Clinical trials: Tobacco Smoking
Nasal Polyp, Smoking
The Factors Associated With the Formation of Nasal polyp-a Case Control and Descriptive Study
Nasal polyp is a significant health problem with a prevalence of 4%. It is increased in patients with asthma (7-15%), Cystic fibrosis (39-56%) or aspirin intolerance (36-96%).The quality of life (QOL) is worse than in patients…
- Conditions
- Nasal Polyp, Smoking, Rhinosinusitis, Allergic Rhinitis
- Trial name
- ACAAGSONP (NCT01278719)
- Where
- India
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Karnataka Institute of Medical Sciences
Nicotine Dependence, Cigarettes, Cessation, Tobacco
Reducing Nicotine Addiction in Adolescent Smokers
Adolescents are at risk for tobacco use due to factors such as impulsivity, poor perception, desire to prove themselves, and insufficient neurological development.
- Conditions
- Nicotine Dependence, Cigarettes, Cessation, Tobacco, Cessation, Smoking, Adolescent Problem Behavior
- Trial name
- NCT05477342
- Testing
- Board Game, Tobacco Cesseation Education, Combined İntervention
- Where
- Turkey (Türkiye)
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Ministry of National Education, Turkey
Cigarette Smoking
Puff Biofeedback to Reduce Smoking Reinforcement
The purpose of the study is to examine the effects of a novel bio-behavioral paradigm, entitled, Puff Topography Biofeedback Training, compared to a control condition, in reducing stress-induced smoking reinforcement.
- Trial name
- NCT05644002
- Testing
- Puff Topography Biofeedback Training, Control
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- Rutgers, The State University of New Jersey
Passive Smoking, Tobacco Smoke Pollution
Educational Models for Tobacco Exposure Awareness
This is a randomized controlled trial comparing the effects of peer education and traditional education on increasing knowledge and awareness of secondhand and thirdhand tobacco smoke exposure among geriatric care program…
- Conditions
- Passive Smoking, Tobacco Smoke Pollution, Health Education, Peer Group Guidance
- Trial name
- NCT07473245
- Testing
- Peer Education, traditional education
- Where
- Turkey (Türkiye)
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Chronic Obstructive Pulmonary Disease, Lung Diseases, Obstructive
Impact of Multidisciplinary Care, Structured and Targeted on the COPD Patient's Clinical Pathway.
In 2020, chronic obstructive pulmonary disease (COPD) was the 4th leading cause of death worldwide. In France, its annual cost was estimated at 4366 euros per patient, including 25% related to management of exacerbations and 33%…
- Conditions
- Chronic Obstructive Pulmonary Disease, Lung Diseases, Obstructive, Lung Disease Chronic
- Trial name
- OPTI-BPCO (NCT07907601)
- Testing
- COPD targeted pharmaceutical interview and consultation, Respiratory Insufficiency Day Hospitalization, Pulmonary Function Test
- Where
- France
- Volunteers
- 116 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Cigarette Smoking
Use and Harm Exposure in New Low Nicotine Cigarettes
The proposed research extends previous research on Quest® cigarette smoking behavior by testing whether compensatory smoking occurs as cigarette nicotine level decreases, and whether, as a result, biomarkers of harm exposure…
- Trial name
- NCT01202942
- Testing
- Quest
- Where
- United States
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Major Depressive Disorder, Nicotine Dependence
Sequential Use of Fluoxetine for Smokers With Elevated Depressive Symptoms
The primary purpose of this study is to determine whether, among smokers with elevated depressive symptoms, sequential antidepressant pharmacotherapy with fluoxetine (20 mg) begun 8 weeks prior to and extended throughout standard…
- Conditions
- Major Depressive Disorder, Nicotine Dependence, Depression
- Trial name
- NCT00578669
- Testing
- Fluoxetine, Dextrose
- Where
- United States
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- Butler Hospital
Tobacco Use Cessation
Tobacco Quitlines:Adjunct to Dental Office Tobacco Intervention
The purpose of the study is to compare two methods for providing brief dental office-based interventions designed to help patients quit either cigarette smoking or smokeless tobacco use, and to compare these two dental…
- Trial name
- NCT00384254
- Testing
- 5 A, 3 A
- Where
- United States
- Volunteers
- 2,177 people
- Sponsor
- Oregon Research Institute
Smoking Cessation
Mobile Smoking Treatment for Spanish-speaking Latinx Smokers
The specific aims of the project are to develop and test a Spanish language, mobile app for smoking cessation called Impacto.
