Clinical trials: Tobacco Consumption
Cigarette Smoking
The Impact of Innovative Tax Proposals on Purchase Patterns
This study will investigate the effect of four tax proposals (i.e. Tobacco Parity, Nicotine-Content, Harm-Reduction, and Modified Risk Tobacco Product-related taxes) on tobacco product purchasing patterns.
- Trial name
- NCT05370313
- Testing
- Market Price Condition (control), Tobacco Parity Tax Condition, Nicotine-Content Tax Condition
- Where
- 2 sites in United States
- Volunteers
- 285 people
- Sponsor
- Virginia Polytechnic Institute and State University
Community Health Services, Respiratory Disease
INSPIRE Respiratory Health Program in Botucatu, São Paulo, Brazil
The goal of this observational study is to evaluate the implementation of the INSPIRE program and to plan actions for the preparation, coordination, monitoring, diagnosis, and treatment of respiratory diseases in the municipality…
- Conditions
- Community Health Services, Respiratory Disease, Tobacco Smoking
- Trial name
- NCT06673225
- Testing
- Analysis of results
- Where
- Brazil
- Volunteers
- 2,000 people
- Sponsor
- UPECLIN HC FM Botucatu Unesp
Nicotine Dependence
Transcranial Direct Current Stimulation in a Smoking Cessation Trial
The purpose of this study is to determine the effectiveness of transcranial direct current stimulation (tDCS) plus nicotine patch as a viable smoking cessation program for nicotine dependent smokers.
- Trial name
- tDCS (NCT01710410)
- Testing
- active transcranial Direct Current Stimulation
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
HIV, Smoking
A Patient-Oriented Research Mentoring Program in Tobacco Dependence and Implementation Science Research
The objective of this trial is to evaluate the effectiveness of "nudges" to clinicians, patients, or both in increasing referral to, and engagement with, tobacco use treatment services (TUTS) for HIV patients versus usual care.
- Conditions
- HIV, Smoking, Tobacco Use, Nicotine Dependence
- Trial name
- NCT05852860
- Testing
- Clinician Nudge, Patient Nudge
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Alcohol Use Disorder, Hiv
Off-Label Medications for Alcohol Use Disorder Among Patients With HIV: Pilot Study 2
This study seeks to determine the feasibility, acceptability, and preliminary efficacy of an intervention consisting of off-label use of a medication with strong efficacy data for alcohol use disorder (AUD) with medical…
- Conditions
- Alcohol Use Disorder, Hiv, Tobacco Use Disorder
- Trial name
- HARP (NCT06006143)
- Testing
- Varenicline
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Yale University
Nicotine Dependence
Effects of Progesterone on IV Nicotine Induced Changes on BOLD fMRI Signal, Hormones and Subjective Ratings of Stimulant Drugs
The proposed clinical studies will analyze the interactions between progesterone, nicotine, fMRI measures of patterns of brain activity, covariance with endocrine hormones, mood and cardiovascular measures.
- Trial name
- NCT01589068
- Testing
- Intravenous Nicotine, Progesterone
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mclean Hospital
Nicotine Dependence
Extinction Based Treatment for Nicotine Dependence
The purpose of this study is to test two quit smoking therapies and to study brain function while each therapy is being used. You will be randomly assigned (like flipping a coin) to one of the two groups.
- Trial name
- Extinction01 (NCT00831155)
- Testing
- Nicotine Patches, Denicotinized Cigarettes
- Where
- United States
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- Duke University
Smoking, Cigarette Smoking
The Effects of IQOS Use on Cigarette Smoking Behaviors
This within-subjects study aims to evaluate the effects of IQOS use on combustible cigarette smoking behaviors among 100 cigarette smokers who completed the study.
- Conditions
- Smoking, Cigarette Smoking, Tobacco Use
- Trial name
- IQOS (NCT05076708)
- Testing
- IQOS
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Nicotine Addiction
Effects of ABT-089 on Smoking Abstinence Symptoms and Reward
This Phase IIa within-subject, cross-over pilot study will evaluate the effects of ABT-089 (an experimental medication not approved by the FDA) when administered as 40mg oral once daily dose for 10 days, compared to placebo, on…
- Trial name
- NCT01756053
- Testing
- ABT-089
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Pennsylvania
Vaping Teens, Vaping Behaviors
Developing an E-Cigarette Cessation Intervention for Hispanic/Latina(o) Youth in Florida: The BReATHE Study
Electronic (e-)cigarettes are the most used nicotine product among U.S. youth. Hispanic/Latino (H/L) youth are at greater risk for e-cigarette use, yet few evidence-based cessation programs exist for youth, and even fewer are…
- Conditions
- Vaping Teens, Vaping Behaviors, Vaping Cessation, Tobacco Use Disorder
- Trial name
- NCT07192601
- Testing
- E-cigarette Cessation Manual
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Florida International University
Pregnancy
Tobacco Use in Pregnancy Intervention for Cessation
The proposed project will test the effectiveness of the novel delivery of an established tobacco cessation treatment among pregnant women in Kentucky.
