Clinical trials: Thyroidectomy, open to volunteers
Total Thyroidectomy
Impact of Manual Therapy on Laryngeal Function Following Total Thyroidectomy
In this clinical trial, the investigators are seeking to learn if a course of voice therapy, including neck massage, stretches and pain science education in addition to voice exercise and scar massage will effectively treatment…
- Trial name
- Man Total Thy (NCT06383091)
- Testing
- Anterior Neck Manual Therapy, Pain Neuroscience Education, Neck Stretches
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Johns Hopkins University
Post-Surgical Hypoparathyroidism
Risk Factors for Hypoparathyroidism Following Thyroidectomy
The goal of this observational study is to identify the risk factors for post-thyroidectomy hypoparathyroidism in Estonia and to determine whether the magnesium level plays a significant role in the development of…
- Trial name
- NCT07582562
- Where
- 2 sites in Estonia
- Volunteers
- 300 people
- Sponsor
- Tartu University Hospital
Thyroid Diseases, Wound Healing
Safety and Efficacy of NTP in Thyroid Surgery: Pilot Study on Morbidity Prevention and Adjuvant Oncological Control
The goal of this clinical trial is to evaluate the therapeutic efficacy and safety of non-thermal plasma (NTP) as an adjuvant treatment for surgical bed decontamination and accelerated tissue repair in patients undergoing total…
- Conditions
- Thyroid Diseases, Wound Healing, Thyroidectomy, Surgical Wound Infection
- Trial name
- NCT07382973
- Testing
- Atmospheric Pressure Non-Thermal Plasma, Standard Surgical Wound Care Protocol
- Where
- Mexico
- Volunteers
- 26 people
- Sponsor
- National Institute of Nuclear Research - Mexico
Total Thyroidectomy, Hyperthyroidism
Evaluation of Levothyroxine Replacement Therapy After Total Thyroidectomy Using a Smart Wristband
The goal of this observational study is to determine whether nighttime heart rate and heart rhythm data collected by a smart wristband can identify under- or over-replacement with levothyroxine before the routine 1-month thyroid…
- Conditions
- Total Thyroidectomy, Hyperthyroidism, Hypothyroidism
- Trial name
- SMART-THY (NCT07733375)
- Testing
- Xiomi Smart Band 10
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Yeditepe University Hospital
Thyroidectomy, Cervical Plexus Block
The Effect of Bilateral Intermediate Cervical Plexus Block on the Surgical Stress Response Following Total Thyroidectomy
Total thyroidectomy triggers a systemic surgical stress response involving neuroendocrine and inflammatory pathways. Ultrasound-guided bilateral intermediate cervical plexus block (BICPB) is commonly utilized for postoperative…
- Conditions
- Thyroidectomy, Cervical Plexus Block, Surgical Stress Response
- Trial name
- NCT07740460
- Testing
- Ultrasound-Guided Bilateral Intermediate Cervical Plexus Block Using 0,25% Levobupivacaine
- Volunteers
- 48 people
- Sponsor
- University Hospital Dubrava
Differentiated Thyroid Cancer (DTC), Papillary Thyroid Carcinoma
Serum Treg/Th17-Related Cytokines and Systemic Inflammatory Indices in Differentiated Thyroid Cancer
This study measures circulating immune-signaling molecules before thyroid surgery to determine whether they differ between patients whose thyroid nodule proves to be a differentiated thyroid carcinoma and patients whose nodule…
- Conditions
- Differentiated Thyroid Cancer (DTC), Papillary Thyroid Carcinoma, Thyroid Cancer, Thyroid Nodule
- Trial name
- THINC (NCT07907432)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Marmara University
Thyroid Diseases, Recurrent Laryngeal Nerve Injury
Endotracheal Tube Versus Transcartilage Needle Electrodes for Nerve Monitoring in Thyroid Surgery
Intraoperative neuromonitoring of the recurrent laryngeal nerve during thyroidectomy is most commonly performed with surface electrodes embedded in the endotracheal tube (ETT).
