Clinical trials: Tobacco Consumption
Tobacco Use Disorder
An fMRI Study of the Effects of Clavulanic Acid on Drug Addiction
This research study is looking into the effects of clavulanic on smoking behavior in adult cigarette smokers. The primary study hypothesis is that, compared to placebo, clavulanic acid will reduce smoking over the course of the…
- Trial name
- NCT03713424
- Testing
- Clavulanic Acid
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Alcohol-induced Disorders, Drug Users
SBIRT Implementation for Adolescents in Urban Federally Qualified Health Centers
The purpose of this study is to examine the implementation of two evidence-based intervention strategies of SBIRT (Generalist vs. Specialist) for adolescent alcohol, tobacco, other drug use, and HIV risk behaviors.
- Conditions
- Alcohol-induced Disorders, Drug Users, Tobacco Use Disorder
- Trial name
- ST@T (NCT01829308)
- Testing
- The brief interventions are delivered by behavioral health counselors (Specialist), The brief interventions are delivered by the primary care provider (Generalist)
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Friends Research Institute, Inc.
Smoking Behaviors, Smoking, Non-Tobacco Products
Tobacco/Nicotine Purchase Patterns Across SES
In a within-subject design, investigators will use the Experimental Tobacco Marketplace (ETM) to systematically impose 4 novel tobacco/nicotine tax proposals (Tobacco Parity, Nicotine-Content, Harm-Reduction, and Modified Risk…
- Conditions
- Smoking Behaviors, Smoking, Non-Tobacco Products, Smoking, Cigarette
- Trial name
- AIM2 (NCT06795997)
- Testing
- Tax Conditions, Control Condition
- Where
- United States
- Volunteers
- 663 people, healthy volunteers welcome
- Sponsor
- Virginia Polytechnic Institute and State University
Tobacco Smoking, Pregnancy
Family Smoking Cessation in Romania Using Pregnancy as a Window of Opportunity
The purpose of this research is to adapt and implement a pregnancy and postnatal smoking cessation intervention for couple that will begin early in pregnancy and have an additional postnatal component.
- Trial name
- QuitTogether (NCT02512913)
- Testing
- Adapted/enhanced MAPS
- Where
- Romania
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Lung Cancer, Tobacco Use Disorder
Biomarkers for Early Detection of Lung Cancer in Patients With Lung Cancer, Participants at High-Risk for Developing Lung Cancer, or Healthy Volunteers
RATIONALE: Collecting and storing samples of sputum and tissue to study in the laboratory may help doctors identify biomarkers related to cancer.
- Trial name
- NCT00899262
- Testing
- immunohistochemistry staining method, laboratory biomarker analysis, sputum cytology
- Where
- 2 sites in United Kingdom
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- South West Wales Cancer Institute
Smoking, Smoking Cessation
Evaluation of Treatments to Improve Smoking Cessation Medication Adherence
Many smokers fail to take their smoking cessation medication as recommended. This research is designed to identify treatments that improve the use of cessation medications and to determine whether an increase in medication use…
- Conditions
- Smoking, Smoking Cessation, Adherence, Nicotine Dependence
- Trial name
- Adherence (NCT01120704)
- Testing
- Short Term Combination Nicotine Replacement Therapy (patch + gum), Long Term Combination Nicotine Replacement Therapy (patch + gum), Intensive Maintenance Counseling
- Where
- United States
- Volunteers
- 544 people
- Sponsor
- University of Wisconsin, Madison
Cigarette Smoking, E-cigarette Use
Effects of a Low Nicotine Standard and Tobacco Prices on Illegal Cigarette Purchasing
This study will investigate the effects of a very-low-nicotine cigarette (VLNC) standard, e-cigarette price, and illegal cigarette price on illegal product purchasing and alternative product use in a virtual marketplace.
- Trial name
- NCT07161050
- Testing
- Nicotine Content, Illegal cigarette price, E-cigarette price
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Virginia Polytechnic Institute and State University
Cigarette Addiction, Tobacco Use Disorder
Impact of Novel vs. Usual Brand Menthol Cigarettes on Abuse Liability
This randomized, double-blind, crossover human laboratory study compares the abuse liability of cigarettes containing menthol and non-menthol cigarette variants, using the participant's usual brand menthol cigarette as a…
- Trial name
- NCT07564648
- Testing
- Biospecimen Collection, Questionnaire Administration, Cigarette Purchase Task
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Tobacco Cessation, Dental Practice
To Promote Tobacco Free Life in the Dental Practice in France
In France, 34% of the adult population is smoking every day. The links between smoking and the development of several chronic disorders is well established and smoking is directly implicated in most of the oral diseases such as…
- Trial name
- TOBAFREE-DP (NCT04498858)
- Testing
- Patient interview
- Where
- France
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Smoking, Tobacco Use
CSD190301: A Study to Assess Elements of Abuse Liability for Two Dissolvable Nicotine Lozenge Tobacco Products
This is a two-arm, single use, single-center, randomized, 10-sequence per arm, open-label, crossover pharmacokinetic/pharmacodynamic (PK/PD) study, designed to evaluate elements of abuse liability (AL) including subjective…
- Conditions
- Smoking, Tobacco Use, Tobacco Smoking
- Trial name
- NCT04167384
- Testing
- Product A, Product B, Product C
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- RAI Services Company
Smoking, Tobacco Use
CSD201202: A Study to Assess Nicotine Uptake From Electronic Nicotine Delivery System P12
This is an open-label, randomized, 8-way crossover study designed to evaluate plasma nicotine pharmacokinetic (PK) parameters following an ad libitum use of Electronic Nicotine Delivery System (ENDS) investigational products…
- Trial name
- NCT05239884
- Testing
- ENDS Product A with 1.5% nicotine, ENDS Product B with 1.5% nicotine, ENDS Product C with 1.5% nicotine
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- RAI Services Company
Smoking Cessation
Countering Young Adult Tobacco Marketing in Bars
The goal of the study is to implement and evaluate interventions to decrease smoking among young adults attending bars and nightclubs.
