Clinical trials: Tobacco Consumption
Tobacco Use Cessation, Cancer
Comprehensive Tobacco Cessation for Cancer Patients and Survivors
The purpose of this research study is to learn how best to incorporate tobacco cessation treatment into clinical care for cancer patients, survivors, and caregivers.
- Trial name
- NCT05805722
- Testing
- Behavioral counseling for tobacco cessation
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Virginia Commonwealth University
Neuropathic Pain, Anxiety Disorder/Anxiety State
Predictive and Impact of Pain After 6 Months of Radiotherapy, in Head and Neck Cancer
Head and neck cancers are a source of complications and after-effects related to the disease and treatment. These cancers and their treatment alter the quality of life of patients and generate pain with physical and psychological…
- Conditions
- Neuropathic Pain, Anxiety Disorder/Anxiety State, Pain, Chronic, Alcohol Use Disorder
- Trial name
- DIP-CAOS (NCT05505188)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Caen
Nicotine Dependence
Smoking While on Transdermal Nicotine Replacement Therapy: Effects on Craving and Cessation
Smoking while on nicotine patches will help subjects to reduce their expired carbon monoxide levels from the levels they were before they started using the patch. Subjects will also decrease their daily consumption of cigarettes.
- Trial name
- NCT00289653
- Testing
- Nicoderm
- Where
- Canada
- Volunteers
- 23 people
- Sponsor
- Centre for Addiction and Mental Health
Tobacco Use Cessation
American Indians STOp Smoking by Mobile Phone
In an attempt to reduce smoking-related health disparities, investigators will implement a text messaging-based smoking cessation intervention in collaboration with state quit lines.
- Trial name
- AI STOMP (NCT03168451)
- Testing
- Culturally Tailored Text Messages
- Where
- United States
- Volunteers
- 346 people, healthy volunteers welcome
- Sponsor
- Washington State University
Cigarette Smoking
Puff Biofeedback to Reduce Smoking Reinforcement
The purpose of the study is to examine the effects of a novel bio-behavioral paradigm, entitled, Puff Topography Biofeedback Training, compared to a control condition, in reducing stress-induced smoking reinforcement.
- Trial name
- NCT05644002
- Testing
- Puff Topography Biofeedback Training, Control
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- Rutgers, The State University of New Jersey
Psychiatric Disorders
TORCH - Transdiagnostic Observation of Risk Factors, Craving and Health Behaviours in Psychiatric Patients
Mental disorders are often accompanied by health-risk behaviours, psychiatric comorbidity, and reduced functioning. TORCH investigates transdiagnostic mechanisms underlying multiple health behaviour change in adult psychiatric…
- Trial name
- TORCH (NCT07844798)
- Testing
- person-centred interventions
- Where
- Germany
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Jacobs University Bremen gGmbH
HIV Associated Cognitive Motor Complex
Effect of Galantamine on Inflammation and Cognition
This study tests whether galantamine (GAL) reduces HIV-related inflammation and cognitive deficits. In this double-blind placebo-controlled crossover study, HIV-infected individuals (N=120; 60 smokers and 60 non-smokers) will be…
- Trial name
- CHI (NCT03384784)
- Testing
- Galantamine
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- University of Pennsylvania
Tobacco Use Disorder, Smoking Cessation
Deep rTMS and Varenicline for Smoking Cessation
The purpose of this study is to investigate the effect of deep repetitive transcranial magnetic stimulation (rTMS) using the insula H-coil on smoking outcomes in smokers receiving varenicline.
- Trial name
- NCT04083144
- Testing
- Deep Repetitive Transcranial Magnetic Stimulation (Active), Varenicline
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Centre for Addiction and Mental Health
Tobacco Use Cessation
mHealth Messaging to Motivate Quitline Use Quitting
The mHealth Messaging to Motivate Quitline Use and Quitting, or "M2Q2" study, is a collaborative research project for a mobile health intervention designed to motivate smoking cessation and encourage access to counseling.
- Trial name
- M2Q2 (NCT03567993)
- Testing
- Comparison, Intervention
- Where
- Vietnam
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Tobacco Use Disorder
Nicotine Replacement Treatment for Pregnant Smokers - 1
Smoking during pregnancy is an important modifiable cause of poor pregnancy outcomes. Even with augmented behavioral interventions, smoking cessation rates in pregnancy trials rarely exceed 20%.
- Trial name
- NCT00115687
- Testing
- 2 mg nicotine polacrilex
- Where
- 4 sites in United States
- Volunteers
- 250 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Nicotine Dependence, Cigarettes
The Role of Nicotine Dose and Route of Delivery in Affecting Adoption of E-cigarettes and Reducing Exposure to Toxic Combustion Products
This study plans to investigate whether using electronic cigarettes (e-cigarettes) or skin patches containing nicotine affects switching from smoking conventional combustible (burning) cigarettes.
