Clinical trials: Tobacco Abuse
Tobacco Dependence
Topiramate Alone and in Combination With the Nicotine Patch for Smoking Cessation: A Pilot Study
Specific aims: 1. To obtain pilot data on 4-week continuous quit rates associated with 10 weeks of treatment with topiramate or placebo or topiramate plus nicotine patch for smoking cessation. 2.
- Trial name
- NCT00755716
- Testing
- Topiramate, Nicotine patch
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- UConn Health
Alcohol Abuse, Tobacco Use Disorder
Computer Adaptation of Screening, Brief MET Intervention to Reduce Teen Drinking
The goal of this project is to evaluate the feasibility, acceptability, and effect size of a new computerized Motivational Enhancement Therapy (cMET) intervention for alcohol-involved adolescents in primary care.
- Conditions
- Alcohol Abuse, Tobacco Use Disorder, Substance Use
- Trial name
- NCT01881841
- Testing
- cMET
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Boston Children's Hospital
Tobacco Use Disorder
Effectiveness of Using Tobacco Free Snuff in Reducing Negative Effects of Smokeless Tobacco Use
Though spit tobacco is smokeless, it still affects the cardiovascular system and may be associated with heart disease, stroke, and high blood pressure.
- Trial name
- NCT00218270
- Testing
- Tobacco free snuff
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Tobacco Dependence, Cessation of Smoking
Effectiveness of an E-mail Tracking Intervention Among the Continued Abstinence of Tobacco Consumption
Objectives. To evaluate the effectiveness and cost effectiveness of clinical practice guide based intervention with two face-to-face visits and e-mail tracking compared to brief advice to obtain continued smoking abstinence at 6…
- Trial name
- TABATIC (NCT01494246)
- Testing
- electronic mail
- Where
- Spain
- Volunteers
- 1,064 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Limited Stage Small Cell Lung Cancer, Recurrent Small Cell Lung Cancer
Enhanced Quitline Intervention in Smoking Cessation for Patients With Non-Metastatic Lung Cancer
This randomized clinical trial studies enhanced quitline intervention in smoking cessation for patients with non-metastatic lung cancer.
- Conditions
- Limited Stage Small Cell Lung Cancer, Recurrent Small Cell Lung Cancer, Stage IA Non-small Cell Lung Cancer, Stage IB Non-small Cell Lung Cancer
- Trial name
- NCT01457469
- Testing
- questionnaire administration, quality-of-life assessment, counseling intervention
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Wake Forest University Health Sciences
Tobacco Use Disorder
Bupropion as an Adjunct to the Nicotine Patch Plus CBT
Existing and new pharmacotherapies along with prevention efforts are key to improving smoking cessation rates and reducing the premature morbidity and mortality associated with tobacco use.
- Trial name
- NCT00142831
- Testing
- Pharmacotherapies for Smoking Cessation
- Where
- United States
- Volunteers
- 293 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Cigarette Smoking, Nicotine Dependence
Reducing Tobacco Use Disparities Among Low-Income Adults
Most smokers, especially those who are poor, do not receive smoking cessation treatment during their healthcare visits. This study is evaluating a novel population health management intervention for low-income smokers.
- Trial name
- NCT03077737
- Testing
- Choose to Change, Enhanced usual care
- Where
- United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Tobacco Use, Tobacco Smoking
Evaluation of a Brief Tobacco Intervention in the US Military
While the military has taken steps to reduce tobacco use over the past two decades, over a quarter of new military recruits report regular tobacco use prior to enlistment.
- Conditions
- Tobacco Use, Tobacco Smoking, Smoking, Cigar, Smoking, Pipe
- Trial name
- NCT03196102
- Testing
- BTI, Cigarette smoking military tailored pamphlet, Standard smoking cessation intervention
- Where
- United States
- Volunteers
- 2,999 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Tobacco Use Disorder
Treating Schizophrenic Smokers: Effects on Craving, Cues and Withdrawal
This is a clinical research protocol to study the efficacy of combined varenicline (Chantix) and motivational interviewing (MI) for smoking cessation in a sample of smokers who have been diagnosed with schizophrenia or…
- Trial name
- NCT00781755
- Testing
- varenicline, Adaptation of Motivational Interviewing
- Where
- United States
- Sponsor
- VA Boston Healthcare System
Schizophrenia, Substance Abuse
Screening Protocol for Research Participants
The Screening Protocol is a system devised to evaluate potential research participants for National Institute on Drug Abuse/Maryland Psychiatric Research Center (NIDA/MPRC) studies.
