Clinical trials: Time
Comfort, Vision and Wear Time
Masked Comparison of a New PEG Based Artificial Tear and Optive for Comfort, Vision & Wear Time in Patients Wearing Contact Lenses
The objective of this study is to evaluate the effect of a new PEG based artificial tear as compared to Optive on comfort, wear time, and vision in patients wearing contact lenses.
- Trial name
- NCT00570843
- Testing
- New PEG based artificial tear, Optive
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Bp Consulting, Inc
Intrauterine Insemination
GnRH Agonist and Intrauterine Insemination
The aim of this study is to assess whether GnRH agonist administration in the luteal phase improves pregnancy outcome in intrauterine insemination (IUI) cycles.
- Trial name
- NCT00503217
- Testing
- Tryptorelin
- Where
- Spain
- Volunteers
- healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Crohn's Disease
A First Time in Human Study in Healthy Volunteers and Patients
A multi-part study to investigate the safety, tolerability and local and systemic pharmacokinetics of V565
- Trial name
- NCT03010787
- Testing
- V565
- Where
- United Kingdom
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- VHsquared Ltd.
Obesity Prevention
Food Advertisements, Satiety and Food Intake in Children
We hypothesized that FA in a TV program watched during a meal, would block satiety responses to pre-meal energy consumption and delay satiation in OW/OB but not in NW boys and girls.
- Trial name
- NCT01996514
- Testing
- Glucose with water, non-caloric sweetener with water, TV program with non-food advertisements while feeding
- Where
- Canada
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Feeding Behavior, Gastrointestinal Microbiome
The Timing of Main Meal Consumption Effect on Gut Microbiota and Host
The interplay between diet and the gut microbiota has been implicated in the onset of cardiovascular disease. The gut microbiota displays diurnal rhythms, which may be influenced by meal timing.
- Conditions
- Feeding Behavior, Gastrointestinal Microbiome, Diet, Meal Time
- Trial name
- TIMC (NCT03949543)
- Testing
- Large Lunch Intervention, Large Dinner Intervention
- Where
- United Kingdom
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
OVARIAN STIMULATION
Follicular Volume at the Time of Final Oocyte Maturation in Poor Responders, and Its Correlation With Oocyte Maturity
Women with a severely diminished ovarian reserve and monofollicular growth are at a higher risk of premature ovulation as well as poor quality oocytes.
- Trial name
- NCT06839274
- Testing
- transvaginal Ultrasound
- Where
- United Arab Emirates
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Smiling, Botulinum Toxins, Type A
Higher Doses of Botulinum Toxin in the Treatment of Gummy Smile
Botulinum type A (BTX-A) is an easy and efficacious treatment for gingival smile (GS). However, the necessary for higher-doses among patients are controversial.
- Trial name
- NCT05127018
- Testing
- injection of Botulinum type A
- Where
- China
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Peking University
Meconium, Breastfeeding
Breastfeeding Success and Time of First Meconium Passage
To investigate the relationship between breastfeeding success and the time of first meconium passage in term newborns.
- Trial name
- NCT06950658
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Halitosis, Periodontitis
Oral Malodour and Periodontal Disease-related Parameters
The primary aim of the current study was to determine the association between halitosis detection (presence or absence) and periodontal status in non-smoking subjects, and also assess whether halitosis recordings were related to…
- Conditions
- Halitosis, Periodontitis, Gingivitis
- Trial name
- NCT01234948
- Where
- Greece
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Operative Time, Wound Heal
Subcuticular Absorbable Staples Versus Conventional Skin Closure in Women Undergoing Cesarean Delivery
Despite the high numbers of cesareans being performed, scientific evidence behind which surgical techniques are best remains uncertain.
- Trial name
- NCT05112640
- Testing
- INSORB: subcuticular stapling device, Subcuticular monocryl suture manufactured by Ethicon
- Where
- United States
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Non-Alcoholic Fatty Liver Disease, Time Restricted Feeding
Effects of Time-restricted Eating Supported by Mobile Technology in Patients With Non-alcoholic Fatty Liver Disease: Randomized Controlled Trial
In non-alcoholic fatty liver disease (NAFLD), it is established that calorie restriction is the most essential dietary modification.