- Conditions
- Thyroid Diseases, Recurrent Laryngeal Nerve Injury, Vocal Cord Paralysis, Thyroid Nodule
- Trial name
- TRANSCOMP (NCT07902349)
- Testing
- Transcartilage needle electrode recording, Endotracheal tube surface electrode recording
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Marmara University
Total Thyroidectomy
Impact of Travel Neck Pillow Use on Neck Comfort and Mobility After Thyroidectomy
This study aims to evaluate the effectiveness of U-shaped travel neck pillow use in improving cervical comfort, reducing neck pain and stiffness, and enhancing cervical range of motion in adults undergoing total thyroidectomy…
- Trial name
- TiNeCoM (NCT06909513)
- Testing
- U-shaped Travel Neck Pillow
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- TC Erciyes University
Carpal Tunnel Surgery
Study of Transaxillary Robotic Thyroidectomy Versus Standard Open Thyroidectomy: Prospective, Comparative Single-Center Study
The aim of our study is to evaluate the two surgical approaches, standard thyroidectomy and robotic thyroidectomy, in terms of postoperative pain management, scar quality, quality of life, as well as the occurrence of…
- Trial name
- CARTO (NCT06693258)
- Testing
- thyroidectomy by robotic surgery via axillary approach, thyroidectomy by standard conventional surgery
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Clinique Bizet
Throid Surgery, Airway Complication of Anaesthesia
Comparison of the Effects of Total Intravenous Anaesthesia With Target-Controlled Infusion (TCI) and Inhalation Anaesthesia on Airway Complications During Extubation and in the Early Postoperative Period in Thyroidectomy Surgery
Thyroid surgery is one of the most complex operations in the head and neck region due to its close relationship with anatomical structures and the high risk of recurrent laryngeal nerve injury.
- Conditions
- Throid Surgery, Airway Complication of Anaesthesia, Coughing Responses at Tracheal Extubation, Laryngospasm on Emergence
- Trial name
- NCT07325669
- Testing
- tıva
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- dilara gocmen
Surgical Stress Response, Total Thyroidectomy
The Association Between Bilateral Intermediate Cervical Plexus Block and Salivary Biomarkers of Surgical Stress Response Following Total Thyroidectomy
The aim of this study is to evaluate how an ultrasound-guided bilateral intermediate cervical plexus block affects the surgical stress response in individuals undergoing total thyroidectomy.
- Conditions
- Surgical Stress Response, Total Thyroidectomy, Saliva Collection, Cervical Plexus Block
- Trial name
- NCT07721818
- Testing
- Ultrasound guided bilateral intermediate cervical plexus block
- Volunteers
- 48 people
- Sponsor
- University Hospital Dubrava
Hypocalcemia, Hypoparathyroidism
NIRAF-Guided Parathyroid Identification During Thyroidectomy
This study evaluates whether a wearable near-infrared autofluorescence (NIRAF) imaging system can help surgeons identify and preserve parathyroid glands during thyroid surgery.
- Conditions
- Hypocalcemia, Hypoparathyroidism, Thyroid Diseases, Goiter, Nodular
- Trial name
- NCT07617584
- Testing
- Wearable Near-Infrared Autofluorescence Imaging System
- Where
- North Macedonia
- Volunteers
- 280 people
- Sponsor
- Ss. Cyril and Methodius University of Skopje
Thyroid Diseases, Ambulation Time
Comparison of Post-operative Outcomes Between ERAS Protocol and Non-ERAS Local Regimen in Patients Undergoing Thyroidectomy
Patients undergoing thyroidectomy in hospital setup will be compared by applying ERAS protocol to one group and non ERAS local regimen to other group.
