich Plasma (PRP) on Osteoarthritis in the Thumb Base
Randomized comparison between Platelet Rich Plasma (PRP) and placebo (Saline) for thumb base.osteoarthritis.
- Trial name
- NCT04218591
- Testing
- PRP
- Where
- Sweden
- Volunteers
- 90 people
- Sponsor
- Karolinska Institutet
Flexor Tendon Rupture, Thumb Osteoarthritis
Occupational Therapy Pre-operative Education in the Orthopedic Hand Setting
This will be a prospective randomized control trial with a blocking method to determine the effect of an occupational therapy focused pre-operative education on 3 pre-determined diagnosis: Carpometacarpal (CMC) Arthroplasty…
- Conditions
- Flexor Tendon Rupture, Thumb Osteoarthritis, Distal Radius Fracture
- Trial name
- NCT05095415
- Testing
- Occupational Therapy Pre-operative Consult, Typical Pre-Operative Education
- Sponsor
- Methodist University, North Carolina
Carpometacarpal Osteoarthritis
An Open Label Trial for Treating Carpometacarpal Osteoarthritis of the Thumb: Pilot Study
The purpose of this study is to find out if hyaluronan, an injectable medication for knee arthritis, also works for arthritis at the base of the thumb.
- Trial name
- NCT00198029
- Testing
- Synvisc (hylan G-F20)
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Hospital for Special Surgery, New York
Thumb Osteoarthritis
Anatomical Evaluation of the APL Tendons in Thumb CMC Joint and Osteoarthritis
Certain ligaments in the human body are designed to be a static stabilizer and others to have a sensory function thus remains an unresolved issue.
- Trial name
- NCT05626192
- Testing
- Anatomical dissection and Immunohistochemical techniques
- Where
- 2 sites in Spain
- Volunteers
- 20 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Osteoarthritis Thumb
Influence of the Radiological Stage on the Efficiency of Viscosupplementation in Basal Thumb Arthritis
The rhizarthrose is the most frequent affection of the hand at the age fifty and beyond. For the moderate forms of the disease, the majority of the studies recommend the recourse to the viscosupplement because of its efficiency…
- Trial name
- INSTINCT (NCT03622736)
- Where
- France
- Volunteers
- 122 people
- Sponsor
- Labrha
Carpal Tunnel Syndrome, Osteoarthritis Thumb
Concomitant Basal Joint Arthroplasty and Carpal Tunnel Release
Concomitant carpal tunnel syndrome and basal thumb junt osteoarthritis through a single incision has been described. Case serials have reported good with this technique.
- Trial name
- NCT04391751
- Testing
- Carpal tunnel release and basal joint arthroplasty through single incision, Carpal tunnel release and basal joint arthroplasty through double incision
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Thumb Osteoarthritis
Arthroscopic Resection Arthroplasty of Carpometacarpal and/or Pantrapezial Osteoarthritis
Compare outcomes of ARA for isolated CMC OA versus to simultaneous ARA of CMC plus STT
- Trial name
- ARA:BJA-OA (NCT02958137)
- Testing
- Arthroscopic Resection Arthroplasty
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Orthopaedic Specialist, PC, Davenport, IA
Osteoarthritis
CMC (Carpometacarpal) OA (Osteoarthritis) Thumb Splint Study
Osteoarthritis (OA) of the thumb carpometacarpal (CMC) joint is a common condition that is seen regularly in outpatient occupational therapy and physiotherapy departments.
- Trial name
- NCT00705146
- Testing
- Comfort Cool thumb splint by North Coast Medical, Custom made thermoplastic & neoprene splint
- Where
- 3 sites in Canada
- Volunteers
- 56 people
- Sponsor
- University of British Columbia
Carpometacarpal Osteoarthritis
Effect of Perioperative Acetaminophen Dosing on Patients Undergoing Surgical Treatment of Basilar Thumb Arthritis
Basilar thumb arthritis is a common problem that affects 7% of men and 15% of women. It is regarded as one of the more painful procedures commonly performed by hand surgeons.
