Clinical trials: Tobacco Consumption
Asthma, Incentives
Financial Incentives to Reduce Pediatric Tobacco Smoke Exposures
Secondhand smoke exposure (SHSe) is one of the most common and potentially modifiable environmental triggers for asthma. Financial incentivization may serve as an effective modality to reduce SHSe among pediatric asthmatics with…
- Conditions
- Asthma, Incentives, Tobacco Smoking
- Trial name
- NCT03099811
- Testing
- Incentive plan, Smoking cessation
- Where
- United States
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Smoking Cessation; Tobacco Dependence
Evaluation of the Effectiveness of a Very Brief Smoking Cessation Intervention in Family Health Centers
In Turkey, the prevalence of tobacco use among individuals was 31.4% in 2019. The WHO recommends brief and very brief interventions to increase tobacco cessation rates and medical support.
- Trial name
- NCT07030387
- Testing
- Smoking cessation counselling group, Control group patients were those who had not received the 3A-OR intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 330 people
- Sponsor
- Aydin Adnan Menderes University
Tobacco Use Cessation
Improving Varenicline Adherence and Outcomes in Homeless Smokers
the purpose of the study is to see if varenicline in combination with motivational counseling helps homeless cigarette smokers quit smoking.
- Trial name
- NCT00786149
- Testing
- Varenicline plus Motivational Interviewing counseling, Varenicline without counseling
- Where
- United States
- Volunteers
- 428 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Bronchial Dysplasia, Tobacco Smoking
Nivolumab for the Reversal of Squamous Dysplasia in High Risk Current and Former Smokers
The goal of this clinical research study is to determine whether the PD-1 inhibitor (Programmed cell death protein 1) nivolumab improves premalignant bronchial dysplastic lesions in subjects that are at high risk for the…
- Conditions
- Bronchial Dysplasia, Tobacco Smoking, History of Non-Small Cell Lung Cancer, History of Head and Neck Cancer
- Trial name
- NCT03347838
- Testing
- Nivolumab
- Where
- 2 sites in United States
- Volunteers
- 19 people
- Sponsor
- University of Colorado, Denver
Cigarette Smoking Behavior
Enhancing Source Credibility in Tobacco Regulatory Communications
This study will assess the impact of cigarette constituent messages with and without FDA source and quit information in a randomized controlled trial.
- Trial name
- NCT03339206
- Testing
- Constituent message with FDA and quitline, Constituent message without FDA and quitline, Littering message (Control)
- Where
- United States
- Volunteers
- 845 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Smoking Cessation
Meclizine as a Potential Smoking Cessation Treatment
The purpose of this study is to evaluate whether meclizine, an antihistamine used to prevent or treat motion sickness, can help smokers quit smoking.
- Trial name
- NCT01443858
- Testing
- Meclizine, Nicotine Patch
- Where
- 4 sites in United States
- Volunteers
- 146 people
- Sponsor
- Duke University
Adverse Childhood Experiences, Nicotine Dependence, Cigarettes
Neurobehavioral Mechanisms Linking Childhood Adversity to Increased Risk for Smoking
The purpose of this study is to evaluate how certain childhood experiences influences brain function and responses to nicotine exposure in a group of nonsmoking young adults.
- Trial name
- NCT05665465
- Testing
- Nicotine nasal spray 0.5 mg
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Duke University
Cardiovascular Risk Factor, Nicotine Dependence
Vaping High vs. Low Nicotine E-Liquid
This study will examine the effects of electronic cigarette e-liquid nicotine content in a randomized, crossover clinical and behavioral pharmacology study of experienced adult e-cigarette users (N=36).
- Trial name
- NCT04047836
- Testing
- Low Nicotine E-Liquid, Medium or High Nicotine E-Liquid
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Tobacco Dependence
Multiple-dose Nicotine Pharmacokinetics With a New Oral Nicotine Replacement Product.
A comparison of three products for oral nicotine replacement with respect to pharmacokinetics after multiple-doses of nicotine.
