Clinical trials: Tobacco Product
Smoking Cessation
Post-Discharge Smoking Cessation Strategies: Helping HAND 4
This randomized controlled trial will compare the effectiveness of two models of post-discharge tobacco cessation treatment for adult smokers admitted to 3 U.S. hospitals.
- Trial name
- HH4 (NCT03603496)
- Testing
- Transitional Tobacco Care Management (TTCM), eReferral to State Tobacco Quitline (QL), Nicotine replacement therapy
- Where
- 3 sites in United States
- Volunteers
- 1,416 people
- Sponsor
- Massachusetts General Hospital
Smoking, Cigarette
Smoking and Peptidoglycan Recognition Protein-1 and Initial Periodontal Therapy
A total of 40 patients with CP (20 smokers (S+CP) and 20 nonsmokers (S-CP)) and 40 periodontally healthy subjects (20 smokers (S+PH) and 20 nonsmokers (S-PH)), comprising 80 subjects, were included in this study.
- Trial name
- NCT03915730
- Testing
- Initial periodontal therapy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Tobacco Reduction
Evaluation of a Cognitive Behavioral Smoking Reduction Program
The aim of this study is to evaluate a new cognitive behavioral smoking reduction program for ambulant patients in a three-armed study design.
- Trial name
- NCT02337400
- Testing
- Cognitive behavioral smoking reduction program "Smoke_less", 15 minute counseling interview
- Where
- Germany
- Volunteers
- 155 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Smoking Cessation, Smokeless Tobacco
In-vivo Extraction of Pb, Cd and TSNA From Swedish Snus
In an open label, randomized, two-way cross-over study, 32 male healthy regular snus users will be given repeated doses of four different types of portion snus: "General", "Catch", "Catch Mini" and "Catch Dry Mini".
- Conditions
- Smoking Cessation, Smokeless Tobacco, Harm Reduction
- Trial name
- SMWS03 (NCT01369693)
- Testing
- Buccal administration of nicotine
- Where
- Sweden
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Contract Research Organization el AB
Smoking Cessation
Implementing Tobacco Treatment in Low Dose CT Lung Cancer Screening Sites
This study is to help determine the most effective type or combination of treatments to offer patients seeking lung cancer screening who are smokers to help them reduce the number of cigarettes they smoke, or quit smoking.
- Trial name
- NCT03315910
- Testing
- Motivational Interviewing (MI), Nicotine Replacement Therapy (NRT), Nicotine Lozenge
- Where
- 18 sites in United States
- Volunteers
- 807 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Hookah Smoking
Optimizing Risk Messages for Waterpipe Tobacco Cessation in Young Adults
The objective of this study is to examine whether messages conveying the harms and addictiveness of waterpipe (i.e., hookah) tobacco delivered by mobile phone multimedia messaging (MMS) are effective for promoting hookah tobacco…
- Trial name
- NCT03595280
- Testing
- Hookah tobacco risk messages
- Where
- 2 sites in United States
- Volunteers
- 349 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Nicotine Dependence
Do Flavors Increase the Addiction Potential of Nicotine?
The FDA has concluded that flavors (e.g. menthol) are associated with greater addiction potential in tobacco cigarettes (Gottlieb March 13, 2019).
- Trial name
- NCT04696380
- Testing
- Nicotine, JUUL e-cigarette
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Tobacco Use Disorder
Acute Effects of Smoking on Airway Dendritic Cells
Airway dendritic cells control pulmonary immune responses to inhaled particles. It is the aim of the present study to investigate the acute effects of smoking on the number and surface molecule expression of human airway…
- Trial name
- NCT00740896
- Testing
- Smoking
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Rostock
Tobacco Dependence
Use of Nicotine Pouches Among Daily Smokers
The purpose of this clinical trial is to understand the health effects of a new oral nicotine pouch, and also to understand if this product can help reduce traditional cigarette smoking. The main aims are: 1.
- Trial name
- NCT06043362
- Testing
- 0 mg nicotine pouch, 3 mg nicotine pouch, 6 mg nicotine pouch
- Where
- 2 sites in United States
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Smokeless Tobacco Cessation
Testing ANSOS for Efficacy in Multi-Tribal Urban Communities
This is a wait-list control trial to test for efficacy of the All Nations Snuff Out Smokeless (ANSOS) recreational tobacco cessation program in multi-tribal American Indian (AI) communities.
- Trial name
- NCT06566703
- Testing
- All Nations Snuff Out Smokeless, Healthy Living
- Where
- United States
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- Lehigh University
Acute Coronary Syndrome, Tobacco Use
Integrated Smoking Cessation and Mood Management for ACS Patients
Quitting smoking following acute coronary syndrome can reduce mortality up to 50%. However, depression and smoking are highly co-morbid and depressed mood may interfere with cessation and independently predicts mortality.
