Clinical trials: Thyroid Disorders
Thyroid Nodules
Elastography Interest in the Management of Thyroid Nodules
Define an ultrasound/elastography benignity criteria in strategy management of a patient population carries one or more thyroid nodules.
- Trial name
- SWETHY (NCT01335828)
- Testing
- Medical ultrasound device (ShearWave system)
- Where
- France
- Volunteers
- 125 people
- Sponsor
- AdministrateurCIC
Advanced Nonhaematologic Malignancies
Safety, Efficacy, and Tolerability of BOS172738 in Patients With Advanced Rearranged During Transfection (RET) Gene-Altered Tumors
This study will be conducted to assess the safety and tolerability of BOS172738 when administered to patients with advanced solid tumors with rearranged during transfection (RET) gene alterations and also to establish the maximum…
- Trial name
- NCT03780517
- Testing
- BOS172738
- Where
- 21 sites in United States, Belgium and 5 more
- Volunteers
- 117 people
- Sponsor
- Boston Pharmaceuticals
Thyroid Nodule
Compliance of Thyroid Fine Needle Aspiration Biopsy and Trucut Biopsy Results With TIRADS Score and Surgical Pathology
The investigators retrospectively reviewed the medical records of 760 patients with thyroid nodule biopsy and 88 patients who had thyroid surgery.
- Trial name
- TIRADS (NCT04488640)
- Testing
- Thyroid biopsy with ultrasound
- Volunteers
- 4 people
- Sponsor
- Bezmialem Vakif University
Non-Medullary Thyroid Cancer
Clinical and Genetic Studies in Familial Non-medullary Thyroid Cancer
Background: Researchers are studying types of thyroid cancer that seem to cluster in families. Non-medullary thyroid cancer accounts for the vast majority of all types of thyroid cancer, but little is known about possible genes…
- Trial name
- NCT01109420
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Parathyroid Function Low Adverse Event
Assessing Parathyroid Glands Vascularisation by ICG Fluoroscopy
Evaluate parathyroid gland perfusion during total thyroidectomy or thyroid totalisation surgery. Create an objective basis for the decision whether or not to transplant the parathyroid glands.
- Trial name
- NCT02249780
- Testing
- Postoperative parathyroid function test, No postoperative parathyroid dosage and supplementation, ICG parathyroid angiography
- Where
- Switzerland
- Volunteers
- 146 people
- Sponsor
- University Hospital, Geneva
Thyroid Surgery, Recurrent Laryngeal Nerve
Intraoperative Electromyographic Monitoring of the Recurrent Laryngeal Nerve in Thyroid Surgery
The purpose of this study will explore the advantages of electrodes used for monitoring of the recurrent laryngeal nerve (RLN) in thyroid surgery
- Conditions
- Thyroid Surgery, Recurrent Laryngeal Nerve, Electromyographic Monitoring
- Trial name
- NCT00629746
- Testing
- Medtronic Xomed Nerve Integrity Monitor (NIM)
- Where
- Taiwan
- Volunteers
- 1,000 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Evidence of Liver Transplantation
Changes of Macrophage Migration Inhibitory Factor During Orthotopic Liver Transplantation
Collecting blood, graft liver effluent and urine samples from patients undergoing orthotopic liver transplantation.
- Trial name
- NCT02695979
- Where
- Austria
- Volunteers
- 100 people
- Sponsor
- Medical University of Vienna
Graves' Disease
TSH Receptor Antibody Heterogeneity in Children and Adolescents With Graves' Disease
Graves' disease, the most common form of hyperthyroidism in children, is caused by Thyrotropin (TSH) Receptor Antibodies (TRAbs) that mimic the action of TSH.
- Trial name
- NCT00335062
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Boston Children's Hospital
Medullary Thyroid Cancer, Prositron Emission Tomography
68Ga-TCR-FAPI PET/CT Guided Precision Surgery for MTC
This is a phase II clinical trial to evaluate the capability of 68Ga-labeled targeted covalent radiopharmaceutical (TCR) fibroblast activation protein inhibitor (FAPI) PET/CT to guide the surgical treatment of medullary thyroid…
- Conditions
- Medullary Thyroid Cancer, Prositron Emission Tomography, Fibroblast Activation Protein Inhibitor, Surgery
- Trial name
- NCT06277180
- Testing
- Surgery
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Graves Orbitopathy, Hyperthyroidism
Development of a Non-Invasive Prognostic Test for Graves Orbitopathy
The aim of this research project is to develop a non-invasive, simple, robust, and sensitive prognostic test that can identify hyperthyroidism patients who are at risk of developing Graves' Orbitopathy.
