Clinical trials: Thyroid Dysfunction, open to volunteers
Thyroid Dysfunction, Hemodialysis
Evaluation of Thyroid Function, Lipid Profile, and Uric Acid Levels in Hemodialysis Patients
This observational study evaluates the prevalence and relationships of thyroid dysfunction, lipid abnormalities, and elevated uric acid levels in adult patients undergoing maintenance hemodialysis at Assiut University Hospital.
- Conditions
- Thyroid Dysfunction, Hemodialysis, Elevated Uric Acid
- Trial name
- NCT07157267
- Volunteers
- 100 people
- Sponsor
- Assiut University
Thyroid Eye Disease, Graves Ophthalmopathy
The Effect of Teprotumumab on Thyroid Eye Disease and Thyroid Dysfunction
This protocol studies the clinical outcome of patients with active thyroid disease with visually significant signs and symptoms of proptosis, pain, diplopiam lid/orbital edema, or lid/orbital erythema recommended for treatment…
- Conditions
- Thyroid Eye Disease, Graves Ophthalmopathy, Graves Disease
- Trial name
- Teprotumumab (NCT06275373)
- Testing
- Teprotumumab Injection [Tepezza]
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Walter Reed National Military Medical Center
GI Disorders
Esophageal Motility and Gastric Emptying Disorders Among Different Thyroid Dysfunction
Detect prevalence of different gastroparesis symptoms among different thyroid disorders Effect of thyroid disorders either hypothyroidism, hyperthyroidism and subclinical disorders in upper gastro motility
- Trial name
- NCT07069816
- Testing
- Scintigraphy
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Dialysis; Complications
Assessment of Thyroid Dysfunction in Patients Undergoing Haemodialysis at Sohag University Hospital
Thyroid dysfunction is a prevalent endocrine disorder that significantly impacts the health of patients with chronic kidney disease (CKD), particularly those undergoing dialysis.
- Trial name
- NCT07022236
- Testing
- Thyroid profile
- Where
- Egypt
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Sohag University
High-risk Pregnancy
Association of Maternal Thyroid Function and Anxiety With Fetal Cardiotocography Parameters in High-Risk Pregnancies
This prospective observational study aims to investigate the association between maternal thyroid function, maternal anxiety levels, and fetal cardiotocography parameters in high-risk pregnancies.
- Trial name
- NCT07774949
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Istanbul Training and Research Hospital
Ocular Motility Disorders, Strabismus
Clinical Validation of AI-Based Quantitative Eye Movement Analysis From Smartphone 9-Gaze Videos (Glandy EOM)
This prospective, multicenter, multinational observational study evaluates the clinical validity of an AI-based quantitative eye movement analysis system (Glandy EOM) that analyzes smartphone-recorded 9-gaze videos.
- Conditions
- Ocular Motility Disorders, Strabismus, Extraocular Muscle Dysfunction, Thyroid Eye Disease
- Trial name
- GLANDY-EOM-VAL (NCT07623837)
- Testing
- Glandy EOM (AI-based quantitative eye movement analysis software)
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- THYROSCOPE INC.
Thyroid Nodule, Thyroid Dysfunction
Postoperative Hypocalcemia After Thyroidectomy
This retrospective cohort study investigates predictors of postoperative hypocalcemia following thyroidectomy procedures at Minia University Hospital over a 10-year period (2014-2024).
- Conditions
- Thyroid Nodule, Thyroid Dysfunction, Hypocalcemia, Thyroid Cancer
- Trial name
- NCT07428057
- Where
- Egypt
- Volunteers
- 600 people
- Sponsor
- Minia University
Geriatric Diseases
Thyroid Dysfunction in Elderly
Thyroid dysfunction in elderly
- Trial name
- Thyroid dysfun (NCT07606560)
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- Assiut University
Thyroid; Functional Disturbance, Hypothyroidism
A Randomized Controlled Trial of Thyroid Hormone Supplementation in Hemodialysis Patients
Hypothyroidism, defined by elevated thyrotropin (TSH) levels, is a common endocrine complication in chronic kidney disease patients, and prior evidence shows that higher TSH levels, even within the normal laboratory range, are…
- Conditions
- Thyroid; Functional Disturbance, Hypothyroidism, Hemodialysis
- Trial name
- THYROID-HD (NCT03977207)
- Testing
- Levothyroxine Sodium
- Where
- United States
- Volunteers
- 336 people
- Sponsor
- University of California, Irvine
Thyroid Surgery, Parathyroid Dysfunction
PTeye vs Surgeons Eyes in Intraoperative Identification and Functional Preservation of Parathyroid Glands During Thyroid Surgery: A Parallel Randomized Controlled Clinical Trial.
