Clinical trials: Tobacco Consumption
Tobacco Use Disorder, Homelessness
Abstinence Reinforcement Therapy (ART) for Homeless Veteran Smokers
The goal of this research study is to examine the effects of a treatment for helping homeless veterans who smoke to stop smoking. Participants in the study will be assigned to one of two study groups.
- Trial name
- NCT02245308
- Testing
- Nicotine Patches, mobile contingency management (mCM), Smoking cessation counseling
- Where
- United States
- Volunteers
- 133 people
- Sponsor
- VA Office of Research and Development
Tobacco Use Cessation
Quit and Win Contests to Improve Smoking Cessation Among College Students
Standard Quit and Win contests, in which smokers typically quit for one month in return for the opportunity to win prizes, are simple and easy to implement and may be cost-effective in encouraging smokers to quit.
- Trial name
- NCT01096108
- Testing
- Standard contest (1 month), Motivational and Problem-Solving, Extended Contests
- Where
- United States
- Volunteers
- 1,318 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Smoking ( Cigarette)
Impact of Sweeteners on the Addictive Threshold of Nicotine
To determine if sucralose, an artificial sweetener, modulates nicotine threshold doses for discrimination, subjective-rewarding effects, and reinforcement in smokers with varying levels of dependence.
- Trial name
- NCT07771725
- Testing
- Nicotine 0.05 mg/pulse and 0.1 mg/pulse, sucralose
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Yale University
Smoking Cessation
Evaluation of an Intensive Education Program on the Treatment of Tobacco Use Disorder for Pharmacists: a Randomized Controlled Trial
In Qatar, tobacco use is one of the main causes of premature deaths and preventable diseases. As per the 2013 Global Adult Tobacco Survey (GATS), 12.1% of adults and 20.2% of men in Qatar smoke tobacco, and 55.4% of this smoke an…
- Trial name
- NCT03518476
- Testing
- intensive multi-disciplinary education program on tobacco treatment for pharmacists, Control arm
- Where
- Qatar
- Volunteers
- 164 people
- Sponsor
- Qatar University
Nicotine Dependence, E-cigarette Use
Sex Differences in E-Cigarette Perception
This study examines differences between males and females in the appeal and addiction potential of menthol flavored e-cigarettes with and without nicotine.
- Trial name
- NCT07398976
- Testing
- Nicotine Level 1 (0mg/ml), Nicotine Level 2 (36mg/ml), Nicotine Level 3 (59mg/ml)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yale University
Tobacco Smoking
Pragmatic Randomised Controlled Trial Evaluating Effectiveness of a Smoking Cessation e- Intervention " Tabac Info Service "
Introduction - A national smoking cessation E-intervention, called Tabac Info Service (TIS), was developed in France to provide an adapted web and mobile application support to smoking cessation for all adults smokers, with or…
- Trial name
- NCT02841683
- Testing
- Tabac Info Service
- Where
- France
- Volunteers
- 2,806 people
- Sponsor
- Ecole des Hautes Etudes en Santé Publique
Tobacco Use, Tobacco Use Disorder
QuitGuide for American Indians: Aims 2 & 3
Aim 3: To test feasibility, acceptability, and preliminary efficacy of the tailored QuitGuide for smoking cessation among AIs.
- Trial name
- NCT05447156
- Testing
- Tailored QuitGuide app, Standard QuitGuide app
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Masonic Cancer Center, University of Minnesota
Nicotine Dependence
Study of Varenicline (Champix) for Smoking Cessation/Reduction in Patients With Bipolar Disorder
Bipolar Disorder is a chronic relapsing mental disorder characterized by periods of elevated, expansive and irritable mood, often alternating with periods of significant clinical depression.
- Trial name
- NCT01093937
- Testing
- varenicline
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Centre for Addiction and Mental Health
Nicotine Dependence
GABA (Gamma Amino Butyric Acid) Medication for Tobacco
The goal of this study is to examine the effects of a GABA (gamma amino butyric acid)-enhancing medication, pregabalin (300 mg/day), on smoking behavior, tobacco withdrawal and cigarette craving in smokers.
- Trial name
- NCT00644137
- Testing
- pregabalin, cigarettes
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Yale University
Tobacco Smoking
Potential Impact of Menthol Ban in Cigarettes and E-cigarettes
Menthol cigarette use remains a major public health problem and the FDA has proposed to ban menthol in cigarettes. However, additional evidence is needed to understand whether menthol flavor in e-cigarettes is important for harm…
- Trial name
- NCT05259566
- Testing
- menthol ban in cigarettes only, total menthol ban
- Where
- United States
- Volunteers
- 151 people
- Sponsor
- Yale University
Tobacco Use Disorder
Smoking Cessation Treatment for Substance Use Dependents
The present research project aims to develop an innovative and empirically validated intervention protocol for smoking cessation among patients with substance use disorders (SUDs).
