Clinical trials: Thyroid Nodules
Thyroid Nodule, Thyroid Cancer
Clinical Validation of a Molecular Signature to Detect Cancer in Thyroid Nodules With Indeterminate Cytology
1. Principal objective: The primary objective of this study is to validate the diagnostic performance of a Dx15 molecular test based on molecular transcriptomic signatures previously identified in distincts cohorts of samples to…
- Trial name
- CITHY (NCT02225509)
- Testing
- FNA biopsy for thyroid nodule(s)
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Diaxonhit
Thyroid Nodule, Thyroid Cancer
NGS-based Thyroscan Genomic Classifier in the Diagnosis of Thyroid Nodules
The purpose of this study is to evaluate the accuracy of Thyroscan in the differential diagnosis of benign and malignant thyroid nodules with suspecious ultrasound features
- Trial name
- NCT05025046
- Testing
- Thyroscan
- Where
- 4 sites in China
- Volunteers
- 250 people
- Sponsor
- Rigen Biotech
Thyroid Nodule
Efficacy and Safety of Prunella Oral Liquid in the Treatment of Thyroid Nodules
A multicenter, prospective, randomized, double-blind, placebo-controlled clinical trial was designed to evaluate the efficacy and safety of Prunella oral liquid in patients with benign thyroid nodules, which belongs to the…
- Trial name
- ESPTTN (NCT06423235)
- Testing
- regular dose of JiRui® Prunella oral liquid, 2x regular dose of JiRui® Prunella oral liquid
- Where
- 22 sites in China
- Volunteers
- 234 people
- Sponsor
- Xintian Pharmaceutical
Thyroid Nodule, Thyroid Goiter
Prospective Evaluation of the Pulse Biosciences nPulse™ Vybrance™ Percutaneous Electrode System
The primary objective of this study is to reproduce in a multi-center study results obtained during the feasibility First-In-Human (FIH) study with Prof.
- Conditions
- Thyroid Nodule, Thyroid Goiter, Ablation
- Trial name
- PRECISE-BTN (NCT07287176)
- Testing
- nPulse Vybrance Percutaneous Electrode System
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- Pulse Biosciences, Inc.
Feasibility Study for Thyroid Indication
"Clinical Evaluation of Opto-Acoustic Tomography for Detection and Diagnostic Differentiation of Thyroid Nodules"
Thyroid Feasibility Study
- Trial name
- NCT03032198
- Testing
- Imagio OA/US
- Where
- 2 sites in United States
- Volunteers
- 37 people
- Sponsor
- Seno Medical Instruments Inc.
Thyroid Cancer, Thyroid Nodules
ctDNA in Patients With Thyroid Nodules
When the DNA inside of human cells undergoes certain alterations (mutations), the cells may develop into a cancer. The cancer cells may shed this DNA into the blood stream.
- Conditions
- Thyroid Cancer, Thyroid Nodules, Thyroid Adenoma, Thyroiditis
- Trial name
- NCT02778412
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Pathway Genomics
Thyroid Nodules, Thyroid Abnormalities
A Novel Ultrasound Probe for Thyroid Imaging and Machine Learning
The objective of the THYMAL 01 pilot study is to evaluate the Sound Blade Imaging System in subjects with benign thyroid nodules undergoing standard-of-care ultrasound imaging.
- Trial name
- THYMAL 01 (NCT07488585)
- Testing
- Thyroid ultrasound
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Sound Blade Medical Inc.
Non-malignant Thyroid Nodule
Registry - Use of a High Intensity Focused Ultrasound (HIFU) in Patients With Non-malignant Thyroid Nodules.
The purpose of this study is to evaluate thyroid nodule's volume, structure and vascularisation changes following HIFU therapy assessed by ultrasonography
- Trial name
- NCT02246504
- Testing
- HIFU treatment
- Where
- Bulgaria
- Volunteers
- 20 people
- Sponsor
- Theraclion
Non-malignant Thyroid Nodules
HIFU in Patients With Non-malignant Thyroid Nodules
Use of a high intensity focused ultrasound (HIFU) in patients with non-malignant thyroid nodules.