- Trial name
- ToPIC (NCT03442530)
- Testing
- ToPIC, Tobacco Treatment As Usual (TTAU)
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Kristin Ashford
Tobacco Use Disorder
Study of EMB-001 as a Potential Smoking Cessation Treatment
EMB-001 is a combination of 2 drugs: the cortisol synthesis inhibitor, metyrapone (Metopirone®), and the benzodiazepine receptor agonist, oxazepam (original trade name Serax®; now marketed as oxazepam (generic) only).
- Trial name
- NCT04933916
- Testing
- EMB-001
- Where
- 2 sites in United States
- Volunteers
- 16 people
- Sponsor
- Embera NeuroTherapeutics, Inc.
Tobacco Use Disorder
Effects of GTS-21 on Smoking Behavior and Neurocognitive Functions
Attempts to quit cigarette smoking are often accompanied by negative mood and problems in attention and memory. These effects, in turn, may contribute to smoking relapse.
- Trial name
- NCT02432066
- Testing
- GTS-21
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Tobacco Use Disorder
Combining a Smoke Ending Aid With Behavioral Treatment - 1
The purpose of this study is to combine a smoke ending aid with behavioral treatment.
- Trial name
- NCT00006151
- Testing
- Behavioral Therapy
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Peter Gariti
Tobacco Use, Pollution; Exposure
FRESHAIR4Life: Building the Case for Action
The goal of this observational study is to understand the burden and determinants of tobacco use and air pollution (AP) exposure among mid- to late adolescents in Greece, the Kyrgyz Republic, Pakistan, Romania, and Uganda.
- Conditions
- Tobacco Use, Pollution; Exposure, Non-communicable Disease
- Trial name
- NCT06074939
- Volunteers
- 1,750 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Copd, Smoking Cessation
Addressing Psychological Risk Factors Underlying Smoking Persistence in COPD Patients: The Fresh Start-II Study
Chronic Obstructive Pulmonary Disease (COPD) is caused primarily by smoking and smoking cessation is the first-line treatment for slowing disease progression.
- Conditions
- Copd, Smoking Cessation, Nicotine Dependence, Tobacco Use
- Trial name
- NCT04646174
- Testing
- Unified Protocol adapted for smoking cessation, American Lung Association self-management strategies for smoking cessation
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Rush University Medical Center
Nicotine Use Disorder
Neural Basis of Eating Behavior in Abstinent Smokers
The purpose of this research study is to better understand why people gain weight when they quit smoking by examining food intake and changes in brain activity in smokers when they are smoking as usual compared to when they have…
- Trial name
- SIT (NCT03438188)
- Testing
- Practice Quit Attempt
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Smoking
Varenicline for Light Smokers
The purpose of this study is to determine if varenicline is effective in treating tobacco dependence in adults who smoke 5-10 cigarettes per day.
- Trial name
- ChanLight (NCT01639560)
- Testing
- Varenicline
- Where
- United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Smoking Patients
Efficacy of a Nurse-based Intervention on Tobacco Consumption in Hospitalized Patients
Tobacco consumption is a major public health problem, ranking second in the leading cause of morbidity and mortality worldwide, in 2010.
- Trial name
- HOT (NCT03281642)
- Testing
- Tobacco management
- Where
- France
- Volunteers
- 430 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Moderate or Severe Tobacco Use Disorder
Analysis and Evaluation of Smoking Treatment With Cytisine
The lack of clinical studies on the use of Cytisine in the treatment of the cessation of smoking, the need to find effective therapeutic alternatives and the opportunity to reduce costs related to the complications of cigarette…
- Trial name
- NCT06439303
- Testing
- Cytisine 1,5 mg
- Where
- Italy
- Volunteers
- 65 people
- Sponsor
- Regina Elena Cancer Institute
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