Clinical trials: Tibial Fracture
Tibial Plateau Fracture, Pain, Postoperative
Duloxetine Tibial Plateau
The purpose of this study is to determine if Duloxetine provides effective pain management for adult patients (18 or older) undergoing tibial plateau surgery.
- Trial name
- NCT04639011
- Testing
- Duloxetine, Standard of care (SOC) for tibial plateau surgery
- Where
- 2 sites in United States
- Sponsor
- Boston Medical Center
Fracture Non Union, Infection
Antibiotic Loaded Calcium Sulfate RCT
This is a multi-centered, prospective, randomized controlled trial comparing current standard of care for defect management to placement of antibiotic loaded Stimulan as a bone void filler in patients undergoing treatment of…
- Trial name
- NCT03875963
- Testing
- Antibiotic loaded bone filler
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Proximal Humeral Fracture, Proximal Tibia Fractures
PMCF Study on the Safety, Performance and Clinical Benefits Data of the Zimmer® Plates and Screws System
The study is a monocentric, retro- and prospective, non-randomized, non-controlled and consecutive series post-market study. The purpose of this study is to confirm safety, performance and clinical benefits of the Zimmer® Plates…
- Conditions
- Proximal Humeral Fracture, Proximal Tibia Fractures, Diaphyseal Fracture
- Trial name
- NCT05215613
- Where
- Italy
- Volunteers
- 57 people
- Sponsor
- Zimmer Biomet
Musculoskeletal Injury
NSAID Use and Healing After Tibia Fractures and Achilles Tendon Ruptures
Rationale: The Emergency Department (ED) typically serves as the front line for patients with acute fractures and tendon ruptures. Pain control for these patients is an essential task of the ED physician.
- Trial name
- NCT03880981
- Testing
- Ibuprofen 600 mg, Acetaminophen
- Volunteers
- 456 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Orthopedic Disorders, Tibial Fractures
Reliability of Sensor Spacing for NIRS in Traumatic Tibia Fractures
This is a study intended to evaluate a non-invasive device that uses light to measure the amount of oxygen in the muscles of injured and non-injured legs in specific situations.
- Trial name
- NCT02301832
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Emory University
Tibial Plateau Fracture
Efficacy of the Use of 3D Printing Models in the Treatment of Tibial Plateau Fractures: a Randomized Clinical Trial
TIBIA3D is a randomized, open and prospective clinical trail that evaluates the use of preoperative 3D printing in the surgical treatment of patients with tibial plateau fractures
- Trial name
- NCT05571449
- Testing
- Open reduction and internal fixation, Standard osteosynthesis planning, 3-D model osteosynthesis planning
- Where
- Spain
- Volunteers
- 35 people
- Sponsor
- Pedro-José Torrijos-Garrido
Pilon Fracture of Tibia
Pilon Fracture Reduction and Functional Outcome
This prospective case series will essentially examine the influence of reduction quality on the primary functional outcome (as assessed using the FAAM) of patients with pilon fractures treated with plate fixation.
- Trial name
- NCT01316289
- Where
- 9 sites in United States, Austria and 2 more
- Volunteers
- 117 people
- Sponsor
- AO Clinical Investigation and Publishing Documentation
Tibia Fracture
OIF/β-TCP in Patients With Open Tibial Fractures in Need of Bone Grafting
A prospective, randomized, evaluator-blinded, controlled study for subjects with open tibial fractures classified as Gustilo type II, IIIA or IIIB (see Appendix 1) who will receive bone graft implantation for the potential of…
- Trial name
- NCT04960722
- Testing
- OIF/β-TCP
- Where
- Taiwan
- Volunteers
- 35 people
- Sponsor
- BioGend Therapeutics Co.Ltd
Broken Leg
Tibial Shaft Nailing Treated With Suprapatellar Nailing
The goal of this project is to determine the incidence of intra-articular knee pathology following tibial shaft fractures as evaluated by intraoperative knee aspiration and physical exam, and to evaluate for chondral injuries…
- Trial name
- NCT02510339
- Testing
- Observation
- Volunteers
- 16 people
- Sponsor
- Orlando Health, Inc.
Pain, Postoperative, Fracture, Ankle
Auricular Acupuncture as Part of Multimodal Analgesia After Lower Leg Fracture
The purpose is to find out if incorporation of an intraoperative electro auricular acupuncture protocol when added to a standard multimodal analgesic regimen for patients undergoing surgery to repair lower leg fracture under…
- Conditions
- Pain, Postoperative, Fracture, Ankle, Pilon Fracture of Tibia, Foot Fracture
- Trial name
- NCT05984433
- Testing
- Auricular acupuncture
- Where
- United States
- Sponsor
- Baylor College of Medicine
Tibial Fracture
Study to Assess the Efficacy and Safety of Allogeneic Osteoblastic Cells (ALLOB®) Single Implantation in Tibial Fracture
Although the majority of tibial fractures heal normally, some fractures may not heal within the usual time frame and is known as delayed bone healing within 4 to 6 months and absence of bone healing within 9 to 12 months in the…
- Trial name
- ALLOB-TF2 (NCT04432389)
- Testing
- ALLOB
- Where
- 39 sites in Belgium, Czechia and 5 more
- Volunteers
- 178 people
- Sponsor
- Bone Therapeutics S.A
Open Tibia Fracture, Open Dislocation of Ankle
Accelerated Flap Coverage Versus Standard Timing in the Treatment of Severe Lower Extremity Musculoskeletal Injuries
The goal of this randomized controlled trial is to determine if accelerated flap coverage compared to standard flap coverage timing leads to improved infection-related complications in patients with open fractures and/or…
- Conditions
- Open Tibia Fracture, Open Dislocation of Ankle, Extremity Fracture Lower, Extremity Injuries Lower
- Trial name
- FLAP ATTACK (NCT07828613)
- Testing
- Accelerated Flap Coverage Surgery, Standard of Care Flap Timing
- Where
- 31 sites in United States
- Volunteers
- 356 people
- Sponsor
- Johns Hopkins University
Tibial Fractures
Pulsed Electromagnetic Field (PEMF) Stimulation for Tibia Fractures
Fractures of the tibial shaft (diaphysis) are some of the most common long bone fractures. They most frequently occur in males less than 40 years of age.
- Trial name
- NCT00127725
- Testing
- Pulsed electromagnetic field stimulation
- Where
- 5 sites in Australia
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Sydney South West Area Health Service
Surgery--Complications, Tibia Fracture
Immediate Mobilization After Plate Osteosynthesis of Proximal Tibial Fractures - A Cohort Study
The purpose of this study is to investigate if immediate mobilization with weight bearing as tolerated following surgery with plates and screws after a fracture of the shinbone near the knee is possible without increased risk.
- Conditions
- Surgery--Complications, Tibia Fracture, Early Ambulation
- Trial name
- IMOP (NCT03314623)
- Testing
- Weight bearing as tolerated
- Where
- Denmark
- Volunteers
- 70 people
- Sponsor
- Slagelse Hospital
Open Tibia Fracture
Low-cost Negative Pressure Wound Therapy vs Standard Dressings for Gustilo IIIb Tibial Fractures (Bukavu Pilot RCT)
Negative-pressure wound therapy (NPWT) is widely used in the management of acute and chronic wounds, but commercial systems are costly and may be inaccessible in low-resource settings.
- Trial name
- BukavuNPWTRC (NCT07790991)
- Testing
- intervention2: standard wound dressing, Intervention1: Low-cost NPWT
- Where
- 2 sites in Democratic Republic of the Congo
- Volunteers
- 66 people
- Sponsor
- Université Catholique de Bukavu
Pediatric Fractures
Value of Sonographic Diagnosis of Toddler's Fracture of the Tibia
This fracture of the distal tibia occurs in 1 to 4 year-old-children. Timely diagnosis is important, because it obviates the need for investigations to archive adequate treatment as well as to prevent unnecessary immobilization.
- Trial name
- NCT02077855
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Osteomyelitis Tibia, Tibial Fractures
Prophylactic Antibiotic Coated Nail to Prevent Infection: A Clinical Trial
This prospective randomized clinical trial will compare outcomes between patients treated primarily with a prophylactic antibiotic coated nail and those treated with traditional standard of care intramedullary (IM) nailing.
- Conditions
- Osteomyelitis Tibia, Tibial Fractures, Open Tibia Fracture
- Trial name
- NCT05421741
- Testing
- Antibiotic coated intramedullary Nail, Standard Intramedullary Nail
- Where
- 15 sites in United States
- Volunteers
- 242 people
- Sponsor
- Wake Forest University Health Sciences
Wrist Injury, Tibial Fracture
Pilot Study Comparing Diagnostic Imaging Versus Tomosynthesis in Detection of Hip, Wrist or Tibia Injury
To acquire and build a library of image sets to determine if Fuji's TOMO imaging device can replace or compliment current imaging standards to assess patients with hip, wrist or tibia injuries.
- Conditions
- Wrist Injury, Tibial Fracture, Hip Injury
- Trial name
- TOMO (NCT01927575)
- Testing
- Standard X-Ray + CT, Standard X-Ray + MRI, TOMO
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Fujifilm Medical Systems USA, Inc.
Tibial Shaft Fractures
Primary Dynamization Versus Standard Interlocking Intramedullary Nail in Treatment of Tibial Shaft Fractures in Adults
fracture shfat tibia in adults treated by interlocking intramedullary nail by primary dynamic versus standard ways
- Trial name
- NCT06147219
- Testing
- interlocking intramedullary tibial nail
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sohag University
Femur Shaft Fracture, Tibia Fractures
Assessing Bone Fracture Healing Effect of Almonds
Femur and tibia shaft fractures are common after trauma with a burden of 5% and 20% respectively. Clinicians recommend costly bone strengthening drugs/supplements while treating bone fractures.
- Conditions
- Femur Shaft Fracture, Tibia Fractures, Vitamin D, Sweet Almonds
- Trial name
- AFHEA (NCT07153302)
- Testing
- Prunus dulcis (sweet almonds)
- Where
- Pakistan
- Volunteers
- 136 people
- Sponsor
- Aga Khan University Hospital, Pakistan