Clinical trials: Tobacco Consumption
Lung Cancer
Lung Cancer Screening in a Population Exposed to Occupational Lung Carcinogens
The good clinical practice guidelines for the surveillance of workers after occupational exposure to lung carcinogens were approved by the Haute Autorité de la Santé (French National Authority for Health) and the Institut…
- Trial name
- LUCSO (NCT03562052)
- Where
- 8 sites in France
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Cocaine Dependence, Nicotine Dependence
Progesterone and Atomoxetine for Cocaine Cessation
The purpose of this study is to examine the role of progesterone (a hormone found in both men and women) on stopping cocaine use.
- Trial name
- NCT01741376
- Testing
- Progesterone
- Where
- United States
- Sponsor
- University of Minnesota
Tobacco Use Disorder, Repetitive Transcranial Magnetic Stimulation
fMRI Study of the Neural Mechanism of rTMS in the Treatment of Nicotine Dependence
The goal of this clinical trial is to investigate the efficacy of treatment and the efficacy-related neural network mechanisms by stimulating the left dorsolateral prefrontal lobe with rTMS to nicotine dependent.
- Trial name
- NCT06762535
- Testing
- repetitive transcranial magnetic stimulation
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tang-Du Hospital
Tobacco Use Cessation
Feasibility of a Culturally-Specific Video Text Cessation Intervention With AA Quitline Callers
Assess the feasibility and acceptability of delivering an mHealth tobacco intervention among state quitline enrollees.
- Trial name
- NCT03927976
- Testing
- Path2Quit - culturally specific text message intervention
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Case Comprehensive Cancer Center
Tobacco Dependence
Improving Health for Aboriginal People Through Tobacco Related Research
Aim: To identify barriers and facilitators in the uptake of smoking cessation pharmacotherapies, tobacco prevention, doctor visits, smoking amongst youth, community held health priorities and barriers to research in Aboriginal…
- Trial name
- NCT01735448
- Testing
- Focus group, One-on-one interviews, Survey
- Where
- 3 sites in Australia
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- The Queen Elizabeth Hospital
Healthy Subject, Tobacco Use Disorder
Effect of Black Raspberry Phytochemicals on Oral Microbiome in Current Smokers and Non-smokers
This randomized clinical trial studies the effects of black raspberry compounds (phytochemicals) on the bacteria in the mouth (oral microbiome) of current smokers and non-smokers.
- Trial name
- NCT02439255
- Testing
- Laboratory Biomarker Analysis, Phytochemical, Screening Questionnaire Administration
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
E-cigarette Use, Cigarette Smoking
BIDI Stick ENDS Abuse Liability and Puffing Topography Assessment
This study assessed the abuse liability (measured by assessing how much nicotine enters the body when the BIDI Stick is used, and how this makes users feel) and puffing topography (puff characteristics like volume and duration)…
- Trial name
- NCT05072925
- Testing
- Tobacco products
- Where
- Poland
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- BIDI Vapor
Tobacco Use
Shrinking the Size of the Tobacco Power Wall
The overall aim of this research is to experimentally evaluate the extent to which reducing the size of the tobacco power wall and the number of tobacco product units displayed influences tobacco use risk in adolescents.
- Trial name
- NCT04632030
- Testing
- Tobacco power wall size and tobacco products displayed
- Where
- United States
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- RAND
Smoking Cessation; Tobacco Dependence
Evaluation of the Effectiveness of a Very Brief Smoking Cessation Intervention in Family Health Centers
In Turkey, the prevalence of tobacco use among individuals was 31.4% in 2019. The WHO recommends brief and very brief interventions to increase tobacco cessation rates and medical support.
- Trial name
- NCT07030387
- Testing
- Smoking cessation counselling group, Control group patients were those who had not received the 3A-OR intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 330 people
- Sponsor
- Aydin Adnan Menderes University
Cigarette Smoker, Tobacco Use Disorder
Varenicline and Combined NRT for Smoking Cessation
This randomized pilot phase IV trial studies the side effects and how well varenicline works compared to nicotine replacement therapy in helping patients that smoke to quit.