- Conditions
- Schizophrenia, Substance Abuse, Cocaine Abuse, Tobacco Use Disorder
- Trial name
- ScreenProt (NCT01010620)
- Testing
- Various Screening psychiatric and medical assessments
- Where
- United States
- Volunteers
- 523 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Tobacco Use Disorder
Clinical Effort Against Secondhand Smoke (CEASE) Program or Standard Care in Helping Parents Stop Smoking
RATIONALE: The Clinical Effort Against Secondhand Smoke (CEASE) program may be more effective than standard care in increasing the number of parents who stop smoking.
- Trial name
- NCT00664261
- Testing
- smoking cessation intervention, cancer prevention, counseling intervention
- Where
- United States
- Volunteers
- 3,000 people
- Sponsor
- Massachusetts General Hospital
Smoking, Nicotine Dependence
E-Cigarettes: Dynamic Patterns of Use and Health Effects
The proposed research will provide in-depth, longitudinal data, based on real-time reports, which will address key priorities for the FDA including, increased understanding of the relations between electronic cigarette (e-cig)…
- Trial name
- NCT02527980
- Testing
- No intervention: observation only
- Where
- 2 sites in United States
- Volunteers
- 422 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Nicotine Dependence
Effects of Chantix on Relapse Prevention for Smoking Cessation
The goal of the proposed study is to validate an experimental paradigm to assess medication effects on smoking relapse following a brief (3-day) monitored period of smoking abstinence and a programmed cigarette lapse.
- Trial name
- NCT00948649
- Testing
- Varenicline
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Smoking Cessation, Tobacco Use Disorder
Virtual Reality (VR)and Mobile-Based Smoking Cessation in Breastfeeding Mothers
This randomized controlled trial was conducted to evaluate the effect of an educational video delivered through virtual reality (VR) glasses and a mobile application on smoking cessation behavior among breastfeeding mothers.
- Conditions
- Smoking Cessation, Tobacco Use Disorder, Breast Feeding
- Trial name
- NCT07775755
- Testing
- Virtual Reality and Mobile Application-Based Smoking Cessation Education
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Smoking, Smoking Cessation
Connect to Quit for Smoking
The purpose of this research study is to examine the effectiveness of an intervention designed to reduce smoking in low income veterans within a regional United States Veterans Administration(VA) health care system.
- Trial name
- CTQ (NCT01299896)
- Testing
- Coordinated Care, Usual Care
- Where
- United States
- Volunteers
- 633 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Tobacco Dependence
Varenicline in Combination With Nicotine Replacement Therapy for Smoking Cessation
The purpose of this study is to test whether the addition of a nicotine patch to varenicline increases smoking cessation success rate and whether the combination is safe.
- Trial name
- NCT01444131
- Testing
- Varenicline, Nicotine Patch
- Where
- 7 sites in South Africa
- Volunteers
- 446 people
- Sponsor
- University of Stellenbosch
Tobacco Use Disorder, Nicotine Dependence
TUBSIS 2.0 - Tobacco Use Behavioral Support and Intervention System
Background: Tobacco smoking and vaping remains public health concern, with many adults continuing to experience difficulties accessing appropriate support for smoking cessation in Switzerland and Türkiye.
- Conditions
- Tobacco Use Disorder, Nicotine Dependence, Vaping, Smoking Tobacco
- Trial name
- TUBSIS_2_0 (NCT07568483)
- Testing
- TUBSIS 2.0
- Where
- Switzerland
- Volunteers
- 406 people
- Sponsor
- University of Zurich
Nicotine Dependence
Drug /Cue Interactions In Alcohol-Tobacco Comorbidity
The purpose of this study is to determine how people react to different combinations of alcohol and nicotine.
- Trial name
- NCT00816231
- Testing
- Tobacco, Alcoholic Beverage
- Where
- United States
- Volunteers
- 244 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Tobacco Dependence
Smoking Cessation With Smokeless Tobacco, Nicotine Tablets and Nicotine Patches
To test if smokeless tobacco is more effective than nicotine buccal tablets in smoking cessation compared with a control group with low dose nicotine patches.
- Trial name
- NCT00313105
- Testing
- Smokeless tobacco (Oliver Twist pellets), smoking cessation counseling
- Where
- Denmark
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
Tobacco Use Disorder
Effect of Transcranial Direct Current Stimulation (tDCS) on Tobacco Consumption
The primary purpose of the protocol is to evaluate the effect of repeated application for 5 consecutive days of a real tDCS compared to the application of a placebo tDCS (sham procedure) on the evolution of tobacco consumption in…
- Trial name
- TABELEC (NCT01930422)
- Testing
- tDCS procedure
- Where
- France
- Volunteers
- 34 people
- Sponsor
- University Hospital, Toulouse
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