Clinical trials: Tobacco Consumption
Bladder Cancer, Cervical Cancer
Health Education Counseling With or Without Bupropion in Helping African Americans Stop Smoking
RATIONALE: A stop-smoking plan that includes health education counseling and bupropion may help African-American smokers stop smoking.
- Conditions
- Bladder Cancer, Cervical Cancer, Esophageal Cancer, Gastric Cancer
- Trial name
- NCT00666978
- Testing
- smoking cessation intervention, bupropion hydrochloride, gene expression analysis
- Where
- 2 sites in United States
- Volunteers
- 540 people
- Sponsor
- Lisa Sanderson Cox, PhD
Nicotine Addiction
Comparative Effectiveness of Cystine Versus Nicotine Replacement Therapy
A pragmatic, single blinded, randomized, controlled non-inferiority trial of Cytisine versus Nicotine Replacement Therapy for continuous abstinence is conducted in the government run primary health hospitals in Mongolia.
- Trial name
- NCT04126135
- Testing
- Cytisine, Nicotine Replacement Therapy (NRT)
- Where
- Mongolia
- Volunteers
- 1,307 people
- Sponsor
- Loma Linda University
Tobacco Use Cessation
Interest of an Auriculotherapy Session in Smoking Cessation
The aim of the study is to show that auriculotherapy is effective in smoking cessation.
- Trial name
- StopAuric (NCT04880330)
- Testing
- Cryo-Auriculotherapy
- Where
- 3 sites in France
- Volunteers
- 90 people
- Sponsor
- Hopital Foch
Smoking, Tobacco Use
CSD201001: Study to Assess Elements of Abuse Liability for Three Nicotine Pouches
This is a two-site, open-label, randomized, 5-way cross-over study designed to evaluate elements of abuse liability (AL) including subjective effects and physiological measures (pharmacodynamics [PD]) and plasma nicotine uptake…
- Conditions
- Smoking, Tobacco Use, Tobacco Smoking
- Trial name
- NCT05129657
- Testing
- Product A, Product B, Product C
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- RAI Services Company
Bladder Cancer, Cervical Cancer
Bupropion in Helping Adults Stop Smoking
RATIONALE: Bupropion may help people stop smoking by decreasing the symptoms of nicotine withdrawal. Giving bupropion over a longer period of time may be effective in helping people stop smoking.
- Conditions
- Bladder Cancer, Cervical Cancer, Esophageal Cancer, Gastric Cancer
- Trial name
- NCT00534001
- Testing
- bupropion hydrochloride
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Roswell Park Cancer Institute
Smoking
Medical Student INtervention to Promote Effective Nicotine Dependence and Tobacco HEalthcare
Background: Smoking counselling during hospitalisation with post-discharge follow-up increases quitting. However, provision of cessation care for hospitalised patients is suboptimal.
- Trial name
- MIND-THE-GAP (NCT02601599)
- Testing
- Motivational interviewing
- Where
- Ireland
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Royal College of Surgeons, Ireland
Smoking, Smoking Behaviors
CSD190601: A Study to Determine Subject Puffing Patterns of Electronic Nicotine Delivery Systems in an Ambulatory Setting
This study will be a single-center, controlled, open-label, parallel two-study-group investigation to evaluate the puffing patterns of healthy adult consumers of tobacco products switching from a usual brand (UB) Electronic…
- Conditions
- Smoking, Smoking Behaviors, Tobacco Use, Tobacco Smoking
- Trial name
- NCT04308434
- Testing
- CSD190601-11, CSD190601-12, CSD190601-13
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- RAI Services Company
Periodontitis, Gingivitis
Evaluation of the Effect of Smoking on Pyroptosis in Periodontal Pathogenesis
This study investigates the impact of smoking on pyroptosis and inflammatory signaling pathways in systemically healthy individuals with various periodontal conditions.
- Conditions
- Periodontitis, Gingivitis, Periodontal Diseases, Smoking ( Cigarette)
- Trial name
- NCT07563192
- Where
- Turkey (Türkiye)
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Tobacco Prevention, Environmental Tobacco Smoke Exposure
The Impact of a Tobacco Control Intervention in African-American Families
The purpose of this randomized control trial is to evaluate the effects of a multi-component intervention aimed at: 1. preventing tobacco initiation in youth 2. promoting anti-tobacco socialization in the home 3.