- Conditions
- Non-Alcoholic Fatty Liver Disease, Time Restricted Feeding, Mobile Technology
- Trial name
- NCT05579158
- Testing
- Mobile application and wearable device, Time-restricted eating
- Where
- South Korea
- Volunteers
- 337 people, healthy volunteers welcome
- Sponsor
- Hanyang University
Sedentary Lifestyle
The Effects of Smartphone Use on Physical Activity, Sedentary Behaviour, Sleep, and Well-being
Previous studies suggest that screen use (phones, TV, computers, etc) may negatively impact both sleep and mental health (1-3). The purpose of this study is to determine the impact of reducing smartphone use on sleep, physical…
- Trial name
- NCT03752385
- Testing
- reducing smartphone screen time
- Where
- Canada
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Prince Edward Island
Bladder Function
Pilot Trial in Sleep Laboratory Setting to Compare the Physiology of Night Time Bladder Function in Subjects With Overactive Bladder (OAB) Versus Subjects That Have Insomnia and Healthy Normal Subjects
This is an observational, physiology pilot study of subjects with overactive bladder, insomnia and normal subjects. No study drug will be given. All subjects will complete a one week sleep diary and a 3-day bladder diary.
- Trial name
- Nocturia Plt 1 (NCT01029015)
- Testing
- cystometry, polysomnography
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Inc
Smoking Cessation, Smoking, Cigarette
Pictorial Warning Labels and Memory for Cigarette Health-risk Information Over Time
Pictorial cigarette warning labels (PWLs) are thought to increase risk knowledge, but experimental research has not examined PWLs' longer term effects on memory for health risks.
- Trial name
- NCT03375840
- Testing
- Text-only PWL, Low-emot PWL, High-emot PWL
- Volunteers
- 4,424 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Depressive Disorder and Anxiety Disorders
A First Time in Human Study of GSK586529 in Healthy Volunteers
A single blind, randomized, placebo-controlled, crossover study in twenty four healthy male subjects. Subjects will be divided into two cohorts with alternate panel design.
- Trial name
- NCT00703547
- Testing
- GSK586529 capsules, GSK586529 tablets
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
COPD
Detection of Early Airway Obstruction in Patients With COPD Using RCexp
We hypothesize that Cexp during tidal and forced exhalation implemented to the routine spirometer may detect airway obstruction earlier than conventional spirometric indices such as FEV1 and FEV1/FVC.
- Trial name
- COPD TiCON (NCT06456047)
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- East Slovak Institute for Cardiovascular Diseases
Problematic Video Gaming
Effects of Temporary Abstinence and Expressive Writing on Gaming
The goal of this clinical trial is to investigate if an intervention combining temporary abstinence and expressive writing can mitigate gaming problems in young adult regular gamers.
- Trial name
- NCT07068035
- Testing
- Temporary abstinence and expressive writing, Gaming as per usual and control writing
- Where
- Singapore
- Volunteers
- 321 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Repetitive Negative Thinking, Neurofeedback
Effect of Mindfulness-based Neurofeedback for Adolescents With Elevated Repetitive Negative Thinking
This study will test the hypotheses that adolescent with repetitive negative thinking who at at-risk for serious mental illness will show greater default mode network (DMN) connectivity than healthy controls, at-risk adolescents…
- Trial name
- CHARMS (NCT07055217)
- Testing
- Mindfulness Training, Mindfulness-based Neurofeedback (Real mbNF)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Respiratory Tract Infection, Infections, Bacterial
A Three-Part Study Of GSK580416 In Healthy Subjects
Studies for GSK580416 have been completed in rats and dogs. The main toxic effects seen in animals affected the digestive system and blood cells. Study OPS106400 will be the first administration of GSK580416 in humans.
- Trial name
- NCT00427141
- Testing
- GSK580416
- Where
- Australia
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Pilonidal Disease, Pilonidal Sinus
Effect of Platelet Rich Plasma (PRP) on Healing Time in Patients Following Pilonidal Sinus Surgery
Our study was planned as a prospective controlled randomized study. The study was started after the ethics committee approval received from Dışkapı Yıldırım Beyazıt Training and Research Hospital. (23.08.2021 118/01).
- Trial name
- NCT06206330
- Testing
- Platelet rich plasma
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- İsmail Oskay Kaya