Clinical trials: Tobacco Cigarette Smoking
Tobacco Dependence, Schizophrenia
Cigarette Smoking in Smokers With and Without Schizophrenia
Higher rates and severity of tobacco dependence in people with schizophrenia, as compared with the general population, contribute to the lower life expectancy seen in this population.
- Trial name
- NCT04001114
- Testing
- Sampling Research Cigarettes
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Cigarette Smoking, Mindfulness
Mindfulness Training for Smokers Online Feasibility Study
The Mindfulness Training for Smokers Online Feasibility Study is a pilot study designed to test Mindfulness Training for Smokers in an Internet format with phone counseling.
- Trial name
- MTS3 (NCT02164656)
- Testing
- mindfulness for smokers
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Cigarette Smoking
Mechanisms of the Nicotine Metabolism Effect on Tobacco Dependence
The purpose of the study is to learn more about tobacco dependence and nicotine metabolism in African-Americans and whites, by studying to see if how fast a person metabolizes nicotine (how the body breaks down nicotine into…
- Trial name
- NMR (NCT01627392)
- Testing
- Smoking abstinence
- Where
- United States
- Volunteers
- 305 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
College Student Drinking, Eating Disorder
Your Health in On Click
A health education program was provided to higher education students aged between 18 and 25 years. Students were recruited either by posters and leaflets on campus, or during their mandatory medical survey at the University…
- Conditions
- College Student Drinking, Eating Disorder, Stress, Psychological, Burn Out Syndrome
- Trial name
- TS1C (NCT03218670)
- Where
- France
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Marie-Pierre TAVOLACCI
Nicotine Dependence
Smart Olfaction App to Reduce Relapse
The proposed project aims to refine and test a novel biobehavioral smoking cessation intervention that integrates the strategic application of olfactory stimulation to reduce cigarette craving with an established smartphone-based…
- Trial name
- SOARR (NCT07007195)
- Testing
- Ad Libitum Use followed by Instructed Use of the Inspire Device, Instructed Use followed by Ad Libitum Use of the Inspire Device, Smart-T Smoking Cessation App with the Inspire Device Condition
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- University of Houston
Cigarette Smoking, Nicotine Dependence
Effects of Very Low Nicotine Content Cigarettes Among Adults Who Smoke Daily in South Korea
The goal of this clinical trial is to learn how switching to very low nicotine content (VLNC) cigarettes affects smoking behavior and nicotine exposure among adults in South Korea who smoke conventional cigarettes daily.
- Trial name
- NCT07755891
- Testing
- SPECTRUM cigarettes
- Where
- South Korea
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Sung-il Cho
Chronic Pain, Smoking, Cigarette
Low Nicotine Cigarettes, Smoking, and Chronic Pain
The purpose of this study is to evaluate the effects of switching to very low nicotine content (VLNC) cigarettes versus normal nicotine content (NNC) cigarettes on experiences with craving, withdrawal, and pain among individuals…
- Trial name
- VLNCPain (NCT05032755)
- Testing
- SPECTRUM NRC 102/103 investigational cigarettes, SPECTRUM NRC 600/601 investigational cigarettes
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Duke University
ADHD
Prevention of Cigarette Smoking in Attention Deficit Hyperactivity Disorder (ADHD) Youth With Concerta
This study will consist of a six-week open-label treatment period with an extended duration methylphenidate (OROS MPH) followed by subsequent monthly visits for 24 months in a large sample of youths aged 12-17 who meet Diagnostic…
- Trial name
- NCT00181714
- Testing
- methylphenidate HCl (Concerta)
- Where
- United States
- Volunteers
- 203 people
- Sponsor
- Massachusetts General Hospital
Smoking, Tobacco Use
BAT3221032: A Study to Evaluate the Effects of Switching From Cigarette Smoking to Using One of Five Variants of a Heated Tobacco Product on Biomarkers of Exposure and Biomarkers of Potential Harm in Healthy Subjects
This is a randomized, controlled, multi-center, open-label, 8-cohort parallel group study to assess changes in select biomarkers of exposure (BoE) and biomarkers of potential harm (BoPH) in generally healthy smokers switching to…
- Conditions
- Smoking, Tobacco Use, Tobacco Smoking
- Trial name
- NCT05142436
- Testing
- Product A: Non-Combusted Cigarette Variant 42001402 and product use Mode B, Product B: Non-Combusted Cigarette Variant 42001399 and product use Mode B, Product C: Non-Combusted Cigarette Variant 42001401 and product use Mode B
- Where
- 18 sites in United States
- Volunteers
- 806 people, healthy volunteers welcome
- Sponsor
- British American Tobacco (Investments) Limited
Smoking, Tobacco Smoking
Effect of Packaging on Smoking Perceptions and Behavior
The investigators are addressing two critical areas identified by the FDA: the impact of cigarette packaging and labeling on consumer perceptions and on smoking behavior; and the effectiveness of graphic warning labels on…
- Trial name
- CASA (NCT02676193)
- Testing
- Effect of Packaging on Smoking Perceptions and Behavior
- Where
- United States
- Volunteers
- 359 people
- Sponsor
- University of California, San Diego
Anxiety Disorders, Anxiety
Personalized Feedback for Smokers With Elevated Anxiety Sensitivity
This project will develop and refine a computer-delivered integrated Personalized Feedback Intervention (PFI) that directly addresses smoking and anxiety sensitivity (AS).
