Clinical trials: Thyroid Surgery
Thyroidectomy
Intraoperative Neuromonitoring of the Recurrent Laryngeal Nerve Versus Neurostimulation
The purpose of this study is to evaluate if intraoperative neuromonitoring associated to neurostimulation of recurrent laryngeal nerve reduce the rate of recurrent laryngeal palsy respect to neurostimulation alone.
- Trial name
- NCT01163045
- Testing
- thyroidectomy
- Where
- Italy
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Bologna
Thyroid Surgery
Effect of Cervical Block on Recurrent Laryngeal Nerve Monitoring During Thyroid Surgery
Non-inferiority study aimed to assess the impact of cervical block on recurrent laryngeal nerve monitoring during thyroid surgery Secondary outcomes will assess post-operative recovery, post-operative pain and post-operative…
- Trial name
- THYRODOUL2 (NCT04585126)
- Testing
- Intermediate cervical block
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Caen
Non-thyroidal Illness Syndrome
Peri-operative Oral Triiodothyronine Replacement Therapy to Decrease the Risk of Transient Atrial Fibrillation After Off-pump Coronary Artery Bypass Surgery
This study is planned to medicate oral T3(Liothyronine)to the patients who are planned to have OPCAB(off- pump coronary bypass graft surgery.
- Trial name
- NCT01153360
- Testing
- liothyronine sodium
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Yonsei University
Thyroid Associated Ophthalmopathy, Surgical Procedure, Unspecified
Evaluation of the Efficacy and Safety of 3D Printing for Orbital Surgery.
This is a multicentric, randomized, single-blinded clinical trial to evaluate the efficacy and safety of 3D printing for the planification and simulation of orbital decompression surgery for thyroid-associated orbitopathy.
- Trial name
- NCT04662190
- Testing
- 3D printing model/guide., Standard surgery
- Where
- Spain
- Volunteers
- 12 people
- Sponsor
- Althaia Xarxa Assistencial Universitària de Manresa
Graft Function
Intramuscular Injection of Mashed Parathyroid Tissue Into a Forearm During Thyroid Surgery to Prevent Permanent Postoperative Parathyroid Insufficiency (IMIPAT Study)
Parathyroid insufficiency is a common complication in thyroid surgery and occurs in 6.6 to 24%. Up to 4.4% suffer from permanent hypoparathyroidism requiring life-time substitution of calcium and vitamin D in order to maintain a…
- Trial name
- IMIPAT (NCT07516990)
- Testing
- Intramuscular injection of mashed parathyroid tissue into the brachioradial muscle during thyroid surgery
- Where
- 2 sites in Austria
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Hypoparathyroidism Postprocedural, Hypocalcemia
Near Infrared (NIR) Autofluorescence Image-guided Thyroid Surgery
The objective of this ongoing randomized controlled trial is to examine whether the use of intra-operative NIR(near infrared) camera can reduce the number of patients who experience transient or persistent hypoparathyroidism…
- Conditions
- Hypoparathyroidism Postprocedural, Hypocalcemia, Surgery--Complications
- Trial name
- NCT04193332
- Testing
- NIR optical imaging camera
- Where
- 2 sites in Denmark
- Volunteers
- 214 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Papillary Thyroid Cancer
Concordance of Molecular Classification Based on Fine Needle Biopsy (FNB) and Surgical Samples
The purpose of this study is to determine whether results from a fine needle biopsy are the same as results from a larger sample that is acquired from the surgical pathology using the Thyroid GuidePx® test in patients with…
- Trial name
- NCT06133374
- Where
- Canada
- Volunteers
- 130 people
- Sponsor
- University of Calgary
Thyroid Cancer
The Value of 68Ga-FAPI PET/CT in Detecting Recurrent and Metastatic Lesions in Patients with Thyroid Cancer After Surgery
This study aims to investigate the value of 68Ga-FAPI PET/CT in detecting recurrent and metastatic lesions in patients with thyroid cancer after surgery.
- Trial name
- NCT06800768
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Ruijin Hospital
Differentiated Thyroid Carcinoma (DTC)
Compare the Aesthetic Effect of Different Thyroidectomies
One hundred twenty female patients who underwent thyroidectomy were evenly distributed into three groups: conventional access (CA), aesthetic principles access (APA) and minimally invasive access (MIA).
- Trial name
- NCT03239769
- Testing
- thyroidectomy
- Volunteers
- 120 people
- Sponsor
- Peking University Cancer Hospital & Institute
Fentanyl, Dexmedetomidine
Fentanyl and Dexmedetomidine as Adjuvants to Bupivacaine in Ultrasound-guided Superficial Cervical Plexus Block in Thyroid Surgeries
This study aimed to compare the analgesic efficacy between fentanyl and dexmedetomidine as adjuvants to bupivacaine in ultrasound-guided superficial cervical plexus block for thyroid surgeries.
- Conditions
- Fentanyl, Dexmedetomidine, Adjuvants, Bupivacaine
- Trial name
- NCT07057739
- Testing
- Superficial cervical plexus block, Superficial cervical plexus block + Fentanyl, Superficial cervical plexus block + Dexmedetomidine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kafrelsheikh University
Quality of Life, Transoral Endoscopic Thyroidectomy
Comparison of Quality of Life Between Patients Underwent Transoral Endoscopic Thyroid Surgery and Conventional Surgery
The purpose of this study is to determine the quality of life of transoral endoscopic thyroidectomy compare with open thyroidectomy, Furthermore, postoperative complication will be assessed, also.
