Clinical trials: Tobacco Consumption
Tobacco Use Cessation
Optimizing the Tobacco Cessation Clinical Decision Support Tool.
The existing tobacco cessation best practice advisory (BPA) fires for providers (physicians, residents, fellows, midwives, nurse practitioners, physician assistants) during outpatient encounters when a patient is identified as a…
- Trial name
- NCT03714191
- Testing
- Patient Outcomes, Billing documentation, Regulatory
- Where
- United States
- Volunteers
- 54,417 people
- Sponsor
- NYU Langone Health
Smoking Cessation, Smoking, Cigarette
Randomized Trial of Electronic Cigarettes With or Without Nicotine in Smoking Cessation.
Background: Electronic cigarettes (EC) mainly containing nicotine (88-95 % of users) are widely and growingly used worldwide. It is estimated that there were 1.7 million daily users in France in 2016.
- Conditions
- Smoking Cessation, Smoking, Cigarette, Electronic Cigarette
- Trial name
- ECSMOKE (NCT03630614)
- Testing
- Electronic cigarette without nicotine (ECwN) plus active varenicline tablets
- Where
- France
- Volunteers
- 650 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Smoking ( Cigarette), Cornea
Acute Ocular Effects of Cigarette Smoking
This prospective study aims to evaluate the short-term effects of smoking on corneal tomographic and biometric measurements in healthy adults.
- Conditions
- Smoking ( Cigarette), Cornea, Anterior Eye Segment Measurements
- Trial name
- NCT07580040
- Testing
- Cigarette Smoking Exposure, No Smoking Exposure
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Smoking Cessation, Nicotine Dependence
Neuropsychological Prognosis Factors of Smoking Cessation
The low overall effectiveness of available smoking cessation treatment so far, indicate the need for new and more efficacious ways to help smokers maintain abstinence. Smokers are a highly heterogeneous population.
- Trial name
- NCT01554436
- Testing
- neuropsychological assessment
- Where
- France
- Volunteers
- 135 people
- Sponsor
- University Hospital, Montpellier
Smoking, Tobacco Use
BAT3221032: A Study to Evaluate the Effects of Switching From Cigarette Smoking to Using One of Five Variants of a Heated Tobacco Product on Biomarkers of Exposure and Biomarkers of Potential Harm in Healthy Subjects
This is a randomized, controlled, multi-center, open-label, 8-cohort parallel group study to assess changes in select biomarkers of exposure (BoE) and biomarkers of potential harm (BoPH) in generally healthy smokers switching to…
- Conditions
- Smoking, Tobacco Use, Tobacco Smoking
- Trial name
- NCT05142436
- Testing
- Product A: Non-Combusted Cigarette Variant 42001402 and product use Mode B, Product B: Non-Combusted Cigarette Variant 42001399 and product use Mode B, Product C: Non-Combusted Cigarette Variant 42001401 and product use Mode B
- Where
- 18 sites in United States
- Volunteers
- 806 people, healthy volunteers welcome
- Sponsor
- British American Tobacco (Investments) Limited
Tobacco Use Disorder
Nicotine Patch and Bupropion to Reduce Smoking Rates in Younger, Low-Income, and Minority Individuals
Nicotine addiction is a serious health problem in the United States; 46 million people smoke cigarettes, and 70% of those are trying to quit.
- Trial name
- NCT00308763
- Testing
- Nicotine Patch, Sustained Release Bupropion
- Where
- United States
- Volunteers
- 594 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Tobacco Smoking
Pilot Testing a Computer Delivered Tobacco Cessation Intervention in Outpatient Clinical Settings: A Feasibility Study
The investigators have developed a hybrid computer- and person-delivered intervention, called "C-Raven" for smoking cessation that is tailored to people with tobacco use in Baltimore City.
- Trial name
- NCT05145738
- Testing
- C-Raven with avatar, C-Raven without avatar
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Cigarette Smoking, Tobacco Smoking
Enhancing Smoking Cessation in the Homeless Population
The goal of this research study is to enhance smoking cessation rates for homeless smokers. The original study design proposed to test the effects of 1) an Intensive Smoking Intervention, and 2) integrating alcohol abuse…
- Conditions
- Cigarette Smoking, Tobacco Smoking, Smoking, Tobacco
- Trial name
- NCT01932996
- Testing
- nicotine patch plus nicotine gum/lozenge, Intensive Alcohol Intervention
- Where
- United States
- Volunteers
- 352 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Nicotine Dependence
Varenicline (Chantix) Treatment for Waterpipe Smoking Cessation
The lack of proven waterpipe smoking cessation interventions makes it important to explore interventions proven effective for cigarette smoking cessation.
- Trial name
- NCT02575183
- Testing
- Varinecline (Chantix), Behavioral Therapy
- Where
- 2 sites in Lebanon
- Volunteers
- 152 people
- Sponsor
- American University of Beirut Medical Center
Nicotine Dependence, Nicotine Addiction
A Smartphone Application (ACT on Vaping) for Vaping Cessation in Young Adults
Almost one in ten young adults report current e-cigarette use, putting them at risk of developing nicotine addiction and long-term health effects of exposure to inhaled toxicants.