- Trial name
- ENDS-Switch (NCT03492463)
- Testing
- Nicotine patch, E-cigarettes, Non-nicotine e-cigarettes
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Duke University
Tobacco Use
Electronic Cigarette Unit Price Manipulations in the Experimental Tobacco Marketplace
Electronic cigarettes (e-cigarettes) may be a safer alternative to conventional cigarettes and are available in a broad range of nicotine strengths.
- Trial name
- NCT03843047
- Testing
- 3 mg/mL nicotine strength e-liquid, 6 mg/mL nicotine strength e-liquid, 12 mg/mL nicotine strength e-liquid
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Virginia Polytechnic Institute and State University
Nicotine Addiction
A Smoking Intervention Study Using Scheduled Gradual Reduction With Varenicline to Help With Cessation
This study has three main aims. Aim 1: To provide initial data on the efficacy of combined Scheduled Gradual Reduction (SGR) and Varenicline (VN) for smoking cessation, by assessing abstinence and levels of smoking at 2 time…
- Trial name
- NCT01772641
- Testing
- Scheduled Gradual Reduction + Varenicline, Basic Advice + Varenicline
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Nicotine Dependence, Cigarette Smoking
Lemongrass (Cymbopogon Citratus) on Nicotine Dependence, Cotinine Levels, and Related Biomarkers in Adult Smokers
The goal of this clinical trial is to learn whether lemongrass (Cymbopogon citratus) inhaler and liquid vapor interventions affect nicotine dependence and related biological and behavioral outcomes in adult smokers.
- Conditions
- Nicotine Dependence, Cigarette Smoking, Tobacco Use Disorder, Psychological Stress
- Trial name
- CCIVS (NCT07366294)
- Testing
- Lemongrass Inhaler, Lemongrass Liquid Vapor, Lemongrass Inhaler and Liquid Vapor
- Where
- Indonesia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Titin Andri Wihastuti
Smoking, Cigarette, Smoking E-cigarette
Imaging Sex Differences in Smoking-Induced Pulmonary Inflammation
The purpose of this research is to measure the extent of lung inflammation between different groups of participants using a radioactive tracer called [18F]NOS.
- Conditions
- Smoking, Cigarette, Smoking E-cigarette, Healthy Volunteer
- Trial name
- NCT03721822
- Testing
- [18F]NOS
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Tobacco Use Cessation
Smoking Cessation Support for Patients With Rheumatologic Diseases Via WhatsApp
Smoking cessation support for patients with rheumatologist diseases is an underestimated issue. In the previous prospective cohort study the investigators determined that with the brief cessation interventions 63.5% of smokers…
- Trial name
- NCT06219551
- Testing
- Mobile messages via What's App
- Where
- Turkey (Türkiye)
- Volunteers
- 220 people
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Nicotine Dependence, Cigarettes
Acute Oral Effects of Heated Tobacco Products
Heated tobacco products (HTP) are devices which heat, but not burn tobacco. They do not produce cigarette smoke but rather an aerosol. HTPs are marketed as less harmful alternatives to smoking.
- Trial name
- NCT05538702
- Testing
- IQOS 3.0 DOU with bland taste unit (Heated Tobacco Product), IQOS 3.0 DUO with menthol taste unit (Heated Tobacco Product), Marlboro Gold (Conventional cigarette)
- Where
- Hungary
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Cigarette Smoking
Analysis of Lipid Biomarkers of Exposure and Host Response
The purpose of this prospective, open-label, clinical trial is to establish the feasibility and validity of exhaled breath condensate (EBC) biomarkers for use in studies designed to evaluate harm reduction strategies of smoking.
- Trial name
- NCT00493831
- Testing
- nicotine polacrilex, transdermal system or inhaler
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Nebraska
Tobacco Use
Comparative Tobacco Interventions for Individuals With Severe and Persisting Behavioral Health Disorders
The aim of this pilot intervention is to examine the acceptability of a harm reduction intervention approach to tobacco use for individuals with serious behavioral health disorders and its association with a decrease in smoking.
- Trial name
- THRRP (NCT04523948)
- Testing
- Behavioral and pharmacological support to reduce combustible tobacco use.
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Rose Research Center, LLC
Cigarette Smoking, Psychological Interventions
Efficacy and Neuroimaging Mechanisms of Smoking Cessation in China
This proposed project is to assess the efficacy of CBT-based digital smoking cessation interventions in China, as well as explore its neuroimaging mechanisms.
- Conditions
- Cigarette Smoking, Psychological Interventions, Smoking Cessation
- Trial name
- NCT05788068
- Testing
- Cognitive behavior therapy
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Sir Run Run Shaw Hospital
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