Clinical trials: Thyroid Gland Nodule
Thyroid Diseases, Thyroid Neoplasms
Thyroid Health Outcomes Registry for Surgery
THORS is a single-center ambidirectional observational cohort study conducted at Moscow Multidisciplinary Clinical Center "Kommunarka".
- Conditions
- Thyroid Diseases, Thyroid Neoplasms, Thyroid Cancer, Thyroid Nodules
- Trial name
- THORS (NCT07812779)
- Volunteers
- 3,000 people
- Sponsor
- Pirogov Russian National Research Medical University
Thyroid Nodules
Realtime-Elastography (RTE) and Thyroid Nodules
The study is an open, prospective multicenter study. According to the statistical sample size calculation 593 patients with thyroid nodules ≥ 5mm in size will be included in the study.
- Trial name
- NCT01609946
- Testing
- Realtime-Elastography, linear ultrasound probe, Hitachi EUB-900, Japan, Cytology (FNAB) or Surgery
- Where
- 10 sites in Germany
- Volunteers
- 602 people
- Sponsor
- Johannes Vermehren
Thyroid Nodule
B-mode Ultrasound, Sono-Elastography, and Diffusion-weighted Imaging MRI in Thyroid Nodules
To compare the accuracy of the conventional Ultrasound 'TI-RADS', US elastography, DWI MRI, and its ADC value in characterization and differentiation of thyroid nodules.
- Trial name
- NCT06029946
- Testing
- elastography, ultrasound
- Volunteers
- 50 people
- Sponsor
- Assiut University
Thyroid Nodules
Patients Who Underwent Thyroid Ultrasonography at Our Institution Were Selected for Shear Wave Elastography of Thyroid Nodules, and the Maximum and Mean Values of the Modulus of Elasticity of the Nodules in Transverse and Longitudinal Sections Were Analyzed.
The objective of this observational study was to evaluate the effect of transverse and longitudinal sections on the measurement of thyroid nodule stiffness by shear wave elastography.
- Trial name
- SWE (NCT06007859)
- Testing
- section orientation
- Where
- China
- Volunteers
- 67 people
- Sponsor
- Ma Zhe
Thyroid Neoplasm
Validation of the Diagnostic Accuracy of the Electronic Nose in the Detection of Thyroid Cancer
Patients with a suspected thyroid nodule face an invasive and patient unfriendly diagnostic work-up to determine the risk of malignancy.
- Trial name
- NCT04883294
- Testing
- Electronic Nose
- Volunteers
- 1,500 people
- Sponsor
- Maastricht University Medical Center
Thyroid Nodule, Thyroid Cancer
HRQOL in Thyroid Cancer and Thyroid Tumours
Background: Most patients with thyroid cancer have a long life expectancy, and it has been assumed among health professionals that therefore the quality of life (QOL) is good.
- Conditions
- Thyroid Nodule, Thyroid Cancer, Quality of Life
- Trial name
- NCT03676348
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- Oslo University Hospital
Thyroid Nodule
the Effect of Universal Salt Iodization on Thyroid Diseases
1. acquire the environmental iodine status of Hangzhou 2. acquire the iodine status of population in Hangzhou 3. acquire the prevalence of thyroid diseases in Hangzhou 4.
- Trial name
- NCT01838629
- Where
- China
- Volunteers
- 12,438 people, healthy volunteers welcome
- Sponsor
- Weimin Xu
Thyroid Nodules, Thyroid Cancer
AIM2: Adequate Selection of Patients for Thyroid Biopsy: Evaluation of a Shared Decision Making Conversation Aid
There is an epidemic of thyroid cancer that is harmful to patients and the medical system. The study hypothesizes that the use of an electronic conversation aid during clinical visits can help patients and clinicians collaborate.
- Trial name
- NCT04463719
- Testing
- Counseling using the electronic conversation aid, counseling by routine care
- Where
- 2 sites in United States
- Volunteers
- 107 people
- Sponsor
- University of Florida
Head and Neck Cancer
Genetic Analysis in Diagnosing Thyroid Cancer in Patients With Thyroid Nodules
RATIONALE: Finding genetic markers for thyroid cancer in a biopsy specimen may help doctors diagnose thyroid cancer. PURPOSE: This clinical trial is studying how well genetic analysis works in diagnosing thyroid cancer in…
- Trial name
- NCT00316823
- Testing
- gene expression analysis, polymerase chain reaction, reverse transcriptase-polymerase chain reaction
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- University of California, San Francisco
Thyroid Nodule
Skin-crease Thyroidectomy
We performed a retrospective observational-analytic study. Anatomical measurements were performed on 118 participants during an ultrasound exam, and demographic data was collected from their medical files.
- Trial name
- NCT04248114
- Testing
- Ultrasound of the Neck
- Volunteers
- 118 people
- Sponsor
- Western Galilee Hospital-Nahariya
Metabolic Syndrome, Thyroid Nodule
Relationship of Metabolic Syndrome and Its Components With Thyroid Nodule(s)
To investigate the association between metabolic syndrome (MS) and thyroid nodule(s).
