Clinical trials: Thyroid Lobectomy
Papillary Thyroid Carcinoma, Central Compartment Neck Dissction
The Role of Prophylactic Central Compartment Neck Dissection in the Management of 2 to 4 cm Papillary Thyroid Carcinoma
Papillary thyroid carcinoma (PTC) is the most common endocrine malignancy and is frequently associated with microscopic central neck lymph node metastases, even in the absence of preoperative clinical evidence of nodal…
- Conditions
- Papillary Thyroid Carcinoma, Central Compartment Neck Dissction, Thyroidectomy, Thyroid Lobectomy
- Trial name
- PRO-COMAND (NCT06899347)
- Testing
- Total Thyroidectomy + Central Compartment Neck Dissection, Thyroid Lobectomy + ipCCND
- Volunteers
- 392 people
- Sponsor
- Leonardo Rossi
Thyroid Nodule
Intervention in Single Thyroid Nodule.
Thyroid nodules are common clinical problem. The incidence is 2-4 per 100,000 people per year, being more common in women and the elderly.
- Trial name
- NCT05658809
- Testing
- thyroidectomy
- Volunteers
- 40 people
- Sponsor
- Assiut University
Papillary Thyroid Cancer, Papillary Carcinoma
More Than 50% of Unifocal cN0 T1b/Small T2 Papillary Thyroid Carcinoma May Require Completion Thyroidectomy if Nodal Status is Evaluated
In absence of nodal metastases or aggressive features, thyroid lobectomy (TL) should be preferred over total thyroidectomy (TT) for small unifocal papillary thyroid carcinoma (PTC).
- Conditions
- Papillary Thyroid Cancer, Papillary Carcinoma, Thyroid Cancer, Thyroid Carcinoma
- Trial name
- cN0PTC (NCT06439745)
- Volunteers
- 314 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Thyroid Diseases, Thyroid Neoplasms
Thyroid Health Outcomes Registry for Surgery
THORS is a single-center ambidirectional observational cohort study conducted at Moscow Multidisciplinary Clinical Center "Kommunarka".
- Conditions
- Thyroid Diseases, Thyroid Neoplasms, Thyroid Cancer, Thyroid Nodules
- Trial name
- THORS (NCT07812779)
- Volunteers
- 3,000 people
- Sponsor
- Pirogov Russian National Research Medical University
Differentiated Thyroid Cancer
Hemithyroidectomy or Total-Thyroidectomy in 'Low-risk' Thyroid Cancers
This is a multi-centre, randomised, non-inferiority, phase III study in patients with low risk differentiated thyroid cancer. Patients will be identified via oncology multidisciplinary team meetings.
- Trial name
- HoT (NCT05604963)
- Testing
- Total Thyroidectomy, Hemithyroidectomy
- Where
- 33 sites in United Kingdom
- Volunteers
- 456 people
- Sponsor
- University College, London
Thyroid Nodule
Surgical Versus Non Surgical Management of Thyroid Nodule
To compare between surgical (hemi thyroidectomy and total thyroidectomy) and non-surgical (medical, ethanol injection,thermal ablation and laser photo coagulation) management of simple thyroid nodule regarding: Outcome of every…
- Trial name
- NCT04580199
- Testing
- thyroidectomy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mahmoud Fahd
Thyroid Gland Medullary Carcinoma
STAGE-MTC Trial Thyroid Lobectomy With Ipsilateral Central Neck Dissection
This clinical trial studies how well thyroid lobectomy with ipsilateral central neck dissection works to treat medullary thyroid cancer (MTC) in patients without a germline RET mutation (sporadic).
- Trial name
- NCT07612293
- Testing
- Biospecimen Collection, FDG-Positron Emission Tomography and Computed Tomography Scan, Ga-68 PET/CT Scan
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Hemithyroidectomy, Hypothyroidism
Higher Levothyroxine Requirements After Right-side Hemithyroidectomy
459 adult patients who received a hemithyroidectomy at the Department of General Surgery, Division of Endocrine Surgery and a follow-up visit (3-12 months post-surgery) at the thyroid outpatient clinic of the Department of…
- Trial name
- NCT04648722
- Testing
- Hemithyroidectomy
- Where
- Austria
- Volunteers
- 459 people
- Sponsor
- Medical University of Vienna
Thyroid Cancer, Papillary Thyroid Microcarcinoma
Multicenter Comparison of Thermal Ablation Versus Thyroid Lobectomy for Subcapsular Papillary Thyroid Microcarcinoma
To compare the clinical outcomes of Thermal ablation with those of thyroid lobectomy in patients with subcapsular papillary thyroid microcarcinoma.
