Clinical trials: Thyroid Gland Nodule
Hurthle Cell Thyroid Cancer, Tall Cell Variant Thyroid Cancer
Studies on Tumors of the Thyroid
Participants in this study will be patients diagnosed with or suspected to have a thyroid nodule or thyroid cancer. The main purpose of this study is to further understand the methods for the diagnosis and treatment of thyroid…
- Conditions
- Hurthle Cell Thyroid Cancer, Tall Cell Variant Thyroid Cancer, Follicular Thyroid Cancer, Thyroid Cancer
- Trial name
- NCT00001160
- Testing
- 68-Gallium Dotatate
- Where
- United States
- Volunteers
- 2,500 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Thyroid Nodule, Thyroid Cancer
Assessment the Cancer Risk of Indeterminate Thyroid Nodules Through Integration of Clinical, Ultrasonographic and Multiomic Features
Indeterminate thyroid nodules have a mild risk of malignancy (15-30%). The aim of our study is to individuate new biomarkers of thyroid carcinoma through multiomic analyses of blood samples and of specimen samples of patients…
- Trial name
- THYOMICS (NCT05428371)
- Testing
- Multiomic analyses of blood and surgical specimens
- Where
- Italy
- Volunteers
- 256 people
- Sponsor
- University of Cagliari
Multinodular Goitre, Grave's Disease
A Prospective Randomized Equivalence Trial to Evaluate the Safety of the Ligasure in Thyroid Surgery
This is a randomized, prospective equivalence trial on the safety of the Ligasure Vessel Sealing System as used in thyroid surgery.
- Conditions
- Multinodular Goitre, Grave's Disease, Thyroid Nodule
- Trial name
- NCT01163565
- Testing
- Ligasure Device
- Where
- Canada
- Volunteers
- 96 people
- Sponsor
- University of Alberta
Thyroid Nodule, Thyroid Neoplasms
Khon Kaen University's Thyroidectomy Registry
The endoscopic thyroidectomy approach is gaining popularity in the surgical field. This registry tries to collect the outcomes including quality of life and complication for both endoscopic and conventional thyroidectomy methods.
- Conditions
- Thyroid Nodule, Thyroid Neoplasms, Thyroid Cancer
- Trial name
- NCT03031639
- Testing
- Endoscopic approach thyroidectomy
- Where
- Thailand
- Volunteers
- 98 people
- Sponsor
- Khon Kaen University
Elastography, Thyroid Nodule
Diagnostic Performance of Ultrasound Elastography for Detection of Thyroid Cancer
For patients with thyroid gland nodule, fine-needle aspiration biopsy has been proved to be an efficient tool for thyroid cancer diagnosis.
- Trial name
- Elastography (NCT02462512)
- Where
- South Korea
- Volunteers
- 590 people
- Sponsor
- Dong Jun Lim
Thyroid Nodule (Diagnosis), Thyroid Cancer
Thyroid Nodule Gene Sequencing in a Danish Population
This pilot study aims at describing the prevalence and distribution of molecular alterations in thyroid nodules of benign and malignant origin at the level of DNA and RNA in a Danish population.
- Trial name
- NCT05377736
- Testing
- Molecular analyses
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Aarhus University Hospital
Hypocalcemia, Hypoparathyroidism
NIRAF-Guided Parathyroid Identification During Thyroidectomy
This is a single-site, two-component prospective study evaluating whether near-infrared autofluorescence (NIRAF) imaging can improve intraoperative identification of parathyroid glands during thyroidectomy and reduce…
- Conditions
- Hypocalcemia, Hypoparathyroidism, Thyroid Diseases, Goiter, Nodular
- Trial name
- NCT07617584
- Testing
- Wearable Near-Infrared Autofluorescence Imaging System
- Where
- North Macedonia
- Volunteers
- 280 people
- Sponsor
- Ss. Cyril and Methodius University of Skopje
Thyroid Nodule (Diagnosis)
Safety & Feasibility of Ultrasound-assisted Non-invasive Measurement of Compressibility of the Thyroid Gland in Patients Scheduled for Surgical Removal
The thyroid gland plays an important role in hormone regulation however, it is often prone to nodules. This is common with nodules being found in up to 68% of people in a neck ultrasound, with likelihood increasing with age.
