Clinical trials: Thyroid
Recurrent Thyroid Cancer, Stage IV Follicular Thyroid Cancer
Tanespimycin in Treating Patients With Inoperable Locoregionally Advanced or Metastatic Thyroid Cancer
This phase II trial is studying how well tanespimycin works in treating patients with inoperable locoregionally advanced or metastatic thyroid cancer.
- Conditions
- Recurrent Thyroid Cancer, Stage IV Follicular Thyroid Cancer, Stage IV Papillary Thyroid Cancer, Thyroid Gland Medullary Carcinoma
- Trial name
- NCT00118248
- Testing
- tanespimycin
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- National Cancer Institute (NCI)
Congenital Hypothyroidism
Infants With Primary Congenital Hypothyroidism and Development
A review of the literature has focused primarily on the cognitive and motor development of children with congenital hypothyroidism, but no studies on sensory processing skills have been found.
- Trial name
- NCT07280104
- Testing
- neurological status, sensory processing functions, Motor development
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
Graves' Disease
Radioactive Iodide Therapy for Pediatric Graves' Disease
The investigators hypothesize that 131I is an effective therapy for children with Graves' Disease (GD) and will not be associated with long-term cancer risks when used in older children, but may be associated with excessive…
- Trial name
- NCT01269749
- Testing
- RAI treatment, ATD Group
- Where
- 2 sites in United States
- Volunteers
- 19 people
- Sponsor
- University of Florida
Medullary Thyroid Carcinoma
ImmunoTEP for Patients With Medullary Thyroid Carcinoma.
The aim of this study is to optimize pretargeting parameters using pharmacokinetic and imaging data for immuno-PET using anti-CEA x anti-HSG TF2 BsMAb and 150 MBq of 68Ga-IMP-288 peptide in MTC patients with abnormal Ct serum…
- Trial name
- iTEP-CMT (NCT01730638)
- Testing
- • TF2 and 68 Ga-IMP-288
- Where
- 3 sites in France
- Volunteers
- 25 people
- Sponsor
- Nantes University Hospital
Thyroid Cancer
Multiple Target Kinase Inhibitor and Anti-Programmed Death-1 Antibody in Patients With Advanced Thyroid Cancer
The study is being conducted to evaluate the safety and efficacy of Multiple Target Kinase Inhibitor(mTKI) Combined with Anti-Programmed Death-1(PD-1) Antibody in subjects with advanced thyroid cancer.
- Trial name
- NCT04521348
- Testing
- multiple tyrosine kinase inhibitor(mTKI) Combined with anti-PD-1 antibody
- Where
- China
- Volunteers
- 103 people
- Sponsor
- Fudan University
Thyroid Cancer
BRAF V600E and Redifferentiation Therapy in Radioiodine-refractory Papillary Thyroid Cancer
Papillary thyroid cancer (PTC) is the most common neoplasia in the thyroid gland. The combination of surgery, followed by radioiodine therapy (RIT) and thyroid-stimulating hormone (TSH) suppressive therapy is usually a curative…
- Trial name
- NCT03363347
- Testing
- Redifferentiation with retinoid acid
- Volunteers
- 25 people
- Sponsor
- Heidelberg University
Graves Disease, Graves Ophthalmopathy
Impact of Intravenous Methylprednisolone Treatment on Blood Pressure
Hypertension is common side effect of Cushing Syndrome (CS): in patients with endogenous CS and those treated with glucocorticosteroids (GCs). The impact of the intravenous GCs therapy on blood pressure (BP) remains unclear.
- Conditions
- Graves Disease, Graves Ophthalmopathy, Hypertension, Blood Pressure
- Trial name
- NCT03590080
- Testing
- Methylprednisolone
- Volunteers
- 32 people
- Sponsor
- Medical University of Warsaw
Objective Vocal Cord Movement Assessment by C-Mac Videolaryngoscope Vs Airway Ultrasound in Ca Thyroid
Comparison of Two Technique for Assessment of Vocal Cord Movement by C-Mac Videolaryngoscope vs Airway Ultrasound.
This study is planned to compare C-Mac video-laryngoscope and airway ultrasound as two novel techniques (causing least discomfort to the patients) for the detection of impaired vocal-cord movement after thyroid surgery.
- Trial name
- NCT02847780
- Testing
- Active Comparator :C-Mac Videolaryngoscope, Experimental: Airway ultrasound,
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Rajiv Gandhi Cancer Institute & Research Center, India
Subclinical Hypothyroidism, Sarcopenia
The Effect of Thyroid Hormone Therapy on Muscle Mass and Function in Older Adults With Subclinical Hypothyroidism
Subclinical hypothyroidism (SCH) is common among the elderly population and has been associated with neuromuscular impairment. Muscular symptoms such as weakness, myalgia and cramps are more often reported by SCH patients…
- Trial name
- NCT04354896
- Testing
- Levothyroxin
- Where
- 5 sites in Netherlands, Switzerland
- Volunteers
- 322 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Endocrine Disease
Comprehensive Data Collection and Follow-Up for Patients With Thyroid, Parathyroid and Adrenal Disease
The goal of this data review study is to collect data to learn more about thyroid, parathyroid, and adrenal disease.
