Clinical trials: Tobacco Products
Schizophrenia, Tobacco Use Disorder
Effect of Bupropion on Smoking Behavior in Smokers With Schizophrenia
Many individuals with schizophrenia smoke cigarettes but little is known about the factors that control smoking in people with schizophrenia.
- Trial name
- NCT00218231
- Testing
- 300 mg/day bupropion-sr, 0 mg/day bupropion-sr
- Where
- 2 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Smoking
Bio-Behavioral Predictors of the Efficacy of Nicotine Replacement Therapy (NRT)
The purpose of this research study is to: 1. compare the effectiveness of a nicotine patch and nicotine nasal spray for smoking cessation; and 2.
- Trial name
- NCT00326781
- Testing
- Nicoderm Transdermal Patch, Nicotine Nasal Spray
- Where
- United States
- Volunteers
- 674 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Smoking, Smoking Cessation
Hollings Cancer Center Varenicline Sampling Study
The purpose of this study is to learn what happens when people are given a free, 4-week, sample of varenicline, a smoking cessation medication.
- Conditions
- Smoking, Smoking Cessation, Smoking, Tobacco, Smoking, Cigarette
- Trial name
- NCT03742154
- Testing
- Varenicline 0.5 MG
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- Medical University of South Carolina
Nicotine Dependence
Effectiveness of GW468816, an NMDA Glycine Site Antagonist, for Prevention of Relapse to Smoking
The purpose of this study is to evaluate the efficacy of the glycine antagonist, GW468816, compared with placebo on duration of abstinence and rates of relapse in recently quit female smokers in a randomized, double-blind…
- Trial name
- NCT00218465
- Testing
- GW468816
- Where
- 2 sites in United States
- Volunteers
- 264 people
- Sponsor
- Massachusetts General Hospital
Tobacco Dependence
Nicotine Lozenge or Tobacco-Free Snuff for Smokeless Tobacco Reduction
Smokeless tobacco (ST) is a known human carcinogen. Long-term ST use is known to increase the risk for oropharyngeal cancer. Extant literature on cigarette smokers suggests that smoking reduction increases smoking abstinence…
- Trial name
- NCT01018394
- Testing
- nicotine lozenges, tobacco-free snuff
- Where
- 2 sites in United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Tobacco Use Disorder
Fresh Lime Alone for Smoking Cessation
The purpose of this study is to determine whether fresh lime alone is effective for smoking cessation.
- Trial name
- LIM (NCT01333202)
- Testing
- Fresh lime
- Where
- Thailand
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Thai Health Professional Alliance Against Tobacco
Smoking
Reduced Exposure Study Using THS 2.2 Menthol With 5 Days in a Confinement Setting Followed by 86 Days in an Ambulatory Setting
Evaluate if the ad libitum use of the THS 2.2 Menthol (mTHS), a candidate Modified Risk Tobacco Product, for 5 days in confinement, and after 86 days in an ambulatory setting, by apparently adult healthy smokers results in a…
- Trial name
- NCT01989156
- Testing
- THS 2.2 Menthol (mTHS 2.2), Menthol Conventional Cigarette (mCC), Smoking Abstinence (SA)
- Where
- 2 sites in United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Tobacco; Use, Harmful
The Influence of Electronic and Traditional Cigarettes Smoking on Hemodynamic Parameters
It is intended to examine 50 healthy volunteers aged 18 - 60 years. 12-hour abstinence from tobacco smoke, alcohol or coffee before the experiment will be required.
- Trial name
- EPAPHemo (NCT03037775)
- Testing
- Baseline, e-cigarette without nicotine, e-cigarette with nicotine
- Where
- Poland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Hiv, Tobacco Smoking
Accelerated Transcranial Magnetic Stimulation (TMS) for Smoking Cessation in People Living With HIV/AIDS (PLWHA)
To demonstrate whether four sessions of TBS improves attentional bias and craving in PLWHA smokers compared to four sessions of sham stimulation.
- Trial name
- NCT05295953
- Testing
- TBS
- Where
- 2 sites in United States
- Volunteers
- 4 people
- Sponsor
- Gopalkumar Rakesh
Nicotine Dependence
Doctors' Perspective on Tobacco Addiction
ABSTRACT Aim: Our study aimed to determine the approaches of our physicians to the smoking habits of their patients other than those with pulmonary diseases.
