Clinical trials: Time Management
Propofol Adverse Reaction, Anesthesia
Impact of Propofol Reduction in Anesthesia Induction
Objective: Determine if, by reducing the dose of propofol and increasing the time elapsed between fentanyl and propofol administration, hemodynamic response is improved.
- Trial name
- NCT04194151
- Testing
- Propofol Injection
- Where
- Spain
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Hospital Central de la Defensa Gómez Ulla
Healthy Subjects
A Study in Healthy Male Subjects to Investigate Whether Administration of ACT-541468 Can Affect the Fate in the Body (Amount and Time of Presence in the Blood) of Rosuvastatin
A study in healthy male subjects to investigate whether administration of ACT-541468 can affect the fate in the body (amount and time of presence in the blood) of rosuvastatin
- Trial name
- NCT03339752
- Testing
- Rosuvastatin, ACT-541468
- Where
- Czechia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Idorsia Pharmaceuticals Ltd.
Weight, Body
Time Restricted Eating With or Without a Fiber Supplement for Weight Management in Pediatric Cancer Survivors
This study aims to address a critical gap in pediatric oncology survivorship care by exploring innovative solutions to addressing obesity and its comorbidities in pediatric cancer survivors.
- Trial name
- NCT05826184
- Testing
- Time restircted eating, Time restricted eating + prebiotic
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Healthy
Single Increasing Dose Followed by Maintenance Dose Tolerance Study of BIIR 561 CL in Healthy Male Volunteers
The objective of the present study is to obtain information about the safety, tolerability and pharmacokinetics of BIIR 561 after continuous intravenous administration of increasing doses in healthy young volunteers
- Trial name
- NCT02222961
- Testing
- BIIR 561 CL
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
Single Increasing Doses of BIII 890 CL in Healthy Young Male Volunteers and in Healthy Elderly Male and Female Volunteers
Safety, tolerability and pharmacokinetics of BIII 890
- Trial name
- NCT02269215
- Testing
- BIII 890 CL
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Labor Pain
The Effect of Continuous Midwifery-led Care in Birth Management
Caesarean section is an emergency procedure necessary to prevent harm or death to the mother or newborn. Worldwide, caesarean section rates are steadily increasing.
- Trial name
- NCT06660615
- Testing
- MIDWIFE-LED CARE
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Medication Administered in Error, Medication Adverse Effects
Identifying Drug-related Problems at ED Triage (DRP-EDiT) V1
Up to a third of patients who visit emergency departments (EDs) do so because they have an issue with medicines prescribed by their doctor or purchased over the counter.
- Conditions
- Medication Administered in Error, Medication Adverse Effects, Medication Reaction
- Trial name
- DRP-EDiT (NCT05476705)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Anglia Ruskin University
Cesarean Section, Infection
Trial Comparing the Optimal Timing of Antibiotic Prophylaxis at the Time of Cesarean Delivery
The purpose of this study is to evaluate the rates of maternal and neonatal infectious morbidity in gravid patients undergoing cesarean delivery.
- Trial name
- NCT00811603
- Testing
- Cefazolin (Timing of Antibiotic Prophylaxis)
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- MemorialCare
Obesity
The Effect of 5-Hydroxytryptophan (5-HTP) on Satiety
The aim of the study is to show evidence of the efficacy of 5-HTP to induce satiety and to reduce food intake (confirmatory study).
- Trial name
- NCT00328913
- Testing
- 5-hydroxytryptophan (food supplement)
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- TNO
Meconium Obstruction of Prematurity
Saline Enema Administration in Meconium Obstruction of Prematurity and Impact on the Resolution, Feeds, Microbiome, and Gut-brain Axis.
The goal of this clinical trial is to study the effect of twice-daily saline enema (SE) in the treatment obstruction of prematurity (MOP) in infants with the birth weight ≤1.25kg.
- Trial name
- NCT06048614
- Testing
- Saline Enema (SE), Glycerin Suppository
- Where
- 2 sites in Singapore
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Tuberculosis
Safety, Tolerability And Pharmacokinetics Study Of Single Doses Of PNU-100480 In Healthy Adults
The purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics of PNU-100480 (PF-02341272) after a single dose in healthy adult volunteers.
