Clinical trials: Thyroid Nodular Disease
Goiter, Nodular
Galectin 3 Dosage in Diagnosis of Nodular and Multinodular Goiter
The investigators will dose galectin 3 in plasma and water rinse of the needle aspiration biopsy in patients with thyroid nodules.
- Trial name
- Galectins (NCT01588288)
- Testing
- Galectin 3 dosage
- Where
- 2 sites in France
- Volunteers
- 193 people
- Sponsor
- University Hospital, Rouen
Nodular Goiter
rhTSH, Radioiodine Uptake and Goiter Reduction Following 131I Therapy in Patients With Benign Nontoxic Nodular Goiter
The study aims at clarifying (in a randomized, double-blinded design): 1. Whether stimulation with 0.1 mg rhTSH 24, 48 or 72 hours before induction of a 131I-tracer dosis increases the 131I uptake in patients with atoxic…
- Trial name
- NCT00275171
- Testing
- Recombinant human thyrotropin (Thyrogen), recombinant human TSH
- Where
- Denmark
- Volunteers
- 90 people
- Sponsor
- Steen Bonnema
Thyroid Neoplasms, Goiter, Nodular
Study of the Efficacy of Local Analgesia as an Adjunct to General Anesthesia in Thyroidectomy and Parathyroidectomy
We aim to study the effect of local anesthetic when used in conjunction with general anesthesia during thyroidectomy or parathyroidectomy.
- Conditions
- Thyroid Neoplasms, Goiter, Nodular, Thyroid Nodule, Graves' Disease
- Trial name
- NCT02205801
- Testing
- Superficial Cervical Plexus Block, Local Wound Infiltration, 0.9% saline
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Chicago
Thyroid Nodule, Thyroid Cancer
Pilot Study on Laser Ablation of Symptomatic Benign Thyroid Masses
This proposal is designed as a pilot study for the use of laser ablation for local control of symptomatic (e.g compressive) benign thyroid masses in 20 patients.
- Conditions
- Thyroid Nodule, Thyroid Cancer, Thyroid Neoplasms, Nodular Goiter
- Trial name
- NCT00615537
- Testing
- Laser Ablation of Thyroid Nodule
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- BioTex, Inc.
Nodular Goiter
Effect of Higher Doses of Remifentanil on Postoperative Pain in Patients Undergoing Thyroidectomy
Extensive clinical studies have shown that intraoperative infusion high dose of remifentanil (0.2ug/kg/min) induced postoperative hyperalgesia.
- Trial name
- NCT01761149
- Testing
- Remifentanil
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Central South University
Thyroid Nodular Disease
Microvascular Profiling of Nodules in the Thyroid Gland
The purpose of this study is to examine tiny blood vessels in different thyroid nodules using advanced ultrasound. In the long term, we hope this can help doctors better tell the difference between types of nodules and more…
- Trial name
- NCT07041307
- Where
- 2 sites in Denmark
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Thyroid Nodular Disease
Thyroid Fine Needle Biopsy and Impact on Pain and Diagnostic Adequacy
This randomized study compares patient pain and comfort during ultrasound-guided thyroid fine needle biopsy using 21-gauge versus 27-gauge needles. Patients with thyroid nodules were randomly assigned to one of two needle sizes.
- Trial name
- THY-BPSY (NCT07683039)
- Testing
- Thyroid fine needle biopsy with 21-gauge needle, Thyroid fine needle biopsy with 27-gauge needle
- Where
- Turkey (Türkiye)
- Volunteers
- 159 people
- Sponsor
- Izmir Ataturk Training and Research Hospital
Thyroid Nodule
Levothyroxine Treatment in Thyroid Benign Nodular Goiter
We will study the effect of taking eltroxin at different time, i.e. fasting or postprandial periods. We will also study the effect of levothyroxin treatment in Chinese people
- Trial name
- NCT00552253
- Testing
- Levothyroxin treatment
- Where
- Taiwan
- Volunteers
- 10 people
- Sponsor
- National Taiwan University Hospital
Toxic Nodular Goitre, Graves' Disease
Block-replacement Therapy During Radioiodine Therapy
Background: The use of radioactive iodine (131I) therapy as the definite cure of hyperthyroidism is widespread. According to a survey on the management of Graves' disease, thirty per cent of physicians prefer to render their…
- Trial name
- NCT00150124
- Testing
- MTZ+LT4, Methimazole
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Steen Bonnema
Toxic Nodular Goitre, Graves Disease
Antithyroid Drugs During Radioiodine Therapy
Background: The use of radioactive iodine (131I) therapy as the definite cure of hyperthyroidism is widespread. According to a survey on the management of Graves' disease, thirty per cent of physicians prefer to render their…
- Trial name
- NCT00150137
- Testing
- Methimazole
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- Odense University Hospital
Thyroid Nodular Disease
The Observer Variation of Shear Wave Elastography
Background: The main goal of diagnosing thyroid nodules is to differentiate the few malignant from the large background of benign lesion.
- Trial name
- NCT02022319
- Testing
- Ultrasonographic Shear Wave Elastography
- Where
- Denmark
- Volunteers
- 72 people
- Sponsor
- University of Aarhus
Incidence of Thyroid Cancer in Long Standing MNG
Risk of Malignancy in Endemic Long Standing Nodular Goitres: a Prospective Cohort Study
To determine the incidence of thyroid cancer in patients with long standing goitres presenting for surgery.
- Trial name
- NCT06405919
- Testing
- Histopathology
- Where
- Sudan
- Volunteers
- 160 people
- Sponsor
- University of Khartoum