- Trial name
- NCT04417075
- Testing
- Impacto (Mobile App), Dejar de Fumar Asistente (Mobile App)
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Houston
Tobacco Use, Tobacco Use Cessation
CONNECT Cancer Survivors With Tobacco Treatment
The purpose of this study is to evaluate the comparative effectiveness of two different informatics-enabled implementation strategies on increasing tobacco treatment and improving smoking cessation rates for cancer control and…
- Conditions
- Tobacco Use, Tobacco Use Cessation, Smoking Cessation, Nicotine Addiction
- Trial name
- NCT07020273
- Testing
- ELEVATE, ELEVATE-S
- Where
- United States
- Volunteers
- 3,543 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Nicotine Vaping
Kick-Nic! Youth Quit Vaping App
High school and middle school students who want to quit vaping will be randomized to receive the Kick-Nic! app or a control NCI website to determine the efficacy of the app for vaping cessation.
- Trial name
- NCT06662305
- Testing
- Kick-Nic! mobile phone application, NCI Quit Vaping website
- Where
- United States
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- Yale University
Copd, COPD Exacerbation
Atorvastatin Effect on Reduction of COPD Exacerbations
It is a randomized, multicenter, prospective, double-blind, placebo controlled, interventional clinical trial that will be conducted in Poland, in about 12 Hospital Pulmonary Departments to evaluate the effectiveness of…
- Conditions
- Copd, COPD Exacerbation, Smoking, Gene Expression
- Trial name
- Captain (NCT04789057)
- Testing
- Atorvastatin 40 Mg Oral Tablet
- Where
- Poland
- Volunteers
- 460 people
- Sponsor
- Medical University of Bialystok
Nicotine Use Disorder, Nicotine Dependence
Baclofen Effects on Smoking Urge and Withdrawal
The purpose of this study is to determine whether baclofen is effective in reducing smoking urge, withdrawal, and reinforcement in moderate to heavy cigarette smokers.
- Conditions
- Nicotine Use Disorder, Nicotine Dependence, Smoking, Tobacco Use Disorder
- Trial name
- NCT00257894
- Testing
- Baclofen
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- VA Office of Research and Development
Smoking Cessation
Clinical Reminder Changes to Increase Smoking Cessation Treatment in Outpatient Psychiatry
This study will use a scientifically robust, mixed-methods, two-arm cluster-randomized study design. Investigators will implement a tobacco use clinical reminder for outpatient psychiatrists practicing at the VA New York Harbor…
- Trial name
- NCT04071795
- Testing
- Opt-Out Reminder, Opt-In Reminder
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- NYU Langone Health
Nicotine Withdrawal
SPECT Imaging of DAT Genotype
A polymorphism in the dopamine transporter (DAT) may determine how much dopamine is available at the synapse and this may affect the underlying reasons for relapse in smokers.
- Trial name
- DDAT (NCT01492322)
- Testing
- TRODAT
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Pennsylvania
Nicotine Dependence
Repetitive Transcranial Magnetic Stimulation (rTMS) for Nicotine Addiction
Cigarette smoking remains a significant public health concern. A magnetic field applied to the outside of the skull can produce electrical activity in the brain without significant pain or the need for anesthesia.
- Trial name
- rTMS (NCT02401672)
- Testing
- Transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Smoking Cessation
Electronic Health Record-Enabled Evidence-Based Smoking Cessation Quality Improvement Implementation Program
The goal of this quality improvement program is to implement, evaluate, and sustain an evidence-based smoking cessation treatment program with a population-based approach so that all patients at the Siteman Cancer Center…
- Trial name
- NCT04107857
- Testing
- ELEVATE enhancement to electronic health record (EHR) to improve cessation counseling offer, ELEVATE enhancement to electronic health record (EHR) to improve smoking cessation medication offer, Data Driven Feedback reports
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Cessation, Smoking
Efficacy of a Smoke-Free Homes Intervention
The purpose of this study is to test whether the integration of a smoke-free homes intervention into the clinical guidelines for tobacco cessation can encourage sustained smoking cessation in low-income primary care patients.
- Trial name
- SFH 5A RCT (NCT04547686)
- Testing
- Smoke-Free Homes Intervention, Quitline
- Where
- United States
- Volunteers
- 916 people
- Sponsor
- Emory University
Healthy
A Relative Bioavailability Study of Carvedilol 12.5 mg Tablets Under Fasting Conditions
To compare the rate and extent of absorption of carvedilol from a test formulation of Carvedilol 12.5 mg Tablets versus the reference Coreg® 12.5 mg Tablets under fasting conditions.
- Trial name
- NCT00864435
- Testing
- Carvedilol 12.5 mg Tablets, single dose, Coreg® 12.5 mg Tablets , single dose
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Actavis Inc.
Tobacco Dependence
Effects of Yoga and Cardiovascular Exercise on Smoking Motivation
The overall purpose of this pilot study is to examine effects of Hatha yoga and cardiovascular exercise on craving, mood, cue reactivity, and smoking behavior.
- Trial name
- NCT01423578
- Testing
- Hatha Yoga (HY), Cardiovascular Exercise (CE), Smoking Cessation Counseling
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
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