- Conditions
- Tobacco Prevention, Environmental Tobacco Smoke Exposure, Tobacco Cessation
- Trial name
- NCT01164306
- Testing
- LifeSkills Training, Healthy Lifestyle Behavior Choices, NRT and Motivational Interviewing (MI)
- Where
- United States
- Volunteers
- 688 people, healthy volunteers welcome
- Sponsor
- Augusta University
Smoking Cessation, Nicotine Dependence
Study Assessing Efficacy and Safety of NFL-101 as a Tobacco Cessation Therapy
CESTO 2 is a 318 participants, 3-arm, multicentric, randomized, double-blind, placebo-controlled Phase II clinical trial. The main objectives are to select the most efficient dose and to assess long-term efficacy of NFL-101…
- Trial name
- CESTO2 (NCT04571216)
- Testing
- NFL-101 dose 1, NFL-101 dose 2
- Where
- 9 sites in France
- Volunteers
- 318 people, healthy volunteers welcome
- Sponsor
- NFL Biosciences SAS
Smoking, Nicotine Addiction
The END Perioperative Smoking Pilot Study
The purpose of this pilot randomized trial is to determine the feasibility of e-cigarettes and telephone counselling (compared to transdermal nicotine replacement and telephone counselling) as a harm-reduction tool that may lead…
- Conditions
- Smoking, Nicotine Addiction, Surgery
- Trial name
- NCT02482233
- Testing
- ENDD (NJOY), NRT (NicoDerm CQ), telephone counseling
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Francisco
Tobacco Use, Nicotine Pouch Self-Administration
Comparison of Demand and Substitution for Nicotine Pouches as a Function of Nicotine Dosage
Smoking is a prominent public health issue. Traditional nicotine replacement therapy suffers from being a poor substitute for cigarettes.
- Trial name
- NCT07213947
- Testing
- Nicotine Pouch Dosage
- Where
- United States
- Volunteers
- 1,360 people
- Sponsor
- William Middleton
Schizophrenia, Cigarette Smoking
Mobile Health Technology to Enhance Abstinence in Smokers With Schizophrenia
This study is designed to evaluate if a treatment the investigators call iCOMMIT is effective at helping smokers with schizophrenia stop smoking.
- Trial name
- NCT02420015
- Testing
- Nicotine replacement therapy, Bupropion, cognitive-behavioral smoking cessation counseling
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Duke University
Tobacco Dependence
Effects of Yoga and Cardiovascular Exercise on Smoking Motivation
The overall purpose of this pilot study is to examine effects of Hatha yoga and cardiovascular exercise on craving, mood, cue reactivity, and smoking behavior.
- Trial name
- NCT01423578
- Testing
- Hatha Yoga (HY), Cardiovascular Exercise (CE), Smoking Cessation Counseling
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
HIV Infections, AIDS
HIV Infection and Tobacco Use Among Injection Drug Users in Baltimore, Maryland: A Pilot Study of Biomarkers
Background: The incidence of lung cancer is quite high among people with the human immunodeficiency (HIV) virus. Frequent smoking may explain that cancer increase, given that 50% to 70% of HIV-infected people are current smokers.
- Conditions
- HIV Infections, AIDS, Lung Cancer, Tobacco Addiction
- Trial name
- NCT00491335
- Where
- United States
- Sponsor
- National Cancer Institute (NCI)
Smoking, Smoking Behaviors
Effects of E-cigs vs Pouches on Cigarette Smoking and Addiction
The study will recruit an anticipated 256 adults who currently smoke cigarettes and report a willingness to try switching to alternative, non-combustible products.
- Conditions
- Smoking, Smoking Behaviors, Nicotine Dependence
- Trial name
- NCT06077240
- Testing
- E-cigarette with 2.4% Nicotine with Menthol and Tobacco Flavors, E-cigarette with 2.4% Nicotine with Tobacco Flavor Only, E-cigarette with 5% Nicotine with Menthol and Tobacco Flavors
- Where
- United States
- Volunteers
- 256 people
- Sponsor
- Yale University
Nicotine Addiction
tDCS Effects on Resisting Smoking: Dose Ranging Study
Behaviors such as tobacco use, unhealthy diet, and sedentary behavior have far-reaching health implications. These modifiable behaviors account for a substantial proportion of deaths from cancer, cardiovascular disease and…
- Trial name
- RDR (NCT02624284)
- Testing
- transcranial direct current stimulation (tDCS)
- Where
- United States
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Tobacco Use
A Study to Evaluate Changes in Smokers Using Oral Tobacco-derived Nicotine Products.
The purpose of this study is to evaluate changes in exposure to selected harmful and potentially harmful constituents (HPHC) by measuring biomarkers in adult smokers who partially or completely switch from smoking cigarettes to…
- Trial name
- NCT03692078
- Testing
- OTDN product 1, OTDN product 2, Tobacco Cessation
- Where
- 2 sites in United States
- Volunteers
- 231 people, healthy volunteers welcome
- Sponsor
- Altria Client Services LLC
Obesity, Tobacco Smoking
Study of Bronchial Inflammation in Adolescent Smokers With and Without Obesity
The investigators want to assess differences in lung function and bronchial inflammation of young smokers and non-smokers with (BMI > 30) and without obesity (BMI < 25)(4 patient groups).
- Trial name
- NCT00942019
- Where
- Germany
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Johann Wolfgang Goethe University Hospital
Tobacco Use, Periodontitis
Snuff Use, Smoking, Periodontal Health and Premature Death: 30-year Study
Snuff use and smoking associated with poor periodontal health, especially if used together.
- Trial name
- NCT03614871
- Testing
- Epidemiological study
- Volunteers
- 1,676 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
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