Clinical trials: Tobacco Smoking
Smoking Cessation, Oxidative Stress
ESTxENDS Trial-Substudy on Oxidative Stress Induced by Electronic Nicotine Delivery Systems (ENDS) Measured in Urine
--> This is a substudy of the main ESTxENDS trial (NCT03589989). Oxidative stress outcomes should be considered secondary outcomes of the main smoking cessation outcome formulated in NCT03589989.
- Trial name
- ESTxENDS (NCT03612375)
- Testing
- ENDS (vaporizer/e-cig) and smoking cessation counseling, smoking cessation counseling
- Where
- 5 sites in Switzerland
- Volunteers
- 1,246 people, healthy volunteers welcome
- Sponsor
- University of Bern
Nicotine Addiction, Smoking Cessation
e-Cigarettes Versus NRT Gum for Smoking Cessation
This is a randomized trial comparing electronic cigarettes (e-Cigarettes) to nicotine gum for smoking cessation. Participants will be randomly assigned to either e-cigarette use or nicotine gum use during a quit attempt.
- Trial name
- NCT01925781
- Testing
- Nicotine polacrilex, STAM 1100mAh CE4 eGo Clearomizer
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Creighton University
Nicotine Dependence
Concurrent Bupropion / Varenicline for Smoking Cessation
This study focuses on the first step in developing an algorithm for maximizing quit-smoking success based on an adaptive approach, which changes treatment from the initial nicotine replacement therapy (NRT) when that treatment…
- Trial name
- ConNic4 (NCT01303861)
- Testing
- Varenicline, Bupropion, Nicotine patches
- Where
- 4 sites in United States
- Volunteers
- 702 people
- Sponsor
- Duke University
Smoking Cessation, Smoking
Evaluation of National Cancer Institute (NCI) Smoking Intervention Resources
This is an evaluative study of three National Cancer Institute (NCI) smoking cessation resources: specifically, the smokefree.gov and women smokefree.gov websites, and the CIS counseling phone calls.
- Conditions
- Smoking Cessation, Smoking, Nicotine Dependence
- Trial name
- NCI (NCT01342523)
- Testing
- CIS - telephone cessation quitline counseling, Lozenge - nicotine mini-lozenges, Emails - Brief smoking prevention messages
- Where
- United States
- Volunteers
- 1,034 people
- Sponsor
- University of Wisconsin, Madison
Hiv Infection, Lung Cancer
Early Lung Cancer Diagnosis in HIV Infected Population With an Important Smoking History With Low Dose CT: a Pilot Study
Early Lung Cancer diagnosis in a HIV-infected population with an important smoking history with low-dose CT: a pilot study: the HIV-CHEST study Objectives The main objective of this study is to evaluate the prevalence of lung…
- Trial name
- EP48 HIV CHEST (NCT01207986)
- Testing
- Low dose computed tomography (CT)
- Where
- France
- Volunteers
- 450 people
- Sponsor
- ANRS, Emerging Infectious Diseases
Field Cancerization for Cannabis Smokers
Effect of Cannabis and Cigarette Smoking on Oral Mucosa
The aim of this study is to detect P53 expression in clinically normal oral mucosa of cigarette smokers, simultaneous cigarette and cannabis smokers and non-smokers as a surrogate marker for field cancerization.
- Trial name
- NCT03334279
- Testing
- Cigarette smokers, Simultaneous cigarette and cannabis smokers
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cigarette Smoking Behavior
Project RESIST: Evaluating the Effects of Anti-smoking Inoculation Messages Among Young Adult Sexual Minority Women
Project RESIST is an R01 study funded by NCI focused on determining the effects of using culturally tailored inoculation approaches to increase resilience to tobacco marketing influences among young adult sexual minority women…
- Trial name
- NCT05499520
- Testing
- Culturally Tailored Anti-Smoking Messages
- Where
- United States
- Volunteers
- 2,591 people, healthy volunteers welcome
- Sponsor
- Abramson Cancer Center at Penn Medicine
Smoking
Reduced Exposure Study in Smokers Using the Tobacco Heating System 2.2 (THS 2.2) for 5 Days in a Confinement Setting
The overall goal of the study is to evaluate if the ad libitum use of the Tobacco Heating System 2.2 (THS 2.2) for 5 consecutive days by adult Japanese healthy smokers affects the levels of biomarkers of exposure for selected…
- Trial name
- NCT01970982
- Testing
- Tobacco Heating System (THS 2.2), Smoking abstinence (SA), Conventional cigarette (CC)
- Where
- Japan
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Smoking, Smoking Cessation
Tobacco Treatment Outreach to Reduce Disparities for Primary Care Populations
The objectives of this project are to develop and evaluate a multi-level approach to tobacco treatment for low-SES and minority patients.