- Trial name
- NCT00871949
- Testing
- PNU-100480
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Sequella, Inc.
Newborn; Vitality, Nursing Caries
Effect of Intranasal Breast Milk Administration in Preterm Infants
The aim of the study was to investigate the effect of intranasal breast milk administration on cerebral oxygenation level, vital signs and time to full oral feeding in preterm infants.
- Conditions
- Newborn; Vitality, Nursing Caries, Breast Feeding
- Trial name
- NCT06706115
- Testing
- Intranasal human breast milk
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Selcuk University
To Compare the Time Required to Administer 1 mg of Epinephrine, as Well as the Total Procedure
Vascular Access and Intraosseus
Rapid administration of epinephrine is an essential component of advanced life support during cardiac arrest. Peripheral intravenous (IV) access is commonly used for drug delivery, while intraosseous (IO) access is an alternative…
- Trial name
- IO_nursing (NCT07471555)
- Testing
- Epinephrine Ampoule (Manual Preparation), Epinephrine Prefilled Syringe (Ready-to-use), Intravenous (IV) Access
- Where
- Spain
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Oral Surgical Procedure
Efficacy of Dexamethasone or Adrenaline in Inferior Alveolar Nerve Block
Oral and dental professionals were responsible for the discovery of anaesthesia, given their close day-to-day contact with pain and, hence, their motivation to seek the means to alleviate it.
- Trial name
- NCT04850885
- Testing
- inj dexamethasone 4mg/ml and inj lignocaine 20mg/ml
- Where
- Nepal
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Tribhuvan University, Nepal
Smartphone Addiction, Breastfeeding
SMaRT Mom - Smartphone Management and Responsive Time for Breastfeeding Mothers
In the last decade, infants are born into a social environment in which the smartphone has become an essential part of our lives.
- Conditions
- Smartphone Addiction, Breastfeeding, Infant Behavior, Mother-Infant Interaction
- Trial name
- SMaRT (NCT06030830)
- Testing
- SMaRT Mom
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Bar-Ilan University, Israel
Gonococcal (GC) Infection
A Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD0914
The purpose of this study is to assess the safety and tolerability of orally administered AZD0914 in healthy adult subjects.
- Trial name
- NCT01929629
- Testing
- Part A, Part B
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Healthy
A Study in Healthy Subjects to Investigate Whether Administration of Lucerastat Can Affect Normal Heart Function
Two-part Phase 1 study to assess the effect of single therapeutic and supra-therapeutic doses of lucerastat on the QT/QTc interval duration in healthy subjects (Part A: Pilot study; Part B: TQT study)
- Trial name
- NCT03832452
- Testing
- Lucerastat (Treatment A), Moxifloxacin, Lucerastat (Treatment B)
- Where
- Netherlands
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Idorsia Pharmaceuticals Ltd.
Liver Diseases
Fibrinogen Concentrates Versus Cryoprecipitate in Liver Transplant Surgery
We compared the time consumed for goal-directed management of hypofibrinogemia using two strategies during liver transplant (LT) surgery: a conventional cryoprecipitate-based strategy versus a lyophilized fibrinogen…
- Trial name
- NCT06144112
- Testing
- fresh frozen plasma, prothrombin complex concentrate
- Where
- South Korea
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Konkuk University Medical Center
Tendinopathy, Jumper's Knee
A Study of the Effect of Time-of-day of Training on Chronic Patellar Tendinopathy
The study is a 12-week human study where 60 participants with chronic patellar tendinopathy (more than 3 months symptoms duration) are randomised to undergo 12 weeks of targeted resistance exercise either in the morning or in the…
- Trial name
- TENDOTIME (NCT06217432)
- Testing
- Resistance training for knee extensors
- Where
- Denmark
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Drug Interactions
Study to Learn More About the Effect of Itraconazole (ITZ) Given Repeatedly by Mouth on the Way How the Study Drug BAY1902607 Given One Time by Mouth Acts in the Human Body of Healthy Male Participants
BAY1902607 is a new type of drug under clinical development for different conditions including the treatment of endometriosis, i.e. a condition where the tissue that usually grows inside the womb grows outside of the womb.
- Trial name
- NCT03789890
- Testing
- BAY1902607, Itraconazole
- Where
- Germany
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Bayer