- Conditions
- Thyroid Diseases, Ambulation Time, Hospital Stay
- Trial name
- NCT07915960
- Testing
- ERAS protocol, Non ERAS local regimen
- Where
- Pakistan
- Volunteers
- 96 people
- Sponsor
- Allied Hospital Faisalabad
Thyroid Cancer, Thyroid and Parathyroid Surgery
The Association Between Bilateral Intermediate Cervical Plexus Block During Total Thyroidectomy and Surgical Stress Response
The aim of this study is to determine the impact of ultrasound-guided bilateral intermediate cervical plexus block on the surgical stress response in patients undergoing total thyroidectomy, as measured by the concentration of…
- Conditions
- Thyroid Cancer, Thyroid and Parathyroid Surgery, Hyperthyreosis and Goiter, Surgical Stress Response
- Trial name
- NCT07600580
- Testing
- bilateral ultrasound guided intermediate cervical plexus block with 0,25% levobupivacaine
- Where
- Croatia
- Volunteers
- 48 people
- Sponsor
- University Hospital Dubrava
Post-Thyroidectomy Hypoparathyroidism
Psychological Problems in Post Thyroidectomy Patients
Quality of life (QoL) refers to perceived well-being, and encompasses the evaluation of physical health, and physical, social, and psychological functioning .
- Trial name
- NCT06929104
- Testing
- No intervention
- Volunteers
- 127 people
- Sponsor
- Assiut University
Thyroid Neoplasms, Hyperparathyroidism
Dual-Channel Near-Infrared Autofluorescence Imaging and AI Analysis to Locate Parathyroid Glands (PTFinder)
This study tests PTFinder, a dual-camera system that makes parathyroid glands glow on screen by capturing their natural near-infrared autofluorescence.
- Conditions
- Thyroid Neoplasms, Hyperparathyroidism, Parathyroid Gland
- Trial name
- PTFinder (NCT07010380)
- Testing
- PTFinder Dual-Channel NIR Autofluorescence Imaging System, Offline Machine-Learning Algorithm (PTFinder-AI Beta)
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Bo Wang,MD
Thyroid Surgeries, Intraoperative Analgesic Use
qCON/qNOX-Guided Anesthesia in Patients Undergoing Thyroidectomy Surgery
The aim of this study is to evaluate the effect of using the non-invasive Conox monitor on intraoperative opioid consumption. Additionally, the study aims to assess the impact of Conox monitoring on recovery time, postoperative…
- Conditions
- Thyroid Surgeries, Intraoperative Analgesic Use, Anesthesia Depth Monitoring
- Trial name
- NCT07445659
- Testing
- Connox EEG Monitoring, standard anesthesia management
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Kayseri City Hospital
Thyroidectomy, Coughing Reflex
The Effect of Esketamine on Cough Reflex During Tracheal Extubation in Patients Undergoing Open Thyroid Surgery
This study intends to conduct a prospective randomized controlled trial to implement esketamine-assisted anesthesia in patients undergoing open thyroidectomy, in order to observe the effect of esketamine on coughing during…
- Trial name
- NCT07625826
- Testing
- Esketamine, Normal Saline
- Where
- China
- Volunteers
- 136 people
- Sponsor
- The Second Hospital of Anhui Medical University
Goiter, Thyroid Disease
Dysphagia After Thyroidectomy
The goal of this observational study is to develop a questionnaire for measuring swallowing and throat discomfort symptoms in patients with goiter or thyroidectomy, which complies with the model of Rasch and which satisfies the…
- Trial name
- DYSPHATHYR (NCT06296420)
- Where
- Italy
- Volunteers
- 420 people
- Sponsor
- Istituto Auxologico Italiano
Post-Thyroidectomy Hypoparathyroidism Treatment
Calcium Replacement Therapy in Postoperative Hypoparathyroidism
The goal of this clinical trial is to evaluate whether a lower-dose calcium replacement therapy is non-inferior to a higher-dose regimen in preventing symptomatic hypoparathyroidism in patients following thyroidectomy.
- Trial name
- NCT07577570
- Testing
- Calcium carbonate 1250 mg (500 mg elemental calcium) twice a day, Calcium carbonate 1250 mg (500 mg elemental calcium) 4 times a day
- Where
- 2 sites in Estonia
- Volunteers
- 50 people
- Sponsor
- Tartu University Hospital