- Trial name
- NCT06163872
- Testing
- survey study
- Where
- Turkey (Türkiye)
- Volunteers
- 941 people
- Sponsor
- Karadeniz Technical University
Smoking, Smoking Habit
PRogetto Salute Parma
This project from the University Hospital of Parma (AOUPR) aims to verify the feasibility of a prevention program in our district, relying on advanced technological resources and highly experienced team in lung cancer early…
- Conditions
- Smoking, Smoking Habit, Smoking, Tobacco, Smoking, Cigarette
- Trial name
- PSP (NCT04282694)
- Testing
- Low-dose computed tomography (LDCT)
- Where
- Italy
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Parma
Healthy Volunteers
A Study to Assess Tobacco-related Biomarkers of Exposure in Smokers Using myBlu E-cigarettes
The purpose of this study is to assess changes in exposure to selected harmful and potentially harmful substances related to tobacco/nicotine use when adult smokers switch from their usual brand of combustible cigarettes to the…
- Trial name
- NCT04019626
- Testing
- Continue-smoking, myblu Tobacco 2.5%, myblu Tobacco 4.0%
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Fontem Ventures BV
Smoking ( Cigarette), Women
Smoking, Pain Threshold, and Hand Strength in Women
This study aims to investigate the effects of smoking on pain threshold, cervical position sense, and grip strength in women. Measurements will include pressure pain threshold (PPT), cervical position sense (CPS), grip strength…
- Conditions
- Smoking ( Cigarette), Women, Pain
- Trial name
- NCT07611760
- Testing
- observational study
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Severe Chronic Obstructive Pulmonary Disease
Evaluation of Benefit of Nebulized Bronchodilators at Home in Severe Chronic Obstructive Pulmonary Disease and Very Severe Steady State
Design studies of nebulization in COPD does not respond adequately to the clinically relevant question: the intervention of administering nebulized bronchodilators at home it is likely to make a profit, compared to the standard…
- Trial name
- Nebuadom (NCT02103374)
- Testing
- Atrovent + Bricanyl or Atrovent + Ventoline
- Where
- 13 sites in France
- Volunteers
- 45 people
- Sponsor
- University Hospital, Tours
Cigarette Smoker, Current Smoker
Nicotine Delivery From Novel Non-Tobacco Electronic System in Smokers
This randomized pilot clinical trial studies nicotine delivery from novel non-tobacco electronic system (ENDS) in smokers. Studying the levels of nicotine delivered by various types and brands of ENDS to the bloodstream, and…
- Conditions
- Cigarette Smoker, Current Smoker, Healthy Subject
- Trial name
- ENDS (NCT02575885)
- Testing
- Electronic Cigarette, Laboratory Biomarker Analysis, Pharmacological Study
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
Tobacco Toxicant Exposure
Determining Levels of [D10] Phenanthrene Tetraol in Smokers' Urine
The purpose of this research study is to better understand how people respond to cancer-causing chemicals in cigarette smoke. Some people are able to get rid of these chemicals as harmless agents while others suffer damage to…
- Trial name
- NCT01092650
- Testing
- Deuterated phenanthrene
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Smoking, Tobacco Use Cessation
Group Therapy for Nicotine Dependence: Mindfulness and Smoking
The goal of this behavioral research study is to create and study a Mindfulness-Based Addiction Treatment (MBAT) for nicotine dependence.
- Trial name
- NCT00297479
- Testing
- MBAT Group Therapy, Nicotine, Group Therapy
- Where
- United States
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Cardiovascular Disease
Dose-dependent Effects of Second-hand Smoke on Vascular Function
The purpose of this study is to determine the vascular effects of brief second-hand smoke exposure on normal healthy individuals.
- Trial name
- NCT01007760
- Testing
- Respirable suspended particles (RSP) PM 2.5 dose of second-hand smoke
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Substance Withdrawal Syndrome
Does Abstinence From E-cigarettes Produce Withdrawal Symptoms?
The purpose of this study is to see whether adults who use e-cigarettes every day experience symptoms of nicotine withdrawal when they stop using e-cigarettes for 6 days.
- Trial name
- NCT02825459
- Testing
- Abstinence from e-cigarettes
- Where
- 2 sites in United States
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Smoking Cessation, Tobacco Use Cessation
Financial Incentives for Smoking Treatment II
Financial incentives for motivating changes in health behavior, particularly for smoking and other morbid habits, are increasingly being tested by health insurers, employers, and government agencies.
- Trial name
- FIESTA II (NCT03979885)
- Testing
- Smoking cessation counseling (Quitline), Smoking cessation pharmacotherapy (e.g, nicotine replacement therapy), Financial incentives for smoking cessation
- Where
- 2 sites in United States
- Volunteers
- 1,058 people
- Sponsor
- University of California, Los Angeles
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