- Trial name
- NCT02258347
- Testing
- Echopulse
- Where
- Italy
- Volunteers
- 4 people
- Sponsor
- Theraclion
Benign Thyroid Nodules
Treatment of Benign Thyroid Nodules With FastScan HIFU
This study evaluates the efficacy of the HIFU for the treatment of benign thyroid nodules with the FastScan version using assessment of patient experience and adverse event reporting.
- Trial name
- NCT02491502
- Testing
- Echopulse
- Where
- Bulgaria
- Volunteers
- 36 people
- Sponsor
- Theraclion
Thyroid Nodule
Evaluation of the Thyroid Volume After Radiofrequency Ablation of Thyroid Nodules and Recurrent Thyroid
Thyroid nodules are among the common alterations of the thyroid. Depending on the detection method the prevalence is between 20% and 50%, whereas the incidence increases with improvement of ultrasonic technology.
- Trial name
- NCT03395925
- Testing
- Celon Pro Surge
- Where
- Germany
- Sponsor
- Olympus Surgical Technologies Europe
Tumor
Study of PXD101 Alone and in Combination With 5-Fluorouracil (5-FU) in Patients With Advanced Solid Tumors
This is a study to assess the combination of PXD101 and 5-Fluorouracil (5-FU)in patients with advanced solid tumors. The primary goal of the study is to understand the safety, anti-tumor activity, and how the study drug behaves…
- Trial name
- NCT00413322
- Testing
- belinostat, 5-Fluorouracil (5-FU)
- Where
- 3 sites in United States
- Volunteers
- 35 people
- Sponsor
- Valerio Therapeutics
Thyroid Nodule (Benign)
CellFX ® Percutaneous Electrode (PE) Treatment of Symptomatic Benign Thyroid Nodules
The objective of this clinical feasibility study is to evaluate initial clinical safety and device performance of the CellFX Percutaneous Electrode (PE) System for the treatment of symptomatic benign thyroid nodules.
- Trial name
- NCT06117085
- Testing
- CellFX® Percutaneous Electrode (PE) System
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Pulse Biosciences, Inc.
Thyroid Nodule
Percutaneous Laser Ablation in Benign Thyroid Nodules.Long Term Results
Thyroid nodule pathologies occur frequently and represent a clinical issue for the endocrinologists, surgeons, nuclear physicians as well as the general practitioners.
- Trial name
- NCT00858104
- Testing
- Percutaneous Laser Ablation
- Where
- 4 sites in Italy
- Volunteers
- 200 people
- Sponsor
- Elesta S.R.L.
Thyroid Nodule, Thyroid Cancer
Pilot Study on Laser Ablation of Symptomatic Benign Thyroid Masses
This proposal is designed as a pilot study for the use of laser ablation for local control of symptomatic (e.g compressive) benign thyroid masses in 20 patients.
- Conditions
- Thyroid Nodule, Thyroid Cancer, Thyroid Neoplasms, Nodular Goiter
- Trial name
- NCT00615537
- Testing
- Laser Ablation of Thyroid Nodule
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- BioTex, Inc.
Thyroid Nodule (Benign)
HIFU Treatment of Benign Thyroid Nodules
This clinical trial is to evaluate the effectiveness and the safety of high intensity focused ultrasound (HIFU) in the treatment of benign thyroid nodules.
- Trial name
- NCT04233398
- Testing
- Device: Echopulse (HIFU ablation)
- Volunteers
- 240 people
- Sponsor
- Theraclion
Autonomous Hyperfunctioning Thyroid Nodules
High Intensity Focused Ultrasound Device in Patients With Autonomous Hyperfunctioning Thyroid Nodules
The purpose of this study is to assess the efficacy and safety of High Intensity Focalized Ultrasound (HIFU) in the treatment for toxic Thyroids nodules
- Trial name
- NCT02169687
- Testing
- HIFU
- Where
- France
- Volunteers
- 2 people
- Sponsor
- Theraclion