- Trial name
- NCT03050762
- Testing
- Data Collection, Follow Up
- Where
- United States
- Volunteers
- 15,000 people
- Sponsor
- M.D. Anderson Cancer Center
Differentiated Thyroid Gland Carcinoma, Malignant Testicular Neoplasm
Personalized Cancer Support (Thrive Track) to Manage the Emotional Needs of Young Adults With Thyroid, Melanoma and Testicular Cancer, PerCS-YA Trial
This pilot clinical trial is intended to compare the effect of a psychosocial support tool for young adult (YA)cancer survivors - including high-quality information about their cancer combined with evidence-based psychosocial…
- Conditions
- Differentiated Thyroid Gland Carcinoma, Malignant Testicular Neoplasm, Melanoma, Thyroid Gland Follicular Carcinoma
- Trial name
- NCT07529080
- Testing
- Internet-Based Intervention, Interview, Questionnaire Administration
- Where
- United States
- Volunteers
- 142 people
- Sponsor
- University of Michigan Rogel Cancer Center
Huerthle Cell Carcinoma
Hürthle Cell Carcinoma and Follicular Thyroid Carcinoma
The goal of this retrospective study is to evaluate in patients with HCC and FTC who underwent lobectomy. The main questions it aims to answer are: The necessity of completion thyroidectomy based on the clinicopathological…
- Trial name
- HCC and FTC (NCT05968196)
- Volunteers
- 221 people
- Sponsor
- The Catholic University of Korea
Thyroid Cancer
Determination of Pronostics Factors for Advanced Thyroid Carcinoma (pT3 pT4 or M1 at Diagnosis)
It is generally estimated that 5 % of patients with thyroid cancer will develop distant metastases, and most of them had an advanced stage of the disease at presentation.
- Trial name
- NCT02156362
- Testing
- follow up visit
- Where
- France
- Volunteers
- 643 people
- Sponsor
- Hospices Civils de Lyon
Hypothyroidism Primary
Physical Activity, Fatigue, Social Support, and Psychological Well-Being in Women With Primary Hypothyroidism
Background. Primary hypothyroidism, both clinical and subclinical, is frequently associated with persistent fatigue, reduced psychological well-being, and lower levels of physical activity in adult women.
- Trial name
- NCT07408765
- Testing
- Women with primary hypothyroidism sample
- Where
- Spain
- Volunteers
- 96 people
- Sponsor
- University of Oviedo
Thyroid Cancer, Papillary Thyroid Carcinoma
Shared Decision-Making for Determining Treatment Strategies in Low-Risk Thyroid Cancer
This study is a multicenter cluster-randomized controlled trial conducted in Korea. A parallel, two-group cluster-randomized design will be used to test whether the Shared decision-making Group (SDM; intervention) is different…
- Trial name
- MAeSTro-SDM (NCT06730893)
- Testing
- SDM protocol
- Volunteers
- 310 people
- Sponsor
- National Cancer Center, Korea
Hypothyroidism
Neurocognitive and Metabolic Effects of Mild Hypothyroidism
Patients with hypothyroidism are routinely treated with thyroid hormone (l-thyroxine) for replacement therapy. Physicians monitor the thyroid hormone dose by measuring a thyroid stimulating hormone (TSH) level in the blood, with…
- Trial name
- NCT00565864
- Testing
- L-thyroxine (L-T4)
- Where
- United States
- Volunteers
- 173 people
- Sponsor
- Oregon Health and Science University
Anaplastic Thyroid Cancer
Evaluating Trends in Anaplastic Thyroid Cancer Patients' Clinical Study Experiences
Clinical trials can sometimes favor certain demographic groups. Additionally, there is limited research that delves into the factors that influence participation in clinical study, both positive and negative.
- Trial name
- NCT05819593
- Volunteers
- 500 people
- Sponsor
- Power Life Sciences Inc.
Hashimoto Thyroiditis, Graves Disease
DNA Methylation and Autoimmune Thyroid Diseases
Hashimoto Thyroiditis (HT) and Graves Disease (GD) are known to be caused by abnormal immune response against self cells and tissues.
- Trial name
- THYRODNA (NCT02491567)
- Where
- Greece
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Thyroid Nodular Disease
Microvascular Profiling of Nodules in the Thyroid Gland
The purpose of this study is to examine tiny blood vessels in different thyroid nodules using advanced ultrasound. In the long term, we hope this can help doctors better tell the difference between types of nodules and more…
- Trial name
- NCT07041307
- Where
- 2 sites in Denmark
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Hashimoto Thyroiditis
Comparison of the Effect of Gluten-Free-Lactose-Free / Aronia Melanocarpa Supplemented Diet in Patients With Hashimoto's Thyroiditis
Hashimoto's thyroiditis (HT) is the most common cause of chronic hypothyroidism in areas with sufficient iodine, stemming from an autoimmune response against thyroid peroxidase and/or thyroglobulin.
- Trial name
- NCT06419309
- Testing
- Dietary intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Halic University