The goal of this randomized clinical trial is to learn if there are any added benefits of using near-infrared autofluorescence (NIRAF) probe-based imaging system (the PTeye) for intraoperative identification of parathyroid glands…
- Conditions
- Thyroid Surgery, Parathyroid Dysfunction, Hypoparathyroidism Post-surgical
- Trial name
- PTSURGEYE (NCT06765941)
- Testing
- Probe-based near-infrared parathyroid autofluorescence detection system, Surgeons naked eyes for parathyroid glands identification
- Where
- Poland
- Volunteers
- 154 people
- Sponsor
- Marcin Barczynski
Metabolic Dysfunction-Associated Steatotic Liver Disease, Hypothyroidism
Hypothyroidism and Liver Fibrosis Severity in MASLD
Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most common chronic liver disease worldwide, characterized by excess fat accumulation in the liver associated with metabolic risk factors such as obesity and…
- Conditions
- Metabolic Dysfunction-Associated Steatotic Liver Disease, Hypothyroidism, Liver Cirrhosis, Non-Alcoholic Fatty Liver Disease
- Trial name
- NCT07793279
- Volunteers
- 85 people
- Sponsor
- Assiut University
Thyroid Nodule, Thyroid Cancer
Cognition and QoL After Thyroid Surgery
The development of cognitive dysfunction can profoundly affect HR-QoL as well as the possibility of societal participation and ability to work, and thereby relevantly impacts prospects for cancer survivorship.
- Conditions
- Thyroid Nodule, Thyroid Cancer, Cognitive Decline, Survivorship
- Trial name
- NCT05088187
- Where
- Sweden
- Volunteers
- 320 people
- Sponsor
- Karolinska University Hospital
Brest Cancer
Thyroid Dysfunction Induced by Radiotherapy Treatment in Patients with Breast Cancer
Breast cancer is the most common cancer and second most common cause of cancer death among US women,. External beam radiation therapy (RT) that involves the breast and regional lymph nodes, including axillary and supraclavicular…
- Trial name
- NCT06820554
- Volunteers
- 97 people
- Sponsor
- Assiut University
Thyroid Dysfunction, Immune Thrombocytopenic Purpura
Study of Thyroid Dysfunction in Immune Thrombocytopenic Purpura Patients
Study of relation between thyroid dysfunction and immune thrombocytopenic purpura patients and if there is relation between them
- Trial name
- NCT07900334
- Testing
- Laboratory tests TSH, FT3, FT4 ,anti thyroglobulin antibodies, Anti -TPO antibodies
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sohag University
Metabolic Dysfunction-associated Steatohepatitis
A Study of a Thyroid Hormone Receptor Beta Isoform (THRβ) Agonist and an Semicarbazide Sensitive Amine Oxidase (SSAO) Inhibitor, Alone and in Combination, in Adults With Presumed Metabolic Dysfunction-associated Steatohepatitis (MASH)
The primary objective of this trial is to evaluate the dose-dependent and comparative effects of ECC4703 (low and high dose), ECC0509 (low and high dose), and their combination on hepatic fat reduction as assessed by change in…
- Trial name
- NCT07288138
- Testing
- ECC4703, ECC0509
- Where
- 68 sites in United States
- Volunteers
- 160 people
- Sponsor
- Eccogene
Coronary Stenosis, Cerebral Arterial Diseases
Wearable Devices Assist in the Detection, Screening, and Management of Major Diseases in Middle-aged and Elderly Populations
The goal of this randomized controlled trial is to evaluate the effectiveness of wearable devices (Huawei smartwatches) in aiding the detection, and screening of major diseases (e.g., coronary artery disease, hypertension) in…
- Conditions
- Coronary Stenosis, Cerebral Arterial Diseases, Hypertension, Parkinson Disease
- Trial name
- NCT06980064
- Testing
- Smartwatch + GP, GP only
- Volunteers
- 800 people
- Sponsor
- Tongji Hospital
Thyroid Dysfunction, Metabolic Dysfunction-Associated Fatty Liver Disease
Thyroid Dysfunction and Its Association With Metabolic Dysfunction-Associated Fatty Liver Disease
This study aims to evaluate the prevalence of thyroid dysfunction and its association with metabolic dysfunction-associated fatty liver disease.
- Trial name
- NCT06739330
- Testing
- Fibroscan
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Tanta University
Metabolic Dysfunction-Associated Steatotic Liver Disease, Non-Alcoholic Fatty Liver Disease
Impact of Overt and Subclinical Hypothyroidism on Liver Fibrosis in Patients With MASLD
Metabolic dysfunction-associated steatotic liver disease (MASLD), previously known as non-alcoholic fatty liver disease (NAFLD), is one of the most common chronic liver conditions globally.
- Conditions
- Metabolic Dysfunction-Associated Steatotic Liver Disease, Non-Alcoholic Fatty Liver Disease, Hypothyroidism, Liver Fibrosis
- Trial name
- NCT07827430
- Volunteers
- 120 people
- Sponsor
- Assiut University
Thyroid Dysfunction
Prevalence and Prognostic Effects of Thyroid Abnormalities in Patients With Acute Coronary Syndrome.
The goal of this observational study is knowledge of Prevalence of throid abnormalities in patients with acute coronary syndrome And prognostic effects of thyroid abnormalities in patients with acute coronary syndrome as early…
- Trial name
- NCT06579014
- Volunteers
- 129 people
- Sponsor
- Assiut University
Sleep Bruxism, Hypertension
Selected Disorders and Sleep Bruxism
Sleep apnea is a common and serious health problem in the Polish population. According to epidemiological data problem concerns about 7% of the adult population. The most common sleep disorder is obstructive sleep apnea (OSA).
- Conditions
- Sleep Bruxism, Hypertension, Thyroid Dysfunction, Mental Status Change
- Trial name
- NCT03083405
- Testing
- Opipramol
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University