Clinical trials: Tobacco Consumption
Hiv, Tobacco Smoking
Accelerated Transcranial Magnetic Stimulation (TMS) for Smoking Cessation in People Living With HIV/AIDS (PLWHA)
To demonstrate whether four sessions of TBS improves attentional bias and craving in PLWHA smokers compared to four sessions of sham stimulation.
- Trial name
- NCT05295953
- Testing
- TBS
- Where
- 2 sites in United States
- Volunteers
- 4 people
- Sponsor
- Gopalkumar Rakesh
E-cigarette
Acute Health Effects of Short-term Use of E-cigarettes on Pulmonary and Cardiovascular System
The goal of our study was to assess acute, short term respiratory (airflow, FeNO, O2 saturation, exhaled air temperature) and cardiovascular (heart rate, blood pressure) responses to smoking an e-cigarette in exclusive e-smokers…
- Trial name
- NCT03742700
- Testing
- Cigarette smoking, E-cigarette use, Simulation of the use of e-cigarette
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medical University of Silesia
Tobacco Smoking
Development of a Tailored Smoking Cessation Program for Individuals With HIV Infection in Washington, D.C.
Morbidity and mortality from smoking-related diseases among people living with HIV (PLWH) in the U.S. surpasses that due to HIV itself. Conventional smoking cessation treatments have not demonstrated strong efficacy among PLWH.
- Trial name
- NCT04594109
- Testing
- Tailored behavioral counseling, Standard of Care
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Colorado State University
Tobacco Smoking
Testing the Decoy Effect to Increase Tobacco Treatment Uptake
Prior research has shown that the context in which program options are presented to consumer impacts consumer choice (known as the 'decoy effect').
- Trial name
- NCT04200157
- Testing
- Online survey
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- NYU Langone Health
Tobacco Dependence
Predictors of Treatment Outcome for Smokers With and Without Schizophrenia
The primary purpose of this investigation is to determine the predictive value of task persistence as measured by a mirror tracing task.
- Trial name
- NCT00501007
- Where
- United States
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Tobacco Use Disorder, Schizophrenia
Combining rTMS With Varenicline to Prevent Smoking Lapse in Schizophrenia
Tobacco smokers with schizophrenia are known to be resistant smokers, with high rates of smoking and inability to quit in the long-term, often related to smoking relapse.
- Conditions
- Tobacco Use Disorder, Schizophrenia, Cognitive Functioning, Craving
- Trial name
- NCT03497299
- Testing
- Active rTMS (20Hz)
- Sponsor
- Centre for Addiction and Mental Health
Tobacco Use Cessation
Emergency Department Smoking Cessation Study
Tobacco smoke claims approximately 6000 lives annually in BC. In this study, the investigators will determine whether referring smoking patients from the Vancouver General Hospital Emergency Department to the investigators…
- Trial name
- NCT01454375
- Testing
- Referral to QuitNow Services
- Where
- Canada
- Volunteers
- 1,301 people
- Sponsor
- University of British Columbia
Smoking Cessation, Tobacco Dependence
De-nicotinised Cigarettes Study
The aim of this study is to determine if using a behavioural replacement for smoking (de-nicotinised cigarettes; DNCs), in addition to standard treatment during the first two weeks after the target quit date, can reduce urges to…
- Trial name
- Denic (NCT01250301)
- Testing
- De-nicotinised cigarettes + standard treatment, Standard Treatment
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Tobacco Use Cessation
Enhancing Quitline Services for African American Smokers
This study proposes to test the value of a culturally specific program for African American smokers to quit smoking.
- Trial name
- NCT03064971
- Testing
- Standard Care, smoking cessation DVD, PTF DVD
- Where
- United States
- Volunteers
- 1,050 people, healthy volunteers welcome
- Sponsor
- Case Comprehensive Cancer Center
Tobacco Abstinence
Varenicline For Smokers In Recovery From Alcohol Dependence
The goal of this proposal is to explore the potential effectiveness of varenicline to treat tobacco dependence among recovering alcoholic smokers who, as a group, are at high risk for tobacco-caused morbidity and mortality.
- Trial name
- NCT01092702
- Testing
- Varenicline
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Alcohol Use Disorder, Cigarette Smoking
Semaglutide for Alcohol Use Disorder
This is an early-Phase II human laboratory trial using a randomized, placebo-controlled, dose-ranging design to investigate the effects of semaglutide, a GLP-1 receptor agonist, on alcohol-related outcomes in adults with alcohol…
- Trial name
- NCT05520775
- Testing
- Semaglutide
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Tobacco Use Disorder, Smoking
Electronic Cigarettes (E-cigarettes) as a Harm Reduction Strategy
The purpose of this study is to examine the feasibility of using e-cigarettes as a method for harm reduction and the effects of providing e-cigarettes (or placebo e-cigarettes) on smoking outcomes.