- Trial name
- NCT03009279
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Lin Liao
Cancer, Thyroid
Thyroid Ultrasound Elasticity (TrUE) Imaging
In this study the researchers will scan the thyroid nodules of patients scheduled for surgical removal of these nodules. During their preadmission testing, but prior to their surgery, the researchers will perform standard…
- Trial name
- NCT03307694
- Testing
- Ultrasound, Shear wave elasticity imaging, Multi-angle compound shear wave elasticity imaging
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Emory University
Benign Thyroid Gland Neoplasm, Recurrent Thyroid Gland Carcinoma
Radiofrequency Ablation for the Treatment of Benign or Low Risk Thyroid Nodule
This phase IV trial studies the effect of radiofrequency ablation in treating patients with benign or low risk thyroid nodule. Radiofrequency ablation uses a needle to deliver a high-frequency electric current to kill tumor cells…
- Conditions
- Benign Thyroid Gland Neoplasm, Recurrent Thyroid Gland Carcinoma, Thyroid Gland Follicular Tumor of Uncertain Malignant Potential, Thyroid Gland Nodule
- Trial name
- NCT05003856
- Testing
- Quality-of-Life Assessment, Radiofrequency Ablation
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- M.D. Anderson Cancer Center
Low Risk, Papillary Thyroid Cancer
Radiofrequency Ablation for Management of Benign/Indeterminate Thyroid Nodules and Low Risk Papillary Thyroid Cancers
To track the outcomes of patients who have been treated with RFA and its long-term effectiveness, and to learn more about the quality of life of patients who have received RFA in this study.
- Conditions
- Low Risk, Papillary Thyroid Cancer, Radiofrequency Ablation
- Trial name
- NCT07140757
- Testing
- Questionnaire
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- M.D. Anderson Cancer Center
Malignancy of Thyroid Nodules
Value of the Combination Ultrasonography With Ti-RADS Score / Dual Tracer Scintigraphy MIBI-Tc99m/Iodine-123 in the Detection of Malignancy of Thyroid Nodules (≥15 mm) Classified Bethesda III or IV on Cytology
The main objective of the study is to show that the addition of ultrasonography to the dual tracer scintigraphy MIBI-Tc99m/Iodine-123 will increase (at least +5%) the negative predictive value compared to the dual tracer…
- Trial name
- MIBI-THYR (NCT03498183)
- Testing
- MIBI-Tc99m/Iodine-123
- Where
- 7 sites in France
- Volunteers
- 372 people
- Sponsor
- Nantes University Hospital
Differentiated Thyroid Cancer (DTC), Papillary Thyroid Carcinoma
Serum Treg/Th17-Related Cytokines and Systemic Inflammatory Indices in Differentiated Thyroid Cancer
This study measures circulating immune-signaling molecules before thyroid surgery to determine whether they differ between patients whose thyroid nodule proves to be a differentiated thyroid carcinoma and patients whose nodule…
- Conditions
- Differentiated Thyroid Cancer (DTC), Papillary Thyroid Carcinoma, Thyroid Cancer, Thyroid Nodule
- Trial name
- THINC (NCT07907432)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Marmara University
Thyroid Nodule, Thyroid Dysfunction
Postoperative Hypocalcemia After Thyroidectomy
This retrospective cohort study investigates predictors of postoperative hypocalcemia following thyroidectomy procedures at Minia University Hospital over a 10-year period (2014-2024).
- Conditions
- Thyroid Nodule, Thyroid Dysfunction, Hypocalcemia, Thyroid Cancer
- Trial name
- NCT07428057
- Where
- Egypt
- Volunteers
- 600 people
- Sponsor
- Minia University
Thyroid Gland Carcinoma
Evaluation of DNA Methylation Signatures for the Diagnosis and Management of Thyroid Nodules
This clinical trial evaluates deoxyribonucleic acid (DNA) methylation signatures in diagnosing and managing thyroid nodules. The purpose of this research is to develop a new test for thyroid cancer.
- Trial name
- NCT05229341
- Testing
- Diagnostic Procedure, Electronic Health Record Review, Needle Biopsy
- Where
- United States
- Volunteers
- 1,450 people
- Sponsor
- City of Hope Medical Center
Thyroid Nodules
Hemodynamic Parameters in Euthyroid Patients With Thyroid Nodules
The purpose of this study is to determine the relationship of hemodynamic parameters with the level of thyroid hormones and the histological structure of thyroid nodules in euthyroid patients.
- Trial name
- NCT00507897
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- Yaroslavl State Medical Academy
Thyroid Gland Carcinoma
Identification and Differentiation of Thyroid Nodules by Acoustic Imaging and Viscoelastic Parameters
This study is being done to identify and differentiate thyroid nodules by acoustic imaging and viscoelastic parameters.
- Trial name
- NCT06207188
- Testing
- Non-Interventional Study
- Where
- 3 sites in United States
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic