Clinical trials: Tobacco Reduction
Smoking Cessation, Smoking
Reducing Tobacco Related Health Disparities
The goal of this research study is to learn the effectiveness of telephone-based counseling on helping smokers change their smoking patterns.
- Trial name
- NCT00984724
- Testing
- Standard Treatment (ST), Telephone Counseling, Quitline
- Where
- United States
- Volunteers
- 639 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Tobacco Use
Remote Trial - Tobacco Product Standard (VLNC)
The goal of this pilot project is to explore the feasibility of a real-world marketplace study design examining the effects of a reduced nicotine product standard for cigarettes on smoking in the context of a flavor restriction…
- Trial name
- NCT06442384
- Testing
- Tobacco and non-tobacco e-cigarettes, Tobacco only e-cigarettes
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Masonic Cancer Center, University of Minnesota
Tobacco-Related Carcinoma
Episodic Future Thinking and Future Thinking Priming for Smoking Cessation
This trial studies the main and interactive effects of episodic future thinking and future thinking priming tasks on helping participants to quit smoking.
- Trial name
- NCT04297332
- Testing
- Behavioral Intervention, Informational Intervention, Nicotine Replacement
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
Smoking Cessation, Smoking Abstinence
Breathe 2 Project 3: Comprehensive Chronic Care
This study will evaluate Comprehensive Chronic Care (CCC), a healthcare treatment approach designed to increase smoking treatment engagement and abstinence among primary care patients who smoke.
- Trial name
- NCT05382221
- Testing
- Comprehensive Chronic Care, Standard Care
- Where
- 2 sites in United States
- Volunteers
- 979 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Secondhand Tobacco Smoke Exposure Reduction
Reducing Breast Cancer Risk in Korean American Women
The goals of the study are to develop a culturally and linguistically appropriate intervention to reduce SHS exposure for LEP Korean women using a family-focused intervention approach targeting Korean Americans ages 18 and above…
- Trial name
- NCT04079556
- Testing
- Tobacco LHW
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Smoking
Combined Treatment for Tobacco and Alcohol Use in Puerto Rico
Objectives: 1. Assess MAPS and MAPS+ effects on alcohol at-risk behaviors and smoking cessation. 2. Assess MAPS and MAPS+ effects on treatment mechanisms (increased self-efficacy, decreased temptations/craving, decreased stress…
- Trial name
- NCT00570804
- Testing
- Telephone Counseling, Telephone Assessments
- Where
- United States
- Volunteers
- 370 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Tobacco Addiction, Dual Tobacco Use
Reduced Nicotine Content Cigarettes and Tobacco Switching Behaviors
The main focus of this study is to determine the use of nicotine-containing products across the three experimental conditions. Subjects will be monitored to determine their continued use of assigned cigarettes, switching to other…
- Trial name
- NCT02000921
- Testing
- VLNC cigarettes, Combusted Products, Non-combusted products
- Where
- United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Smoking, E-Cig Use
Clinical Alternatives for Reducing Harm Using E-cigarettes
For patients in cancer care, quitting smoking is critical, but a significant portion of patients in cancer care refuse all components of tobacco treatment, even when offered free of charge.
- Conditions
- Smoking, E-Cig Use, Oncology
- Trial name
- CARE (NCT07039292)
- Testing
- Harm Reduction (E-cigarette switching), Standard of Care
- Where
- United States
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
The Study Focused on Reducing Tobacco Smoke Exposure for Child.
Effects of Tobacco Smoke Exposure on Epigenetic Signatures and Immunotoxicological Reactions
Researchers have noted that active smoke exposure was possibly related to epigenetic mechanism,and may further influence reactive immunotoxicological reaction on human beings.
- Trial name
- NCT01317628
- Testing
- Tobacco smoke reduction trial intervention program
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Smoking Reduction, Smoking Behaviors
Assessment of the Pivot Breath Sensor: Single-Arm Cohort Study
Prospective open label, single center study enrolling up to 220 participants to evaluate the effect of the Pivot Breath Sensor on a user's attitudes towards quitting smoking and smoking behavior.
- Conditions
- Smoking Reduction, Smoking Behaviors, Smoking, Tobacco, Smoking Cessation
- Trial name
- NCT04133064
- Testing
- Pivot Breath Sensor
- Where
- United States
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- Jennifer Marler, MD
Tobacco Use Disorder
Efficacy of Oral Tobacco Products Compared to a Medicinal Nicotine
For the primary goals, we hypothesize that 1) the oral tobacco product will be more efficacious than the medicinal nicotine product in substituting for smoking cigarettes; 2) among non-abstainers, the oral tobacco product will…
- Trial name
- NCT00710034
- Testing
- Oral tobacco, Nicotine Gum
- Where
- 2 sites in United States
- Volunteers
- 391 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Cannabis Use, Cannabis
Joint Effort 2.0: a Mobile Application With University Students
The purpose of this study is to evaluate quantitatively and qualitatively a mobile application, Joint Effort, targeting safe cannabis use among consumers.