- Trial name
- NCT02271919
- Testing
- Nicotine Lozenge, Nicotine Patch, Tobacco Cessation Counseling
- Where
- United States
- Volunteers
- 631 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Eye Manifestations, Tobacco; Use, Harmful
Effect of Smokeless Tobacco on Anterior Segment
Observational, comparative, cross-sectional study
- Conditions
- Eye Manifestations, Tobacco; Use, Harmful, Tobacco Chewing Toxicity
- Trial name
- NCT04776863
- Testing
- optical biometry measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 107 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Tobacco Use Disorder, Smoking
A Pilot Study to Evaluate the Efficacy of Ariva® Silver Wintergreen, a Smoking Aversive Lozenge
This is a study to determine the safety and effectiveness of silver salt in Ariva® Silver Wintergreen Lozenge on discouraging smoking, by its imparting an unfavorable taste to the smoker when tobacco is smoked.
- Trial name
- NCT01336816
- Testing
- Ariva Silver Wintergreen
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Star Scientific, Inc
Nicotine Dependence
Nicotine Differences in Smokers
The primary aim of this project is to determine the threshold dose of nicotine, which the smokers will be able to differentiate from placebo (saline).
- Trial name
- NCT05159934
- Testing
- 0.05, 0.025, and 0.0125 mg nicotine/pulse of nicotine, Saline
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Yale University
Tobacco Cessation
A Stepped Care Approach to Treating Tobacco Use in Rural Veterans
Tobacco use remains prevalent among Veterans. Although effective smoking cessation interventions exist, long-term term quit rates remain sub-optimal.
- Trial name
- Stepped Care (NCT04501016)
- Testing
- Tailored behavioral counseling, Tobacco cessation pharmacotherapy
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Iowa City Veterans Affairs Medical Center
Nicotine Dependence
Text Messaging to Engage and Retain Veterans in Smoking Cessation Counseling
Tobacco-related diseases account for a significant portion of all VA healthcare costs and are a detriment to the health and quality of life of our Veterans.
- Trial name
- TiMES (NCT03177265)
- Testing
- Text messaging prior to first counseling call, Text-to-Enhance, Mail Notice
- Where
- 2 sites in United States
- Volunteers
- 432 people
- Sponsor
- VA Office of Research and Development
Tobacco Use Disorder
Nicotine Regulation for Dual Users of E-cigarettes and Cigarettes
Cigarette smoking remains the leading cause of preventable morbidity and mortality in the US. Use of multiple tobacco products is becoming increasingly prevalent, with dual use of e-cigarettes and cigarettes representing the most…
- Trial name
- RDEC (NCT06614504)
- Testing
- Varying the nicotine content of cigarettes, Varying the nicotine content of e-cigarettes
- Where
- 2 sites in United States
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Tobacco Use
Remote Trial - Tobacco Product Standard (VLNC)
The goal of this pilot project is to explore the feasibility of a real-world marketplace study design examining the effects of a reduced nicotine product standard for cigarettes on smoking in the context of a flavor restriction…
- Trial name
- NCT06442384
- Testing
- Tobacco and non-tobacco e-cigarettes, Tobacco only e-cigarettes
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Masonic Cancer Center, University of Minnesota
Insomnia, Nicotine Dependence
Study of Lunesta Versus Placebo for Sleep Problems Related to Smoking Cessation and Zyban
Objectives: The primary objective of this study is to determine the efficacy of eszopiclone at treating sleep problems related to withdrawal from nicotine in healthy smokers attempting smoking cessation.
- Trial name
- NCT00511134
- Testing
- Eszopiclone, Bupropion
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Yale University
Nicotine Dependence
Effects of Menthol in E-cigarettes on Smoking Behaviors
The overall goal of this proposal is to understand the relationship between nicotine metabolism and menthol flavor in e-cigarettes on smoking behavior in smokers.
- Trial name
- NCT04521647
- Testing
- Nicotine
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Yale University
Myocardial Infarction (MI), Tobacco Use
Telegram Messenger Support for Smoking Cessation After Heart Attack
This randomized controlled trial will evaluate whether a 6-month behavioral intervention delivered via Telegram messenger increases smoking cessation rates in patients after myocardial infarction (MI).
- Conditions
- Myocardial Infarction (MI), Tobacco Use, Smoking Cessation
- Trial name
- TELEGRAM-MI (NCT07230249)
- Testing
- Telegram-based Smoking Cessation Support, Standard Care (in control arm)
- Where
- Russia
- Volunteers
- 142 people
- Sponsor
- ITMO University
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