Clinical trials: Tobacco Smoking
Smoking, Smoking, Cigarette
Impact of New Standards for Tobacco Products Among Dual E-Cigarette/Combusted Cigarette Users - Project 2
The purpose of the study is to evaluate how limiting the nicotine content in regular cigarettes affects choices for regular cigarette and e-cigarette products.
- Conditions
- Smoking, Smoking, Cigarette, E-Cig Use, Nicotine Dependence
- Trial name
- NCT05473585
- Testing
- very low nicotine content cigarettes, normal nicotine content cigarettes, Study e-cigarette
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Duke University
Smoking
Neuroimaging Attentional Impairment During Abstinence
The broad objective of this proposal is to identify functional neuroanatomical correlates of impairments in sustained attention during smoking abstinence.
- Trial name
- SmokeAtt01 (NCT00692406)
- Testing
- Smoking Abstinence
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Duke University
Smoking Cessation
Benefits of a Cognitive Behavioral Therapy Intervention for Smoking Cessation Supported by Virtual Reality Smoking Cue Exposure
Cognitive-behavioral therapy (CBT) combined with medication is an established intervention for smoking cessation. However, long-term abstinence rates of maximum 35% are yielded.
- Trial name
- ViReTa (NCT03707106)
- Testing
- CBT smoking cessation, virtual reality based cue exposure, progressive muscle relaxation
- Where
- 2 sites in Germany
- Volunteers
- 246 people
- Sponsor
- University Hospital Tuebingen
Smoking Cessation Counseling Ability and Practice
Augmented Reality Animations for Smoking Cessation Counseling Training
This proposed study aims to develop augmented reality (AR) based intervention during the smoking cessation counselling(SCC) training for master nursing students in the University of Hong Kong.
- Trial name
- NCT07024485
- Testing
- AR animations and 5As model based on smoking cessation counseling Knowledge-Attitude-Practice (KAP), 5As model based on smoking cessation counseling Knowledge-Attitude-Practice (KAP)
- Where
- China
- Volunteers
- 50 people
- Sponsor
- The University of Hong Kong
Tobacco Smoking, Oxidative Stress
N-acetylcysteine for Tobacco Smoking
The purpose of this study is to investigate the efficacy of N-acetylcysteine (NAC) for smoking cessation in a double blind, randomized, placebo-controlled trial.
- Conditions
- Tobacco Smoking, Oxidative Stress, Inflammation
- Trial name
- NACNOS (NCT02124525)
- Testing
- N-acetylcysteine
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- Universidade Estadual de Londrina
Smoking, Smoking Behaviors
CSD190501: A Study to Determine Subject Puffing Patterns of an Electronic Nicotine Delivery System in an Ambulatory Setting
This study will be a single-center, controlled, open-label, parallel study to evaluate the puffing patterns of healthy adult consumers of tobacco products switching from a usual brand (UB) Electronic Nicotine Delivery Systems…
- Conditions
- Smoking, Smoking Behaviors, Tobacco Use, Tobacco Smoking
- Trial name
- NCT04226404
- Testing
- CSD1905-11, CSD1905-12, CSD1905-13
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- RAI Services Company
Nicotine Dependence
Extended Varenicline Treatment for Smoking Among Cancer Patients
Upwards of 33-50% of cancer patients who smoked prior to diagnosis continue to smoke following diagnosis and treatment. With medical advances in cancer care yielding a growing constituency of cancer survivors, addressing nicotine…
- Trial name
- NCT01756885
- Testing
- Varenicline, Smoking Cessation Counseling
- Where
- 2 sites in United States
- Volunteers
- 207 people
- Sponsor
- University of Pennsylvania
Nicotine Addiction, Smoking Cessation
Extinction Updating in Reconsolidation
Smoking occurs in approximately 21% of the US population, is responsible for an annual mortality rate of approximately 438,000 citizens, and has an associated healthcare economic burden of $167 billion.
- Trial name
- NCT02154685
- Testing
- Retrieval-Extinction, Non-Retrieval Extinction
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Tobacco Use Disorder, Tobacco Dependence
Equitable Smoking Relapse Prevention
The goal of this clinical trial is to test a GPS (Global Positioning System)-enabled smartphone app (QuitBuddy) in current smokers.
- Trial name
- NCT05625685
- Testing
- Quitbuddy, Control, SDoH Augmentation
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Bryan W. Heckman
Smoking Cessation
Veteran Support for Smoking Cessation Pilot Project (VAntage Pilot)
This is a proposal to conduct a pilot study to assess the feasibility of recruitment of Veteran smoker and support person (SP) dyads and study procedures in preparation for a large randomized pragmatic trial.