- Conditions
- Anxiety Disorders, Anxiety, Tobacco Dependence, Smoking, Cigarette
- Trial name
- NCT03382093
- Testing
- Personalized Feedback Intervention, Smoking Information Control
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- University of Houston
Cigarette Smoking
Effects of Deep Breathing Exercise on Pulmonary Function, Perceived Stress and Physical Fitness Among Healthy Smokers
Effects of deep breathing exercise on pulmonary function, perceived stress and physical fitness among healthy smokers.
- Trial name
- NCT06032793
- Testing
- Breathing exercises
- Where
- Pakistan
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Cigarette Smoking
Financial Incentives for Smoking Cessation Among Mothers
Investigators will examine whether adding financial incentives and nicotine replacement dual therapy to current best practices for smoking cessation (i.e.
- Trial name
- NCT05740098
- Testing
- Best Practices, Financial Incentives, Nicotine Replacement Therapy
- Where
- United States
- Volunteers
- 198 people
- Sponsor
- University of Vermont
Smoking
Smartphone Application for Smoking Cessation
The purpose of this study is to test the effectiveness of a smartphone application for smoking cessation in smokers ages 18 to 65 years.
- Trial name
- NCT02134509
- Testing
- Experimental App, Active Comparator App
- Where
- United States
- Volunteers
- 511 people, healthy volunteers welcome
- Sponsor
- Yale University
Cigarette Smoking, Methadone Maintenance
Pilot Study of Nicotine Nasal Spray and Varenicline on Smoking in Methadone-Maintained Patients
The objective is to provide a preliminary test of the ability of two pharmacological treatments, the nicotine nasal spray and varenicline, relative to placebos, to reduce smoking during the 4 hours following methadone dosing.
- Trial name
- NCT02147132
- Testing
- Nicotine Nasal Spray, Varenicline
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Cincinnati
Tobacco Use Disorder
Low Nicotine Content Cigarettes in Vulnerable Populations: Opioid Use Disorder
Prevalence of smoking among individuals with opioid use disorder (OUD) is six-fold that of the general US adult population. The mortality rate of opioid-dependent smokers is four times that of opioid-dependent nonsmokers, and…
- Trial name
- NCT04092101
- Testing
- Cigarettes with varying nicotine content, E-Cigarettes
- Where
- 2 sites in United States
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Tobacco Use Disorder
The Study of AZD8529 for Smoking Cessation in Female Smokers
To evaluate the efficacy and safety of AZD8529 for smoking cessation in female smokers.
- Trial name
- NCT02401022
- Testing
- AZD8529
- Where
- 9 sites in United States
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Smoking, Tobacco, Placenta Diseases
Effects of Smoking on Placenta and Lactation
Maternal smoking during pregnancy although it is known to be associated with fetal growth restriction, it's effect on postpartum breastfeeding is not yet clear.
- Conditions
- Smoking, Tobacco, Placenta Diseases, Breastfeeding, Fetal Conditions
- Trial name
- NCT06456645
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Manisa Celal Bayar University
Smoking ( Cigarette)
Effect of Buteyko Breathing Exercise Combined With Postural Stability Exercises on Maximal Oxygen Consumption in Young Adult Smokers
Background: Smoking is one of the most significant risk factors for respiratory diseases, affecting both lung function and overall respiratory health.
- Trial name
- BBE PSE VO2max (NCT07257783)
- Testing
- Buteyko breathing exercise combined with postural stability exercises
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Yasmeen Alaa Abd El-Hamied Ahmeed
Tobacco Use Disorder
Cigarette and E-cigarette Flavors Manipulations in the Experimental Tobacco Marketplace
This is a one-session study that participants complete remotely including consent, Experimental Tobacco Marketplace purchases, and assessments to examine the effects of cigarette and e-cigarette flavors on cigarette demand and…
- Trial name
- NCT05110872
- Testing
- Cigarette flavor restricted and e-cigarette flavor restricted, Cigarette flavor restricted and e-cigarette flavor unrestricted, Cigarette flavor unrestricted and e-cigarette flavor restricted
- Where
- United States
- Volunteers
- 302 people
- Sponsor
- Virginia Polytechnic Institute and State University