Clinical trials: Time Management
Amputation
Dynamic Management of Excess Residual Limb Pressure With New Smart Socket Technology/Intelligent Prosthetic Socket With Variable Volume and Elevated Vacuum Systems
This study centers around the imaging of internal structures of residual limb by means of modern radiographic imaging techniques (Dynamic Radiography-DRSA).
- Trial name
- SMARTsocket- (NCT01108536)
- Testing
- adaptive prosthetic socket
- Where
- 3 sites in United States, Cyprus
- Volunteers
- 60 people
- Sponsor
- University of Wisconsin, Milwaukee
Cerebrovascular Accident
Anti-MAG First Administration to Human
GSK249320 is a monoclonal antibody directed against myelin associated glycoprotein (MAG), a protein that inhibits axonal regeneration.
- Trial name
- NCT00622609
- Testing
- GSK249320A
- Where
- 2 sites in United States, Australia
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Pulmonary Aspiration During Anaesthetic Induction, Gastric Emptying Time
Gastric Emptying With Metoclopramide in GLP-1 Agonist Patients Undergoing Elective Surgery
This is a multicentre, investigator-blinded, randomised controlled trial evaluating whether the use of oral metoclopramide before surgery can reduce the amount of residual gastric content in patients who are taking glucagon-like…
- Conditions
- Pulmonary Aspiration During Anaesthetic Induction, Gastric Emptying Time, Preoperative Risk Assessment, Obesity (Disorder)
- Trial name
- GEM-GLP1RA (NCT07100691)
- Testing
- Metoclopramide
- Where
- 2 sites in Ireland
- Volunteers
- 80 people
- Sponsor
- Mater Misericordiae University Hospital
Osteo Arthritis Knee and Hip
Predicting The Right Advice at The Right Time in Patients With Hip and Knee OsteoArthritis: the e-cOAch Cross-over.
This study aims to learn how symptoms and daily functioning change over time in people with hip or knee osteoarthritis (OA). The goal is to use this information to build computer models that can predict these changes.
- Trial name
- e-cOAch (NCT07423858)
- Testing
- Physical Activity program, Sleep program, Weight management program
- Where
- Netherlands
- Volunteers
- 600 people
- Sponsor
- UMC Utrecht
Healthy
Single Increasing Dose Tolerance Study in Healthy Male Volunteers of BIIR 561 CL
The objective of the study is to obtain information about safety, tolerability and pharmacokinetics of BIIR 561 CL after single intravenous administration of increasing doses in healthy male volunteers
- Trial name
- NCT02222974
- Testing
- BIIR 561 CL
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Schizophrenia
A Study Of The Safety, Tolerability And Pharmacokinetics Of Single Doses Of PF-05180999 In Healthy Adults
The purpose of this study is to determine the safety, tolerability, and pharmacokinetics of 14 days of treatment with PF-05180999 in healthy subjects.
- Trial name
- NCT01429740
- Testing
- PF-05180999
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Pfizer
Modified Radical Mastectomy
Comparison of Mean Duration of Analgesia Following the Administration of Bupivacaine With and Without Magnesium Sulphate in Ultrasound Guided Erector Spinae Plane Block in Modified Radical Mastectomy Patients
To compare mean duration of postoperative analgesia following the administration of bupivacaine with and without magnesium sulphate in erector spinae plane block in modified radical mastectomy patients.
- Trial name
- NCT07460115
- Testing
- Group B (bupivacaine), Bupivacaine plus magnesium sulfate
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gulab Devi Hospital
Ebola Virus Disease, Marburg Virus Disease
Evaluation of Safety, Tolerability and Immune Responses of Ebola-S and Marburg Vaccines in Healthy Adults
Primary Objective: To evaluate the safety and tolerability of cAd3-EBO-S and cAd3 Marburg vaccines when administered Intramuscular (IM) at a dose of 1 x 10^11 particle units (PU) to healthy adults.
- Trial name
- NCT04723602
- Testing
- cAd3-Marburg, cAd3-EBO-S
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Albert B. Sabin Vaccine Institute
Congenital Heart Disease
Extubation Times in Postoperative Congenital Cardiovascular Surgeries
Background: Anesthesia management in pediatric cardiac surgeries focuses on reducing morbidity and mortality, early mobilization and discharge, using health resources sparingly and increasing the quality of life of patients.
- Trial name
- NCT05332860
- Testing
- Congenital Cardiovascular Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Autologous Transplantation
Alteration in Timing of Plerixafor Administration
Typically, the collection of blood cells for autologous stem cell transplant is done after the drugs granulocyte colony-stimulating factor (G-CSF) and plerixafor have been given to activate the bone marrow stem cells to produce a…
- Trial name
- NCT01149863
- Testing
- Plerixafor
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Emory University
Influenza, Vaccination Site Reactions (HT)
A Time-motion Study Comparing Self- to Nurse-vaccination With Influenza Vaccine
The investigators hypothesize that people working in an acute care hospital setting will be able to successfully self-administer the intradermal vaccine (Intanza) in less time than nurse-administration of the regular…
- Trial name
- NCT01665807
- Testing
- Intanza, Vaxigrip
- Where
- 2 sites in Canada
- Volunteers
- 868 people, healthy volunteers welcome
- Sponsor
- Brenda Coleman
Optimal Vitamin D Administration
Oral Vitamin D Supplementation in Elderly Women
The aim of this study is to compare oral vitamin D supplementation administered in two different ways, namely either twice a day (800IU/d, 292000IU/y) or three times a year (97333IU every 4 months, 292000IU/y) in elderly women in…
- Trial name
- NCT00575835
- Testing
- vitamin D twice daily, Vitamin D3 oil three times in a year
- Where
- Finland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Type 1 Diabetes
Absorption of Insulin Following Subcutaneous Bolus Administration With Different Bolus Durations
To cover meal-related insulin requirements, insulin pumps allow insulin to be delivered at high rates over a short period of time (bolus delivery).
- Trial name
- NCT01792323
- Testing
- Insulin LISPRO
- Where
- Austria
- Volunteers
- 20 people
- Sponsor
- Medical University of Graz
Labor Pain
Study of the Effectiveness of Administration of Meperidine on the Length of Active Phase of Labor in Women
This study aims to evaluate the effect of meperidine on the length of active phase of labor in nulliparous or multiparous women, who will be randomized into two (control and study) groups.
- Trial name
- NCT01555671
- Testing
- Meperidine, Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Pregnancy
Study to Determine if Monitoring of Labor Shortens the Time to Delivery
The purpose of this study is to test the hypothesis that using the BirthTrack for management of labor shortens the time to delivery and thus improves both maternal and perinatal outcomes.
- Trial name
- BirthTrack (NCT01005667)
- Testing
- BirthTrack
- Where
- Canada
- Volunteers
- 600 people
- Sponsor
- Barnev, Inc.
Subfertility
Is the IVF Outcome Dependent on the Time Interval Between hCG Administration and Oocyte Retrieval?
During controlled ovarian hyperstimulation (COH), human chorionic gonadotrophin (hCG) is administered to trigger the final follicular maturation before oocyte retrieval, in an attempt to mimic the physiologic effects of LH.
- Trial name
- NCT02044445
- Testing
- Oocyte retrieval will be performed 36 h or 38 h after hCG administration
- Where
- Greece
- Volunteers
- 154 people
- Sponsor
- Aristotle University Of Thessaloniki
Midazolam
Pharmacokinetic Evaluation of MDZ028
Plasma concentration data were collected from 37 paedriatic patients and 12 healthy adults recruited in a single dose, open-label phase II pharmacokinetic study and in a single dose, randomised, open-label two-peiod crossover…
- Trial name
- MIDAZOLAM (NCT03639428)
- Testing
- Midazolam
- Volunteers
- 37 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Stroke
Study of the Performance of Stroke Management in the Rhône Area
Acute stroke management represents a true medical emergency that requires prompt diagnosis and urgent treatment. However, only a small percentage of patients access to thrombolysis on time.
- Trial name
- STROKE 69 (NCT02596607)
- Where
- 7 sites in France
- Volunteers
- 3,454 people
- Sponsor
- Hospices Civils de Lyon
Chronic Pain, Multidisciplinary Biopsychosocial Program
Real-time Treatment of Chronic Pain Using Digital Intelligence
This randomized controlled study will evaluate the effectiveness of real-time digital intelligence in the treatment of chronic pain.
- Conditions
- Chronic Pain, Multidisciplinary Biopsychosocial Program, Quality of Life
- Trial name
- NCT07454811
- Testing
- tandard Treatment + Digital Monitoring (Intervention Group), Standard Multidisciplinary Treatment (Control Group)
- Where
- Croatia
- Volunteers
- 80 people
- Sponsor
- Osijek University Hospital
Management and Epidemiology of Patients Admitted in ICU
Hospitalizations During Pandemia in the Italian Coronary Care Unit Network
Multicentre, national, observational, retrospective and prospective study. The BLITZ-COVID19 study aims at describing the epidemiology of admissions to Italian Cardiology Intensive Care Units in the COVID-19 infection pandemia…
- Trial name
- BLITZ-COVID19 (NCT04744415)
- Testing
- Epidemiology of admissions
- Where
- 109 sites in Italy
- Volunteers
- 6,054 people
- Sponsor
- Heart Care Foundation