- Trial name
- NCT01156610
- Testing
- Tobacco Treatment
- Where
- 2 sites in United States
- Volunteers
- 706 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Smoking Cessation
Study of Nicotine Replacement Therapy in Pregnancy
The overall objective of this study is to assess the effectiveness of NRT (Nicoderm patches) plus counselling treatment in women in the second and third trimester of pregnancy.
- Trial name
- NCT00744913
- Testing
- Nicoderm patches, Counselling
- Sponsor
- The Hospital for Sick Children
Smoking Cessation
Integrated Smoking Cessation Treatment for Low Income Community Corrections
This study recruited cigarette smokers under supervision in community corrections (e.g., probation, parole, drug courts, etc.) in the Birmingham, Alabama area.
- Trial name
- NCT01257490
- Testing
- counseling vs. advice
- Where
- United States
- Volunteers
- 689 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Nicotine Dependence
YMCA Exercise Intervention for Smoking Cessation Study
Cigarette smoking is the leading cause of death and disability in the United States. Although smoking has declined since 1964, it is still very common among some groups of people.
- Trial name
- NCT03080090
- Testing
- Aerobic exercise, Smoking Cessation Intervention
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Jasper A. Smits
Smoking, Tobacco, Smoking Cessation
Use of the Motivational Interviewing in the Treatment of Smokers in Groups in Primary Health Care
The objective of this study is to evaluate the efficacy of Motivational Interview (MI) on the smoking cessation rates of the smoking groups performed by the primary care teams of the Conceição Hospitalar Group, Porto Alegre…
- Trial name
- MITG (NCT03221010)
- Testing
- Motivational Interviewing, Traditional cognitive-behavioral approach
- Where
- Brazil
- Volunteers
- 600 people
- Sponsor
- Hospital Nossa Senhora da Conceicao
Obese, Cigarette-smoking
Naltrexone and Bupropion Combination on Obese,Smoking Patients With Schizophrenia
The purpose of this research is to observe the efficacy of Naltrexone and Bupropion combination on weight loss and smoking cessation from baseline to week 24 compare to placebo.
- Conditions
- Obese, Cigarette-smoking, Schizophrenia
- Trial name
- NCT02736474
- Testing
- Naltrexone, Bupropion
- Volunteers
- 22 people
- Sponsor
- Shanghai Mental Health Center
Smoking
Palatability of Experimental Cigarettes - Study 2
Smoking remains a leading cause of preventable disease and premature death worldwide. Approximately 1 out of every 5 deaths is associated with cigarette smoking, and roughly half of all daily smokers will die prematurely from…
- Trial name
- NCT01568905
- Testing
- Low level nicotine cigarette, Intermediate nicotine level cigarette, High level nicotine cigarette
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Multimorbidity, Tobacco Use Cessation
Impact of Multi-Component Interventions on High-Risk COPD Smokers
Study Participants: In our study, we focus on smokers who self-report a "current smoking" status or smoking cessation less than 6 months.
- Conditions
- Multimorbidity, Tobacco Use Cessation, Smoking Reduction
- Trial name
- POPMIX-Smoking (NCT06458205)
- Testing
- Multi-component intervention for smokers
- Where
- China
- Volunteers
- 4,247 people
- Sponsor
- Peking Union Medical College
Smoking
Pilot Study: Preoperative Nicotine Lozenges
The goal of this pilot study is to determine the feasibility and potential effect size of nicotine lozenges as an adjunct to maintain brief preoperative abstinence, defined as not smoking the day of surgery.
- Trial name
- NCT00586482
- Testing
- Nicotine Lozenge, Abstinence Advisement
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Mayo Clinic
Adolescent - Emotional Problem, Smoking
TRIAD Project: Qualitative Study of Adolescent Depression and Smoking
It has been shown in the adult literature that smoking is related to depression and visa versa. Not much is known about how this relationship is started or if one perhaps leads to the other.
- Trial name
- NCT00592696
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Drexel University College of Medicine
Nicotine Dependence, Depression
Vigorous Exercise for Depressed Smokers
In this project the investigators will develop and pilot test a supervised, vigorous intensity exercise intervention for depressed female smokers.
- Trial name
- NCT01860924
- Testing
- exercise, health education
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Smoking Cessation, HIV
Ending Tobacco Use Through Interactive Tailored Messaging for Cambodian People Living With HIV/AIDS
The goal of this research study is to test how well an automated text messaging smoking treatment program helps smokers with HIV quit smoking.
- Trial name
- ProjectENDIT (NCT05746442)
- Testing
- Smartphone-delivered Automated Messaging, Nicotine patch, Brief Advice to Quit and Smoking Cessation Self Help Materials
- Where
- 3 sites in Cambodia
- Volunteers
- 800 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
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