- Trial name
- PACES (NCT03029923)
- Testing
- Experimental: Behavioral Activation Treatment for Cardiac Smokers (BAT-CS), Smoking cessation plus Health and Wellness
- Where
- United States
- Sponsor
- The Miriam Hospital
Tabacco Use Disorder, rTMS
Personalized Brain Stimulation to Help Veterans Quit Smoking
Cigarette smoking is a significant public health concern for Veterans. Encouraging smoking cessation continues to be a top priority for the Veterans' Administration as Veterans who use tobacco experience negative health effects…
- Trial name
- VICTOR (NCT07050862)
- Testing
- Transcranial Magnetic Stimulation, Personalized-image-guided and E-field-modeling dose rTMS (precision TMS)
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- VA Office of Research and Development
Nicotine Use Disorder
Identify the Optimal TMS Target to Modulate Reward Activity
Our primary goal will be to identify the optimal prefrontal-cingulate target by systematically measuring the efficacy of various image-based targeting techniques to increase the reward positivity using the 10-Hz TMS protocol in…
- Trial name
- NCT05766254
- Testing
- Active 10-Hz TMS to the DLPFC
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Rutgers, The State University of New Jersey
Smoking, Tobacco
Respiratory Function and Oxygenation in Smokers and Non-smokers
This study aimed to compare respiratory function, exercise capacity, and intercostal muscle oxygenation in healthy smokers and non-smokers.
- Trial name
- NCT07027956
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Kirsehir Ahi Evran Universitesi
Tobacco Use Disorder
Social and Monetary Incentives for Smoking Cessation at Large Employers
The investigators will conduct a cluster randomized controlled trial of several behavioral interventions for smoking cessation among a sample of employees at large workplaces in the Bangkok metropolitan area.
- Trial name
- SMILE (NCT02421224)
- Testing
- Usual Care, Deposits, Small Individual Bonus
- Where
- Thailand
- Volunteers
- 4,190 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Smoking Cessation
Partnering With Food Bank to Provide Tobacco Treatment to Underserved Smokers
This study evaluates the efficacy and economic impact of a theoretically-based, fully automated, interactive smartphone-based smoking cessation intervention.
- Trial name
- NCT05004662
- Testing
- Smartphone-delivered automated treatment, Nicotine patch, Counseling
- Where
- United States
- Volunteers
- 502 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Health Communication, Smoking
Messages About Reduced Nicotine in Combusted Tobacco Products
The investigators will conduct a message-exposure experiment with nationally representative samples of smokers, dual-users (cigarettes and e-cigarettes), and young adult non-smokers (aged 18-29).
- Conditions
- Health Communication, Smoking, Smoking, Tobacco, Smoking Behaviors
- Trial name
- NCT05506046
- Testing
- Reduced nicotine message exposure, Modified risk message exposure, Combined message exposure (reduced nicotine + modified risk)
- Where
- United States
- Volunteers
- 1,901 people
- Sponsor
- Georgia State University
Smoking Cessation, Smoking, Cigarette
Preloaded Combination Nicotine Replacement Therapy on Smoking Cessation of Adult Population in Kazakhstan
Randomized, controlled, two-armed, single-blinded, superiority trial with 1:1 allocation ratio Nicotine Replacement Therapy(NRT)
- Conditions
- Smoking Cessation, Smoking, Cigarette, Smoking Behaviors
- Trial name
- NCT05484505
- Testing
- Nicotine patch, Nicotine gums, Brief Advice (5 A's & 5 R's), Nicotine Patch: Preloading for 4 weeks
- Where
- 2 sites in Kazakhstan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Nazarbayev University
Smoking Cessation, Tobacco Smoking
App for Pregnancy Smoking Cessation With Peer Support
The objectives of this project are to develop, implement, and test the feasibility and effectiveness of an artificial intelligence adaptive mobile pregnancy tobacco cessation app-based intervention using deep tailoring and a…
- Trial name
- SFT (NCT05337722)
- Testing
- SFT 2.0, Active control
- Where
- Romania
- Volunteers
- 786 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Tobacco Use Disorder, Schizophrenia
Nicotine and Sensorimotor Replacement for Smoking in Smokers With Schizophrenia
The objective of this study is to investigate the relative contributions of nicotine replacement and sensorimotor replacement (i.e., smoking denicotinized cigarettes) on abstinence-induced smoking urges, withdrawal-related…
- Trial name
- NCT01213524
- Testing
- sensorimotor replacement, 42 mg transdermal nicotine replacement, usual brand smoking
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Brown University