- Trial name
- VAntagePilot (NCT04840108)
- Testing
- Support Person Coaching Intervention, Support Person Written Materials
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Minneapolis Veterans Affairs Medical Center
Smoking Cessation, Tobacco Cessation
Effectiveness of the Swedish National Tobacco Quitline
The purpose of this study was to compare the effectiveness of the high-intensity proactive service with the low-intensity reactive service at the Swedish National Tobacco Quitline (SNTQ).
- Trial name
- SNTQ (NCT02085616)
- Testing
- Proactive service, Reactive service
- Where
- 3 sites in Sweden
- Volunteers
- 586 people
- Sponsor
- Uppsala University
Tobacco Use
Comparing an Opt-out to an opt-in Approach for Smoking Cessation in VA Primary Care Clinics
The investigators propose a Type I hybrid effectiveness/implementation study to evaluate two population-based approaches for increasing use of Quitlines and text messaging at two VA sites.
- Trial name
- NCT03477435
- Testing
- Staff training and academic detailing
- Where
- United States
- Volunteers
- 1,365 people
- Sponsor
- VA Office of Research and Development
HIV, COPD
HIV+ Alveolar Macrophage Oxidant-mediated Apoptosis of Pulmonary Endothelium
In HIV+ cigarette smokers, with no prior history of pulmonary infections, emphysema is often developed at an earlier age and is a significant cause of morbidity despite treatment with antiretroviral drugs.
- Conditions
- HIV, COPD, Emphysema, Smoking
- Trial name
- NCT02056158
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Smoking Cessation, Smoking Cessation Intervention
Unraveling the Genetic Basis of Nicotine Addiction for Novel Therapeutic Strategies
This case-control study aims to investigate the genetic and molecular bases of nicotine addiction to identify potential therapeutic targets.
- Conditions
- Smoking Cessation, Smoking Cessation Intervention, Nicotine Addiction, Epigenetics
- Trial name
- NicoGen (NCT06471387)
- Testing
- Flexiquit Smoking Cessation Intervention
- Where
- Cyprus
- Volunteers
- 200 people
- Sponsor
- University of Cyprus
Tobacco
The Abuse Liability of IQOS Heated Tobacco Products Among Adults Who Smoke
This clinical trial aims to evaluate user sensory experiences and smoking behavior when using IQOS heated tobacco products (HTPs) among adults who smoke cigarettes.
- Trial name
- NCT07688304
- Testing
- Smoking Behavioral Research (IQOS), Smoking Behavioral Research (UBC)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Hypertension, Smoking Cessation
Evaluating Effective Methods for Referral for Smoking Cessation Counseling and High Blood Pressure Follow-up
Investigators conducted a clinic-based study to determine the magnitude of uncontrolled hypertension and current smoking in eye doctor's offices and sought to determine if referral to care results in actions taken by the patient.
- Trial name
- NCT03020836
- Testing
- Referral to primary care physician for hypertension control, Referral to smoking quit line
- Volunteers
- 473 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Smoking Cessation
Effectiveness of the Evaluation and Communication of "Pulmonary Age" as Help for Smoking Cessation
The experimental design is a cluster randomized trial in 2 parallel groups: an intervention group with assessment of the pulmonary age and a control group without.
- Trial name
- CAPAST (NCT04276116)
- Testing
- Pulmonary age
- Where
- France
- Volunteers
- 101 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Tobacco Use, Tobacco Smoking
Oral Cannabidiol for Tobacco Cessation
Cannabidiol is a compound found in cannabis plants that is well tolerated, has low abuse liability, and might be an effective medication to promote tobacco cessation.
- Conditions
- Tobacco Use, Tobacco Smoking, Tobacco Dependence, Tobacco Use Disorder
- Trial name
- NCT05445804
- Testing
- 300 mg Cannabidiol, 600 mg Cannabidiol
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Stroke, Smoking Cessation
NICE: NeuroImaging in Cessation Education
The investigators aim to examine the effect on smoking cessation rate by showing stroke patients who are active smokers images of their strokes.
- Trial name
- NCT02769871
- Testing
- Neuroimages of stroke, standardized smoking cessation counseling
- Volunteers
- 20 people
- Sponsor
- Yale University
Vasovagal Syncope, Smoke Inhalation
Relation Between Vasovagal Tendency and Smoking Among University Students
Almost everyone is aware these days is aware about the risk of smoking. Still many people start this habit specially in early life and during college year.
- Trial name
- NCT02949804
- Testing
- Comparison between two groups
- Where
- Jordan
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Jordan Collaborating Cardiology Group
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