- Trial name
- NCT02628964
- Testing
- e-cigarettes
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Nicotine Dependence
Pharmacokinetics, Subjective Effects, and Abuse Liability of Nicotine Salt-Based Vaping Products With Tobacco or Unflavored E-liquids, SALTVAPE Study
This trial studies activity of time (pharmacokinetics), subjective effects, and abuse liability of nicotine salt-based vaping products with tobacco or e-liquids.
- Trial name
- NCT04231539
- Testing
- Nicotine, Vaporizer Device, Salt-HIgh Nicotine Unflavored (Product B)
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
Nicotine Withdrawal, Marijuana Dependence
Medications Development for the Treatment of Cannabis Related Disorders
The primary objective of this application is to test the neurobehavioral mechanisms and effects of aprepitant as a new cessation agent for cannabis, tobacco or both.
- Conditions
- Nicotine Withdrawal, Marijuana Dependence, Cannabis Dependence, Nicotine Dependence
- Trial name
- MTC (NCT01204723)
- Testing
- Active Aprepitant
- Where
- 2 sites in United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Nicotine Addiction
Quantitation of Human Cerebral Nicotinie Receptors With 2[18F]FA-85380 and PET Healthy Non-smokers and Ex-Smokers and in Heavy and Light Situational Smokers
Background: Central nicotinic acetylcholine receptors (nAChRs) are primary targets for the action of nicotine. In addition to being involved in tobacco dependence, they are also involved in a variety of brain disorders, including…
- Trial name
- NCT01038245
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Tobacco Use Disorder
Project 3, Study 2: Extended Exposure to Low Nicotine Content Cigarettes in People With Current Affective Disorders
This study will examine extended exposure to cigarettes varying in nicotine content among disadvantaged women. Adults with affective disorders are at increased risk for smoking, nicotine dependence, and using high nicotine yield…
- Trial name
- NCT02232737
- Testing
- Very low nicotine content cigarettes
- Where
- 2 sites in United States
- Volunteers
- 775 people, healthy volunteers welcome
- Sponsor
- Brown University
Tobacco Dependence
Single-dose Nicotine Pharmacokinetics With a New Oral Nicotine Replacement Product
A comparison of three products for oral nicotine replacement with respect to pharmacokinetics after single-dose of nicotine.
- Trial name
- NCT01084603
- Testing
- Oral Nicotine, NiQuitinTM Nicotine Lozenge, Nicorette® Nicotine Gum
- Where
- Sweden
- Volunteers
- 45 people
- Sponsor
- McNeil AB
Tobacco Dependence
Effects of Naltrexone on Nicotine Reinforcement
Despite preclinical evidence supporting the role of the endogenous opioid system in the reinforcing effects of nicotine, the efficacy of the opioid antagonist naltrexone (NTX) as a tobacco dependence treatment remains unresolved.
- Trial name
- NCT00270231
- Testing
- Naltrexone
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- University of Pennsylvania
Diabetes Mellitus, Tobacco Use Cessation
Feasibility of a Diabetes Specialist Nurse-led Smoking Cessation Intervention
The goal of this clinical trial is to assess the feasibility and acceptability of a multi-component smoking cessation intervention for individuals living with diabetes which is delivered by diabetes specialist nurses.
- Trial name
- NCT05920096
- Testing
- Diabetes specialist nurse-led multi-component smoking cessation intervention, Health Promotion and Disease Prevention Directorate's one-to-one smoking cessation service (standard care)
- Where
- Malta
- Volunteers
- 91 people
- Sponsor
- University of Malta
Smoking, Smoking Behaviors
CSD190203: A Study to Determine Subject Puffing Patterns of an Electronic Nicotine Delivery System in an Ambulatory Setting
This study will be a single-center, randomized, controlled, open-label, parallel 2-cohort study to evaluate the puffing patterns of individuals switching from a similar usual brand (UB) Electronic Nicotine Delivery System (ENDS)…
- Conditions
- Smoking, Smoking Behaviors, Tobacco Use, Tobacco Smoking
- Trial name
- NCT04104152
- Testing
- CSD1902-11, CSD1902-12, CSD1902-13
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- RAI Services Company
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