Clinical trials: Tinnitus
Tinnitus
Genetically-informed Behavioral and Cognitive Interventions for the Management of Tinnitus
Psychological and behavioral interventions, such as Cognitive Behavioral Treatment (CBT) and Tinnitus Retraining Therapy (TRT), are commonly applied either alone or in combination for the management of tinnitus but selection of…
- Trial name
- NCT04675112
- Testing
- Cognitive Behavioral Treatment (CBT) and Tinnitus Retraining Therapy (TRT)
- Where
- Greece
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Gkouskou Kalliopi
Tinnitus
Investigating EEG as a Biomarker for Tinnitus Improvement After Bimodal Stimulation
The aim of the proposed study is to investigate the use of resting-state Electroencephalogram (EEG)-Based Brain Entropy (EBDBE) and auditory brainstem responses (ABR) as an objective measure of tinnitus improvement following the…
- Trial name
- NCT07158034
- Testing
- Lenire Device
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Sensorineural Hearing Loss, Tinnitus
ACEMg Hearing Preservation, Tinnitus and Hyperacusis Relief
ACEMg (Soundbites) is a neuroprotectant supplement designed to block the initiating biological events in the inner ear leading to inner ear hearing loss, sensorineural hearing loss, SNHL, which accounts for more than 90% of all…
- Conditions
- Sensorineural Hearing Loss, Tinnitus, SNHL, Inner Ear Hearing Loss
- Trial name
- OTISRWD (NCT06477354)
- Testing
- ACEMg
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Keep Hearing, Inc.
Tinnitus, Subjective
Mechanism Research of Tinnitus Based on Electroencephalogram and Acoustic Therapy Intervention
This project aims to systematically and deeply study the central mechanism of tinnitus using electroencephalogram, and further study the treatment mechanism of tinnitus in combination with sound treatment strategies, so as to…
- Trial name
- EEG-RCT (NCT04449237)
- Testing
- music therapy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Eye & ENT Hospital of Fudan University
Tinnitus
Neuro-Music Therapy for Recent Onset Tinnitus: Evaluation of a Therapy Concept
To date, the pharmacological treatment options for tinnitus are unsatisfactory. For acute tinnitus drug treatments are only rated as being successful in approximately half of all cases.
- Trial name
- NCT01566708
- Testing
- Neuro-Music Therapy immediately, Neuro-Music Therapy after waiting time, Music-therapeutical stress management coaching
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- German Center for Music Therapy Research
Listening Effort, Tinnitus
Listening Effort in Tinnitus Patients
About 5-15% of the general population experience a chronic ringing, buzzing, hissing or roaring sound in one or two ears, without any external source.
- Trial name
- ALERT (NCT05884879)
- Testing
- Tinnitus simulation
- Where
- Netherlands
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Hearing Loss, Hearing Disorders
Validation of a Smartphone-Based Hearing-in-Noise Test (HearMe)
The purpose of this project is to validate a quick, easy-to-use and administer smartphone hearing-in-noise test. The Hearing-in-Noise Test (HINT) measures an individual's ability to hear speech in quiet and in noise.
- Conditions
- Hearing Loss, Hearing Disorders, Hearing Abnormality, Hearing Disability
- Trial name
- HearMe (NCT03429777)
- Testing
- HearMe Smartphone Application
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Iowa
Tinnitus
Using PET-CT to Target and Validate Low-frequency TMS as Treatment for Tinnitus
One out of every five people experience tinnitus (a buzzing, ringing, or roaring sound in the ear) ranging from mild to severe impairment. To date there is no effective therapy that seems to help the tinnitus sufferer.
- Trial name
- NCT00329524
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Hearing Aid, Tinnitus
Amplification and Tinnitus Masker Performance and Benefit for Adults With Hearing Loss and Tinnitus
This study is a Post-Market Clinical Investigation whose primary purpose is to evaluate hearing aid amplification and tinnitus masker performance for individuals with hearing loss and tinnitus.
- Trial name
- StarkeyPMCF (NCT07298499)
- Testing
- Hearing Aid, Tinnitus Masker
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Starkey Laboratories, Inc
Meniere Disease, Psychosocial Problem
Comprehensive Evaluation in Patients With Meniere's Disease
The aim of our study is to determine the severity of the disease in people with Meniere's Disease; physical conditions such as balance, posture, pain, physical activity level, neck joint range of motion, proprioception; to…
- Conditions
- Meniere Disease, Psychosocial Problem, Physical Disability, Quality of Life
- Trial name
- NCT05844657
- Testing
- Case report form, Tinnitus disability scale, A feeling of fullness and/or pressure in the ear
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Olfaction Disorders
Study of EEG and Nasal Stimulus in Olfactory Disorders
Neuroscent aims to analyze EEG signals induced by olfactory stimuli in individuals with normal and impaired olfactory functions, with a focus on patients with tinnitus.
- Trial name
- SENSO (NCT06589375)
- Testing
- Sniffin'Sticks
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Tinnitus
CBT-based Internet Intervention for Adults With Tinnitus in the United States
Nearly 50 million people in the U.S. experience tinnitus, of which about 20 million people have burdensome chronic tinnitus. Tinnitus can be very debilitating as many aspects of daily life can be affected, such as sleep, mood…
- Trial name
- NCT04004260
- Testing
- Internet-based Cognitive Behavior Therapy
- Where
- United States
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- Lamar University
U-VNS, Sham U-VNS
Blinding and Adverse Effects of Ultrasonic Vagus Nerve Stimulation (U-VNS)
The vagus nerve is a large nerve that runs from the gut to the brain. It consists of two main sections, left and right, and comprises a series of branches. One of these branches runs through the ear.
- Trial name
- BLAST (NCT07091812)
- Testing
- Ultrasound Vagus Nerve Stimulation (U-VNS)
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Profound Hearing Impairment
Positron Emission Tomography Imaging of Brain Reorganisation of the Central Auditory Cortex in Asymetrical Profound Deaf Patient With a Cochlear Implantation.
Our main objective is to study how the extent of reorganization of the central auditory system is related to the binaural integration in cochlear implanted subjects with asymmetric hearing loss.
- Trial name
- UniTEP (NCT03117413)
- Testing
- Positron emission tomography scan
- Where
- 2 sites in France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Jugular Vein Anomaly (Disorder), Diagnostic Self Evaluation
Evaluation Criteria, Diagnostic Criteria, Surgical Indications, and Establishment of Surgical Standards for "Cerebral Tinnitus Syndrome" Caused by Internal Jugular Vein Stenosis.
"Cerebral Tinnitus," also known as "cranial tinnitus," refers to the patient-reported perception of intracranial sounds. It often presents as "Cerebral Tinnitus Syndrome," which includes symptoms such as tinnitus with hearing…
- Conditions
- Jugular Vein Anomaly (Disorder), Diagnostic Self Evaluation, Nerosurgery, Assessment, Self
- Trial name
- NCT07560280
- Testing
- Atlas Transverse Process Mastoidectomy with Lysis and Perfusion
- Where
- China
- Volunteers
- 369 people, healthy volunteers welcome
- Sponsor
- Beijing Shijitan Hospital, Capital Medical University
Tinnitus, Subjective, Tinnitus
Inflammation in Tinnitus
Rationale: Tinnitus is the perception of sound without an external source. In the past decade, inflammation has been implicated in the pathophysiology of tinnitus.
- Conditions
- Tinnitus, Subjective, Tinnitus, Inflammation
- Trial name
- INFLATIN (NCT05268770)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Noise-Induced Hearing Loss
Micronutrients to Prevent Noise-induced Hearing Loss
Noise-induced hearing loss (NIHL) is a significant clinical, social, and economic issue. Studies in animals have allowed us to identify mechanisms contributing to NIHL, including direct mechanical trauma, free radicals formed in…
- Trial name
- NCT00808470
- Testing
- beta-carotene, vitamins C and E, magnesium
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Tinnitus
Tinnitus Sound Therapy Using Mobile Application.
Over the years Tinnitus Sound Therapy (TST) has been undergoing rigorous modification according to the availability of various technologies such as Hearing Aids, personal amplification devices, mp3 players, and now mobile phones.
- Trial name
- TST (NCT06104865)
- Testing
- Tinnitus Sound Therapy using (Resound Tinnitus relief) mobile application
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Dr. Basel Samman
Hearing Loss, Attention Impaired
Exploiting the Potential of Neural Attentional Control to Overcome Hearing Impairment
This study will improve the understanding of the cerebral mechanisms that underlie the control of auditory selective attention and evaluate the potential of neuromodulation to enhance neural attention control as a possible way to…
- Conditions
- Hearing Loss, Attention Impaired, Tinnitus
- Trial name
- NeurAttContr (NCT05513352)
- Testing
- tACS - transcranial alternating current stimulation, NF - Neurofeedback
- Where
- Switzerland
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Pulsatile Tinnitus (Diagnosis)
Role of the Radiologist in Management of Pulsatile Tinnitus
The aim of this study is to detect the role of interventional radiology in management of Pulsatile tinnitus and to detect the best imaging modality for Diagnosis.
- Trial name
- NCT05338684
- Testing
- Colour doppler,MSCT,MRI
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mohab Mohammed