Clinical trials: Tics
Major Depression, Mania
Reliability and Validity of the MINI International Neuropsychiatric Interview for Children and Adolescents (MINI-KID)
The primary aims of this study are to assess: 1. The inter-rater and test-retest reliability of the MINI-KID 2. The validity of the standard MINI-KID interview in relation to the parent rated pencil/paper version (MINI-KID-P) and…
- Conditions
- Major Depression, Mania, Anxiety Disorders, Psychotic Disorder
- Trial name
- NCT00579267
- Testing
- MINI-KID
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Tourette Syndrome
Impulsivity in Tourette Syndrome : Behavioral and Neuroimaging Study
Tourette syndrome (TS) is characterized by the presence of multiple vocal and motor tics. Behavioral disorders associated with TS are common, particularly impulsivity, anti-sociality and socially inappropriate behavior.
- Trial name
- COGIT (NCT02960698)
- Testing
- IRM and comportemental tasks
- Where
- France
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Tic Disorder, Tourette Syndrome
Role of the Sensory Experience in Generating Motor Tics in Tourette Syndrome
This study will investigate the sensation that many people with Tourette syndrome (TS) experience before they have a motor tic. It will also test whether blocking the sensation causes the tic to stop.
- Trial name
- NCT00755339
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Huntington's Disease, Tourette Syndrome
Brain Stimulation in Movement Disorders
Brain stimulation in movement disorders This trial will explore the effects of very gentle electrical stimulation of the brain in patients with movement disorders.
- Trial name
- NCT02216474
- Testing
- Transcranial direct current stimulation
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Birmingham and Solihull Mental Health NHS Foundation Trust
Tourette's Syndrome, Attention Deficit Hyperactivity Disorder
Study of Clonidine on Sleep Architecture in Children With Tourette's Syndrome (TS) and Comorbid ADHD
In the present study, we examine the question "Will day-time aggression in children improve when their night-time sleep is treated with pharmacological intervention (i.e.
- Trial name
- NCT00152750
- Testing
- APO-clonidine
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Tourette Disorder, Sensory Gating
Sensorimotor Integration in Patients With Tourette Syndrome
The present study investigates the mechanisms underlying the sense of agency in patients with Tourette Syndrome (TS). Previous research has shown that individuals with TS display impairments in both explicit and implicit aspects…
- Trial name
- ISM (NCT07290920)
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Healthy, Mental Disorder
I-123 Brain Studies of Serotonin Metabolism in Psychiatric Patients and Normal Volunteers
Abnormalities in the re-uptake of dopamine and serotonin have been described in various neuropsychiatric disorders and substance abuse.
- Conditions
- Healthy, Mental Disorder, Obsessive Compulsive Disorder, Schizophrenia
- Trial name
- NCT00001771
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Obsessive Compulsive Disorder, Healthy
Cortical Excitability in Obsessive-Compulsive and Related Disorders
This study will use transcranial magnetic stimulation (TMS) to study the function of the cerebral cortex (outer layer of the brain) in people with obsessive compulsive disorder (OCD) and related disorders.
- Trial name
- NCT00029068
- Where
- United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Bioequivalence
Bioequivalence Study of Feniramidol HCl 400 mg Film Tablet (Pharmactive, Turkey) Under Fed Conditions
OPEN-LABEL, RANDOMISED, SINGLE ORAL DOSE, FOUR-PERIOD, REPLICATED, CROSS-OVER TRIAL TO ASSESS THE BIOEQUIVALENCE OF FENIRAMIDOL HCl 400 MG FILM TABLET (TEST DRUG) IN COMPARISON WITH CABRAL 400 MG FILM TABLET (REFERENCE DRUG) IN…
- Trial name
- PHENYRAMIDOL (NCT04639869)
- Testing
- Phenyramydol HCl 400 mg Film Tablet, Cabral 400 mg Film Tablet
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Humanis Saglık Anonim Sirketi
Tourette Syndrome
Study of GABA-A Receptors in the Generation of Tics in Patients With Tourette's Syndrome
This study will investigate how the brain generates tics in patients with Tourette's syndrome and which areas of the brain are primarily affected.
- Trial name
- NCT00034398
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Tourette Syndrome
Behavioral Therapy for Children and Adolescents With Tourette Syndrome
Tourette Syndrome (TS) is a common neuropsychiatric disorder in childhood and adolescence, and often comorbid with psychiatric comorbidity.