- Conditions
- Nicotine Dependence, Nicotine Addiction, Nicotine Use Disorder, Nicotine Vaping
- Trial name
- NCT05897242
- Testing
- Smartphone app, Text Message, Survey Administration
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Tobacco Dependence, Schizophrenia
Cigarette Smoking in Smokers With and Without Schizophrenia
Higher rates and severity of tobacco dependence in people with schizophrenia, as compared with the general population, contribute to the lower life expectancy seen in this population.
- Trial name
- NCT04001114
- Testing
- Sampling Research Cigarettes
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Tobacco Use Cessation, Tobacco Use Disorder
Feasibility of a Medical-Legal Partnership Model to Connect Coal Miners QuitAid
Coal miners in Central Appalachia have among the highest rates of tobacco and nicotine product (TNP) use of any occupational group and face elevated rates of lung cancer and coal workers' pneumoconiosis ("black lung").
- Conditions
- Tobacco Use Cessation, Tobacco Use Disorder, Nicotine Dependence, Smokeless Tobacco Use
- Trial name
- NCT07694492
- Testing
- QuitAid (pharmacist-delivered MTM), Nicotine Replacement Therapy (NRT)
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Nicotine Dependence
Nicotine Differences in Smokers
The primary aim of this project is to determine the threshold dose of nicotine, which the smokers will be able to differentiate from placebo (saline).
- Trial name
- NCT05159934
- Testing
- 0.05, 0.025, and 0.0125 mg nicotine/pulse of nicotine, Saline
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Yale University
Tobacco Dependence
Targeted Pharmacological and Behavioral Treatments for Smoking in Schizophrenia Study 1
Schizophrenia is associated with high rates of cigarette smoking and associated morbidity and mortality. In this study, smokers with schizophrenia will complete a baseline session and then randomized to varenicline (VAR) or…
- Trial name
- NCT03507127
- Testing
- Varenicline
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Brown University
Mental Illness
Trial of Integrated Smoking Cessation, Exercise and Weight Management in Serious Mental Illness: TRIUMPH
This study will determine whether an 18-month practical tobacco smoking cessation program integrating weight management counseling and exercise will be superior to treatment as usual in achieving prolonged smoking abstinence in…
- Trial name
- TRIUMPH (NCT02424188)
- Testing
- TRIIUMPH Intervention
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- Johns Hopkins University
Cigarette Smoking, Smoking Cessation
Goal2Quit + NRT Sampling
The goal of this work is to develop, systematically evaluate, and clinically test an integrated cessation intervention comprised of a depression-specific Behavioral Activation (BA) for cessation mobile app ("Goal2Quit") packaged…
- Conditions
- Cigarette Smoking, Smoking Cessation, Depression
- Trial name
- NCT03837379
- Testing
- Treatment as Usual, Goal2Quit + NRT Sampling
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- Medical University of South Carolina
Tobacco Use
CSD190101: A Study to Assess Nicotine Pharmacokinetic Parameters After Use of Two Smokeless Tobacco Products
The purpose of this study is to compare plasma nicotine uptake in adult snus consumers after using investigational snus products (A19010-F and B19010-F).
- Trial name
- NCT03993769
- Testing
- A19010-F, B19010-F
- Where
- 6 sites in United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- RAI Services Company
Tobacco Cessation, Health Warning Label
Health Warnings and Counseling for Smoking Cessation
Tobacco use remains persistently high across South Asia, despite numerous public health efforts, and continues to significantly contribute to the burden of non-communicable diseases (NCDs) such as cardiovascular disease…
- Conditions
- Tobacco Cessation, Health Warning Label, Hypertension, Non Communicable Chronic Diseases
- Trial name
- NCT07098065
- Testing
- Graphical health warnings, Graphical health warnings plus pharmacist-led counselling, Routine pharmacy services (no intervention)
- Where
- Bangladesh
- Volunteers
- 3,400 people
- Sponsor
- Hitotsubashi University
Smoking Cessation, Weight Gain
Exenatide for Smoking Cessation and Prevention of Weight Gain
The purpose of this study is to determine if exenatide improves end-of-treatment smoking abstinence rates and to determine if exenatide mitigates post-cessation weight gain.
- Trial name
- NCT05610800
- Testing
- Exenatide 2 milligram (mg) Injection, Nicotine patch, Smoking Cessation Counseling
- Where
- 2 sites in United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Abuse Tobacco, Exposure
Perceptions of Vaping Products
This clinical trial studies the effects, appeal, and abuse liability of 6-methyl nicotine (metatine) electronic cigarettes among young adults.
- Trial name
- NCT06868368
- Testing
- Biospecimen Collection, Survey Administration, Vaping Topography
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
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