- Trial name
- GoPro (NCT07472062)
- Testing
- Schirmer's test
- Where
- Belgium
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Thyroidectomy, Postoperative Neck Pain
Neck Exercises After Thyroid Surgery
Postoperative neck pain is common after thyroidectomy and may impair early recovery. This prospective randomized controlled study aimed to evaluate the effects of postoperative neck range-of-motion (ROM) and isometric…
- Conditions
- Thyroidectomy, Postoperative Neck Pain, Quality of Life (QOL), Cervical Range of Motion
- Trial name
- NCT07415174
- Testing
- Postoperative Neck Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Istanbul University - Cerrahpasa
Differentiated Thyroid Carcinoma, TCM Syndrome Type
Correlation Between TCM Syndrome Factors and TSH Changes of Thyroid Hormone Withdrawal Before Iodine Therapy in Postoperative Patients With Thyroid Cancer
The purpose of this study is to make a dialectical classification of patients who will receive 131I treatment after operation of thyroid cancer from the point of view of dialectics of syndrome elements of traditional Chinese…
- Trial name
- NCT04916262
- Volunteers
- 160 people
- Sponsor
- Qianfoshan Hospital
Differentiated Thyroid Cancer, Pediatric Cancer
Larotrectinib to Enhance RAI Avidity in Differentiated Thyroid Cancer
Papillary thyroid cancer (PTC) is the most common form of differentiated thyroid cancer (DTC). The traditional first line treatment for patients with advanced DTC after surgical resection is radioactive iodine (RAI) therapy.
- Conditions
- Differentiated Thyroid Cancer, Pediatric Cancer, Cancer, Cancer, Thyroid
- Trial name
- NCT05783323
- Testing
- Larotrectinib monotherapy, 131I therapy
- Where
- 6 sites in United States
- Volunteers
- 13 people
- Sponsor
- Children's Hospital of Philadelphia
Papillary Thyroid Microcarcinoma, Radiofrequency Ablation
10 Years' Follow-up Results of Ultrasound-guided Radiofrequency Ablation Versus Surgery for Low-risk Papillary Thyroid Micro-carcinoma
Papillary thyroid micro-carcinoma (PTMC) generally demonstrates favorable prognosis. However, the potential risk of disease progression requires careful therapeutic consideration.
- Conditions
- Papillary Thyroid Microcarcinoma, Radiofrequency Ablation, Surgical Resection, Long-term Outcomes
- Trial name
- NCT07107503
- Testing
- Radiofrequency ablation alone, surgical resection
- Volunteers
- 757 people
- Sponsor
- Yi Mao
Vitiligo Vulgaris
Online Health Survey of Patients With Vitiligo Vulgaris/ Online Survey of Pediatric Patients With Vitiligo
The study is an on-line survey posted on survey monkey that addresses some demographic and environmental issues that could potentially relate to vitiligo vulgaris onset or disease exacerbation.
- Trial name
- NCT01401374
- Where
- United States
- Volunteers
- 3,258 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Thyroid Volume, Thyroid Ultrasound
Ultrasound Measurement of Thyroid Volume in Term Newborns
First, to date, no data are available on the thyroid volume of full-term newborns in Italy, making it essential to conduct studies to establish reference values for normality.
- Conditions
- Thyroid Volume, Thyroid Ultrasound, Congenital Hypothyroidism, Healthy Newborns
- Trial name
- NEOTIR (NCT07579988)
- Testing
- Thyroid ultrasound
- Where
- Italy
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- IRCCS Ospedale San Raffaele
Amiodarone-Induced Thyrotoxicosis
Radiofrequency Ablation for Amiodarone-induced Thyrotoxicosis
Investigators intend to study the changes in thyroid hormone storage and production in amiodarone-induced thyrotoxicosis patients after RFA therapy.
- Trial name
- NCT03720210
- Testing
- RFA
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Mayo Clinic
Leukaemia (Chronic)
What is the Impact of TKI on Thyroid Function in CML Patients?
Evaluation of the impact of various TKI on thyroid function in patients diagnosed with cml
- Trial name
- NCT07200882
- Volunteers
- 76 people
- Sponsor
- Assiut University
Hyperthyroidism; Goiter, Multinodular Goiter
Pressure-enabled Retrograde Occlusive Therapy With Embolization for Control of Thyroid Disease (PROTECT Registry): A Multicenter Registry
Multi-center registry study to evaluate disease-related quality of life outcomes of thyroid embolization via pressure-enabled delivery (PED-TAE).
- Conditions
- Hyperthyroidism; Goiter, Multinodular Goiter, Thyroid Nodules, Thyroid Disease
- Trial name
- NCT06868459
- Testing
- Data Collection
- Where
- 4 sites in United States
- Volunteers
- 100 people
- Sponsor
- Sarasota Memorial Health Care System
Thyroid Cancer, Thyroid Cancer, Papillary
Intraoperative Neuromuscular Monitoring and Its Impact on Pre- and Postoperative Acoustic Outcomes in Thyroid Surgery
This study examines the impact of intraoperative recurrent laryngeal nerve monitoring signal changes on the postoperative voice quality of thyroid surgery patients.
- Trial name
- NCT06254859
- Testing
- Traditional thyroid surgery.
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Fujian Medical University
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