- Trial name
- NCT03551704
- Testing
- CBT + EFT, CBT + EFT + CM
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- University of Oviedo
Tobacco Smoking
Methods Project 4: Clinical Trial - Amended
Cigarette smokers will be randomized to E-cigarette, Nicotine Gum or Lozenge, or Control Group. Participants will enter a 1 week sampling phase.
- Trial name
- COMET (NCT03111537)
- Testing
- Cigarettes, E-Cigarette, Nicotine Gum or Lozenge
- Where
- 3 sites in United States
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Nicotine Dependence
E-cigarettes and Blood Vessel Function
Randomized controlled trial of electronic cigarettes with nicotine, without nicotine, and sham control, on endothelial function and markers of oxidative stress.
- Trial name
- NCT02740595
- Testing
- one time exposure to e-cig with nicotine, one time exposure to e-cig without nicotine, one time exposure to empty e-cig
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Pregnant Woman Who Uses Tobacco
Assessement of a Test a Financial-incentive Program for Pregnant Women and Their Smoking Partners to Reduce Smoking During Pregnancy.
Nearly one in five pregnant women still smoke in the third trimester of pregnancy. This is the highest rate in Europe. Smoking during pregnancy is an established risk factor for the unborn child: risk of ectopic pregnancy…
- Trial name
- PREVENT (NCT07528664)
- Testing
- Financial incentive contingent on tobacco abstinence., Standar care
- Where
- France
- Volunteers
- 180 people
- Sponsor
- University Hospital, Lille
Smoking Behaviors, Cigarette Smoking
Impact of Nicotine Messaging on Beliefs and Behavior
The purpose of this study is to examine the effect of nicotine messaging and nicotine content of study cigarettes on nicotine beliefs and subsequent use of tobacco and nicotine products.
- Trial name
- NCT05108649
- Testing
- Nicotine Messaging, Cigarette Condition
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Andrew Strasser
Nicotine Dependence, Nicotine Withdrawal
Human Laboratory Study of Varenicline and Bupropion for Nicotine Dependence
The objective of this proposal is to elucidate effects of bupropion SR + varenicline on smoking-cessation related processes in early abstinence using a human laboratory model.
- Trial name
- ChanBan (NCT00749658)
- Testing
- Bupropion, Varenicline
- Where
- United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Bronchiolitis, Pneumonia
A Study of Tobacco Smoke and Children With Respiratory Illnesses
This study aims to assess the feasibility of using an intervention for environmental smoke exposure in children that uses cotinine testing results with written materials and telephone counseling for a potential future study of…
- Conditions
- Bronchiolitis, Pneumonia, Reactive Airway Disease, Asthma
- Trial name
- NCT03062709
- Testing
- Breathe Easy Coalition written materials, Maine Tobacco Helpline, Urine cotinine testing
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- MaineHealth
Infections Joint Prosthetic, Overweight or Obesity
Antibiotic Prophylaxis in High-Risk Arthroplasty Patients
To determine the effectiveness of a 7-day course of an oral, prophylactic antibiotic on the incidence of periprosthetic joint infection and wound complications following primary total hip and knee arthroplasty in a high-risk…
- Conditions
- Infections Joint Prosthetic, Overweight or Obesity, MSSA Colonization, MRSA
- Trial name
- NCT04297592
- Testing
- Cephalexin, Doxycycline, Cefadroxil
- Where
- 2 sites in United States
- Volunteers
- 4,618 people
- Sponsor
- Mayo Clinic
Alcohol; Harmful Use, Tobacco Use
Screening While You Wait 2: Alcohol and Tobacco Use
This project aims to help patients improve their health through screening and treatment of risky alcohol and tobacco use. Previous studies show the best approach to reduce substance use includes routine screening, short…
- Conditions
- Alcohol; Harmful Use, Tobacco Use, Tobacco Use Cessation, Alcohol Use, Unspecified
- Trial name
- SWYW2 (NCT04594304)
- Testing
- Behavioral: Usual care plus eToolkit
- Where
- Canada
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Women's College Hospital
Smoking Cessation, Tobacco Use Disorder
A Randomized Trial of Internet Access to Nicotine Patches
People who smoke cigarettes have an increased risk of developing emphysema, heart disease, and certain types of cancer. This study will evaluate the effectiveness of providing free nicotine patches from an online smoking…
- Trial name
- iQS (NCT00534404)
- Testing
- Nicotine patches, Telephone counseling, iQuit Smoking website
- Where
- United States
- Volunteers
- 2,485 people, healthy volunteers welcome
- Sponsor
- University of Michigan
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