Clinical trials: Tissue Grafts
Mucosal Erosion, Gingival Recession
Patient-reported Outcomes of Donor Site Healing Using Different Palatal Protection Techniques
This study has been initiated to evaluate the question, "What is the best way to protect the palate after a gum graft is removed?" The overall objective is to determine if there is a difference in PROMs of donor site healing…
- Trial name
- NCT06892496
- Testing
- Visual Analog scale (VAS) questionnaire, Vacuum-formed retainer (VFR) technique, 3-D printed acrylic resin stent (3DS) technique
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Virginia Commonwealth University
Wounds and Injuries, Wound Infection
Long Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds
This study will evaluate the use of free autologous dermal fat grafting (also called free dermal fat autografting) to treat complex craniofacial wounds that have failed standard treatment and to understand how well these grafts…
- Conditions
- Wounds and Injuries, Wound Infection, Facial Bones Fracture, Soft Tissue Injuries
- Trial name
- FTFDT2 (NCT03880188)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dufresne, Craig, MD, PC
Gingival Recession, Lack of Keratinized Gingiva (Disorder)
Progenitor Potential of Mesenchymal Stem Cells in Palatal Tissue Harvested From Molar and Premolar Sites
The primary purpose of this protocol is to isolate, investigate and compare the regenerative and differentiation potential of mesenchymal stem cells (MSC's) in the gingival (gum) tissue harvested from two different locations from…
- Trial name
- NCT03570333
- Testing
- progenitor potential of Gingival Mesenchymal cells
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Horizontal Alveolar Ridge Resorption
Horizontal Ridge Augmentation in Maxillary Esthetic Zone Using Bovine Bone Graft Versus Extended Sticky Bone With Simultaneous Implant Placement
This research is designed to evaluate and compare the clinical and radiographic outcomes of bovine bone graft (Medpark) versus extended sticky bone used for horizontal augmentation of atrophied esthetic area of maxillary ridge…
- Trial name
- NCT07589426
- Testing
- oral surgery
- Where
- 2 sites in Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Androgenic Alopecia
Condensed Nanofat Grafting for Treatment of Androgenetic Alopecia
Nowadays, multiple treatment modalities have been applied clinically to treat androgenic alopecia, such as Follicular unit transplantation(FUT), finasteride, platelet-rich plasma injection(PRP), etc.
- Trial name
- NCT03506503
- Testing
- Nanofat grafting
- Where
- China
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Jinan University Guangzhou
Gingival Recession
Changes of Soft Tissue Grafting: A Randomized Study
To correct gum recession, patient's own tissue from the roof of the mouth is harvested and placed where there is root exposed. This is considered gold standard of treatment.
- Trial name
- NCT05633511
- Testing
- Split Mouth Design
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Tufts University
Papilla Reconstruction
Comparison of Connective Tissue Graft Versus Titanium Papillary Inserts in the Surgical Reconstruction of Interdental Papilla.
Aim and Objectives: The study aimed to evaluate the effectiveness of titanium inserts for interdental papilla reconstruction, comparing it with the Han and Takei technique using subepithelial connective tissue grafts.
- Trial name
- NCT07401667
- Testing
- TITANIUM INSERTS, CONNECTIVE TISSUE GRAFT
- Where
- India
- Volunteers
- 18 people
- Sponsor
- Dr R Viswa Chandra
Adhesions, Hand Fractures
Lipofilling in Operative Hand Fracture Treatment
Background: Hand fractures are a common clinical problem worldwide and account for a substantial economic burden and workload for experienced hand surgeons.
- Conditions
- Adhesions, Hand Fractures, Tenolysis
- Trial name
- NCT07815444
- Testing
- Lipofilling in Operative Treatment of Proximal Phalanx Fractures and Related Tenolysis
- Where
- Netherlands
- Volunteers
- 130 people
- Sponsor
- Jeroen Bosch Ziekenhuis
Pateint With Badely Decayed Anterior Teeth
Immediate Implant Placement With Immediate Loading With and Without Connective Tissue Graft
extraction of badely decayed anterior teeth immediate implant placement with immediate temporaization
- Trial name
- NCT03841851
- Testing
- sub epithelial connective tissue graft
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingival Recession
Effect of Orthodontic Treatment on the Stability of Pre-Orthodontic Recession Coverage
This study attempts to assess the effect of orthodontic treatment on the stability of pre-orthodontic recession coverage by connective tissue graft- a randomized controlled clinical trial and thus facilitate better evidence based…
- Trial name
- NCT03886051
- Testing
- Connective Tissue Graft before Orthodontic treatment, Orthodontic treatment only
- Where
- India
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Chronic Hepatitis B
A Clinical Study Evaluating the Pharmacokinetic Characteristics and Safety of AHB-137 Injection in Participants With Mild to Moderate Liver Dysfunction and Those With Normal Liver Function.
A clinical study evaluating the pharmacokinetic characteristics and safety of AHB-137 injection in participants with mild to moderate liver dysfunction and those with normal liver function.
- Trial name
- NCT07600788
- Testing
- AHB-137 injection
- Where
- 5 sites in China
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Ausper Biopharma Co., Ltd.
Gingival Recession, Localized
Theravex Oral and Theravex Tissue Care Plus in the Healing Process of Mucogingival Surgery
This clinical study assesses the efficacy of two novel bioactive solutions, Theravex Oral and Theravex Tissue Care Plus, in enhancing soft tissue healing after periodontal surgery.
- Trial name
- NCT07430670
- Testing
- Modified Free Gingival Graft (M-FGG), Theravex Bioactive Solutions (Tissue Care Plus and Oral)
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universidad Complutense de Madrid
Tooth Extraction
A Volumetric Analysis of Soft and Hard Tissue Healing for Ridge Preservation and Socket Seal After Tooth Extraction
This study will be a randomized clinical trial involving a total of 24 subjects. The investigators propose to recruit subjects into 2 groups: 1) Extraction treated with xenograft bone substitute (BioOss Collagen®) + collagen…
- Trial name
- NCT02844569
- Testing
- Xenograft bone substitute, Collagen dressing, 3D-collagen matrix
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Venous Leg Ulcer (VLU), Venous Leg Ulcers
Evaluating Intact Fish Skin Graft and Standard of Care Versus Standard of Care Alone in Nonhealing Venous Leg Ulcers
The purpose of this study is to determine the between-arm difference in the proportion of subjects achieving complete closure of hard-to-heal venous leg ulcers (VLU) between Intact Fish Skin Graft plus standard of care (IFSG/SOC)…
- Conditions
- Venous Leg Ulcer (VLU), Venous Leg Ulcers, Venous Leg, Nonhealing Venous Leg Ulcer
- Trial name
- THOR (NCT06693570)
- Testing
- Intact Fish Skin Graft (IFSG) + Standard of Care, Standard of Care
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Kerecis Ltd.
Degenerative Osteoarthritis, Post-traumatic; Arthrosis
Study of Subtalar Arthrodesis Using AlloStem® Versus Autologous Bone Graft
The purpose of this clinical trial is to evaluate the outcome of implanting AlloStem® graft with appropriate rigid internal fixation hardware as an alternative to autograft bone graft with rigid fixation in subtalar arthrodesis…
- Conditions
- Degenerative Osteoarthritis, Post-traumatic; Arthrosis, Rheumatoid Arthritis & Other Inflammatory Polyarthropathies, Rheumatoid Arthritis of Subtalar Joint
- Trial name
- NCT01413061
- Testing
- Subtalar Arthrodesis
- Where
- 5 sites in United States
- Volunteers
- 140 people
- Sponsor
- AlloSource
Peri-implant Mucositis, Peri-Implantitis
Comparison of CTG and T-PRF on Peri-Implant Soft Tissue
The present study aimed to increase the thickness of the gingiva and prevent possible crestal bone resorption by placing the CTG or T-PRF membrane under the mucosa immediately after the implant treatment in individuals with thin…
- Conditions
- Peri-implant Mucositis, Peri-Implantitis, Thin Gingiva
- Trial name
- NCT04042194
- Testing
- Placement of Implants and Thickening Peri-Implant Mucosa with T-PRF, Placement of Implants and Thickening Peri-Implant Mucosa with CTG
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Gingival Recession
Low Intensity Laser Therapy in Connective Tissue Graft for Root Coverage in Smokers
The aim of this study is to evaluate the influence of therapy with low-intensity laser technique associated with connective tissue graft for root coverage in smokers and compare the results with non- smokers
- Trial name
- NCT02995070
- Testing
- CTG, LLLT
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Kidney Transplantation
The Role of Connective Tissue Growth Factor in the Development of Kidney Disease After Organ Transplantation
This study will examine whether measurements of connective tissue growth factor (CTGF) and other cell proteins can identify which kidney transplant recipients are likely to develop chronic allograft nephropathy (CAN), a disease…
- Trial name
- NCT00056784
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Gingival Recession
Evaluation of Root Coverage After the Use of Coronally Advanced Flap Either With Advanced Paltelet Rich Fibrin or Subepithilial Connective Tissue Graft in Treatment of Miller Class I and II Gingival Recession.
patients with Miller class I , II gingival recession will be divided into 2 groups (control, intervention).the control one will receive coronally advanced flap with subepithililal connective tissue graft harvested from the palate…
- Trial name
- NCT03695549
- Testing
- CAF + (A-PRF), CAF+SCTG
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Autoimmune Disorders, Systemic Sclerosis
Phase I/II Study of AD-PluReceptor Plus Tafasitamab-cxix and Lymphodepleting Chemotherapy in Patients With Autoimmune Disorders
The goal of Safety Lead-In is to confirm the safety of tafasitamab when given to patients with SSc, SLE, and LN. The goal of Phase 1 is to find the recommended dose of AD-PluReceptor-NK cells in combination with tafasitamab and…
- Conditions
- Autoimmune Disorders, Systemic Sclerosis, Systemic Lupus Erythematosus, Lupus
- Trial name
- NCT06434363
- Testing
- Tafasitamab, Fludarabine phosphate, Cyclophosphamide
- Where
- 2 sites in United States
- Volunteers
- 47 people
- Sponsor
- M.D. Anderson Cancer Center