- Trial name
- NCT06583057
- Testing
- Thermal ablation, Thyroid lobectomy
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Chinese PLA General Hospital
Hemithyroidectomy, Outpatient
Randomized Investigation of Thyroid Operation as Day Surgery
hemithyroidectomy as a outpatient procedure is performed in some countries, it has never been done a RCT whether it is feasible
- Conditions
- Hemithyroidectomy, Outpatient, Hemmorhage
- Trial name
- NCT02891252
- Testing
- outpatient procedure
- Where
- Denmark
- Volunteers
- 86 people
- Sponsor
- Zealand University Hospital
Thyroid Cancer, Surgery
Thyroxine Replacement Therapy After Lobectomy for Low-risk Papillary Thyroid Carcinoma
Papillary thyroid carcinoma (PTC) is the most common thyroid cancer and has a good prognosis.According to the 2015 American thyroid association (ATA) guidelines, no gross extrathyroidal extension and the number of pathological…
- Conditions
- Thyroid Cancer, Surgery, Recurrence
- Trial name
- NCT06087068
- Testing
- Thyroxine
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Papillary Thyroid Carcinoma, Thyroid Cancer
Cross-sectional Case and Control Study on Quality of Life, Appearance and Functions in PTC Via Different Surgical Approach
An observational cross-sectional case-control study on the postoperative quality of life (5 aspects, general quality of life, thyroid specific quality of life, scar appearance, voice and swallowing functions) of papillary thyroid…
- Trial name
- NCT05932121
- Testing
- Thyroid lobectomy via trans-axillary approach, Thyroid lobectomy via open approach
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Peking Union Medical College Hospital
Thyroid Lobectomy
A Randomized Control Trial for Patient Reported Outcomes and Safety in Outpatient Thyroid Lobectomy
To compare same-day discharge and overnight (or longer) observation practices and learn more about the differences in patient preferences, safety outcomes, and economic and resource impact
- Trial name
- NCT06085625
- Testing
- Pre-Surgery Survey, Post-Surgery Surveys
- Where
- United States
- Volunteers
- 224 people
- Sponsor
- M.D. Anderson Cancer Center
Recurrent Goiter
Thyroid Lobectomy With or Without Levothyroxine Treatment Postoperatively
The aim of this study was to compare the prevalence of recurrent nodular goiter in the contralateral thyroid lobe among patients after unilateral thyroid lobectomy for unilateral multinodular goiter receiving versus not receiving…
- Trial name
- NCT00941551
- Testing
- levothyroxine, no levothyroxine
- Where
- Poland
- Volunteers
- 150 people
- Sponsor
- Jagiellonian University
Autofluorescence, Thyroidectomy
Autofluorescence-guided Hemithyroidectomy in a Low-volume, Non-parathyroid Insitution: A Randomized Clinical Trial
Parathyroid damage and inadvertent excision unfortunately happens frequently in thyroid surgery. The use of near-infrared autofluorescence (NIRAF) intraoperatively, seems to be helpful in terms of parathyroid identification and…
- Conditions
- Autofluorescence, Thyroidectomy, Autotransplantation
- Trial name
- NCT05044351
- Testing
- Fluobeam LX, Conventional surgery without NIRAF assistance
- Where
- Denmark
- Volunteers
- 170 people
- Sponsor
- Regional Hospital West Jutland
Thyroid Neoplasms, Carcinoma, Papillary
Hybrid Endoscopic Hemithyroidectomy and Targeted Ablation for Bilateral Papillary Thyroid Carcinoma
This study evaluates a thyroid-function-preserving alternative to routine total thyroidectomy for bilateral papillary thyroid carcinoma (PTC).
- Trial name
- NCT07033572
- Testing
- Endoscopic Hemithyroidectomy with Central-Neck Dissection, Ultrasound-Guided Radiofrequency Ablation of Contralateral Nodule
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Fujian Medical University
Thyroid Cancer
Radiofrequency Ablation Versus Hemithyroidectomy for Small Thyroid Cancers
This is a multicenter randomized controlled trial including patients with small (<2 cm) suspected or confirmed thyroid cancers. Patients are included after informed consent and randomized to one of two treatments.
- Trial name
- NCT06796348
- Testing
- Radiofrequency ablation alone, Surgery
- Where
- Denmark
- Volunteers
- 88 people
- Sponsor
- University of Aarhus
Goiter, Hypothyroidism
ThyrOp: A Study of Individual Subclinical Hypothyroidism After Hemithyroidectomy for Benign Nontoxic Goiter
The hypothesis of the study is that among patients that do not develop overt hypothyroidism after hemithyroidectomy, weight gain is a clinical manifestation of a postoperatively lowered set point of thyroid function - even if the…
- Conditions
- Goiter, Hypothyroidism, Weight Gain
- Trial name
- ThyrOp (NCT01358136)
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Naestved Hospital
Thyroid Surgery, Inadvertent Parathyroidectomy
Use of the PTEye Device to Reduce Inadvertent Parathyroidectomy During Thyroid Surgery
Inadvertent Parathyroidectomy (IP) during thyroid surgery may lead to transient or permanent hypoparathyroidism and hypocalcemia, which represents significant morbidity.
- Conditions
- Thyroid Surgery, Inadvertent Parathyroidectomy, Enlarged Thyroid
- Trial name
- NCT06927245
- Testing
- PTeye Device
- Volunteers
- 25 people
- Sponsor
- ProMedica Health System
Well Differentiated Thyroid Carcinoma, Papillary Thyroid Cancer
The Incidence of Postoperative Re-stratification for Recurrence in Well-differentiated Thyroid Cancer - A Single Tertiary Israeli Center Experience
Background After diagnosing well-differentiated thyroid cancer (WDTC), careful assessment of the risk for disease-specific recurrence is essential for deciding between partial (low risk) and completion (high risk)…
- Trial name
- NCT04500925
- Testing
- UNILATERAL THYROIDECTOMY
- Volunteers
- 301 people
- Sponsor
- Tel-Aviv Sourasky Medical Center