- Trial name
- NCT05556356
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Indiana Hand to Shoulder Center
Carpometacarpal (CMC) Osteoarthritis
Randomized Placebo Controlled Study of Triamcinolone Acetonide Extended Release Injection for Thumb (CMC) Osteoarthritis
The goal of this study is to investigate if a timed release steroid injection may be beneficial in treating carpometacarpal (CMC) joint (thumb) osteoarthritis. The main questions to be answered are: 1.
- Trial name
- NCT06237153
- Testing
- Triamcinolone Acetonide extended release suspension
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Marie Badalamente
Thumb Osteoarthritis
Distraction vs Interposition Arthroplasty for Basilar Thumb Osteoarthritis
Surgical management for osteoarthritis of the thumb is indicated when conservative measures have failed, and numerous techniques have been proposed.
- Trial name
- NCT04155853
- Testing
- Interposition Arthroplasty, Hematoma and Distraction Arthroplasty
- Where
- Greece
- Volunteers
- 22 people
- Sponsor
- Aristotle University Of Thessaloniki
Thumb Osteoarthritis, Proprioceptive Disorders
Position Sense, Force Control and Pain Intensity in Basal Thumb Osteoarthritis
In practice, a single test is used to quantify thumb proprioception. Previous studies have found a decrease in joint position sense (JPS) and force sense (FS) in patients diagnosis of thumb carpometacarpal osteoarthritis, but no…
- Conditions
- Thumb Osteoarthritis, Proprioceptive Disorders, Pain, Chronic
- Trial name
- NCT04819139
- Testing
- Active Excersises, Reeducation ADL, Joint protection
- Where
- Spain
- Volunteers
- 62 people
- Sponsor
- University of Malaga
Osteoarthritis Thumb
Arthroscopic Debridement vs Arthroscopic Hemi-Trapeziectomy on Patients With Thumb Carpometacarpal Joint Osteoarthritis
Patients with thumb carpometacarpal joint osteoarthritis usually suffer from pain, joint enlargement, inflammation, deformity and loss of function.
- Trial name
- NCT04217928
- Testing
- Arthroscopic Debridement, Arthroscopic Hemi-Trapeziectomy with Mini TightRope
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- Chinese University of Hong Kong
Osteoarthritis in the Carpometacarpal (CMC) Joint
CMC-1 Replacement Arthroplasty Versus Trapeziectomy
Thumb carpometacarpal (CMC-1) osteoarthritis is a common condition causing pain and disability, particularly among middle-aged and older women. When non-operative treatment fails, surgery is indicated.
- Trial name
- NCT07583628
- Volunteers
- 1,000 people
- Sponsor
- Karolinska Institutet
Soft Tissue Injuries, Distal Radius Fracture
Effectiveness of a Tele-Rehabilitation Evidence-based Tablet App for Rehabilitation in Traumatic Bone and Soft Injuries of the Hand, Wrist and Fingers.
Trauma and soft injuries of the wrist, hand and fingers have a high incidence, and large social and healthcare costs are generated, mainly due to productivity loss.
- Conditions
- Soft Tissue Injuries, Distal Radius Fracture, Metacarpal Fracture, Carpal Fracture
- Trial name
- NCT04669704
- Testing
- Experimental: Tablet application, Comparator: Conventional treatment
- Where
- 2 sites in Spain
- Volunteers
- 663 people
- Sponsor
- University of Seville
Osteoarthritis
Function Following Thumb MP Fusion and IP Fusion
This study is to determine function following simulated thumb metacarpophalangeal (MP) and thumb interphalangeal (IP) joint fusion. The investigators want to determine the functional limitation created by MP and IP joint fusion.
- Trial name
- NCT03661281
- Testing
- Jebsen Taylor Hand function test, Pinch strength, Grooved pegboard test
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health