- Trial name
- NCT07102264
- Testing
- CPMX1
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Thyroid Nodule, Thyroid Neoplasms
The Role of Elastography in the Diagnosis of Thyroid Nodules
The primary objective of this study is to evaluate the role of elastography (along with echographic and cytological data) as a diagnostic tool for thyroid cancer
- Trial name
- NCT01292044
- Testing
- Elastography
- Where
- France
- Volunteers
- 188 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Benign Thyroid Nodule
Cryoablation of Benign Thyroid Nodules: a Pilot Study
This study will evaluate the clinical response and safety of ultrasound guided percutaneous cryoablation in the treatment of benign thyroid nodules as an alternative to the surgery.
- Trial name
- NCT06014229
- Testing
- cryoablation
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- University of Sao Paulo General Hospital
Thyroid Nodule
B-mode Ultrasound, Sono-Elastography, and Diffusion-weighted Imaging MRI in Thyroid Nodules
To compare the accuracy of the conventional Ultrasound 'TI-RADS', US elastography, DWI MRI, and its ADC value in characterization and differentiation of thyroid nodules.
- Trial name
- NCT06029946
- Testing
- elastography, ultrasound
- Volunteers
- 50 people
- Sponsor
- Assiut University
Thyroid Nodule, Thyroid Cancer
NGS-based Thyroscan Genomic Classifier in the Diagnosis of Thyroid Nodules
The purpose of this study is to evaluate the accuracy of Thyroscan in the differential diagnosis of benign and malignant thyroid nodules with suspecious ultrasound features
- Trial name
- NCT05025046
- Testing
- Thyroscan
- Where
- 4 sites in China
- Volunteers
- 250 people
- Sponsor
- Rigen Biotech
Thyroid Nodule
Decision Aid and Thyroid Nodules Management
Patients with small favorable malignant or indeterminate thyroid nodules will receive information about management of thyroid nodules.
- Trial name
- NCT05264857
- Testing
- Thyroid Nodule Management Education
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- Stony Brook University
Thyroid Nodules
Contrast-enhanced Ultrasound-guided Fine-needle Aspiration Biopsy in the Evaluation of Thyroid Nodules
To evaluate the application value of contrast-enhanced ultrasound in the diagnosis of thyroid nodules using fine needle aspiration.
- Trial name
- NCT03102099
- Testing
- contrast-enhanced ultrasound group, conventional ultrasound group
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Peking University Third Hospital
Thyroid Nodule
The Application Value of Deep Learning-Based Nomograms in Benign-Malignant Discrimination of TI-RADS Category 4 Thyroid Nodules
This retrospective study focuses on benign and malignant classification of thyroid nodules using deep learning techniques and evaluates the value of deep learning based nomograms in the classification of TI-RADS category 4…
- Trial name
- NCT06258044
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Ma Zhe
Thyroid Cancer, Thyroid Nodule
Voice Outcomes Following Thyroidectomy
This is an observational study of voice outcomes in participants following thyroidectomy or another head and neck surgery that does not involve risk to the larynx other than risks incurred due to intubation alone.
- Trial name
- NCT03657654
- Testing
- No intervention: observational only
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Virginia
Thyroid Cancer
An Easy Sonographic Scoring System for Predicting Malignant Thyroid Nodules
The purpose of the investigators study is to retrospectively evaluate the predictors of malignant thyroid nodules and established an useful scoring system based on sonographic findings and demographic data.
- Trial name
- NCT01307761
- Where
- Taiwan
- Volunteers
- 500 people
- Sponsor
- Far Eastern Memorial Hospital
Thyroid Cancer
Differential Diagnosis and Clinical Treatment Strategies of Thyroid Nodules.
To investigate the genetic mutations of patients with thyroid carcinoma and find molecular targets for therapy.
- Trial name
- NCT02953288
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Shanghai 10th People's Hospital
Surgical Wound Infection, Thyroid Nodule
Comparing Efficacy of Postoperative Oral Antibiotic Use in Trans-Oral Thyroidectomy
Transoral endoscopic thyroid surgery is a emerging surgical technique for thyroid surgery. This study to investigate the need for postoperative antibiotics in transoral endoscopic thyroid surgery.
- Trial name
- POTO (NCT03295955)
- Testing
- Amoxicillin Clavulanate
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Seoul National University Hospital
Indeterminate Thyroid Cytology
Validation of a Multi-Genetic Test for the Diagnosis of Indeterminate Thyroid Nodules
A clinical trial is proposed, to clinically validate the diagnostic performance of a new genetic test developed in Chile. It will determine the nature of thyroid nodules that have been informed as indeterminate by cytology…
- Trial name
- CT-DS (NCT03061318)
- Where
- 9 sites in Chile
- Volunteers
- 3,100 people, healthy volunteers welcome
- Sponsor
- Hernán González