Clinical trials: Tissue Adhesions
Dental Caries, Dental Plaque
Study of the Composition of Dental Plaque
This study will examine the composition of dental plaque-a naturally occurring substance that sticks to the teeth and can cause tooth decay and gum disease.
- Conditions
- Dental Caries, Dental Plaque, Periodontal Disease
- Trial name
- NCT00001726
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Tissue Adhesion, Gynecologic Surgery
The Assessment of the Use of Anti-Adhesion Agents to Prevent Pelvic Postoperative Adhesions
The aim of this study is to assess the safety and effectiveness of PROTAHERE Absorbable Adhesion Barrier to prevent pelvic postoperative adhesions.
- Trial name
- NCT04063085
- Testing
- PROTAHERE Absorbable Adhesion Barrier, Hyalobarrier Gel, No treatment
- Where
- Taiwan
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- SciVision Biotech Inc.
Infertility, Intrauterine Adhesions
Treatment of Infertility by Collagen Scaffold Loaded With Autologous Bone Marrow Stem Cells
Study of the treatment of infertility caused by severe intrauterine adhesions or endometrial dysplasia by collagen scaffold loaded with autologous bone marrow stem cells, and to provide clinical evidence for the treatment of…
- Conditions
- Infertility, Intrauterine Adhesions, Endometrial Dysplasia
- Trial name
- NCT02204358
- Testing
- autologous bone marrow stem cells
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Surgical Wound, Tissue Adhesion
Skin Closure With Tissue Adhesives vs. Subcuticular Suture After Robotic Urogynecologic Procedures
To compare skin closure via subcuticular suture versus tissue adhesive (Dermabond) in urogynecological robotic surgeries. The primary outcome is incision cosmesis at the 12 week follow up visit.
- Trial name
- NCT03891004
- Testing
- Subcuticular Skin Closure, Tissue Adhesives
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- St. John Hospital & Medical Center
Intrauterine Adhesion
Investigating the Association Between Diagnostic and Therapeutic Management Models and Prognosis of Intrauterine Adhesions Based on a Large-Scale Prospective Cohort Study
This research plan aims to explore a new diagnosis and treatment management model for intrauterine adhesions and verify its efficacy and feasibility through a multicenter real-world study.
- Trial name
- NCT07421908
- Testing
- Transcervical resection of adhesion, Uterine cavity stent, Traditional Chinese medicine for tonifying the kidney
- Where
- China
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- The Third Xiangya Hospital of Central South University
Healthy
Pharmacokinetics and Adhesion of Lidocaine Topical System 1.8% With Water Exposure
The objectives of this study are to evaluate the adhesion performance and pharmacokinetics of ZTlido (lidocaine topical system) 1.8% during swimming, showering, and under normal conditions.
- Trial name
- NCT04784728
- Testing
- Lidocaine topical system 1.8%
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Scilex Pharmaceuticals, Inc.
Fissure, Dental, Adhesion
Randomized Clinical Trial of Fissure Sealants Comparing Universal Adhesive With Etch-And-Rinse Adhesive After 24 Month
Objective: This randomized, controlled clinical study aimed to evaluate the performance of one universal adhesive applied with etch-and-rinse or self-etch strategy and one etch-and-rinse adhesive on fissure sealant retention over…
- Trial name
- NCT04837469
- Testing
- fissure sealant application
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Tissue Adhesions
Safety Study of Use of Hyaluronic Acid Gel To Prevent Intrauterine Adhesions In Hysteroscopic Surgery
Operations in the uterus are currently possible using a hysteroscope. One serious though rare complication of such procedures is the development of intra-uterine adhesions. There currently are no methods to prevent this.
- Trial name
- NCT01464528
- Testing
- Hyaluronan
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Intrauterine Adhesion, Scar
Clinical and Basic Research on the Necessity of Scar Tissue Resection During Intrauterine Adhesions
TCRA is an important surgical method to restore normal menstrual cycle and improve the outcome of pregnancy.However, postoperative intrauterine adhesion, uterine cavity deformation and difficulty in normal intimal growth…
- Trial name
- NCT05003869
- Testing
- Scar tissue is removed
- Where
- China
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Lili Cao
Healthy
Evaluation of Adhesion Quality and Irritation of an Alternate Second Generation Estradiol Transdermal System
The primary objective of this study was to compare the adhesive quality of the current Mylan estradiol placebo transdermal system, with that of an alternate second generation Mylan estradiol placebo transdermal system following a…
- Trial name
- NCT00650442
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Mylan Pharmaceuticals Inc
Adhesions, Cesarean Section
Seprafilm® Adhesion Barrier and Cesarean Delivery
A multicenter, randomized, controlled, single blinded study to evaluate the effectiveness of Seprafilm® Adhesion Barrier in reducing adhesion formation in cesarean deliveries.