- Trial name
- NCT01686178
- Testing
- Anti-smoking social marketing campaign
- Where
- United States
- Volunteers
- 17,422 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Tobacco Use Disorder
Effect of Banning Menthol Flavorant on Cigarette and E-Cigarette Use
In this pilot study, menthol cigarette smokers will be randomized to one of three experimental marketplaces: 1) a condition simulating a ban on menthol cigarettes but not menthol e-cigarettes (condition A); 2) a condition…
- Trial name
- NCT03402243
- Testing
- Menthol ban on cigarettes, Menthol ban on cigarettes and e-cigarettes, No menthol ban
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Cigar Smoking, Tobacco Use
Cigar Legislation and Regulation in Tobacco for the Young (Project CLARITY)
This clinical trial will recruit young adults who currently use cigarillos and examine the smoking behavior and perceptions of different flavored cigarillos, product ingredients/additives impacting these perceptions, and…
- Trial name
- CLARITY (NCT07162935)
- Testing
- Cigarillo brand 1, Cigarillo brand 2, Cigarillo brand 3
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Smoking Cessation, Pulmonary Disease, Chronic Obstructive
Impact of Primary Care COPD Screening Strategies on the Smoking Cessation Process (DISCO-SET)
The general practitioner is confronted with unselected smokers whose attempts to quit smoking are often repeated over time before leading to a definitive cessation.
- Trial name
- DISCO-SET (NCT04833933)
- Testing
- Phone survey about smoking cessation process since intervention in DISCO trial
- Where
- 12 sites in France
- Volunteers
- 120 people
- Sponsor
- Rennes University Hospital
Smoking Cessation, Tobacco Use Cessation
Financial Incentives for Smoking Treatment II
Financial incentives for motivating changes in health behavior, particularly for smoking and other morbid habits, are increasingly being tested by health insurers, employers, and government agencies.
- Trial name
- FIESTA II (NCT03979885)
- Testing
- Smoking cessation counseling (Quitline), Smoking cessation pharmacotherapy (e.g, nicotine replacement therapy), Financial incentives for smoking cessation
- Where
- 2 sites in United States
- Volunteers
- 1,058 people
- Sponsor
- University of California, Los Angeles
Healthy Smokers
Nicotine Patch - Bioequivalence Study
The purpose of this study is to evaluate the bioequivalence of a new transdermal nicotine patch to that of a reference formulation following repeated applications
- Trial name
- NCT02089308
- Testing
- Test treatment : V0116 transdermal patch, Reference treatment : Nicotine transdermal patch
- Where
- France
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Pierre Fabre Medicament
Nicotine Dependence
TMS-fMRI for Neural Pathway in Smokers
Cigarette smoking causes significant morbidity and mortality in the United States. Smoking cessation is difficult, with the average smoker attempting to quit five times before permanent success.
- Trial name
- NCT02665338
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Xingbao Li
E-cigarette Use, Cigarette Smoking
Noncombustible Nicotine Delivery Systems as Potential Harm Reduction Tools for Persistent Cigarette Smokers
This between-subjects study aims to evaluate whether e-cigarettes (ECIGS) versus oral nicotine pouches (ONPS) more readily substitute for combustible cigarettes among 200 cigarette smokers.
- Conditions
- E-cigarette Use, Cigarette Smoking, Harm Reduction, Tobacco Use
- Trial name
- NCT06372899
- Testing
- E-cigarettes, Oral nicotine pouches
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Abramson Cancer Center at Penn Medicine
Lung Cancer, Tobacco Use Disorder
Green Tea Extract in Preventing Cancer in Former and Current Heavy Smokers With Abnormal Sputum
RATIONALE: Chemoprevention is the use of certain drugs to keep cancer from forming. Green tea extract may keep cancer from forming.
- Trial name
- NCT00573885
- Testing
- defined green tea catechin extract
- Where
- Canada
- Volunteers
- 53 people
- Sponsor
- British Columbia Cancer Agency
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