- Trial name
- NCT01084707
- Testing
- Oral Nicotine, Nicotine Lozenge, Nicotine gum
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- McNeil AB
Smoking, Smoking Behaviors
A Study to Assess Nicotine Uptake From Electronic Nicotine Delivery Systems
This will be an open-label, randomized, single-site, 8-way crossover study designed to evaluate plasma nicotine pharmacokinetic (PK) parameters and overall product liking (OPL) following an ad libitum use of Electronic Nicotine…
- Conditions
- Smoking, Smoking Behaviors, Tobacco Use, Tobacco Smoking
- Trial name
- NCT07323563
- Testing
- Product A, Product B, Product C
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- RAI Services Company
Nicotine Dependence
Coping Skills Treatment for Smoking Cessation
The primary purpose of this study is to evaluate the efficacy of a new type of exposure- and acceptance-based smoking cessation treatment vs.
- Trial name
- Project-WIN (NCT01061528)
- Testing
- Transdermal Nicotine
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Butler Hospital
Tobacco Use Cessation
Project Q Pilot: Smoking Cessation for Light Smokers
The purpose of this pilot study is to evaluate the feasibility, acceptability, and preliminary efficacy of an intervention to promote smoking cessation among light smokers.
- Trial name
- NCT03416621
- Testing
- Cognitive behavioral cessation counseling, Counseling and active drug intervention
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Duke University
Cigarette Smoking
iQuit Mindfully: Text Messaging for Smoking Cessation
The purpose of this study is to investigate text messaging as a way to enhance mindfulness-based treatment for smoking cessation.
- Trial name
- NCT03029819
- Testing
- Mindfulness-based Addiction Treatment, iQuit Mindfully, Self-Help guide
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Georgia State University
Electronic Cigarette Use, Cigarette Smoking
Effects of e-Cigarettes on Perceptions and Behavior - Remote Substudy # 2
This study assess the ways in which e-cigarette product characteristics, such as flavors and nicotine salts, impact user experience to inform potential regulations.
- Conditions
- Electronic Cigarette Use, Cigarette Smoking, Cigarette Use, Electronic, Vaping
- Trial name
- NCT05958992
- Testing
- E-cigarette
- Where
- United States
- Volunteers
- 461 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Tobacco Use Disorder
The Effects of Sedatives on Tobacco Use Disorder
This proposal will obtain preliminary data on the effect of a single sub-anesthetic dose of a sedative on cigarette craving and smoking behavior as well as measuring tolerability and acceptability.
- Trial name
- SED-TUD (NCT03813121)
- Testing
- midazolam intravenous infusion, ketamine intravenous infusion
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Tobacco Use Disorder
Nicotine Regulation for Dual Users of E-cigarettes and Cigarettes
Cigarette smoking remains the leading cause of preventable morbidity and mortality in the US. Use of multiple tobacco products is becoming increasingly prevalent, with dual use of e-cigarettes and cigarettes representing the most…
- Trial name
- RDEC (NCT06614504)
- Testing
- Varying the nicotine content of cigarettes, Varying the nicotine content of e-cigarettes
- Where
- 2 sites in United States
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Cigarette Smoking, Alcohol Use Disorders
Varenicline + Prazosin for Heavy Drinking Smokers
The purpose of this study is to examine the effect of varenicline and prazosin on smoking, drinking, and sleep among cigarette smokers who report heavy alcohol use. Varenicline is an FDA approved smoking cessation medication.
- Trial name
- NCT02193256
- Testing
- Varenicline, Prazosin
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Yale University
Nicotine Dependence, Nicotine Withdrawal
Progesterone and Brain Imaging Study
Male and female smokers were recruited to undergo 2 phases of smoking cessation. Each phase was 4 days long and involved 3 brain-imaging scans, blood draws and an intervention involving progesterone or a matched placebo.
- Trial name
- NCT01954966
- Testing
- Progesterone
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Nicotine Dependence
Varenicline (Chantix) Treatment for Waterpipe Smoking Cessation
The lack of proven waterpipe smoking cessation interventions makes it important to explore interventions proven effective for cigarette smoking cessation.
- Trial name
- NCT02575183
- Testing
- Varinecline (Chantix), Behavioral Therapy
- Where
- 2 sites in Lebanon
- Volunteers
- 152 people
- Sponsor
- American University of Beirut Medical Center
Tobacco Use Cessation, Tobacco Smoking
Development of a Smoking Cessation Video Series
This study seeks to develop and test an internet video series aimed at helping individuals reduce cigarette smoking. Participants (daily smokers) will be asked to watch a series of six videos (approximately 6.5 minutes each)…
- Trial name
- NCT06443294
- Testing
- Smoking cessation video series.
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Wayne State University
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