- Conditions
- Cannabis Use, Cannabis, Cannabis Dependence, Cannabis Smoking
- Trial name
- JOINTEFFORT (NCT05620433)
- Testing
- Joint Effort, Brief normative feedback and standard information
- Where
- Canada
- Volunteers
- 354 people, healthy volunteers welcome
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
E-cigarette Use, Cigarette Smoking
Noncombustible Nicotine Delivery Systems as Potential Harm Reduction Tools for Persistent Cigarette Smokers
This between-subjects study aims to evaluate whether e-cigarettes (ECIGS) versus oral nicotine pouches (ONPS) more readily substitute for combustible cigarettes among 200 cigarette smokers.
- Conditions
- E-cigarette Use, Cigarette Smoking, Harm Reduction, Tobacco Use
- Trial name
- NCT06372899
- Testing
- E-cigarettes, Oral nicotine pouches
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Abramson Cancer Center at Penn Medicine
Smoking Cessation, Smoking
Testing the Efficacy of A Scalable, Telephone-Delivered, Guided Imagery Tobacco Cessation Intervention
The objective of this R01 application is to conduct a randomized controlled trial to test the efficacy of the Be Smoke Free, telephone-based, guided imagery (GI) intervention (IC) for smoking cessation compared to active…
- Conditions
- Smoking Cessation, Smoking, Smoking Reduction, Smoking, Cigarette
- Trial name
- NCT05277831
- Testing
- Guided Imagery Intervention, Standard Behavioral Control
- Where
- United States
- Volunteers
- 1,209 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Nicotine Dependence, Smoking, Cigarette
Isradipine Enhancement of Virtual Reality Cue Exposure for Smoking Cessation
The proposed study represents a crucial and important stage in translating basic research to strategies for treating nicotine dependence.
- Conditions
- Nicotine Dependence, Smoking, Cigarette, Smoking Cessation, Smoking Behaviors
- Trial name
- NCT03083353
- Testing
- Isradipine, Cue Exposure
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Jasper A. Smits
Nicotine Dependence
Brain/Craving Response to Smoking Cues After Oral Nicotine Pouch Use
Oral nicotine pouches (ONPs) are non-combustible nicotine products that may reduce cigarette craving and smoking cue-induced brain activity, supporting their potential as harm-reduction tools for adults who smoke cigarettes.
- Trial name
- NCT07698470
- Testing
- Oral Nicotine Pouch, Smoking Cue Reactivity Task
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Second Hand Tobacco Smoke
Reducing Second-hand Smoke Exposure Among Young Children in Rural China
Second-hand smoking (SHS) is a health hazard to infants and children, in whom it is associated with lower respiratory tract infections, wheezing, cough, middle ear infections and sudden infant death syndrome.
- Trial name
- NCT03567512
- Testing
- Smoking hygiene intervention
- Where
- China
- Volunteers
- 668 people, healthy volunteers welcome
- Sponsor
- Duke Kunshan University
Smoking, Tobacco Use Disorder
A Pilot Study to Evaluate Safety and Efficacy of CigRx™ in Smokers
A randomized, double-blind, active-controlled, crossover, pilot study to evaluate the safety and efficacy of CigRx™ Lozenge, a dietary supplement, in daily smokers in temporarily reducing the desire to smoke
- Trial name
- NCT01262170
- Testing
- CigRx Lozenge, Tobacco Lozenge
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Rock Creek Pharmaceuticals, Inc.
Tobacco Use Disorder, Smoking
Pilot Study to Evaluate the Safety and Efficacy of Ariva® Silver Wintergreen in Reducing Cigarette Craving in Smokers
Study to determine the safety and effectiveness of Ariva® Silver Wintergreen lozenge on reducing craving for a cigarette in daily smokers.
- Trial name
- NCT01337830
- Testing
- Ariva® Silver Wintergreen, Silver Wintergreen
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Star Scientific, Inc
Nicotine Dependence, Substance Use Disorders
Healthy People Initiative (HPI)
Addictions do not occur in isolation. Tackling addictions requires addressing social determinants such as isolation, homelessness, marginalization, and unemployment.
- Trial name
- HPI (NCT03506867)
- Testing
- Life skills, training, education and work/volunteer opportunities, Usual Care
- Where
- Canada
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute