Clinical trials: Time Management
Mandibular Fracture Treatment
Inter Flex Three Dimensional Plate in Management of Mandibular Fracture RCT
The goal of this clinical trial is to learn if The use of a 3D-designed Inter-flex plate will achieve safe and desirable anatomical \& functional restoration with reduced operative time in mandibular fracture, Improvement of…
- Trial name
- NCT07263893
- Testing
- Group I :site with mandibular fracture will be treated with custom made Inter-flex three dimensional plate in site of mandibular fracture
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Suez Canal University
Heart Failure, Diabetes Mellitus
CGM Use in Heart Failure
Heart failure (HF) is a major cause of hospital admissions in the US, with over 6 million hospital days annually. More than 40% of hospitalized patients with HF have diabetes mellitus (DM), which increases the risk of recurrent…
- Trial name
- NCT07045298
- Testing
- Libre 2 rt-CGM, POC BG + Blinded CGM
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Emory University
Bipolar Disorder (BD), Major Depressive Diorder
Stress Management With Real-time Bio-signal Biofeedback
The goal of this clinical trial is to learn if the real-time bio-signal monitoring device (Neuronicle FX2 device), combined with mindfulness-based cognitive therapy (MBCT), helps manage stress and improves symptoms of mood…
- Trial name
- NCT06616116
- Testing
- Biosignal feedback
- Where
- South Korea
- Volunteers
- 140 people
- Sponsor
- Seoul National University Hospital
Pain, Postoperative
An Efficacy and Safety Study to Compare Fentanyl Ionsys and Routine Care With Intravenous (IV) Morphine Patient-controlled Analgesia (PCA) in Participants Who Have Undergone Elective Major Abdominal or Orthopedic Surgery
The purpose of this study is to evaluate the mobilization characteristics, clinical use, safety and Ease of Care (EOC) of a fentanyl Iontophoretic Transdermal Patient Controlled Analgesia (PCA) system (Ionsys) and morphine…
- Trial name
- NCT00766506
- Testing
- Fentanyl IONSYS, Morphine IV PCA
- Where
- 7 sites in United Kingdom
- Volunteers
- 108 people
- Sponsor
- Janssen-Cilag Ltd.
Chronic Urticaria
Levocetirizine Plus Bed-Time Hydroxyzine in the Management of Corticodependent Chronic Urticaria Versus Levocetirizine Alone in High Doses
Allen Kaplan is a prominent American allergist with the reputation of leader in the field of chronic urticaria. He advocates treatment with first generation hydroxyzine, which he considers at least as effective as modern second…
- Trial name
- LevoHydroxy (NCT01250652)
- Testing
- Levocetirizine, Levocetirizine plus Hydroxyzine
- Where
- Bulgaria
- Volunteers
- 24 people
- Sponsor
- Association Asthma, Bulgaria
Influenza, COVID-19
Comparative Immunogenicity of Concomitant vs Sequential mRNA COVID-19 and Influenza Vaccinations
This is a prospective, randomized randomized immunologic study of response to influenza and SARS-CoV-2 vaccination across four of the US Influenza Vaccine Effectiveness (Flu VE) Network study sites.
- Trial name
- NCT06020118
- Testing
- Simultaneous Vaccination (Influenza Vaccine and mRNA COVID booster), Sequential Vaccination (Influenza vaccine then mRNA COVID booster), Sequential Vaccination (mRNA COVID booster then Influenza vaccine)
- Where
- 8 sites in United States
- Volunteers
- 455 people, healthy volunteers welcome
- Sponsor
- Duke University
Duration of Estrogen Administration
The Impact of Estrogen Administration Duration in Hormonally Prepared Frozen Embryo Transfer Cycles
This prospective controlled study aimed to investigate the effect of the duration of estrogen (E2) administration prior to progesterone (P) initiation on live birth rates (LBR) in frozen embryo transfer (FET) cycles.
- Trial name
- NCT05825885
- Testing
- E2
- Where
- Turkey (Türkiye)
- Volunteers
- 420 people
- Sponsor
- Akdeniz University
Shoulder Pain, Injury of Shoulder Region
Plasma Glucose Levels With Dexamethasone as Adjuvant to Interscalene Block
The purpose of this study is to determine the Finger Blood Glucose (sugar) when dexamethasone is added to a local anesthetic for a shoulder nerve block procedure.
- Conditions
- Shoulder Pain, Injury of Shoulder Region, Disorder of Shoulder, Disorder of Rotator Cuff
- Trial name
- NCT01538459
- Testing
- Dexamethasone, Bupivacaine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Lifespan
Pre-obesity, Obesity
DIGITALIZATION OF PERSONALISED HEALTH RISK MANAGEMENT
The principal objective of the project is: to bring together academic and business research organisations in a joint partnership integrating technological and social innovation, in order to develop proof-of-concept of a scalable…
- Trial name
- DIG4HEALTH (NCT06983431)
- Testing
- technology driven self coaching, Health coaching, Peer coaching
- Where
- Slovakia
- Volunteers
- 320 people
- Sponsor
- Slovak Academy of Sciences
Healthy Participants, Obesity
A Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD1043 in Healthy Adult Participants Living With Overweight and/or Obesity.
The purpose of the study is to assess the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of AZD1043 following single and multiple ascending doses in healthy adult participants living with overweight and/or…
- Trial name
- NCT07511205
- Testing
- AZD1043
- Where
- 3 sites in United States, United Kingdom
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Lung Cancer, Medication Adherence
Implementation Strategies for Monitoring Adherence in Real Time
The objective of this project is to identify effective strategies to help patients with lung cancer manage side effects and achieve optimal adherence to oral targeted therapies.
- Conditions
- Lung Cancer, Medication Adherence, Symptoms and Signs
- Trial name
- iSMART (NCT04347161)
- Testing
- Conversational Agent/Chatbot, Usual Care
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Diabetes
Role of Interrupting Sedentary Time in Management of Type-2 Diabetes
Type-2 diabetes, a common non-infectious disease, is the result of impaired insulin function and insulin production in the body.
- Trial name
- Just_StandUp (NCT02738996)
- Testing
- Sedentary time breaks either every 60 minutes, Sedentary time breaks either every 30 minutes, Sedentary time breaks every 15 minutes
- Volunteers
- 24 people
- Sponsor
- Glasgow Caledonian University
Appendicitis, Child
CT Scan Using IV Contrast Alone for Pediatric Appendicitis
Computed tomography (CT) scan using intravenous contrast (CT IV) as the sole type of contrast material, was studied as one method of evaluating children with suspected appendicitis.
- Conditions
- Appendicitis, Child, Contrast Media
- Trial name
- NCT00716703
- Testing
- CT Scan using IV contrast alone
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Rochester
Induction of Labor
Using Isosorbide Mononitrate in Reducing Time in Induction of Labor in Post Date Women
We will compare between using isosorbide mononitrate together with misoprostol versus the misoprostol alone in induction of labor in postdate women
- Trial name
- NCT03854383
- Testing
- Isosorbide mononitrate, Misoprostol
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Abdelrahman Ali Fadel Youssef Mohamed
Shock, Septic
Effect of Albumin Administration on Vasopressor Duration in Resolving Septic Shock
The role of albumin in sepsis has been controversial for decades. Although hypoalbuminemia has been associated with worse outcomes in sepsis, definitive evidence does not exist that replacing albumin in these patients improves…
- Trial name
- NCT02716597
- Testing
- 25% Albumin
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Alexander Flannery, 859-323-4011
Medication Administered in Error, Medication Compliance
The IMPROVE Study-IMPact of a Regulated ADC System
An automated dispensing cabinet (ADC) is a computerized drug storage device or cabinet designed for hospitals. ADCs allow medications to be stored and dispensed near the point of care while controlling and tracking drug…
- Trial name
- IMPROVE (NCT02228694)
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hackensack Meridian Health
Needlestick Injuries
The Influence of Injection Speed on Pain During Administration of Local Anaesthetic.
This study will investigate the influence of injection speed on pain during injection of lidocaine. It is anticipated that a longer injection time will lead to less pain for the patient during the injection.
- Trial name
- NCT02107742
- Testing
- Normal speed lidocaine injection, Slow lidocaine injection, Fast lidocaine injection
- Where
- Norway
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Intubation; Difficult or Failed, Intubation Complication
Non-inferiority Trial Comparing visionPRO to Glidescope Video Laryngoscopes
Indirect video laryngoscope tracheal intubation with the GlideScope (Verathon Inc., Bothell, USA) has become a well-established technique in emergency and clinical anaesthesia, offering first-pass intubation success rates…
- Conditions
- Intubation; Difficult or Failed, Intubation Complication, Video Laryngoscopy, Airway Management
- Trial name
- NCT06676462
- Testing
- Video laryngoscopy with visionPRO, Video laryngoscopy with Glidescope
- Volunteers
- 100 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Nurse
Effectiveness of Teaching Program for the Management of Upper GI Bleeding
A study to assess the effectiveness of teaching program for the management of upper GI bleeding in terms of gain in nurses' practice and knowledge related to management of upper GI bleeding among chronic liver disease patients…
- Trial name
- NCT05207410
- Where
- India
- Volunteers
- 20 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Stroke, Ischemic
Intra-Arterial Neuroprotective Agents and Cold Saline in Ischemic Stroke Intervention
Ischemic stroke is the leading cause of long-term disability in the United States. Endovascular intervention with mechanical thrombectomy has become the standard of care for acute large vessel occlusion (LVO) stroke since…
- Trial name
- NCT05032781
- Testing
- Intra-arterial cold saline, minocycline, and magnesium
- Where
- United States
- Sponsor
- Northwell Health