- Trial name
- NCT03621059
- Testing
- habit reversal training (HRT)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Corneal Endothelium
Rates and Risk Factors of Contact Between the OTX-TIC Intracameral Ocular Implant and Corneal Endothelium
To determine what proportion of patients have inferior angle recess dimensions that could accommodate the OTX-TIC, and what are risk factors for implant contact with the corneal endothelium.
- Trial name
- NCT05835141
- Testing
- OCT Imaging
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Tourette Syndrome
Exploration of Glutamatergic System With PET Radiotracer in Gilles de la Tourette Patients: Pilot Study (GlutaTour)
Gilles de la Tourette syndrome is a neuropsychiatric disorder characterized by motor and vocal tics often associated with psychiatric comorbidities (obsessive compulsive disorder, anxiety and depressive syndrome, impulsivity).
- Trial name
- GlutaTour (NCT03681795)
- Testing
- Experimental MRI exam and PET scan exam with radiotracer
- Where
- France
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Obsessive-Compulsive Disorder
Characterization of Childhood-Onset Obsessive-Compulsive Disorder
The purpose of this study is to learn more about Obsessive-compulsive Disorder (OCD) in children. OCD usually has a slow onset, and symptoms that may remain at a stable level over time.
- Trial name
- NCT00044239
- Where
- 4 sites in United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Healthy
Bioequivalence Study of FLURBIPROFEN 100 mg FAMOTIDINE 20 mg MULTI-LAYER TABLET in Healthy Subjects Under Fasting Conditions
To assess the bioequivalence of Test oral formulation of FLURBIPROFEN 100 mg FAMOTIDINE 20 mg MULTI-LAYER TABLET versus Reference ANTADYS®100 mg Comprimé Pelliculé \& PEPCID® (Famotidine) 20mg Tablets, USP.
- Trial name
- NCT01910090
- Testing
- FLURBIPROFEN 100 mg FAMOTIDINE 20 mg MULTI-LAYER TABLET, ANTADYS® 100 mg, PEPCID® 20 mg
- Where
- Jordan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Pharmaceutical Research Unit, Jordan
Tourette Syndrome in Children, Tourette Syndrome in Adolescence
Extinction Learning in Youth With Tourette Syndrome
Aversive sensory phenomena such as premonitory urges play a central role in the behavioral treatment model of tics. Extinction learning and extinction recall are learning processes implicated within this model, but have not been…
- Conditions
- Tourette Syndrome in Children, Tourette Syndrome in Adolescence, Habit Reversal Training, Tic
- Trial name
- NCT03765463
- Testing
- Habit Reversal Training
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Tourette's Syndrome
Effects of Lactobacillus Plantarum PS128 in Patients With Tourette's Syndrome
To evaluate whether supplementing with PS128 can improve the symptoms and quality of life related to Tourette's disease in children.
- Trial name
- NCT04805385
- Testing
- PS128
- Where
- Taiwan
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Tourette Syndrome, Obsessive-Compulsive Disorder
Sensory Symptoms in Tourette Syndrome and Obsessive-Compulsive Disorder
This study seeks to address two key questions related to sensory dysregulation in Tourette syndrome (TS) and obsessive compulsive disorder (OCD): 1) Is sensory dysregulation in OCD clinically distinct from that in TS? 2) To what…
- Conditions
- Tourette Syndrome, Obsessive-Compulsive Disorder, Sensory Disorders
- Trial name
- SenST-Plus (NCT04335175)
- Testing
- None - observational study
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Labor Pain, Labor Onset
The Effects of Breathing Exercises and Virtual Reality Applications During Pregnancy and Labor.
Aim and Objectives: The purpose of this study was to determine the effects of breathing exercises and virtual reality applications during pregnancy and labor on labor pain, duration, and birth satisfaction.
- Conditions
- Labor Pain, Labor Onset, Patient Satisfaction, Virtual Reality
- Trial name
- NCT05527236
- Testing
- Breathing Exercise, Virtual Reality
- Where
- Turkey (Türkiye)
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Semra Çevik, phD
Chronic Pain, Chronic Pain Syndrome
Outcomes Mandate National Integration With Cannabis as Medicine
This will be a multistate, multicenter clinical study to determine the efficacy and safety of medical cannabis for a wide variety of chronic medical conditions.
- Conditions
- Chronic Pain, Chronic Pain Syndrome, Chronic Pain Due to Injury, Chronic Pain Due to Trauma
- Trial name
- OMNI-Can (NCT03944447)
- Testing
- Cannabis, Medical, RYAH-Medtech Inhaler
- Where
- 17 sites in United States
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- OMNI Medical Services, LLC