- Conditions
- Adhesions, Cesarean Section, Delivery, Obstetric
- Trial name
- NCT00565643
- Testing
- modified sodium hyaluronic acid and carboxymethylcellulose
- Where
- 3 sites in United States
- Volunteers
- 753 people, healthy volunteers welcome
- Sponsor
- Winthrop University Hospital
Sliding Sign, Vesicouterin Thickness
Vesico-uterin Thickness and Sliding Sign in Term Pregnancies
In this study, our aim was to evaluate the relationship of the bladder to the uterus including vesicouterin thickness and sliding sign in term pregnancies with at least one previous cesarean section and compare to controls.
- Conditions
- Sliding Sign, Vesicouterin Thickness, Term Pregnancy, Adhesion; Bladder
- Trial name
- sliding sign (NCT07523698)
- Testing
- ultrasound evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Adana City Training and Research Hospital
Peritoneal Adhesions
Differences in Peritoneal Stem Cells in Women With and Without Adhesions After Gynaecological Surgery
Our study aims to characterise a possible pluripotent cell population in the abdomen responsible for peritoneal adhesions. We therefore want to take samples from women undergoing planned laparoscopic surgery with and without…
- Trial name
- NCT02847676
- Testing
- Tissue sample donation
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Pius-Hospital Oldenburg
Acne Vulgaris
Serum Intercellular Adhesion Molecule -1 in Acne Vulgaris Patients : Effect of Montelukast
The aim of this study is to: 1. Evaluation of serum soluble intercellular adhesion molecule-1 (sICAM-1) level in acne vulgaris and compare it to control group 2.
- Trial name
- NCT06340984
- Testing
- Montelukast 10 Mg Oral Tablet
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- South Valley University
Asherman Syndrome, Abortion Late
Prevalence of Intrauterine Adhesions After D&C With or Without Antiadhesion Gel After Abortion in Second Trimester.
Only patients who sign an informed consent will be included. Patients after a miscarriage in the 2nd trimester of pregnancy who need to perform an instrumental revision of the uterine cavity (RCUI, revisio cavi uteri…
- Trial name
- ADAB (NCT04671914)
- Testing
- Hyaluronic Acid 20 MG/ML Injectable Solution, Dilation and curretage
- Where
- 3 sites in Czechia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Institute for the Care of Mother and Child, Prague, Czech Republic
Glioma
Magnetic Resonance Elastography in Glioma: Exploring Tumor Stiffness and Adhesion
this study will investigate the relationship between tumor stiffness and adhesion in gliomas using MRE. By utilizing preoperative MRE and Intraoperative neuronavigation, followed by comprehensive molecular pathology analysis, we…
- Trial name
- NCT05990244
- Testing
- Magnetic Resonance Elastography, Assessment and Recording
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Atopic Dermatitis
Targeting Staphylococci in Atopic Dermatitis
The aim of the study is to deliver a better understanding of the molecular mechanisms used by S. epidermidis strains in their adhesion and colonization on the stratum corneum across a broad spectrum of atopic dermatitis in mild…
- Trial name
- NCT05502185
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- L'Oreal
Dental Plaque
Effect of Provisional-Crown Surface Coating on Biofilm Formation
Auto polymerizing poly methyl methacrylate (PMMA), and light initiated resin modified PMMAs, are commonly used for fabricating provisional restorations (PRs) during prosthetic treatment 1.
- Trial name
- NCT00254345
- Testing
- coating a dental restoration material ,polymethylmethacrylate, with liquid polish resin
- Where
- Israel
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Retained Products of Conception, Intrauterine Adhesion
Hysteroscopy Assisted Suction Curettage for Early Pregnancy Loss
Retained products of conception (RPOC) and intrauterine adhesions (IUA) may occur following suction curettage for early miscarriage and cause secondary infertility, recurrent pregnancy loss and pregnancy complications.
- Trial name
- NCT04637373
- Testing
- Hysteroscopy
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Intrauterine Adhesions
Seprafilm Slurry in the Prevention of Uterine Scarring in Patients Undergoing Hysteroscopic Myomectomy
Seprafilm is an FDA-approved temporary bioresorbable barrier that physically separates opposing tissue surfaces. The physical presence of the membrane separates adhesiogenic tissue while the normal tissue repair process takes…
- Trial name
- Seprafilm (NCT01632202)
- Testing
- Seprafilm, Sterile Saline Solution
- Where
- 2 sites in United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University