- Conditions
- Quality of Life, Transoral Endoscopic Thyroidectomy, Conventional Thyroidectomy
- Trial name
- NCT03048539
- Testing
- Transoral endoscopic thyroidectomy
- Where
- Thailand
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Khon Kaen University
Thyroid Diseases
The Feasibility and Safety of the TOETVA for Benign Thyroid Nodules
Thyroid surgery has been developed as a new technique for zero scar in surgery by applying transoral endoscopic thyroidectomy with sublingual approach.
- Trial name
- NCT03158961
- Testing
- Transoral endoscopic thyroidectomy vestibular approach
- Where
- Hong Kong
- Volunteers
- 10 people
- Sponsor
- The University of Hong Kong
Goiter
Subtotal Versus Total Thyroidectomy for Benign Goiter
The extent of thyroid resection in benign goiter is controversial. Potential advantages of TT over BST may include: one-stage removal of incidental thyroid cancer reported in up to 10% of operatively treated benign thyroid…
- Trial name
- NCT01273714
- Testing
- thyroid resection
- Where
- Poland
- Volunteers
- 8,006 people
- Sponsor
- Jagiellonian University
Ultrasound Therapy; Complications
Transcutaneous Laryngeal Ultrasound as an Alternative to Direct Flexible Laryngoscopy in Assessment of Vocal Cords
To evaluate the diagnostic value of ultrasound in the assessment of the vocal cords compared with direct flexible laryngoscopy
- Trial name
- NCT06161467
- Testing
- Ultrasound devices
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Assiut University
Hypocalcemia
Parathyroid Autofluorescence Visualization in Thyroid Surgery: Impact on Postoperative Hypocalcemia
This Multicenter, Randomized Controlled Trial evaluates the clinical impact of parathyroid autofluorescence visualization using near infrared light (NIR) during total thyroidectomy (TT).
- Trial name
- NCT02892253
- Testing
- Near Infrared Camera (NIR)
- Where
- 3 sites in France
- Volunteers
- 241 people
- Sponsor
- Hôpital Européen Marseille
Whey Protein, Thyroid Neoplasms
Whey Protein and Carbohydrates in ERAS for Recovery After Thyroidectomy: A Cohort Study
Exploring the effects of whey protein combined with carbohydrates in an Enhanced Recovery After Surgery (ERAS) protocol on the postoperative recovery of thyroid cancer patients undergoing lateral neck dissection, aiming to…
- Conditions
- Whey Protein, Thyroid Neoplasms, Neck Dislocation, Enhanced Recovery After Surgery
- Trial name
- NCT06607965
- Testing
- Whey Protein and Carbohydrates
- Where
- China
- Volunteers
- 127 people
- Sponsor
- Chongqing General Hospital
Anesthesia Intubation Complication, Tracheal Disease
The Effect of Prophylactic Ketorolac on Sore Throat After Thyroid Surgery
Sore throat is one of most frequent complaints related to general anesthesia with tracheal intubation. Although sore throat is regarded as a minor and short-lasting discomfort after surgery, its incidence and intensity in high…
- Trial name
- NCT02039427
- Testing
- Ketorolac, Dexamethasone
- Where
- South Korea
- Volunteers
- 192 people
- Sponsor
- Yeungnam University College of Medicine
Thyroid Node, Indeterminate Cytology
Diagnostic Value of Molecular Cytological Analysis (CMA) and Shear Wave Elastography ShearWave (SWE) in Patients With a Thyroid Nodule With Indeterminate Cytology: Feasibility Study
The purpose of the study is to investigate the contribution of molecular cytological analysis (CMA) and shear wave elastography ShearWave (SWE) in the diagnosis of nodules with indeterminate cytology (IC)
- Conditions
- Thyroid Node, Indeterminate Cytology, Surgery Indication
- Trial name
- SWEETMAC (NCT01880203)
- Testing
- aspiration in thyroid node for Molecular Cytogenetic Analysis.
- Where
- 4 sites in France
- Volunteers
- 140 people
- Sponsor
- Centre Francois Baclesse
Papillary Thyroid Microcarcinoma
A Multicenter Trial of Radiofrequency Ablation vs. Surgery as Treatment of Papillary Thyroid Microcarcinoma.
The treatment of Papillary Thyroid Microcarcinoma (PTMC) nowadays varies among physicians, surgeons and radiologist. The recently published articles show that the prognosis of PTMC by different means of treatment strategies tends…
- Trial name
- NCT03808779
- Testing
- Radiofrequency Ablation, Conventional Surgery
- Where
- 3 sites in China, Ukraine
- Volunteers
- 200 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Recurrent Laryngeal Nerve Palsy, Risk Factors of Vocal Cord Palsy
Predisection Risk Factors for Vocal Cord Palsy After Total Thyroid Surgery
In patients undergoing total thyroidectomy, intraoperative nerve monitoring according to the International Standards Guideline Statement may detect nerves more susceptible to injury.
- Conditions
- Recurrent Laryngeal Nerve Palsy, Risk Factors of Vocal Cord Palsy, Neuromonitoring in Thyroid Surgery
- Trial name
- NCT04986592
- Volunteers
- 106 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute