Clinical trials: Tic Disorders, open to volunteers
Tic Disorder
Teen and Adult Tic TMS Study
This project investigates safety, tolerability, and efficacy signals of accelerated continuous theta burst stimulation (cTBS), a form of inhibitory repetitive transcranial magnetic stimulation (rTMS), for patients with Tourette…
- Trial name
- NCT07839377
- Testing
- cTBS (accelerated continuous theta burst stimulation)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, San Francisco
Obsessive - Compulsive Disorder, Tic Disorder, Chronic Motor or Vocal
Integrating Exposure and Response Prevention and Habit Reversal Techniques to Treat a Tourettic Subtype of Obsessive-Compulsive Disorder (Tourettic OCD)
Obsessive-Compulsive Disorder and Tic Disorders frequently co-occur, and a subgroup of patients - those with a Tourettic Subtype of OCD (TOCD) - present with concurrent obsessive-compulsive and tic symptoms.
- Conditions
- Obsessive - Compulsive Disorder, Tic Disorder, Chronic Motor or Vocal, Tic Disorders, Tic Disorder, Combined Vocal and Multiple Motor
- Trial name
- TORCH (NCT07725926)
- Testing
- Exposure and Response Prevention (ERP), Habit Reversal Training (HbRT, Psychoeducation and Supportive Intervention
- Where
- 2 sites in United Kingdom
- Volunteers
- 40 people
- Sponsor
- University College London Hospitals
Parkinson's Disease
Deep Brain Stimulation Therapy in Movement Disorders
Background: In deep brain stimulation (DBS), a device called a neurostimulator is placed in the chest. It is attached to wires in parts of the brain that affect movement.
- Trial name
- NCT02119611
- Testing
- Deep Brain Stimulation management
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Tic Disorders
Mobile App-assisted Behavioral Treatment in Children and Adolescents With Tics
Chronic tic disorders are neurodevelopmental disorders affecting 0.5-1% of children and adolescents. Tics present as sudden, rapid, repetitive non-rhythmic movements or vocalizations or a combination.
- Trial name
- NCT05390268
- Testing
- Mobile app-assisted behavioral treatment, Mobile app-assisted psychoeducation
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Aarhus University Hospital
Dystonia, Epilepsy in Children
A Multicenter Pediatric Deep Brain Stimulation Registry
There is limited data on outcomes for children who have undergone deep brain stimulation (DBS) for movement disorders, and individual centers performing this surgery often lack sufficient cases to power research studies…
- Conditions
- Dystonia, Epilepsy in Children, Cerebral Palsy, Tourette Syndrome
- Trial name
- DBS-R (NCT06585618)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Boston Children's Hospital
Tourette Syndrome
Characterising Sleep Disorders in Children With Tourette Syndrome
Healthy sleep is essential for a young person's growth, development, and wellbeing. It is estimated that up to 80% of young people with Tourette Syndrome experience sleep difficulties.
- Trial name
- NCT07450079
- Volunteers
- 34 people
- Sponsor
- Steffi Baker
Tic Disorder, Provisional Tic Disorder
Let It TiC in Childhood Provisional Eye Tic
Clarify the effectiveness and safety of "Reduced-Attention Intervention Therapy" in treating children with Provisional tic disorder （PTD） who mainly exhibit abnormal blinking behavior
- Trial name
- LETITTIC (NCT07838428)
- Testing
- Reducing Attentional Interventions Therapy Treatment, Continue with the previous treatment plan
- Where
- China
- Volunteers
- 134 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Tourette Syndrome
Epidemiology of Assertiveness and Emotion Management Disorders in People With Tourette's Syndrome
The goal of this study is to evaluate the proportion of assertiveness difficulties in Tourette syndrome. Participants will complete several e-questionnaires (on assertiveness, Tourette severity, quality of life, self-esteem and…
- Trial name
- AFFIRMATICS (NCT06136572)
- Testing
- Rathus Assertiveness scale
- Where
- France
- Volunteers
- 350 people
- Sponsor
- University Hospital, Clermont-Ferrand
Tourette Syndrome
Strengthening Tourette Treatment OPtions Using TMS to Improve CBIT, a Double-blind, Randomized, Controlled Study
This pilot study will investigate the clinical and neurophysiological effects of repetitive transcranial magnetic stimulation (rTMS) followed by comprehensive behavioral intervention for tics (CBIT) in adult patients with…
- Trial name
- STOP-TIC (NCT05705999)
- Testing
- transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- West Virginia University
Tourette's Disorder, Insomnia
Forehead Temperature-Regulating Therapy for Insomnia in Adults With Tourette's Disorder
The primary aim of the present research project is to investigate the preliminary effects of four weeks of forehead temperature-regulating therapy on insomnia in adults with Tourette's disorder and co-occurring insomnia disorder.
- Trial name
- NCT05499741
- Testing
- Forehead Temperature-Regulating Therapy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of California, Los Angeles
Tic Disorders
Adult Tic Disorders Registry
The purpose of this study is to develop the adult tic disorders registry in order to characterize the relationship between tic severity and tic-related impairment in women compared to men with tic disorders.
- Trial name
- RegisTICs (NCT05090943)
- Testing
- QOL to be completed by the participant
- Where
- 7 sites in France
- Volunteers
- 450 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris