Clinical trials: Tick Fever
Relapsing Fever, Tick-Borne
Postexposure Prophylaxis With Single Dose Doxycycline for the Prevention of Tick-borne Relapsing Fever
The goal of this clinical trial is to compare standard treatment (5 days of doxycycline) vs single dose doxycycline for the prevention of tick-borne relapsing fever in soldiers who found bite marks on their bodies after an…
- Trial name
- NCT06045481
- Testing
- administration of single dose of doxycycline
- Volunteers
- 526 people, healthy volunteers welcome
- Sponsor
- Medical Corps, Israel Defense Force
Relapsing Fever, Tick-borne, Jarisch Herxheimer Reaction
Post Exposure Treatment With Doxycycline for the Prevention of Relapsing Fever
Abstract Background Tick-Borne Relapsing Fever (TBRF) is an acute febrile illness. In Israel, TBRF is caused by Borrelia persica and is transmitted by Ornithodoros tholozani ticks.
- Trial name
- NCT00237016
- Testing
- doxycycline treatment
- Where
- Israel
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Medical Corps, Israel Defense Force
Dengue, Chikungunya
Risk Assessment of Community Spread of Multiple Endemic Infectious Diseases in a One Health Perspective
RACSMEI addresses the high burden of infectious diseases in low- and middle-income countries, including Cambodia, where limited surveillance and laboratory capacity often obscure etiologies and transmission dynamics.
- Conditions
- Dengue, Chikungunya, Zika Virus Infection, Japanese Encephalitis
- Trial name
- RACSMEI (NCT07358910)
- Where
- Cambodia
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur du Cambodge
Rickettsioses
Laboratory Diagnosis of of Rickettsial and Rickettsia-like Diseases
The low confirmed rickettsioses cases rate may indicate the presence of rickettsiosis other than scrub typhus, murine typhus, and Q fever.
- Trial name
- NCT01137175
- Where
- Taiwan
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Tularaemia
Phase II Tularemia Vaccine Comparison
The purpose of this study is to compare 2 experimental vaccines that could provide protection from the disease, tularemia. This research will compare the ability of the vaccines to cause the body to develop an immune (protective)…
- Trial name
- NCT01150695
- Testing
- Undiluted Francisella tularensis live attenuated vaccine
- Where
- 5 sites in United States
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Crimean Congo Hemorrhagic Fever
Study to Evaluate Safety and Immunogenicity of DNA Vaccine N-pVAX1 Against Crimean Congo Hemorrhagic Fever
This First-in-human dose-escalation vaccine phase I study aims to evaluate safety and reactogenicity of the investigational vaccine N-pVAX1, against Crimean Congo Hemorrhagic Fever, delivered by in vivo EP given as three im doses…
- Trial name
- CCHF-NP-1 (NCT06684431)
- Testing
- N-pVAX1
- Where
- Sweden
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Lyme Disease, Lyme Neuroborreliosis
PEMF Therapy to Treat Lingering Symptoms of Lyme Disease After Treatment With Antibiotics
Overview PEMF Therapy for relief or reduction of lingering symptoms after antibiotic treatment of Lyme disease of participants in the UK.
- Conditions
- Lyme Disease, Lyme Neuroborreliosis, Lyme Arthritis, Unknown Origin Fever
- Trial name
- PEMF (NCT04577053)
- Testing
- Scientific Consciousness Interface Operations (SCIO) Class II FDA approved medical device
- Where
- 2 sites in United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kasey Phifer
Vaccine, Crimean-Congo Hemorrhagic Fever
Safety and Immunogenicity of a Self-Amplifying RNA Vaccine Against Crimean-Congo Hemorrhagic Fever
The goal of this clinical trial is to assess the safety, tolerability and immunogenicity of three dosage levels, and a single or two-dose administration regimen, of the investigational HDT-321 product administered…
- Trial name
- NCT06799013
- Testing
- 10 ug HDT 321, 25ug HDT-321, 50ug HDT-321
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- HDT Bio
Post-Acute COVID-19 Syndrome, ME/CFS
Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research
The unhide® Project is a non-interventional, longitudinal research study designed to establish a secure data repository of demographic, health, and lifestyle information from individuals with brain inflammation and related…
- Conditions
- Post-Acute COVID-19 Syndrome, ME/CFS, Rheumatic Arthritis, Juvenile Rheumatoid Arthritis (JRA)
- Trial name
- NCT04806620
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Brain Inflammation Collaborative
Crimean-Congo Hemorrhagic Fever
Phase I Study to Evaluate Basic Pharmacodynamic, Pharmacological and Toxicological Effects of the Newly Developed Crimean-Congo Hemorrhagic Fever Vaccine for Humans
This study covers the first trial of the Crimean-Congo Hemorrhagic fever virus (CKKA) vaccine on humans (healthy volunteers), which has been developed in Turkey and has completed preclinical toxicology studies to be performed on…
- Trial name
- NCT03020771
- Testing
- KIRIM-KONGO-VAX
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Scientific and Technological Research Council of Turkey
Scrub Typhus, Spotted Fever; India
The Epidemiology of Rickettsial Infections in South India: Cohort Study
There is enough evidence to suggest that scrub typhus and spotted fever group rickettsioses are common causes of febrile illness in India. Serological evidence also exists for murine typhus, but is rarely tested for.
- Conditions
- Scrub Typhus, Spotted Fever; India, Murine Typhus
- Trial name
- NCT04506944
- Testing
- No intervention
- Where
- India
- Volunteers
- 32,566 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine