Clinical trials: Tobacco
Tobacco Use
Attitudes and Smoking Perceptions in the Real Environment
This study will measure appeal and reinforcement for different flavored little cigars/cigarillos (LCCs) in young adults in the laboratory and at-home, via ecological momentary assessment (daily smart-phone surveys)
- Trial name
- ASPIRE (NCT06617520)
- Testing
- Cigarillo flavor type
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Smoking, Alcohol Abuse
Dynamic Assessment and Referral System - Evaluation
The investigators study will use a randomized controlled design. Eligible and consenting participants will be randomly assigned to one of two conditions: (1) DARSSA Intervention condition, or (2) Minimal Intervention Control…
- Conditions
- Smoking, Alcohol Abuse, Drug Abuse
- Trial name
- DARSSA (NCT01153373)
- Testing
- Self-administered computerized assessment for tobacco, substance abuse, and alcohol use., Self-Administered Computerized Assessment and Counseling for Tobacco, Alcohol, and Substance Abuse
- Where
- United States
- Volunteers
- 758 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Tobacco Use Disorder
Chemical Dependency and Smoking Cessation: Patient's Views - 1
The purpose of this study is to asses patient views on smoking cessation and tobacco harm reduction during drug treatment.
- Trial name
- NCT00051883
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Tobacco Use, Tobacco Smoking
Tobacco Cessation at FDNY
At the Fire Department of the City of New York (FDNY) World Trade Center Health Program, 36% of participants in the low dose computed tomography (LDCT) lung cancer screening program are current smokers, despite referral to the…
- Conditions
- Tobacco Use, Tobacco Smoking, Tobacco Use Cessation
- Trial name
- NCT05997225
- Testing
- opt out enrollment, tailored counseling, varenicline started prior to target quit date, opt in enrollment, non-tailored counseling, varenicline started prior to target quit date
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Tobacco Use
CSD170202: A Study to Evaluate the Exposure to Tobacco Constituents From Two Moist Snuff Products
This study will evaluate exposure to tobacco constituents from two moist snuff products, and provide a basis for comparing mouth-level exposure (MLE) in moist snuff users after use of each of the two moist snuff products.
- Trial name
- NCT03158428
- Testing
- CSD170202AA, CSD170202AB
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- RAI Services Company
Saliva, Cortisol
Comparison of Saliva Biomarkers in Two Different Geographical Regions of Turkey
Periodontitis is a multifactorial, chronic inflammatory disease caused by many factors such as pathogenic microorganisms, host response, environmental and systemic factors.
- Conditions
- Saliva, Cortisol, Smoking, Tobacco, Periodontal Bone Loss
- Trial name
- NCT06809439
- Testing
- Non-Surgical Intervention, Saliva Collection (Baseline), Probing
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Cardiovascular Risk Factor, Nicotine Dependence
Vaping High vs. Low Nicotine E-Liquid
This study will examine the effects of electronic cigarette e-liquid nicotine content in a randomized, crossover clinical and behavioral pharmacology study of experienced adult e-cigarette users (N=36).
- Trial name
- NCT04047836
- Testing
- Low Nicotine E-Liquid, Medium or High Nicotine E-Liquid
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Tobacco Dependence
A Study of Novel Smoking Cessation Interventions in Current and Former Injection Drug Users
Cigarette smoking is very common in current and former injection drug users and is known to cause chronic lung diseases. Quitting smoking is proven to improve the health of people addicted to cigarettes. .
- Trial name
- NCT01334736
- Testing
- Usual care, Lung age, Contingency Management
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Tobacco Toxicant Exposure
Metabolism of Deuterated NNN in Smokeless Tobacco Users
The purpose of this study is to better understand how people break down a tobacco specific cancer-causing toxin called N'-nitrosonornicotine (NNN) that is present in smokeless tobacco and cigarettes.
- Trial name
- NCT02414477
- Testing
- Deuterated NNN
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Tobacco Use Cessation
Gender-Relevant Tobacco Cessation Among Women in Brazil
The overall goal of this renewal is three-fold: (1) to continue to sustain and strengthen the network; (2) to conduct a group randomized controlled trial to assess the efficacy of a theory-based, culturally- and gender-relevant…
- Trial name
- NCT03845413
- Testing
- Control, 12-home visits by the Community Health Worker + referring to an appointment for the participant to attend the tobacco cessation program
- Volunteers
- 338 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Current Smokers, Past Smokers
A Study on Analgesia and Related Outcomes for Patients With Tabacco Smoking
Numbers of postoperative PCA(Patient-Controlled Analgesia) related side effects among current, past and non smokers are determined by comparing and analyzing frequency distributions.
- Conditions
- Current Smokers, Past Smokers, Never Smokers
- Trial name
- NCT02266212
- Testing
- 5 ml arterial blood
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Veterans General Hospital.
Addictive Behavior, Alcohol Use Disorder (AUD)
Volitional Dysfunction in Self-control Failures and Addictive Behaviors
The aim of this project is to elucidate whether impairments of cognitive control, performance-monitoring, and value-based decision-making and dysfunctional interactions between underlying brain systems are mediating mechanisms…
- Conditions
- Addictive Behavior, Alcohol Use Disorder (AUD), Tobacco Use Disorder, Self-Control
- Trial name
- NCT04498988
- Testing
- Observational study without interventions
- Where
- Germany
- Volunteers
- 338 people, healthy volunteers welcome
- Sponsor
- Technische Universität Dresden
Drug Addiction, Nicotine Dependence
Assessing Top Down and Bottom Up Attention Mechanisms in Smokers Using Nicotine Nasal Spray
Background: Smoking is the leading cause of preventable death in the United States, and researchers are interested in gaining a better understanding of the perceived beneficial effects of nicotine to help improve treatment…
- Trial name
- NCT01136642
- Testing
- Nicotrol
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Tobacco Use
Evaluation of the Abuse Liability of Very Low Nicotine (VLN) Cigarettes
This study is designed to evaluate the abuse liability of very low nicotine cigarettes compared to nicotine gum and usual brand cigarettes
- Trial name
- NCT03559751
- Testing
- VLN cigarettes (A), Usual Brand Cigarettes (B), Nicotine gum (C)
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- 22nd Century Group, Inc.
Asthma, Smoking Cessation
Sustaining Smoking Cessation in Smokers With Kids With Asthma
Parents of Asthmatics Quit Smoking (PAQS-2) is a randomized controlled trial of a smoking cessation intervention for parents who smoke.
- Trial name
- PAQS2 (NCT00862368)
- Testing
- PAM, PAM-Enhanced/Asthma Counseling Phone Calls, Follow-Up Phone Calls - Child Wellness Topic
- Where
- 5 sites in United States
- Volunteers
- 573 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Nicotine Dependence
Transcranial Direct Current Stimulation in a Smoking Cessation Trial
The purpose of this study is to determine the effectiveness of transcranial direct current stimulation (tDCS) plus nicotine patch as a viable smoking cessation program for nicotine dependent smokers.
- Trial name
- tDCS (NCT01710410)
- Testing
- active transcranial Direct Current Stimulation
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Smoking, Tobacco Use Cessation
Tobacco Tactics Website for Operating Engineers
This is a clustered randomized control trial to test the Tobacco Tactics intervention among Operating Engineers (heavy equipment workers).
- Trial name
- BCBSM-OE (NCT01124110)
- Testing
- Tobacco Tactics Web-Based Intervention, 1-800-QUIT-NOW Telephone Hotline
- Where
- United States
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Cigarette Smoking
Comparison of Low Yield Cigarettes in African Americans vs. Whites
The investigators' general hypothesis is that African-Americans (AAs) smoke more for positive reinforcement from nicotine with a "peak-seeking" pattern of smoking (smoking individual cigarettes more intensively with greater…
- Trial name
- 6162-AAPK2 (NCT01058876)
- Testing
- Deuterated nicotine and cotinine
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Tobacco Use Disorder
A Bioequivalence Study of Three, 2 mg Nicotine Chewing Gums (Two Tests and One Reference) in Healthy Adult Smokers
This is a randomized, open-label, single-dose, three-period, crossover, single-center comparative bioavailability (BA) study under fasting condition in Chinese healthy male adult participants with a history of cigarette smoking.
- Trial name
- NCT02688374
- Testing
- Treatment A: Nicorette 2 mg coated mint gum, Treatment B: Nicotinell 2 mg coated mint gum, Treatment C: Nicotinell 2 mg coated fruit flavor gum
- Where
- China
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Smoking Cessation
Combining Default Choices and a Decision Aid to Improve Tobacco Cessation
The FIRST cluster randomized trial will evaluate the effect of 1) a training program encouraging general practitioners to offer smoking cessation treatment as a default choice to all current smokers consulting a general…
- Trial name
- FIRST (NCT04868474)
- Testing
- Training program and decision aid, Refresher course
- Where
- 2 sites in France, Switzerland
- Volunteers
- 287 people, healthy volunteers welcome
- Sponsor
- Center for Primary Care and Public Health (Unisante), University of Lausanne, Switzerland
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